Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1424 produits trouvés pour "Autophagie"
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sbp-7455
CAS :<p>SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.</p>Formule :C16H17F3N4O2Degré de pureté :97.90% - 99.842%Couleur et forme :SolidMasse moléculaire :354.33Kaempferol
CAS :<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Formule :C15H10O6Degré de pureté :98% - 99.41%Couleur et forme :Yellow Needles From Alcohol And Water SolidMasse moléculaire :286.24Amsacrine hydrochloride
CAS :<p>Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.</p>Formule :C21H20ClN3O3SDegré de pureté :99.05% - 99.92%Couleur et forme :SolidMasse moléculaire :429.92Typhaneoside
CAS :<p>Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.</p>Formule :C34H42O20Degré de pureté :98.92% - 99.95%Couleur et forme :SolidMasse moléculaire :770.69DPN
CAS :<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Formule :C15H13NO2Degré de pureté :99.01%Couleur et forme :Off-White SolidMasse moléculaire :239.27Pantoprazole
CAS :<p>Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux</p>Formule :C16H15F2N3O4SDegré de pureté :99.28% - 99.63%Couleur et forme :Almost White SolidMasse moléculaire :383.37AS-605240
CAS :<p>AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).</p>Formule :C12H7N3O2SDegré de pureté :97% - 99.91%Couleur et forme :SolidMasse moléculaire :257.27Nutlin-3a
CAS :<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Formule :C30H30Cl2N4O4Degré de pureté :95.62% - 99.71%Couleur et forme :SolidMasse moléculaire :581.49FIPI
CAS :<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Formule :C23H24FN5O2Degré de pureté :97.21% - 98.68%Couleur et forme :SolidMasse moléculaire :421.47Sirtinol
CAS :<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Quercitrin
CAS :<p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>Formule :C21H20O11Degré de pureté :98.89% - 99.66%Couleur et forme :Yellow Crystals From Dil Methanol Or Ethanol SolidMasse moléculaire :448.38Embelin
CAS :<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39GNE-9605
CAS :<p>GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).</p>Formule :C17H20ClF4N7ODegré de pureté :98.55% - 98.75%Couleur et forme :SolidMasse moléculaire :449.83PX-478
CAS :<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Formule :C13H20Cl4N2O3Degré de pureté :97% - 99.79%Couleur et forme :SolidMasse moléculaire :394.12Rotenone
CAS :<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Quisinostat dihydrochloride
CAS :<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Formule :C21H28Cl2N6O2Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :467.39Mdivi-1
CAS :<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formule :C15H10Cl2N2O2SDegré de pureté :96.57% - 99.23%Couleur et forme :SolidMasse moléculaire :353.22SMER28
CAS :<p>SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.</p>Formule :C11H10BrN3Degré de pureté :99.94% - >99.99%Couleur et forme :SolidMasse moléculaire :264.12Rasagiline Mesylate
CAS :<p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>Formule :C13H17NO3SDegré de pureté :99.33%Couleur et forme :White PowderMasse moléculaire :267.34LC3-mHTT-IN-AN1
CAS :<p>LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.</p>Formule :C15H9Br2NO3Degré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :411.04Alisertib
CAS :<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Formule :C27H20ClFN4O4Degré de pureté :98.31% - >99.99%Couleur et forme :SolidMasse moléculaire :518.92Afatinib
CAS :<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formule :C24H25ClFN5O3Degré de pureté :98.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Tubastatin A
CAS :<p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>Formule :C20H21N3O2Degré de pureté :97.22% - 99.51%Couleur et forme :SolidMasse moléculaire :335.4Mycro 3
CAS :<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Formule :C24H17ClF2N6O4Degré de pureté :99.51% - 99.61%Couleur et forme :SolidMasse moléculaire :526.88Neferine
CAS :<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Formule :C38H44N2O6Degré de pureté :98.81% - 99.65%Couleur et forme :SolidMasse moléculaire :624.773-Bromopyruvic acid
CAS :<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Formule :C3H3BrO3Degré de pureté :95% - 99.644%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :166.96MK-2206 dihydrochloride
CAS :<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formule :C25H23Cl2N5ODegré de pureté :99.228% - 99.94%Couleur et forme :SolidMasse moléculaire :480.39Diosgenin glucoside
