Cellules souches
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les cellules souches et leurs voies de signalisation, affectant leur capacité à s'auto-renouveler et à se différencier. Ces inhibiteurs sont essentiels dans la recherche axée sur le contrôle du comportement des cellules souches, la compréhension des processus de développement et le développement de thérapies pour des maladies comme le cancer, où les cellules souches sont censées jouer un rôle clé. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de cellules souches pour soutenir vos recherches en médecine régénérative, biologie du développement et oncologie.
234 produits trouvés pour "Cellules souches"
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Casein kinase 1δ-IN-8
CAS :Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Formule :C19H14FN5OSDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :379.41TEAD-IN-16
TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with an IC50 of 72.43 μM. This compound plays a significant role in cancer research.
Formule :C16H14F3NO3Masse moléculaire :325.09258Disitertide acetate
Disitertide acetate: a TGF-β1 and PI3K blocker, promotes apoptosis; inhibits receptor interaction.Formule :C70H113N17O24S2Degré de pureté :95.11%Couleur et forme :SoildMasse moléculaire :1640.88STX-0119
CAS :STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.
Formule :C22H14N4O3Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :382.37Fresolimumab
CAS :Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.4 kDaSLLK, Control Peptide for TSP1 Inhibitor(TFA)
CAS :SLLK is a control peptide for LSKL.
Formule :C21H41N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.58TEAD-IN-19
TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, showing inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% for TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at 10 μM. It exhibits strong antiproliferative and antimigratory effects on prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds potential for research in the field of cancer therapeutics.Couleur et forme :Odour SolidMR24
CAS :MR24 is a derivative of G-5555 and acts as an inhibitor of mammalian STE20-like (MST) kinases. It selectively targets MST3 and MST4, with EC50 values of 57 nM and 583 nM, respectively.Formule :C26H29ClN6O3Masse moléculaire :509.00YAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.Formule :C95H148ClN23O23S2Degré de pureté :98.11% - 99.57%Couleur et forme :SoildMasse moléculaire :2079.92Wnt/Hedgehog/Notch Compound Library
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
Couleur et forme :Odour SolidS-Ruxolitinib
CAS :S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.
Formule :C17H18N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.37Jagged-1 (188-204)
CAS :Jagged-1 （188-204）is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin.Formule :C93H127N25O26S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2107.4P17 Peptide
CAS :P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formule :C95H139N27O21Couleur et forme :SolidMasse moléculaire :1995.29WAY-297174
CAS :WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.
Formule :C11H12N2O2S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :268.36YAP-TEAD-IN-3
CAS :YAP-TEAD-IN-3 inhibitor YAP/TAZ-TEAD interactions Avi-human TEAD (4217-434) YAP-TEAD-IN-3 inhibits YAP reporter gene expression and NCI-H2052 cell proliferationFormule :C27H26ClF2N3O4Degré de pureté :97.55% - 98.71%Couleur et forme :SoildMasse moléculaire :529.96HC-258
CAS :HC-258 is a direct TEAD inhibitor covalent Cys380, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 MDA-MB-231.Formule :C20H24N2O2Couleur et forme :SolidMasse moléculaire :324.42NIBR-LTSi
NIBR-LTSi is a selective LATS kinase inhibitor that also activates YAP signaling, promotes tissue stem cell expansion and tissue regeneration in vitro/vivo.Formule :C18H20N4ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :308.38YAP-IN-1
YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.Couleur et forme :Odour SolidLX-7101 hydrochloride
CAS :LX-7101 hydrochloride is a potent LIMK and ROCK2 inhibitor with antihypertensive activity, inhibits LIMK1/2, ROCK, PKA, and can be used to study glaucoma.
Formule :C23H29N7O3xHClDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :487.99Tubastatin
CAS :Tubastatin inhibits TGF-β1-induced S6K phosphorylation, HIF-1α expression and VEG F expression.Formule :C21H22N2O2Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :334.41
