Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1424 produits trouvés pour "Autophagie"
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Tricyclic cytosine tC
CAS :<p>Tricyclic cytosine (tC) is a fluorescent analog of cytosine designed for RNA imaging within live cells, facilitating the study of RNA synthesis, degradation,</p>Formule :C15H15N3O5SCouleur et forme :SolidMasse moléculaire :349.36PDEδ autophagic degrader 1
<p>PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.</p>Formule :C41H42Br2IN7O5Masse moléculaire :997.06589Zn-DPA-maytansinoid conjugate 1
<p>Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.</p>Formule :C115H145ClN18O31S2Zn2Couleur et forme :SolidMasse moléculaire :2505.83CXCR4 antagonist 1
CAS :<p>CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.</p>Formule :C27H43N7Couleur et forme :SolidMasse moléculaire :465.69(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH
<p>(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), consisting of Thalidomide and the corresponding Linker. It functions as a Cereblon ligand to recruit the CRBN protein and serves as a crucial intermediate for synthesizing complete PROTAC molecules.</p>Formule :C27H32N8O5Masse moléculaire :548.24957p62-ZZ Ligand-Linker Conjugate 1
CAS :<p>p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.</p>Formule :C31H42N2O6Couleur et forme :SolidMasse moléculaire :538.68(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc
<p>(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. This compound serves as a Cereblon ligand to recruit CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formule :C31H41N5O6Masse moléculaire :579.30568EthD-III
<p>EthD-III: red fluorescent nucleic acid probe; stains dead cells; binds to DNA in cells with damaged membranes; Ex/Em=530/645 nm.</p>Formule :C51H62Cl5N9Couleur et forme :SolidMasse moléculaire :978.36Cy5.5-SE (DIPEA)
<p>Cy5.5-SE DIPEA is a water-soluble CY dye often used for labeling proteins and antibodies, with simple mixing for conjugation. Store protected from light.</p>Formule :C53H66N4O16S4Couleur et forme :SolidMasse moléculaire :1143.37HDAC-IN-62
<p>HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.</p>Formule :C15H14N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.35Beclin1-Bcl-2 interaction inhibitor 1
<p>Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].</p>Couleur et forme :Odour SolidRCP168
<p>RCP168 is a highly selective and potent CXCR4 receptor antagonist with an IC50 of 5 nM. It exhibits superior capacity to inhibit HIV-1 (Human Immunodeficiency Virus type 1) from entering host cells via the CXCR4 receptor compared to natural chemokines. RCP168 suppresses HIV-1 infection by blocking viral binding sites or inducing receptor internalization. It can be utilized in research to study interactions between the CXCR4 receptor and other chemokine receptors.</p>Formule :C365H585N105O95S5Masse moléculaire :8119.27766Episilvestrol
CAS :<p>Episilvestrol is a derivative of silvestrol with eIF4A-targeted antitumor properties, found in Aglaia silvestris fruits and twigs.</p>Formule :C34H38O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.66Corydalmine hydrochloride
CAS :<p>Corydalmine hydrochloride: antifungal, oral analgesic, soothes neuropathic pain by blocking NF-κB/CXCL1/CXCR2.</p>Formule :C20H24ClNO4Couleur et forme :SolidMasse moléculaire :377.86AUTAC2
CAS :<p>AUTAC2, an FKBP12-targeting AUTAC, contains FBnG and SLF, with SLF non-covalently binding FKBP12.</p>Formule :C61H81FN10O14SCouleur et forme :SolidMasse moléculaire :1229.42CXCL8 (54-72)
<p>CXCL8 (54-72) is a C-terminal peptide segment of the chemokine CXCL8. This peptide features a long, highly positively charged C-terminal region that interacts with the negative charges on glycosaminoglycans (GAG) to facilitate binding. CXCL8 (54-72) inhibits neutrophil adhesion and migration, as well as adhesion to endothelial cells. It is useful in studying the role of chemokines in inflammatory responses.</p>Formule :C107H173N33O30Masse moléculaire :2400.30261CXCR4-IN-3
<p>CXCR4-IN-3 (compound XVI) is an orally active inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. It exhibits potent anti-chemotactic effects, with an inhibition rate of 79.19±2.33%. Additionally, CXCR4-IN-3 possesses anti-inflammatory properties and can be utilized in research on IBD (inflammatory bowel disease).</p>CCR7 antagonist 1
