VEGFR
Les inhibiteurs du récepteur du facteur de croissance endothélial vasculaire (VEGFR) sont des composés qui bloquent la signalisation du VEGFR, un récepteur clé dans la voie VEGF, cruciale pour l'angiogenèse. Les inhibiteurs de VEGFR empêchent la formation de nouveaux vaisseaux sanguins qui fournissent des nutriments et de l'oxygène aux tumeurs, inhibant ainsi la croissance tumorale. Ces inhibiteurs sont largement utilisés en thérapie et en recherche contre le cancer pour étudier les mécanismes de l'angiogenèse et développer des traitements anticancéreux. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de VEGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
268 produits trouvés pour "VEGFR"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Anti-VEGFR2/KDR Antibody (5U735)
<p>Anti-VEGFR2/KDR Antibody (5U735) is a Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (5U735) can be used in ELISA,FCM.</p>Couleur et forme :Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
<p>VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :24.8 kDa (predicted)Anti-VEGFR2/KDR Antibody-PE (6M522)
<p>Anti-VEGFR2/KDR Antibody-PE (6M522) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (6M522) can be used in FCM.</p>Couleur et forme :Odour LiquidAnti-VEGFR2/KDR Antibody-APC (1T318)
<p>Anti-VEGFR2/KDR Antibody-APC (1T318) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (1T318) can be used in FCM.</p>Couleur et forme :Odour LiquidSU 1498
CAS :Formule :C25H30N2O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :390.53Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805)
<p>Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) is a Rabbit antibody targeting Phospho-VEGF Receptor 2 (Tyr1175). Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) can be used in WB.</p>Couleur et forme :Odour LiquidAnti-VEGFR2/KDR Antibody (9T448)
<p>Anti-VEGFR2/KDR Antibody (9T448) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (9T448) can be used in ELISA.</p>Couleur et forme :Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (hFc)
<p>VEGFR2/KDR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :109 kDa (predicted); 150-160 kDa (reducing condition, due to glycosylation)VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
<p>VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody (6M522)
<p>Anti-VEGFR2/KDR Antibody (6M522) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (6M522) can be used in FCM.</p>Couleur et forme :Odour LiquidAnti-VEGFR2/KDR Antibody (4D988)
<p>Anti-VEGFR2/KDR Antibody (4D988) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4D988) can be used in ELISA.</p>Couleur et forme :Odour LiquidAnti-VEGFR2/KDR Antibody-PE (4B612)
<p>Anti-VEGFR2/KDR Antibody-PE (4B612) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (4B612) can be used in FCM.</p>Couleur et forme :Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
<p>VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody-FITC (4B612)
<p>Anti-VEGFR2/KDR Antibody-FITC (4B612) is a FITC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-FITC (4B612) can be used in FCM.</p>Couleur et forme :Odour LiquidCediranib
CAS :Formule :C25H27FN4O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :450.51Anti-VEGFR2/KDR Antibody-APC (5U735)
<p>Anti-VEGFR2/KDR Antibody-APC (5U735) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (5U735) can be used in FCM.</p>Couleur et forme :Odour LiquidCZC-8004
CAS :<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34Regorafenib
CAS :<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Formule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82JNJ-38158471
CAS :<p>JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .</p>Formule :C15H17ClN6O3Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :364.79VEGFR-2-IN-5
CAS :<p>VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.</p>Formule :C19H24N8Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :364.45BMS-794833
CAS :<p>BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.</p>Formule :C23H15ClF2N4O3Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :468.84Gandotinib
CAS :<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formule :C23H25ClFN7ODegré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :469.94ZD-4190
CAS :<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Formule :C19H16BrFN6O2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :459.27SKLB1002
CAS :<p>SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.</p>Formule :C13H12N4O2S2Degré de pureté :98.51% - >99.99%Couleur et forme :SolidMasse moléculaire :320.39Lenvatinib mesylate
CAS :<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Formule :C22H23ClN4O7SDegré de pureté :99.03% - 99.79%Couleur et forme :SolidMasse moléculaire :522.96PF 477736
CAS :<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48OSI-930
CAS :<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44Regorafenib monohydrate
CAS :<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83VEGFR2-IN-2
CAS :<p>VEGFR2-IN-2 has anti-inflammatory and analgesic activities.</p>Formule :C15H11BrN2ODegré de pureté :99.504%Couleur et forme :SolidMasse moléculaire :315.16Ripretinib
