Cellules souche et Dérivés
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les voies de signalisation et les protéines impliquées dans le maintien, la différenciation et la prolifération des cellules souches. Ces inhibiteurs sont cruciaux pour comprendre la biologie des cellules souches et pour développer des stratégies visant à manipuler les cellules souches à des fins thérapeutiques, telles que la médecine régénérative et le traitement du cancer. En contrôlant le destin des cellules souches, ces inhibiteurs peuvent aider à orienter la différenciation des cellules souches en types cellulaires spécifiques ou à prévenir une croissance cellulaire indésirable. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de cellules souches de haute qualité pour soutenir vos recherches en biologie des cellules souches, biologie du développement et médecine régénérative.
Sous-catégories appartenant à la catégorie "Cellules souche et Dérivés"
- Gamma-sécrétase(62 produits)
- Hérisson/Smoothened(49 produits)
- Voie de signalisation Hippo(7 produits)
- JAK(247 produits)
- Porc-épic(9 produits)
- ROCK(66 produits)
- STAT(97 produits)
- Cellules souches(461 produits)
- TGF-beta/Smad(60 produits)
- Wnt/beta-caténine(63 produits)
Affichez 2 plus de sous-catégories
680 produits trouvés pour "Cellules souche et Dérivés"
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Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
CAS :<p>Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.</p>Formule :C88H138N20O34P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2082.1Plant 14-3-3-IN-1
Plant 14-3-3-IN-1 (Compound 2) is an inhibitor of the Arabidopsis thaliana 14-3-3 protein, with an IC50 of 1.21 μM. It exhibits varying inhibitory activity against different 14-3-3 isoforms and promotes the closure of leaf stomata.Formule :C22H19NO7SMasse moléculaire :441.08822GSK3-IN-1
CAS :<p>GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.</p>Formule :C14H10ClN3OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :303.77MR44397
<p>MR44397 is a ligand for WD40 repeat (WDR) 5 and is applicable in cancer research.</p>Formule :C23H26N4O2SCouleur et forme :SolidMasse moléculaire :422.54SLLK, Control Peptide for TSP1 Inhibitor(TFA)
CAS :<p>SLLK is a control peptide for LSKL.</p>Formule :C21H41N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.58Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCouleur et forme :Odour SolidRef: TM-L2200
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Couleur et forme :Odour SolidRef: TM-L1600
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demander1(R),2(S)-epoxy Cannabidiol
CAS :1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46SJ1008030 formic
SJ1008030 (compound 8) formic is a selective JAK2 degrader within the PROTAC class, demonstrating efficacy in inhibiting MHH-CALL-4 leukemia cell growth with anFormule :C43H45N13O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :919.96STAT3-IN-31
STAT3-IN-31 (compound K2071), derived from STATtic, acts as an inhibitor of both STAT3 and mitotic processes. This compound interrupts mitotic progression and impacts the formation of the mitotic spindle. Additionally, STAT3-IN-31 hampers migration in glioblastoma cells, suppresses cellular proliferation within tumor spheroids, induces senescence in glioblastoma, and inhibits the growth of Temozolomide-resistant cells while reducing the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein (MCP-1).Formule :C16H15NO3SCouleur et forme :SolidMasse moléculaire :301.36Axltide
CAS :Axltide mimics mouse Insulin receptor substrate 1, amino acids 979-989 with sequence KKSRGDYMTMQIG.Formule :C63H107N19O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1514.77AS2553627
CAS :AS2553627 is a JAK inhibitor. AS2553627 prevents chronic rejection in rat cardiac allografts.Formule :C18H19N5OCouleur et forme :SolidMasse moléculaire :321.38STAT3-IN-34
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.Formule :C19H16N2O4SCouleur et forme :SolidMasse moléculaire :368.41Prafnosbart
CAS :Prafnosbart (DS-6016A) is a humanized IgG1-kappa monoclonal antibody targeting ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1), utilized inCouleur et forme :LiquidGSK3-IN-4
CAS :GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.Formule :C18H20N4ODegré de pureté :98.33%Couleur et forme :SoildMasse moléculaire :308.38Ref: TM-T64366
1mg52,00€5mg111,00€10mg162,00€25mg235,00€50mg330,00€100mg452,00€200mg607,00€1mL*10mM (DMSO)107,00€CK1-IN-3
CAS :WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.Formule :C17H16N2O3SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :328.39Ref: TM-T60005
1mg35,00€5mg74,00€10mg101,00€25mg178,00€50mg258,00€100mg354,00€200mg485,00€1mL*10mM (DMSO)82,00€GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formule :C15H12N4O2SCouleur et forme :SolidMasse moléculaire :312.35Casein kinase 1δ-IN-7
CAS :Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.Formule :C17H14N4O2SDegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :338.38pan-TEAD-IN-1
CAS :pan-TEAD-IN-1 (Compound 3) is an orally active pan-inhibitor of TEAD, disrupting its interaction with coactivators YAP/TAZ by targeting the palmitoylation site of TEAD. This inhibition leads to the downregulation of oncogene transcription, such as Ctgf and Cyr61, within the Hippo signaling pathway. Demonstrating outstanding efficacy, pan-TEAD-IN-1 has an IC50 of 0.36 nM for luciferase and 1.52 nM for H226 cells, along with favorable pharmacokinetic properties (AUC0–∞= 228.7 μg/mL·min, T1/2= 183.9 min). The compound significantly inhibits tumor growth in xenograft models of TEAD-dependent cancers, indicating its potential for research in these cancer types.Formule :C19H16F3NOCouleur et forme :SolidMasse moléculaire :331.33GSK3a-IN-38
CAS :GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.Formule :C18H20N4ODegré de pureté :99.75%Couleur et forme :SoildMasse moléculaire :308.38