<p>CCR7 antagonist1 (30c) functions as a dual antagonist, targeting CXCR2 with an IC50 of 11.02 μM and CCR7 with an IC50 of 0.43 μM.</p>Formule :C13H22N6OSMasse moléculaire :310.15758(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc
<p>(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. It acts as a Cereblon ligand, recruiting CRBN proteins, and serves as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formule :C30H39N5O6Masse moléculaire :565.29003Autophagy/REV-ERB-IN-1
<p>Autophagy/REV-ERB-IN-1 is a dual inhibitor of autophagy and REV-ERB. It exhibits antitumor activity, with a CC50 value of 2.3 μM in BTB-474 cells.</p>Formule :C24H30F2N2Masse moléculaire :384.23771Antitumor agent-133
<p>Antitumor agent-133 (compound 4d) is a bis-santine derivative that demonstrates activity against Huh1 (IC50 = 17.13 μM) and Huh7 (IC50 = 8.27 μM). It induces autophagy and inhibits tumor growth by modulating the levels of the LC3BII, ATG5, and p62 proteins.</p>Formule :C27H24Br2N4O8Masse moléculaire :689.99609Bam 12P
CAS :<p>Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.</p>Formule :C62H97N21O16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1424.64Ch55-O-C3-NH2
CAS :<p>Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR.</p>Formule :C27H35NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.57Cyanine 5 Tyramide methyl indole
<p>Cyanine 5 Tyramide is a red dye used in HRP assays and nucleic acid hybridization. Store away from light.</p>Formule :C40H47N3O8S2Couleur et forme :SolidMasse moléculaire :761.95N6-Isopentenyladenosine
CAS :<p>N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.</p>Formule :C15H21N5O4Degré de pureté :97.13% - 99.69%Couleur et forme :SolidMasse moléculaire :335.36(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
<p>(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate combining an E3 ligase ligand with a linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding Linker. This compound functions as a Cereblon ligand, recruiting the CRBN protein and serving as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formule :C29H36N8O6Masse moléculaire :592.27578Olaparib-d5
CAS :<p>Olaparib D5 is a deuterium labeled Olaparib. Olaparib is a potent and oral inhibitor of PARP.</p>Formule :C24H23FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.49Dexamethasone-d5
CAS :<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Formule :C22H24D5FO5Couleur et forme :SolidMasse moléculaire :397.49Imatinib D4
CAS :<p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>Formule :C29H31N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.63Bexarotene D4
CAS :<p>Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.</p>Formule :C24H28O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.5Trimetazidine
CAS :<p>Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.</p>Formule :C14H22N2O3Degré de pureté :99.9%Couleur et forme :Hite Or Off-White Crystalline PowderMasse moléculaire :266.34Binimetinib-13C-d3
<p>Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.</p>Formule :C17H15BrF2N4O3Couleur et forme :SolidMasse moléculaire :445.24Pyrazinamide-d3
CAS :<p>Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.</p>Formule :C5D3H2N3OCouleur et forme :SolidMasse moléculaire :126.13Omeprazole-d3
CAS :<p>Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)</p>Formule :C17H19N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.44LG100268
CAS :<p>LG100268 is a selective, and oral RXR agonist，inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.</p>Formule :C24H29NO2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :363.49Enzalutamide-d3
CAS :<p>Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.</p>Formule :C21H16F4N4O2SCouleur et forme :SolidMasse moléculaire :467.45TRAF6 peptide TFA
<p>TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.</p>Formule :C145H238N34O44·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3161.64 (free acid)Isoniazid-d4
CAS :<p>Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.</p>Formule :C6H3D4N3OCouleur et forme :SolidMasse moléculaire :141.16Rapalink-1
CAS :<p>Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.</p>Formule :C91H138N12O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1784.14Erlotinib-d6 hydrochloride
CAS :<p>Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.</p>Formule :C22H24ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.93Ponatinib-d8
