c-Kit
Les inhibiteurs de c-Kit sont des composés qui bloquent l'activité du Récepteur du Facteur de Cellules Souches (c-Kit), une tyrosine kinase jouant un rôle crucial dans la survie, la prolifération et la différenciation cellulaires, en particulier dans les cellules hématopoïétiques. Les mutations de c-Kit sont liées à divers cancers, notamment les tumeurs stromales gastro-intestinales (GIST) et la leucémie. Chez CymitQuimica, nous proposons des inhibiteurs de c-Kit pour soutenir vos recherches en oncologie, hématologie et biologie des cellules souches.
117 produits trouvés pour "c-Kit"
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Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Lenvatinib
CAS :Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formule :C21H19ClN4O4Degré de pureté :98.46% - 99.96%Couleur et forme :SolidMasse moléculaire :426.85Axitinib
CAS :Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formule :C22H18N4OSDegré de pureté :98.9% - 99.74%Couleur et forme :Off-White SolidMasse moléculaire :386.47N-Desmethyl imatinib
CAS :N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.58Ref: TM-T11641
1mg87,00€5mg166,00€1mL*10mM (DMSO)170,00€10mg303,00€25mg512,00€50mg737,00€100mg1.018,00€Pazopanib
CAS :Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formule :C21H23N7O2SDegré de pureté :98.78% - 99.85%Couleur et forme :White PowderMasse moléculaire :437.52Ref: TM-T0097L
1mL*10mM (DMSO)33,00€10mg42,00€25mg66,00€50mg90,00€100mg137,00€200mg225,00€500mg313,00€JI6
CAS :JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.Formule :C19H17N3O4SDegré de pureté :98.51%Couleur et forme :SoildMasse moléculaire :383.42Eglatoprutug
CAS :Eglatoprutug is a humanized immunoglobulin G1-kappa monoclonal antibody targeting the c-Kit receptor [1].Couleur et forme :LiquidKG5
CAS :KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).
Formule :C20H16F3N7OSDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :459.45c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Formule :C25H28FN5O5Couleur et forme :SolidMasse moléculaire :497.52M4205
CAS :M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formule :C29H32N8ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :508.62Ref: TM-T9689
1mg50,00€5mg110,00€1mL*10mM (DMSO)122,00€10mg170,00€25mg290,00€50mg414,00€100mg572,00€200mg772,00€Amuvatinib hydrochloride
CAS :Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.Formule :C23H22ClN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.97Motesanib Diphosphate
CAS :Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormule :C22H23N5O·2H3PO4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :569.44Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,Formule :C19H15N5O2SCouleur et forme :SolidMasse moléculaire :377.42Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Couleur et forme :Odour LiquidAnti-C-Kit Antibody (9Y519)
Anti-C-Kit Antibody (9Y519) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (9Y519) can be used in ELISA.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-FITC (7P530)
Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.Couleur et forme :Odour LiquidN-Desethyl Sunitinib
CAS :N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Formule :C20H23FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.42SU14813 maleate
CAS :SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formule :C27H31FN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.56Anti-CD117 Antibody (9H202)
Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (8E724)
Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-PE (8E724)
Anti-C-Kit Antibody-PE (8E724) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (8E724) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (7P530)
Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-APC (1R766)
Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Couleur et forme :Odour Liquidc-Kit/CD117 Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Degré de pureté :97.1%Couleur et forme :Lyophilized PowderMasse moléculaire :82 kDa (predicted); 93-115 kDa (reducing conditions)c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Couleur et forme :Lyophilized PowderMasse moléculaire :56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)Telatinib mesylate
CAS :Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formule :C21H20ClN5O6SCouleur et forme :SolidMasse moléculaire :505.93c-Kit/CD117 Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :99.4%Couleur et forme :Lyophilized PowderMasse moléculaire :56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :98.2%Couleur et forme :Lyophilized PowderMasse moléculaire :57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :17.9 kDa (predicted); 18 kDa (reducing conditions)c-Kit/CD117 Protein, Human, Recombinant (aa 540-972, His & GST)
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag.Couleur et forme :Lyophilized PowderMasse moléculaire :76.8 kDa (predicted); 68 kDa (reducing conditions)PLX647
CAS :PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formule :C21H17F3N4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :382.38Ref: TM-T1925
2mg39,00€5mg57,00€1mL*10mM (DMSO)60,00€10mg86,00€25mg127,00€50mg178,00€100mg264,00€200mg389,00€c-Kit/CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Couleur et forme :Lyophilized PowderMasse moléculaire :56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.Anti-C-Kit Antibody (6X205)