CAS :<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Formule :C24H21BrFN5O2Degré de pureté :99.07% - 99.38%Couleur et forme :SolidMasse moléculaire :510.36XL092
CAS :<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Formule :C29H25FN4O5Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :528.53TAK-659 hydrochloride
CAS :<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Formule :C17H22ClFN6ODegré de pureté :99.28% - 99.82%Couleur et forme :SolidMasse moléculaire :380.85CP-673451
CAS :<p>CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other</p>Formule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5(Z)-Guggulsterone
CAS :<p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>Formule :C21H28O2Degré de pureté :98.93% - 99.72%Couleur et forme :SolidMasse moléculaire :312.45Tanshinone IIA
CAS :<p>Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.</p>Formule :C19H18O3Degré de pureté :99.04% - >99.99%Couleur et forme :Cherry CrystalMasse moléculaire :294.34Dovitinib lactate hydrate
CAS :<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Takeda-6d
CAS :<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Formule :C27H19ClFN5O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :547.99AZD4547
CAS :<p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>Formule :C26H33N5O3Degré de pureté :99.37% - 99.88%Couleur et forme :SolidMasse moléculaire :463.57Vandetanib
CAS :<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35PD173074
CAS :<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Pamufetinib mesylate
CAS :<p>Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.</p>Formule :C28H27FN4O7S2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :614.67TAK-593
CAS :<p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>Formule :C23H23N7O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :445.47Bevacizumab
CAS :<p>Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.</p>Degré de pureté :95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :146.53 kDaIsolinderalactone
CAS :<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Formule :C15H16O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :244.29PP121
CAS :<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formule :C17H17N7Degré de pureté :98.45% - 99.67%Couleur et forme :SolidMasse moléculaire :319.36SU4312
CAS :<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Formule :C17H16N2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :264.32Semaxinib
CAS :<p>Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.</p>Formule :C15H14N2ODegré de pureté :99.84%Couleur et forme :Yellow To Yellow OrangeMasse moléculaire :238.28ZM 306416
CAS :<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Formule :C16H13ClFN3O2Degré de pureté :99.37% - ≥95%Couleur et forme :SolidMasse moléculaire :333.74Vatalanib free base
CAS :<p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>Formule :C20H15ClN4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :346.81Sodium taurocholate
CAS :<p>Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.</p>Formule :C26H44NO7S·NaDegré de pureté :95% - 99.64%Couleur et forme :White PowderMasse moléculaire :537.69Midostaurin
CAS :<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64SU14813
CAS :<p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>Formule :C23H27FN4O4Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :442.48MGCD-265 analog
CAS :<p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>Formule :C26H20FN5O2S2Degré de pureté :98.06% - 98.68%Couleur et forme :SolidMasse moléculaire :517.6R1530
CAS :<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Formule :C18H14ClFN4ODegré de pureté :98.422%Couleur et forme :SolidMasse moléculaire :356.78Ribociclib
CAS :<p>Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).</p>Formule :C23H30N8ODegré de pureté :97.91% - >99.99%Couleur et forme :SolidMasse moléculaire :434.54SAR131675
CAS :<p>SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.</p>Formule :C18H22N4O4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :358.39Nintedanib esylate
CAS :<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Formule :C31H33N5O4·C2H6O3SDegré de pureté :99.43% - 99.96%Couleur et forme :SolidMasse moléculaire :649.76Ki20227
CAS :<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Formule :C24H24N4O5SDegré de pureté :98.97% - 99.88%Couleur et forme :SolidMasse moléculaire :480.54Tyrphostin A9
CAS :<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Formule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38LY2874455
CAS :<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Formule :C21H19Cl2N5O2Degré de pureté :97.22% - 99.46%Couleur et forme :SolidMasse moléculaire :444.31Telatinib
CAS :<p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>Formule :C20H16ClN5O3Degré de pureté :97.61% - 99.81%Couleur et forme :SolidMasse moléculaire :409.83Altiratinib
CAS :<p>Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,</p>Formule :C26H21F3N4O4Degré de pureté :99.67% - 99.75%Couleur et forme :SolidMasse moléculaire :510.46SU5408
CAS :<p>SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.</p>Formule :C18H18N2O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :310.35Gamabufotalin