CAS :<p>Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).</p>Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.61Anti-LRRK2 Antibody (1C773)
<p>Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.</p>Couleur et forme :Odour LiquidEzetimibe-d4
CAS :<p>Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation</p>Formule :C24H21F2NO3Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :413.45Tetrahydrocurcumin D6
CAS :<p>Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.</p>Formule :C21H24O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.45Manzamine A
CAS :<p>Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.</p>Formule :C36H44N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.775PS372424 hydrochloride
CAS :<p>PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.</p>Formule :C33H45ClN6O4Degré de pureté :95.03%Couleur et forme :SolidMasse moléculaire :625.2Idelalisib D5
CAS :<p>Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.</p>Formule :C22H18FN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.45Ladarixin
CAS :<p>Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.</p>Formule :C11H12F3NO6S2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :375.34Rosuvastatin D3 Sodium
CAS :<p>Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).</p>Formule :C22H24D3FN3NaO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.54Cilengitide TFA
CAS :<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68Saquinavir mesylate
CAS :<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Formule :C39H54N6O8SDegré de pureté :99.19%Couleur et forme :White Or Pale Yellow PowderMasse moléculaire :766.9GW406108X
CAS :<p>GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.</p>Formule :C20H11Cl2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.21R1487 Hydrochloride
CAS :<p>R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.</p>Formule :C19H19ClF2N4O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :424.83Gemcitabine elaidate
CAS :<p>Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with</p>Formule :C27H43F2N3O5Couleur et forme :SolidMasse moléculaire :527.64Curcumin-d6
CAS :<p>Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a</p>Formule :C21H20O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.422Heparin Lithium
CAS :<p>Heparin Lithium salt is an anticoagulant that reversibly binds to ATIII and enhances its inhibitory effect on coagulation factor(thrombin and factor Xa).</p>Formule :C14H25NO20S3Couleur et forme :SolidMasse moléculaire :623.01321Aliskiren
CAS :<p>Aliskiren (CGP 60536) is a renin inhibitor (IC50: 1.5 nM) with antihypertensive activity and is used in the treatment of various cardiovascular diseases.</p>Formule :C30H53N3O6Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :551.76THZ-P1-2
CAS :<p>THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.</p>Formule :C31H29N7O2Couleur et forme :SolidMasse moléculaire :531.61Br-DAPI
CAS :<p>IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.</p>Formule :C16H14BrN5Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :356.22OR-1855
CAS :<p>OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.</p>Formule :C11H13N3ODegré de pureté :98%Couleur et forme :Pale Yellow SolidMasse moléculaire :203.24Rapamycin-d3
CAS :<p>Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).</p>Formule :C51H79NO13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :917.19V-9302 hydrochloride
CAS :<p>V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.</p>Formule :C34H39ClN2O4Degré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :575.14IKK 16 hydrochloride
CAS :<p>IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.</p>Formule :C28H30ClN5OSCouleur et forme :SolidMasse moléculaire :520.09ACT-1004-1239
CAS :<p>ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.</p>Formule :C27H28F2N6O3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :522.55ATI-2341
CAS :<p>ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.</p>Formule :C104H178N26O25S2Couleur et forme :SolidMasse moléculaire :2256.82CXCR2 antagonist 8
CAS :<p>CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.</p>Formule :C14H13N3O5Couleur et forme :SolidMasse moléculaire :303.27Motixafortide
CAS :<p>Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).</p>Formule :C97H144FN33O19S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2159.52Cediranib maleate
CAS :<p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>Formule :C29H31FN4O7Couleur et forme :SolidMasse moléculaire :566.58Resveratrol analog 1
