Cellules souches
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les cellules souches et leurs voies de signalisation, affectant leur capacité à s'auto-renouveler et à se différencier. Ces inhibiteurs sont essentiels dans la recherche axée sur le contrôle du comportement des cellules souches, la compréhension des processus de développement et le développement de thérapies pour des maladies comme le cancer, où les cellules souches sont censées jouer un rôle clé. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de cellules souches pour soutenir vos recherches en médecine régénérative, biologie du développement et oncologie.
486 produits trouvés pour "Cellules souches"
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STAT3-IN-31
<p>STAT3-IN-31 (compound K2071), derived from STATtic, acts as an inhibitor of both STAT3 and mitotic processes. This compound interrupts mitotic progression and impacts the formation of the mitotic spindle. Additionally, STAT3-IN-31 hampers migration in glioblastoma cells, suppresses cellular proliferation within tumor spheroids, induces senescence in glioblastoma, and inhibits the growth of Temozolomide-resistant cells while reducing the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein (MCP-1).</p>Formule :C16H15NO3SCouleur et forme :SolidMasse moléculaire :301.36WAY-297174
CAS :<p>WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.</p>Formule :C11H12N2O2S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :268.36TEAD-IN-19
<p>TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, showing inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% for TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at 10 μM. It exhibits strong antiproliferative and antimigratory effects on prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds potential for research in the field of cancer therapeutics.</p>Couleur et forme :Odour SolidWnt pathway inhibitor 3
CAS :<p>Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies</p>Formule :C21H17BrN2O5Degré de pureté :99.69%Couleur et forme :SoildMasse moléculaire :457.27Fasudil
CAS :<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37NIBR-LTSi
<p>NIBR-LTSi is a selective LATS kinase inhibitor that also activates YAP signaling, promotes tissue stem cell expansion and tissue regeneration in vitro/vivo.</p>Formule :C18H20N4ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :308.38ABC99
CAS :<p>ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.</p>Formule :C22H21ClN4O5Degré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :456.88GSK-3β inhibitor 1
CAS :<p>GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.</p>Formule :C14H10N2ODegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :222.24Casein kinase 1δ-IN-6
CAS :<p>CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.</p>Formule :C16H10ClF3N2OSDegré de pureté :99%Couleur et forme :SoildMasse moléculaire :370.78TEAD-IN-16
<p>TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with an IC50 of 72.43 μM. This compound plays a significant role in cancer research.</p>Formule :C16H14F3NO3Masse moléculaire :325.09258Wnt/Hedgehog/Notch Compound Library
<p>A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;</p>Couleur et forme :Odour SolidSLLK, Control Peptide for TSP1 Inhibitor(TFA)
CAS :<p>SLLK is a control peptide for LSKL.</p>Formule :C21H41N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.58Jagged-1 (188-204)
CAS :<p>Jagged-1 （188-204）is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin.</p>Formule :C93H127N25O26S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2107.4Epigenetics Compound Library
<p>Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new</p>Couleur et forme :Odour SolidRBPJ Inhibitor-1
CAS :<p>RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell</p>Formule :C17H14FN3O2Degré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :311.31YAP-IN-1
<p>YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.</p>Couleur et forme :Odour SolidFresolimumab
CAS :<p>Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.4 kDaYW2036
CAS :<p>YW2036 is an inhibitor of Wnt signaling pathway.</p>Formule :C20H16N4ODegré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :328.37Carboxylesterase-IN-2
CAS :<p>Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.</p>Formule :C13H12N4OSDegré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :272.33Casein kinase 1δ-IN-3
CAS :<p>Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.</p>Formule :C17H16N2O2SDegré de pureté :98.94%Couleur et forme :SoildMasse moléculaire :312.39