CAS :<p>Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.</p>Formule :C24H34O5Degré de pureté :99.18% - 99.51%Couleur et forme :SolidMasse moléculaire :402.52WHI-P180
CAS :<p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>Formule :C16H15N3O3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :297.31SU 5402
CAS :<p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32SKLB 610
CAS :<p>SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,</p>Formule :C21H16F3N3O3Degré de pureté :99.33% - 99.83%Couleur et forme :SolidMasse moléculaire :415.37SU5204
CAS :<p>SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and</p>Formule :C17H15NO2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :265.31Tivozanib
CAS :<p>Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.</p>Formule :C22H19ClN4O5Degré de pureté :98.08% - 99.67%Couleur et forme :SolidMasse moléculaire :454.86MAZ51
CAS :<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Formule :C21H18N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :314.38AZD2932
CAS :<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Formule :C24H25N5O4Degré de pureté :97.71% - 98.37%Couleur et forme :SolidMasse moléculaire :447.49AMG-47a
CAS :<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Xanthatin
CAS :<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3Dovitinib lactate
CAS :<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Formule :C24H27FN6O4Degré de pureté :99.54% - 99.77%Couleur et forme :SolidMasse moléculaire :482.51AAL-993
CAS :<p>AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.</p>Formule :C20H16F3N3ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :371.36RAF265
CAS :<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formule :C24H16F6N6ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :518.41NVP-BAW2881
CAS :<p>NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.</p>Formule :C22H15F3N4O2Degré de pureté :98.19% - 99.97%Couleur et forme :SolidMasse moléculaire :424.38SU5205
CAS :<p>SU5205 is a VEGFR2 inhibitor.</p>Formule :C15H10FNODegré de pureté :99.62% - 99.67%Couleur et forme :SolidMasse moléculaire :239.24Foretinib
CAS :<p>Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.</p>Formule :C34H34F2N4O6Degré de pureté :98.07% - 99.68%Couleur et forme :SolidMasse moléculaire :632.65Vorolanib
CAS :<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Formule :C23H26FN5O3Degré de pureté :97.35%Couleur et forme :SolidMasse moléculaire :439.48Fruquintinib
CAS :<p>Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-</p>Formule :C21H19N3O5Degré de pureté :98.84% - 99.89%Couleur et forme :SolidMasse moléculaire :393.39Orantinib
CAS :<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formule :C18H18N2O3Degré de pureté :98.92% - 99.52%Couleur et forme :SolidMasse moléculaire :310.35AG-13958
CAS :<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Formule :C26H22FN7ODegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :467.5Motesanib
CAS :<p>Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.</p>Formule :C22H23N5ODegré de pureté :98% - 99.09%Couleur et forme :SolidMasse moléculaire :373.45KRN-633
CAS :<p>KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.</p>Formule :C20H21ClN4O4Degré de pureté :99.53% - 99.73%Couleur et forme :SolidMasse moléculaire :416.86JI-101
CAS :<p>JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.</p>Formule :C22H20BrN5O2Degré de pureté :99.41% - 99.97%Couleur et forme :SolidMasse moléculaire :466.33Ilorasertib
CAS :<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54Cediranib
CAS :<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51SCR-1481B1
CAS :<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Formule :C32H40ClF2N6O13PDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :821.12Oglufanide
CAS :<p>Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).</p>Formule :C16H19N3O5Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :333.34EOC317
CAS :<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Formule :C27H26F5N7O3Degré de pureté :98.00% - 99.26%Couleur et forme :SolidMasse moléculaire :591.53SU5208
CAS :<p>SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).</p>Formule :C13H9NOSDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :227.28Linifanib
CAS :<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4GW786034B
CAS :<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98KI8751
CAS :<p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>Formule :C24H18F3N3O4Degré de pureté :99.22% - 99.9%Couleur et forme :SolidMasse moléculaire :469.41Vatalanib dihydrochloride
CAS :<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Formule :C20H15ClN4·2HClDegré de pureté :99.16%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :419.73CYC-116
CAS :<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46Golvatinib
CAS :<p>Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor</p>Formule :C33H37F2N7O4Degré de pureté :98.24% - ≥95%Couleur et forme :SolidMasse moléculaire :633.69Ningetinib Tosylate
CAS :<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formule :C38H37FN4O8SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :728.79Ponatinib
CAS :<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56