CAS :<p>Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.</p>Formule :C14H11FO2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :230.23Megestrol Acetate-d3
CAS :<p>Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.</p>Formule :C24H29D3O4Couleur et forme :SolidMasse moléculaire :387.53Rupatadine
CAS :<p>Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.</p>Formule :C26H26ClN3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :415.96Rosuvastatin Sodium
CAS :<p>Rosuvastatin Sodium: HMGCR inhibitor, blocks hERG (IC50: 11 nM, 195 nM), reduces hERG expression, hinders Hsp70-hERG interaction.</p>Formule :C22H27FN3NaO6SCouleur et forme :SolidMasse moléculaire :503.52Metformin-d6 hydrochloride
CAS :<p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>Formule :C4H12ClN5Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :171.66Nilotinib-d6
CAS :<p>Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.</p>Formule :C28H22F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.55Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Formule :C39H57N13O8S2·xC2HF3O2Couleur et forme :SolidMasse moléculaire :900.08 (free base)LY2510924
CAS :<p>LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).</p>Formule :C62H88N14O10Couleur et forme :SolidMasse moléculaire :1189.45Afatinib D6
CAS :<p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>Formule :C24H25ClFN5O3Couleur et forme :SolidMasse moléculaire :491.98Gefitinib-d8
CAS :<p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.</p>Formule :C22H24ClFN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.95Brivanib
CAS :<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Formule :C19H19FN4O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :370.38Silibinin-d3
<p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>Formule :C25H22O10Couleur et forme :SolidMasse moléculaire :485.46Regorafenib-d3
CAS :<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Formule :C21H15ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.83KN-93 hydrochloride
CAS :<p>KN-93 hydrochloride is a cell-permeable, reversible and competitive calmodulin-dependent kinase type II ( CaMKII ) inhibitor with a K i of 370 nM.</p>Formule :C26H30Cl2N2O4SCouleur et forme :SolidMasse moléculaire :537.5Loperamide-d6 hydrochloride
CAS :<p>Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.</p>Formule :C29H34Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.54Pemetrexed disodium heptahydrate
CAS :<p>Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.</p>Formule :C20H33N5Na2O13Degré de pureté :99.783%Couleur et forme :SolidMasse moléculaire :597.49Levomepromazine
CAS :<p>Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.</p>Formule :C19H24N2OSDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :328.47Ginkgolide K
CAS :<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Formule :C20H22O9Degré de pureté :99.44% - 99.72%Couleur et forme :SolidMasse moléculaire :406.38Ginsenoside F2
CAS :<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Formule :C42H72O13Degré de pureté :99.04% - 99.3%Couleur et forme :SolidMasse moléculaire :785.01Valproic Acid
CAS :<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formule :C8H16O2Degré de pureté :97.78% - 99%Couleur et forme :Colourless To Pale Yellow Liquid ViscousMasse moléculaire :144.21Momelotinib
CAS :<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formule :C23H22N6O2Degré de pureté :97.47% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46TBHQ
CAS :<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formule :C10H14O2Degré de pureté :99.17% - 99.53%Couleur et forme :White Solid PowderMasse moléculaire :166.22Clematichinenoside AR
CAS :<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Formule :C82H134O43Degré de pureté :99.04% - 99.69%Couleur et forme :SolidMasse moléculaire :1807.92Actein
CAS :<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Formule :C37H56O11Degré de pureté :≥98%Couleur et forme :Brown PowderMasse moléculaire :676.83Selenomethionine
CAS :<p>DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.</p>Formule :C5H11NO2SeDegré de pureté :98% - 99.95%Couleur et forme :Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidMasse moléculaire :196.11Dimethyl fumarate
CAS :<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formule :C6H8O4Degré de pureté :90.51% - >99.99%Couleur et forme :White To Off-White Powder White Crystalline PowderMasse moléculaire :144.13Hoechst 33342