Anti-C-Kit Antibody (6X205) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (6X205) can be used in ELISA.Couleur et forme :Odour LiquidAnti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Couleur et forme :Odour LiquidDovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43ISCK03
CAS :ISCK03 is a selective SCF/c-Kit inhibitor.Formule :C19H21N3O2SDegré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :355.45JNJ-38158471
CAS :JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formule :C15H17ClN6O3Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :364.79Ref: TM-T22349
1mg38,00€5mg78,00€1mL*10mM (DMSO)84,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€OSI-930
CAS :OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64Toceranib Phosphate
CAS :Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formule :C22H28FN4O6PDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :494.45BLU-263
CAS :BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formule :C27H29FN10ODegré de pureté :99.01% - 99.67%Couleur et forme :SolidMasse moléculaire :528.58Ripretinib
CAS :Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formule :C24H21BrFN5O2Degré de pureté :99.07% - 99.62%Couleur et forme :SolidMasse moléculaire :510.36Ref: TM-T8482
1mg71,00€2mg92,00€5mg157,00€1mL*10mM (DMSO)192,00€10mg260,00€25mg409,00€50mg655,00€100mg1.063,00€200mg1.459,00€SU14813
CAS :SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formule :C23H27FN4O4Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :442.48Avapritinib
CAS :Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formule :C26H27FN10Degré de pureté :96.59% - 99.7%Couleur et forme :SolidMasse moléculaire :498.56Ref: TM-T5109
1mg35,00€5mg75,00€10mg114,00€1mL*10mM (DMSO)172,00€25mg222,00€50mg334,00€100mg557,00€200mg790,00€Multi-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€Ki20227
CAS :Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formule :C24H24N4O5SDegré de pureté :98.97% - 99.88%Couleur et forme :SolidMasse moléculaire :480.54Ref: TM-T4315
1mg44,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€Flumatinib
CAS :Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formule :C29H29F3N8ODegré de pureté :99.39% - 99.95%Couleur et forme :SolidMasse moléculaire :562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€1mL*10mM (DMSO)82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€AZD2932
CAS :AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formule :C24H25N5O4Degré de pureté :97.71% - 98.37%Couleur et forme :SolidMasse moléculaire :447.49AZD3229 Tosylate
CAS :AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFormule :C31H34FN7O6SCouleur et forme :SolidMasse moléculaire :651.71Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€Dovitinib lactate
CAS :Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formule :C24H27FN6O4Degré de pureté :99.54% - 99.77%Couleur et forme :SolidMasse moléculaire :482.51Ref: TM-T7104
5mg49,00€1mL*10mM (DMSO)54,00€10mg74,00€25mg122,00€50mg202,00€100mg339,00€200mg507,00€500mg800,00€Tandutinib
CAS :Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formule :C31H42N6O4Degré de pureté :99.45% - ≥98%Couleur et forme :White SolidMasse moléculaire :562.7Vimseltinib
CAS :Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formule :C23H25N7O2Degré de pureté :99.05% - 99.57%Couleur et forme :SolidMasse moléculaire :431.49Ref: TM-T10652
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€SKLB4771
CAS :SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formule :C25H27N7O3S2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€1mL*10mM (DMSO)148,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€AZD3229
CAS :AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.Formule :C24H26FN7O3Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :479.51Ref: TM-T5409
1mg44,00€5mg87,00€1mL*10mM (DMSO)99,00€10mg140,00€25mg248,00€50mg364,00€100mg509,00€200mg698,00€c-Kit-IN-1
CAS :c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formule :C26H21F2N5O3Degré de pureté :98.72% - 98.73%Couleur et forme :SolidMasse moléculaire :489.47Ref: TM-T4332
1mg37,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg224,00€50mg353,00€100mg578,00€200mg797,00€Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :99.42% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.60Telatinib
CAS :Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formule :C20H16ClN5O3Degré de pureté :97.61% - 99.81%Couleur et forme :SolidMasse moléculaire :409.83Linifanib
CAS :Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Ref: TM-T2514
5mg48,00€1mL*10mM (DMSO)50,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€GW786034B
CAS :Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98N-Desethylsunitinib hydrochloride
CAS :N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formule :C20H24ClFN4O2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :406.88JNK-IN-8
CAS :JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).Formule :C29H29N7O2Degré de pureté :99.24% - >99.99%Couleur et forme :SolidMasse moléculaire :507.59Ref: TM-T2668
2mg44,00€5mg73,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg197,00€50mg326,00€100mg482,00€200mg685,00€CP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€KI8751
