VEGFR
Les inhibiteurs du récepteur du facteur de croissance endothélial vasculaire (VEGFR) sont des composés qui bloquent la signalisation du VEGFR, un récepteur clé dans la voie VEGF, cruciale pour l'angiogenèse. Les inhibiteurs de VEGFR empêchent la formation de nouveaux vaisseaux sanguins qui fournissent des nutriments et de l'oxygène aux tumeurs, inhibant ainsi la croissance tumorale. Ces inhibiteurs sont largement utilisés en thérapie et en recherche contre le cancer pour étudier les mécanismes de l'angiogenèse et développer des traitements anticancéreux. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de VEGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
244 produits trouvés pour "VEGFR"
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SKLB1002
CAS :Formule :C13H12N4O2S2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :320.39Regorafenib
CAS :Formule :C21H15ClF4N4O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :482.82Sorafenib Tosylate
CAS :Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :637.03NVP-BHG 712
CAS :Formule :C26H20F3N7ODegré de pureté :>95.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :503.49Axitinib
CAS :Formule :C22H18N4OSDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :386.47Axitinib
CAS :Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formule :C22H18N4OSDegré de pureté :98.9% - 99.74%Couleur et forme :Off-White SolidMasse moléculaire :386.47SKLB1002
CAS :Formule :C13H12N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.3900Albendazole
CAS :Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formule :C12H15N3O2SDegré de pureté :98.21% - 98.76%Couleur et forme :Colorless Crystals SolidMasse moléculaire :265.33Sunitinib Malate
CAS :Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Formule :C26H33FN4O7Degré de pureté :98% - 99.26%Couleur et forme :SolidMasse moléculaire :532.56Sorafenib
CAS :Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formule :C21H16ClF3N4O3Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :464.82Sunitinib
CAS :Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Formule :C22H27FN4O2Degré de pureté :98% - 99.67%Couleur et forme :Yellow SolidMasse moléculaire :398.47Sorafenib tosylate
CAS :Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :99.24% - 99.94%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :637.03PTC299
CAS :PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormule :C25H20Cl2N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :467.34Ref: TM-T12574
1mg111,00€5mg230,00€1mL*10mM (DMSO)236,00€10mg350,00€25mg590,00€50mg838,00€100mg1.144,00€WHI-P154
CAS :Formule :C16H14BrN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.2047(E)-2-Cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
CAS :Formule :C25H30N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.5179PD 173074
CAS :Formule :C28H41N7O3Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :523.67022H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS :Formule :C15H14N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :238.2845Chloropyramine hydrochloride
CAS :Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Formule :C16H20ClN3·HClDegré de pureté :99.45% - 99.8%Couleur et forme :SolidMasse moléculaire :326.26GW806742X
CAS :GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.Formule :C25H22F3N7O4SDegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :573.55Parsatuzumab
CAS :Parsatuzumab (RG 7414), a monoclonal antibody targeting EGFL7, an immunomodulator.Parsatuzumab inhibits the interaction of EGFL7 with endothelial cells.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :148.22 kDaIcrucumab
CAS :Icrucumab, a humanized antibody, inhibits VEGFR-1 and shows antitumor effects, tested in metastatic colon cancer.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :150 kDaLucitanib
CAS :Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Formule :C26H25N3O4Degré de pureté :96.13%Couleur et forme :SolidMasse moléculaire :443.49Ref: TM-T15185
1mg46,00€2mg59,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg255,00€50mg462,00€100mg672,00€Pazopanib
CAS :Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formule :C21H23N7O2SDegré de pureté :98.78% - 99.85%Couleur et forme :White PowderMasse moléculaire :437.52Ref: TM-T0097L
1mL*10mM (DMSO)33,00€10mg42,00€25mg66,00€50mg90,00€100mg137,00€200mg225,00€500mg313,00€2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS :Formule :C21H15ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.8154Ref: IN-DA00ICN3