CAS :<p>Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!</p>Formule :C27H28N6ODegré de pureté :98.12% - 99.75%Couleur et forme :Yellow-Green PowderMasse moléculaire :452.55ABT-751
CAS :<p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>Formule :C18H17N3O4SDegré de pureté :98.84% - 99.50%Couleur et forme :SolidMasse moléculaire :371.41GNE0877
CAS :<p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>Formule :C14H16F3N7Degré de pureté :98.01% - 99.97%Couleur et forme :SolidMasse moléculaire :339.32Autophinib
CAS :<p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>Formule :C14H11ClN6O3Degré de pureté :99.25% - 99.41%Couleur et forme :SolidMasse moléculaire :346.73Corynoxine
CAS :<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formule :C22H28N2O4Degré de pureté :96.83% - 99.93%Couleur et forme :SolidMasse moléculaire :384.47STO-609
CAS :<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formule :C19H10N2O3Degré de pureté :97.14% - 98.8%Couleur et forme :SolidMasse moléculaire :314.29JMS-17-2 hydrochloride
CAS :<p>JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.</p>Formule :C25H27Cl2N3OCouleur et forme :SolidMasse moléculaire :456.41Brevilin A
CAS :<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Formule :C20H26O5Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :346.42Tempol
CAS :<p>Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.</p>Formule :C9H18NO2Degré de pureté :97% - 99.74%Couleur et forme :4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMasse moléculaire :172.25CHIR-99021
CAS :<p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>Formule :C22H18Cl2N8Degré de pureté :97.94% - ≥95%Couleur et forme :SolidMasse moléculaire :465.34Bergapten
CAS :<p>Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.</p>Formule :C12H8O4Degré de pureté :99.48% - ≥95%Couleur et forme :Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Masse moléculaire :216.19Tanespimycin
CAS :<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formule :C31H43N3O8Degré de pureté :99.07% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.69IOWH-032
CAS :<p>IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.</p>Formule :C22H15Br2N3O4Degré de pureté :98.92% - ≥95%Couleur et forme :SolidMasse moléculaire :545.18Sinomenine
CAS :<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formule :C19H23NO4Degré de pureté :99.02% - 99.73%Couleur et forme :White PowderMasse moléculaire :329.39Dantrolene
CAS :<p>Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.</p>Formule :C14H10N4O5Degré de pureté :99.97%Couleur et forme :Crystals From Aq DimethylformamideMasse moléculaire :314.25Isorhapontigenin
CAS :<p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>Formule :C15H14O4Degré de pureté :98.49% - 99.85%Couleur et forme :Off White Crystals PowerMasse moléculaire :258.27Pinocembrin
CAS :<p>Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.</p>Formule :C15H12O4Degré de pureté :99.61% - >99.99%Couleur et forme :SolidMasse moléculaire :256.25MW-150 dihydrochloride dihydrate
CAS :<p>MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.</p>Formule :C24H29Cl2N5O2Couleur et forme :SolidMasse moléculaire :490.43Cediranib
CAS :<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51Tubastatin A Hydrochloride
CAS :<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Formule :C20H21N3O2·HClDegré de pureté :97.24% - 99.15%Couleur et forme :SolidMasse moléculaire :371.86Quizartinib
CAS :<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Formule :C29H32N6O4SDegré de pureté :98% - 99.42%Couleur et forme :SolidMasse moléculaire :560.67Apigenin
CAS :<p>Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.</p>Formule :C15H10O5Degré de pureté :97.64% - 99.66%Couleur et forme :Yellow Needles From Aqueous Pyridine SolidMasse moléculaire :270.24U0126-EtOH
CAS :<p>U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!</p>Formule :C18H16N6S2·C2H6ODegré de pureté :99.72% - 99.88%Couleur et forme :SolidMasse moléculaire :426.6Tenovin-6
CAS :<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Formule :C25H34N4O2SDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :454.63AZD1208
CAS :<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48U0126
CAS :<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Formule :C18H16N6S2Degré de pureté :99.61%Couleur et forme :White SolidMasse moléculaire :380.49Torin 1
