Src
Les inhibiteurs de Src sont des composés qui ciblent les kinases de la famille Src, impliquées dans divers processus cellulaires, notamment la croissance, la différenciation et l'angiogenèse. Les kinases Src jouent un rôle crucial dans les voies de signalisation qui favorisent la formation de nouveaux vaisseaux sanguins dans les tumeurs. Inhiber Src peut perturber ces voies, réduisant ainsi l'angiogenèse et la croissance tumorale. Les inhibiteurs de Src sont largement utilisés dans la recherche sur le cancer et le développement thérapeutique. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de Src de haute qualité pour soutenir vos recherches en oncologie, signalisation cellulaire et angiogenèse.
78 produits trouvés pour "Src"
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Dasatinib
CAS :Formule :C22H26ClN7O2SDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :488.01NVP-BHG 712
CAS :Formule :C26H20F3N7ODegré de pureté :>95.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :503.49Dasatinib monohydrate
CAS :<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Formule :C22H28ClN7O3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :506.03CSF1R-IN-2
CAS :<p>CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).</p>Formule :C20H20FN7O2Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :409.42WHI-P154
CAS :Formule :C16H14BrN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.2047Adrenalone hydrochloride
CAS :<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formule :C9H11NO3·HClDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :217.65Hck-IN-1
CAS :<p>Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.</p>Formule :C16H11ClN6O3SDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :402.81Dasatinib
CAS :<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01Ref: IN-DA00AP0L
1gÀ demander1mg51,00€5mg68,00€10mg80,00€25mg102,00€50mg126,00€100mg193,00€250mg273,00€Tirbanibulin Mesylate
CAS :<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C27H33N3O6SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :527.63Bosutinib
CAS :<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Hck-IN-2
<p>Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.</p>Formule :C36H35FN6O10Couleur et forme :SolidMasse moléculaire :730.696Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
CAS :<p>Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.</p>Formule :C32H46N5O17PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :803.71Tyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Couleur et forme :Odour SolidKinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Couleur et forme :Odour SolidSecretin, canine
CAS :<p>Secretin: endocrine hormone, increases bicarbonate-rich pancreatic fluid, regulates canine gastric functions via Src kinase pathway.</p>Formule :C131H222N44O41Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3069.43Caffeic acid-pYEEIE
CAS :<p>Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,).</p>Formule :C39H50N5O19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :923.82LCB 03-0110 dihydrochloride
CAS :<p>LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2</p>Formule :C24H25Cl2N3O2SDegré de pureté :99.9%Couleur et forme :SoildMasse moléculaire :490.45PP 2
CAS :Formule :C15H16ClN5Degré de pureté :>97.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :301.781-Naphthyl PP1
CAS :Formule :C19H19N5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :317.40Saracatinib
CAS :Formule :C27H32ClN5O5Degré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :542.03WHI-P154
CAS :Formule :C16H14BrN3O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :376.21Bosutinib
CAS :Formule :C26H29Cl2N5O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :530.45PP 1
CAS :Formule :C16H19N5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :281.36AP23846
CAS :<p>AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.</p>Formule :C24H34N5OPDegré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :439.53A-770041
CAS :<p>A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.</p>Formule :C34H39N9O3Degré de pureté :99.23% - 99.86%Couleur et forme :SolidMasse moléculaire :621.73Anti-Src Antibody (1E789)
<p>Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.</p>Couleur et forme :Odour LiquidsquarunkinA
CAS :<p>squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-</p>Formule :C25H32F3N5O4Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :523.55PP121
CAS :<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formule :C17H17N7Degré de pureté :98.45% - 99.67%Couleur et forme :SolidMasse moléculaire :319.36AMG-47a
CAS :<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Scutellarein
CAS :<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Formule :C15H10O6Degré de pureté :98.02% - 99.63%Couleur et forme :SolidMasse moléculaire :286.24Spebrutinib
CAS :<p>Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic</p>Formule :C22H22FN5O3Degré de pureté :97.02% - >99.99%Couleur et forme :SolidMasse moléculaire :423.441-Naphthyl PP1 hydrochloride
CAS :<p>1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src</p>Formule :C19H20ClN5Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :353.85ENMD-2076
CAS :<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47RK-24466
CAS :<p>RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.</p>Formule :C23H22N4ODegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :370.45PF 477736
CAS :<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48Masitinib
CAS :<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64SU6656
CAS :<p>SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.</p>Formule :C19H21N3O3SDegré de pureté :98.21% - 98.73%Couleur et forme :SolidMasse moléculaire :371.45PP2
CAS :<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77PD-161570
CAS :<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Formule :C26H35Cl2N7ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :532.51β-Hydroxyisovalerylshikonin
CAS :<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Formule :C21H24O7Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :388.41Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71Pyridostatin
CAS :<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formule :C31H32N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.64AD80
CAS :<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Formule :C22H19F4N7ODegré de pureté :99.49% - 99.75%Couleur et forme :SolidMasse moléculaire :473.43Tolimidone
CAS :<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Formule :C11H10N2O2Degré de pureté :99.85% - 99.85%Couleur et forme :SolidMasse moléculaire :202.21eCF506
CAS :<p>eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)</p>Formule :C26H38N8O3Degré de pureté :97.85% - 98.16%Couleur et forme :SolidMasse moléculaire :510.63Rebastinib
CAS :<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formule :C30H28FN7O3Degré de pureté :99.53% - 99.79%Couleur et forme :SolidMasse moléculaire :553.59UM-164
CAS :<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formule :C30H31F3N8O3SDegré de pureté :98.72% - 99.52%Couleur et forme :SolidMasse moléculaire :640.68Saracatinib
CAS :<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.031-Naphthyl PP1
CAS :<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Formule :C19H19N5Degré de pureté :99.85%Couleur et forme :White Cyrstalline SolidMasse moléculaire :317.39
