VEGFR
Les inhibiteurs du récepteur du facteur de croissance endothélial vasculaire (VEGFR) sont des composés qui bloquent la signalisation du VEGFR, un récepteur clé dans la voie VEGF, cruciale pour l'angiogenèse. Les inhibiteurs de VEGFR empêchent la formation de nouveaux vaisseaux sanguins qui fournissent des nutriments et de l'oxygène aux tumeurs, inhibant ainsi la croissance tumorale. Ces inhibiteurs sont largement utilisés en thérapie et en recherche contre le cancer pour étudier les mécanismes de l'angiogenèse et développer des traitements anticancéreux. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de VEGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
244 produits trouvés pour "VEGFR"
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VEGFR2/KDR Protein, Human, Recombinant (His)
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :95.9%Couleur et forme :Lyophilized PowderMasse moléculaire :84.6 kDa (predicted); 120-130 kDa (reducing condition, due to glycosylation)Cediranib Maleate
CAS :Formule :C25H27FN4O3·C4H4O4Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :566.59JK-P3
CAS :Formule :C18H17N3O3Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :323.35Pazopanib Hydrochloride
CAS :Formule :C21H23N7O2S·HClDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :473.98Nintedanib
CAS :Formule :C31H33N5O4Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Yellow to Yellow green powder to crystalMasse moléculaire :539.64Sunitinib Malate
CAS :Formule :C22H27FN4O2·C4H6O5Degré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Brown powder to crystalMasse moléculaire :532.57Cediranib
CAS :Formule :C25H27FN4O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :450.51Pazopanib
CAS :Formule :C21H23N7O2SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :437.52Linifanib
CAS :Formule :C21H18FN5ODegré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :375.41VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :35.9 kDa (predicted)VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :50.4 kDa (predicted)Anti-VEGFR2/KDR Antibody-PE (1T318)
Anti-VEGFR2/KDR Antibody-PE (1T318) is a PE-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (1T318) can be used in FCM.Couleur et forme :Odour LiquidRegorafenib Hydrochloride
CAS :Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formule :C21H16Cl2F4N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :519.28Regorafenib
CAS :Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82Ref: TM-T1792
5mg34,00€10mg49,00€1mL*10mM (DMSO)54,00€25mg75,00€50mg90,00€100mg137,00€200mg175,00€500mg294,00€JNJ-38158471
CAS :JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formule :C15H17ClN6O3Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :364.79Ref: TM-T22349
1mg38,00€5mg78,00€1mL*10mM (DMSO)84,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€VEGFR-2-IN-5
CAS :VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formule :C19H24N8Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :364.45Ref: TM-T2056
1mg90,00€5mg222,00€1mL*10mM (DMSO)224,00€10mg333,00€25mg560,00€50mg797,00€100mg1.071,00€BMS-794833
CAS :BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.Formule :C23H15ClF2N4O3Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :468.84Gandotinib
CAS :LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formule :C23H25ClFN7ODegré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :469.94ZD-4190
CAS :ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Formule :C19H16BrFN6O2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :459.27Ref: TM-T5475
1mg80,00€5mg173,00€1mL*10mM (DMSO)175,00€10mg261,00€25mg414,00€50mg567,00€100mg767,00€200mg1.018,00€SKLB1002
CAS :SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.Formule :C13H12N4O2S2Degré de pureté :98.51% - >99.99%Couleur et forme :SolidMasse moléculaire :320.39Lenvatinib mesylate
CAS :Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formule :C22H23ClN4O7SDegré de pureté :99.03% - 99.79%Couleur et forme :SolidMasse moléculaire :522.96PF 477736
CAS :PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48OSI-930
CAS :OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44Regorafenib monohydrate
CAS :Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83Ref: TM-T1792L
5mg34,00€10mg46,00€1mL*10mM (DMSO)55,00€25mg65,00€50mg94,00€100mg133,00€200mg197,00€500mg329,00€VEGFR2-IN-2
CAS :VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formule :C15H11BrN2ODegré de pureté :99.504%Couleur et forme :SolidMasse moléculaire :315.16Ref: TM-T9724
1mg35,00€5mg73,00€1mL*10mM (DMSO)93,00€10mg105,00€25mg195,00€50mg311,00€100mg445,00€200mg617,00€Ripretinib
CAS :Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formule :C24H21BrFN5O2Degré de pureté :99.07% - 99.62%Couleur et forme :SolidMasse moléculaire :510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€1mL*10mM (DMSO)202,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€XL092
CAS :XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
Formule :C29H25FN4O5Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :528.53(Z)-Guggulsterone
CAS :(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formule :C21H28O2Degré de pureté :98.93% - 99.72%Couleur et forme :SolidMasse moléculaire :312.45Tanshinone IIA
CAS :Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Formule :C19H18O3Degré de pureté :99.04% - >99.99%Couleur et forme :Cherry CrystalMasse moléculaire :294.34Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Takeda-6d
CAS :Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formule :C27H19ClFN5O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :547.99Ref: TM-T22436
1mg92,00€2mg128,00€5mg178,00€1mL*10mM (DMSO)243,00€10mg268,00€25mg439,00€50mg610,00€100mg820,00€200mg1.099,00€Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg50,00€1mL*10mM (DMSO)52,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€PD173074
CAS :PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Ref: TM-T2642
5mg40,00€10mg54,00€1mL*10mM (DMSO)56,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€TAK-593
CAS :TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formule :C23H23N7O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :445.47Ref: TM-T16975
2mg42,00€5mg62,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg182,00€50mg284,00€100mg409,00€200mg575,00€Bevacizumab
CAS :Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Degré de pureté :95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :146.53 kDaRef: TM-T9904
1mg127,00€2mg202,00€5mg376,00€10mg560,00€25mg895,00€50mg1.216,00€100mg1.634,00€200mg2.213,00€Isolinderalactone
CAS :Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formule :C15H16O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :244.29PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.36SU4312
CAS :SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.Formule :C17H16N2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :264.32Semaxinib
CAS :Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Formule :C15H14N2ODegré de pureté :99.84%Couleur et forme :Yellow To Yellow OrangeMasse moléculaire :238.28ZM 306416
CAS :ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).Formule :C16H13ClFN3O2Degré de pureté :99.37% - ≥95%Couleur et forme :SolidMasse moléculaire :333.74Vatalanib free base
CAS :Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formule :C20H15ClN4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :346.81Sodium taurocholate
CAS :Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Formule :C26H44NO7S·NaDegré de pureté :95% - 99.64%Couleur et forme :White PowderMasse moléculaire :537.69Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€SU14813
CAS :SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formule :C23H27FN4O4Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :442.48MGCD-265 analog
CAS :Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formule :C26H20FN5O2S2Degré de pureté :98.06% - 98.68%Couleur et forme :SolidMasse moléculaire :517.6R1530
CAS :R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formule :C18H14ClFN4ODegré de pureté :98.422%Couleur et forme :SolidMasse moléculaire :356.78Ref: TM-TQ0317
1mg39,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg264,00€50mg423,00€100mg640,00€SAR131675
CAS :SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formule :C18H22N4O4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)79,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€Nintedanib esylate
CAS :Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormule :C31H33N5O4·C2H6O3SDegré de pureté :99.43% - 99.98%Couleur et forme :SolidMasse moléculaire :649.76Ki20227
CAS :Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formule :C24H24N4O5SDegré de pureté :98.97% - 99.88%Couleur et forme :SolidMasse moléculaire :480.54Ref: TM-T4315
1mg44,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€Tyrphostin A9
CAS :Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38