CAS :<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Formule :C35H28F3N5O2Degré de pureté :98.3% - 99.33%Couleur et forme :SolidMasse moléculaire :607.62Ligustilide
CAS :<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Formule :C12H14O2Degré de pureté :96.03% - 98.14%Couleur et forme :Yellow Brown PowderMasse moléculaire :190.24Pinosylvin
CAS :<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formule :C14H12O2Degré de pureté :99.89% - 99.91%Couleur et forme :SolidMasse moléculaire :212.24Berbamine dihydrochloride
CAS :<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Formule :C37H42Cl2N2O6Degré de pureté :95% - 99.99%Couleur et forme :SolidMasse moléculaire :681.65Isosorbide Mononitrate
CAS :<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Formule :C6H9NO6Degré de pureté :98.16%Couleur et forme :Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMasse moléculaire :191.14Entinostat
CAS :<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Formule :C21H20N4O3Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :376.41CCT128930 hydrochloride
CAS :<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Formule :C18H21Cl2N5Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :378.3Gartanin
CAS :<p>Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.</p>Formule :C23H24O6Degré de pureté :99.64% - 99.85%Couleur et forme :SolidMasse moléculaire :396.43KB-R7943 mesylate
CAS :<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Formule :C17H21N3O6S2Degré de pureté :99.88% - ≥95%Couleur et forme :SolidMasse moléculaire :427.5PTC-209 hydrobromide
CAS :<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formule :C17H13Br2N5OS·HBrDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :576.1Autogramin-1
CAS :<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Formule :C23H27N5O5SDegré de pureté :97.69% - 99.25%Couleur et forme :SolidMasse moléculaire :485.56XL388
CAS :<p>XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.</p>Formule :C23H22FN3O4SDegré de pureté :99.39% - 99.53%Couleur et forme :SolidMasse moléculaire :455.5NSC 185058
CAS :<p>NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.</p>Formule :C11H9N3SDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :215.27PF-543 hydrochloride
CAS :<p>PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2</p>Formule :C27H32ClNO4SDegré de pureté :98.9% - 99.93%Couleur et forme :SolidMasse moléculaire :502.1URMC-099
CAS :<p>URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.</p>Formule :C27H27N5Degré de pureté :99.32% - 99.98%Couleur et forme :SolidMasse moléculaire :421.54Autocamtide-2-related inhibitory peptide
CAS :<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Formule :C64H116N22O19Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :1497.74PF-06447475
CAS :<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Formule :C17H15N5ODegré de pureté :98.61% - 99.62%Couleur et forme :SolidMasse moléculaire :305.33Onjisaponin B
CAS :<p>Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-</p>Formule :C75H112O35Degré de pureté :99.20% - 99.972%Couleur et forme :SolidMasse moléculaire :1573.67A-867744
CAS :<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Formule :C20H19ClN2O3SDegré de pureté :95.66%Couleur et forme :SolidMasse moléculaire :402.89Briciclib
CAS :<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Formule :C19H23O10PSDegré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :474.42TA-01
CAS :<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formule :C20H12F3N3Degré de pureté :99.55% - 99.94%Couleur et forme :SolidMasse moléculaire :351.32PI3Kδ-IN-15
CAS :<p>CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ.</p>Formule :C21H16FN7ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :401.4Lanatoside C
CAS :<p>Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.</p>Formule :C49H76O20Degré de pureté :98.3% - >99.99%Couleur et forme :SolidMasse moléculaire :985.12Spautin-1
CAS :<p>Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.</p>Formule :C15H11F2N3Degré de pureté :97.69% - 98.99%Couleur et forme :SolidMasse moléculaire :271.26Sofalcone
CAS :<p>Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.</p>Formule :C27H30O6Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :450.52Hesperadin
CAS :<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formule :C29H32N4O3SDegré de pureté :98.04% - 99.44%Couleur et forme :SolidMasse moléculaire :516.65Nitroprusside disodium dihydrate