CAS :KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formule :C24H18F3N3O4Degré de pureté :99.22% - 99.9%Couleur et forme :SolidMasse moléculaire :469.41Ref: TM-T2446
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg81,00€25mg147,00€50mg279,00€100mg447,00€200mg635,00€GNF-5837
CAS :GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).Formule :C28H21F4N5O2Degré de pureté :97.26% - 98.08%Couleur et forme :SolidMasse moléculaire :535.49Ref: TM-T6097
5mg48,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg117,00€50mg178,00€100mg295,00€200mg384,00€500mg622,00€Motesanib
CAS :Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formule :C22H23N5ODegré de pureté :98% - 99.09%Couleur et forme :SolidMasse moléculaire :373.45Ref: TM-T2288
5mg34,00€1mL*10mM (DMSO)39,00€10mg49,00€25mg81,00€50mg114,00€100mg160,00€200mg230,00€500mg389,00€Gilteritinib
CAS :Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formule :C29H44N8O3Degré de pureté :97.75% - 99.90%Couleur et forme :SolidMasse moléculaire :552.71Ref: TM-T4409
1mg38,00€2mg52,00€5mg85,00€10mg114,00€25mg177,00€50mg261,00€100mg411,00€500mg954,00€1g1.288,00€Regorafenib
CAS :Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82Ref: TM-T1792
5mg34,00€10mg49,00€1mL*10mM (DMSO)54,00€25mg75,00€50mg90,00€100mg137,00€200mg175,00€500mg294,00€Lenvatinib mesylate
CAS :Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formule :C22H23ClN4O7SDegré de pureté :99.03% - 99.79%Couleur et forme :SolidMasse moléculaire :522.96Tyrphostin AG1296
CAS :Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formule :C16H14N2O2Degré de pureté :99.94% - >99.99%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T6711
2mg40,00€5mg58,00€1mL*10mM (DMSO)81,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Amuvatinib
CAS :Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formule :C23H21N5O3SDegré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :447.51Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€1mL*10mM (DMSO)49,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€Cabozantinib
CAS :Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formule :C28H24FN3O5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :501.51Flumatinib mesylate
CAS :Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formule :C30H33F3N8O4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :658.69Ref: TM-T7861
1mg34,00€5mg84,00€10mg126,00€1mL*10mM (DMSO)132,00€25mg236,00€50mg371,00€100mg595,00€500mg1.234,00€Cabozantinib hydrochloride
CAS :Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€Masitinib mesylate
CAS :Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formule :C29H34N6O4S2Degré de pureté :97.67% - 98.44%Couleur et forme :SolidMasse moléculaire :594.75Sitravatinib
CAS :Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.68Ref: TM-T4349
5mg49,00€1mL*10mM (DMSO)69,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€AST 487
CAS :AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formule :C26H30F3N7O2Degré de pureté :98.17% - 99.56%Couleur et forme :SolidMasse moléculaire :529.56Ref: TM-T4053
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€c-Kit/CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Couleur et forme :Lyophilized PowderMasse moléculaire :58.60 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00805
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Toceranib
CAS :Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formule :C22H25FN4O2Degré de pureté :97.62%Couleur et forme :SolidMasse moléculaire :396.46Barzolvolimab
CAS :Barzolvolimab (CDX 0159) is a humanized monoclonal antibody targeting KIT that reduces skin mast cells and disease activity in chronic inducible urticaria.Degré de pureté :95% - 95.6% (SDS-PAGE); 95.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.63 kDaBriquilimab
CAS :Briquilimab is a humanized antibody that inhibits the SCF-KIT interaction, inducing mast cell apoptosis for research into inflammatory diseases.Degré de pureté :95% - 96.0% (SDS-PAGE); 96.0% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.56 KDaAnti-Mouse CD117 Antibody
Anti-Mouse CD117 Antibody, a rat-derived IgG2b isotype, acts as an inhibitor specific to the mouse CD117 antigen.Degré de pureté :98%Couleur et forme :Odour LiquidDovitinib Dilactic Acid
CAS :Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.Formule :C21H21FN6O·2C3H6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.59KBP-7018 HCl
CAS :KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Formule :C31H31ClN4O5Couleur et forme :SolidMasse moléculaire :575.06c-Kit-IN-3
CAS :c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).Formule :C26H20ClF3N2O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :516.9Ref: TM-T10651
1mg82,00€5mg154,00€10mg240,00€1mL*10mM (DMSO)316,00€25mg396,00€50mg532,00€100mg745,00€500mg1.494,00€GW694590A
CAS :GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].Formule :C22H19N5O4Couleur et forme :SolidMasse moléculaire :417.42Sitravatinib malate
CAS :Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5
Formule :C37H35F2N5O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :763.76Bezuclastinib
CAS :Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.Formule :C19H17N5ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :331.37KI-328
CAS :KI-328: novel selective KIT kinase inhibitor; blocks Wt/mutant-KIT cell growth; low effect on D816V-KIT.Formule :C25H25N7O3Couleur et forme :SolidMasse moléculaire :471.51