100gÀ demander10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€1g131,00€5g255,00€50g617,00€10g619,00€Naphazoline hydrochloride
CAS :Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.Formule :C14H15ClN2Degré de pureté :97.93%Couleur et forme :White Crystalline Powder White Crystalline PowderMasse moléculaire :246.74Lenvatinib
CAS :Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formule :C21H19ClN4O4Degré de pureté :98.46% - 99.96%Couleur et forme :SolidMasse moléculaire :426.85Pamufetinib
CAS :Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.Formule :C27H23FN4O4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :518.56Ref: TM-T13108
1mg52,00€5mg101,00€1mL*10mM (DMSO)127,00€10mg149,00€25mg244,00€50mg359,00€100mg510,00€200mg695,00€Chloramphenicol
CAS :Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formule :C11H12Cl2N2O5Degré de pureté :99.6% - 99.84%Couleur et forme :Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMasse moléculaire :323.13Acrizanib
CAS :Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.Formule :C20H18F3N7O2Degré de pureté :98.71% - 99.64%Couleur et forme :SolidMasse moléculaire :445.4Ref: TM-T5373
1mg105,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg401,00€25mg685,00€50mg954,00€100mg1.243,00€Motesanib Diphosphate
CAS :Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormule :C22H23N5O·2H3PO4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :569.445Z-7-Oxozeaenol
CAS :5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.Formule :C19H22O7Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :362.37VEGF-IN-1
VEGF-IN-1 (compound 6) reduces the release of VEGF in U87-MG cells and inhibits angiogenesis in vitro. Additionally, it suppresses cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM against U87-MG cells.Formule :C27H22Cl2N4RuCouleur et forme :SolidMasse moléculaire :574.47VEGFR-2-IN-29
CAS :VEGFR-2-IN-29 is a VEGFR2 inhibitor.Formule :C16H11N3O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :293.28VEGFR-2-IN-59
VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 μM, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.Formule :C19H20N6O4Couleur et forme :SolidMasse moléculaire :396.4Sozinibercept
CAS :Sozinibercept (OPT 302; VGX-300), a VEGFR-3 inhibitor, blocks VEGF-C/D to curb angiogenesis and vascular leakage, and treats rat diabetic retinal edema.Couleur et forme :LiquidAngiogenesis related Compound Library
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and highCouleur et forme :Odour SolidRef: TM-L4800
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderAbicipar pegol
CAS :Abicipar pegol is an anti-VEGF DARPin for ocular diseases, reducing retinal thickness and leakage.Couleur et forme :LiquidFDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Couleur et forme :LiquidPulocimab
CAS :Pulocimab, an anti-VEGFR2 monoclonal antibody (mAb), is utilized in cancer research [1].Couleur et forme :LiquidTovecimig
Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4.Couleur et forme :Odour LiquidVEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.Couleur et forme :Odour SolidConbercept
CAS :Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDRDegré de pureté :98%Couleur et forme :LiquidKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Couleur et forme :Odour SolidRef: TM-L1600
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderTyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCouleur et forme :Odour SolidRef: TM-L2200
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderVulinacimab
CAS :Vulinacimab (HLX-06) is a mAb targeting VEGFR-2, used in cancer research, vital for tumor angiogenesis and endothelial cell functions.Couleur et forme :LiquidOlinvacimab
CAS :Olinvacimab (TTAC-0001) is a human monoclonal antibody targeting VEGFR-2/KDR with anti-angiogenic activity that blocks tumor angiogenesis.Degré de pureté :97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :148.16 kDaProtein LMWP
CAS :Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research forFormule :C72H142N44O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1880.18KLTWQELYQLKYKGI
CAS :KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors.Formule :C92H143N21O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1911.25Arginyl-Glutamine
CAS :Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.Formule :C11H22N6O4Degré de pureté :95.2%Couleur et forme :SolidMasse moléculaire :302.33
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