CAS :<p>Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.</p>Formule :C5H4FeN6Na2O3Degré de pureté :98%Couleur et forme :Bright RedMasse moléculaire :297.95UNC1999
CAS :<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formule :C33H43N7O2Degré de pureté :99.19% - >99.99%Couleur et forme :SolidMasse moléculaire :569.74SAR405
CAS :<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Formule :C19H21ClF3N5O2Degré de pureté :99.42% - 99.79%Couleur et forme :SolidMasse moléculaire :443.85AZ304
CAS :<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Formule :C27H25N5O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :451.52Ivacaftor
CAS :<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Formule :C24H28N2O3Degré de pureté :99% - 99.98%Couleur et forme :SolidMasse moléculaire :392.49α-Thujone
CAS :<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23Fasudil dihydrochloride
CAS :<p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>Formule :C14H19Cl2N3O2SCouleur et forme :SolidMasse moléculaire :364.29Urolithin A
CAS :<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Formule :C13H8O4Degré de pureté :99.14% - 99.67%Couleur et forme :SolidMasse moléculaire :228.2Omipalisib
CAS :<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Formule :C25H17F2N5O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :505.5Vps34-IN-1
CAS :<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Formule :C21H24ClN7ODegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :425.91OSI-027
CAS :<p>OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.</p>Formule :C21H22N6O3Degré de pureté :97.42%Couleur et forme :SolidMasse moléculaire :406.44Nocodazole
CAS :<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Atorvastatin hemicalcium trihydrate
CAS :<p>Atorvastatin hemicalcium trihydrate, an oral HMG-CoA reductase inhibitor, lowers blood lipids and inhibits SV-SMC with IC50s: 0.39/2.39 μM.</p>Formule :C33H35FN2O5Ca·3H2OCouleur et forme :SolidMasse moléculaire :632.73Aliskiren hydrochloride
CAS :<p>Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia.</p>Formule :C30H54ClN3O6Couleur et forme :SolidMasse moléculaire :588.23Nesolicaftor
CAS :<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Formule :C18H18N4O4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :354.36SP600125
CAS :<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formule :C14H8N2ODegré de pureté :97.63% - 99.82%Couleur et forme :SolidMasse moléculaire :220.23XCT790
CAS :<p>XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).</p>Formule :C23H13F9N4O3SDegré de pureté :99% - 99.61%Couleur et forme :SolidMasse moléculaire :596.42Lithocholic acid
CAS :<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Formule :C24H40O3Degré de pureté :99.69% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57EIPA
CAS :<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Formule :C11H18ClN7ODegré de pureté :96.62% - 99.981%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :299.76SBI-0206965
CAS :<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formule :C21H21BrN4O5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :489.32Crenolanib
CAS :<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Formule :C26H29N5O2Degré de pureté :98.40% - 99.73%Couleur et forme :SolidMasse moléculaire :443.544,4'-Dimethoxychalcone
CAS :<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Formule :C17H16O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :268.31AG490
CAS :<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formule :C17H14N2O3Degré de pureté :98.6% - 99.39%Couleur et forme :Yellow SolidMasse moléculaire :294.3PF-06454589
CAS :<p>PF-06454589 is a potent inhibitor of LRRK2.</p>Formule :C14H16N6ODegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :284.32Lumacaftor
CAS :<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Formule :C24H18F2N2O5Degré de pureté :99.48% - 99.68%Couleur et forme :SolidMasse moléculaire :452.41ULK-101
CAS :<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Formule :C22H16F4N4OSDegré de pureté :97.55% - 99.94%Couleur et forme :SolidMasse moléculaire :460.45Ixazomib citrate
CAS :<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formule :C20H23BCl2N2O9Degré de pureté :98.37% - >99.99%Couleur et forme :SolidMasse moléculaire :517.12Regorafenib mesylate
CAS :<p>Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.</p>Formule :C22H19ClF4N4O6SCouleur et forme :SolidMasse moléculaire :578.92MLN9708 analogues
CAS :<p>MLN2238 inhibits 20S proteasome's β5 site (Ki50=0.93 nM, IC50=3.4 nM), active form of Ixazomib Citrate in solutions/plasma.</p>Formule :C20H23BCl2N2O9Degré de pureté :98.24% - 99.23%Couleur et forme :SolidMasse moléculaire :517.12Tepotinib hydrochloride(1 : x)
CAS :<p>Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14</p>Formule :C29H29ClN6O2Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :529.04Degrasyn
CAS :<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Formule :C19H18BrN3ODegré de pureté :98.32% - 99.98%Couleur et forme :SolidMasse moléculaire :384.27Trifluoperazine
CAS :<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Formule :C21H24F3N3SDegré de pureté :98.3% - 99.46%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :407.5E-64
CAS :<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Formule :C15H27N5O5Degré de pureté :98% - 99.95%Couleur et forme :White SolidMasse moléculaire :357.41Paeonol
CAS :<p>Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.</p>Formule :C9H10O3Degré de pureté :98.55% - 99.56%Couleur et forme :White To Beige Crystalline PowderMasse moléculaire :166.17Hoechst 33342 trihydrochloride
CAS :<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Formule :C27H31Cl3N6ODegré de pureté :98.73% - ≥98%Couleur et forme :SolidMasse moléculaire :561.93SN-38
CAS :<p>SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).</p>Formule :C22H20N2O5Degré de pureté :98% - 99.97%Couleur et forme :Light-Yellow SolidMasse moléculaire :392.4Vps34-PIK-III
CAS :<p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>Formule :C17H17N7Degré de pureté :98.39% - 98.43%Couleur et forme :SolidMasse moléculaire :319.36UM-164
CAS :<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formule :C30H31F3N8O3SDegré de pureté :98.72% - 99.52%Couleur et forme :SolidMasse moléculaire :640.68LYS01
CAS :<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Formule :C23H23Cl2N5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :440.37Rottlerin
CAS :<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54Sertaconazole nitrate
CAS :<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formule :C20H15Cl3N2OS·HNO3Degré de pureté :98.66% - 99.65%Couleur et forme :SolidMasse moléculaire :500.78Meglutol
CAS :<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Formule :C6H10O5Degré de pureté :99.73% - 99.94%Couleur et forme :SolidMasse moléculaire :162.14Rosiglitazone hydrochloride
CAS :<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formule :C18H19N3O3S·HClDegré de pureté :99.63% - 99.79%Couleur et forme :SolidMasse moléculaire :393.89Olaparib
CAS :<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Formule :C24H23FN4O3Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :434.46Azithromycin
CAS :<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Formule :C38H72N2O12Degré de pureté :99.9% - 99.97%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :748.98MRT68921 dihydrochloride
CAS :<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Formule :C25H36Cl2N6ODegré de pureté :98.91% - 99.92%Couleur et forme :SolidMasse moléculaire :507.499MG-132
CAS :<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62Pexmetinib
CAS :<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formule :C31H33FN6O3Degré de pureté :99.07% - 99.66%Couleur et forme :SolidMasse moléculaire :556.63Clinofibrate
CAS :<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Formule :C28H36O6Degré de pureté :>99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :468.58Venetoclax
CAS :<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Formule :C45H50ClN7O7SDegré de pureté :98.00% - 99.97%Couleur et forme :SolidMasse moléculaire :868.44Sevelamer hydrochloride
CAS :<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Formule :(C3H7N·C3H5ClO·HCl)xDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.08Idelalisib
CAS :<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42Cucurbitacin B
CAS :<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formule :C32H46O8Degré de pureté :97.1% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7PATULIN
CAS :<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Formule :C7H6O4Degré de pureté :99.91% - 99.98%Couleur et forme :Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMasse moléculaire :154.12