CAS :<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formule :C33H52O8Degré de pureté :97.17% - 99.44%Couleur et forme :SolidMasse moléculaire :576.76Fangchinoline
CAS :<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Formule :C37H40N2O6Degré de pureté :99.86% - >99.99%Couleur et forme :SolidMasse moléculaire :608.72Schisandrol B
CAS :<p>Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.</p>Formule :C23H28O7Degré de pureté :99.14% - 99.95%Couleur et forme :SolidMasse moléculaire :416.46AZD 6482
CAS :<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.45Brefeldin A
CAS :<p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>Formule :C16H24O4Degré de pureté :96.45% - 99.89%Couleur et forme :White SolidMasse moléculaire :280.36Dioscin
CAS :<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Formule :C45H72O16Degré de pureté :99.85% - 99.87%Couleur et forme :SolidMasse moléculaire :869.04GLPG1837
CAS :<p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>Formule :C16H20N4O3SDegré de pureté :99.64% - 99.91%Couleur et forme :SolidMasse moléculaire :348.42ABT-737
CAS :<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formule :C42H45ClN6O5S2Degré de pureté :98.15% - >99.99%Couleur et forme :SolidMasse moléculaire :813.43Neflamapimod
CAS :<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Formule :C19H9Cl2F2N3OSDegré de pureté :97.88% - 99.75%Couleur et forme :SolidMasse moléculaire :436.26Turofexorate Isopropyl
CAS :<p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>Formule :C25H24F2N2O3Degré de pureté :98.55% - 99.73%Couleur et forme :SolidMasse moléculaire :438.47Calcimycin
CAS :<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Formule :C29H37N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.62Vandetanib
CAS :<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35SGI-1776
CAS :<p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>Formule :C20H22F3N5ODegré de pureté :99.3% - >99.99%Couleur et forme :SolidMasse moléculaire :405.42Carbamazepine
CAS :<p>Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.</p>Formule :C15H12N2ODegré de pureté :99.78% - 99.79%Couleur et forme :SolidMasse moléculaire :236.27Milciclib
CAS :<p>Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.</p>Formule :C25H32N8ODegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :460.57STF-62247
CAS :<p>STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.</p>Formule :C15H13N3SDegré de pureté :99.6% - 99.67%Couleur et forme :SolidMasse moléculaire :267.35Fenretinide
CAS :<p>Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.</p>Formule :C26H33NO2Degré de pureté :98% - 99.68%Couleur et forme :Yellow PowderMasse moléculaire :391.55Isoalantolactone
CAS :<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.32CD437
CAS :<p>CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.</p>Formule :C27H26O3Degré de pureté :98.92% - 99.63%Couleur et forme :SolidMasse moléculaire :398.49Zoledronic acid monohydrate
CAS :<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Formule :C5H12N2O8P2Degré de pureté :99.91%Couleur et forme :White To Off-White PowderMasse moléculaire :290.1Betulinic acid
CAS :<p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>Formule :C30H48O3Degré de pureté :99.12% - 99.7%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7ISOGINKGETIN
CAS :<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formule :C32H22O10Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :566.51FERULIC ACID METHYL ESTER
CAS :<p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>Formule :C11H12O4Degré de pureté :99.66% - 99.95%Couleur et forme :SolidMasse moléculaire :208.21Wogonoside
CAS :<p>Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.</p>Formule :C22H20O11Degré de pureté :98.24% - >99.99%Couleur et forme :SolidMasse moléculaire :460.39Oroxin B
CAS :<p>Oroxin B (Hypocretin-2) has antioxidant activity.</p>Formule :C27H30O15Degré de pureté :98.22% - 99.81%Couleur et forme :SolidMasse moléculaire :594.52Topotecan
CAS :<p>Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.</p>Formule :C23H23N3O5Degré de pureté :96.14% - 98.23%Couleur et forme :Light Yellow Needle Crystal Or Crystalline PowderMasse moléculaire :421.45Obatoclax Mesylate
CAS :<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>Formule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49LRRK2-IN-1
CAS :<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Formule :C31H38N8O3Degré de pureté :98% - 98.82%Couleur et forme :SolidMasse moléculaire :570.69Cabazitaxel
<p>Cabazitaxel (XRP6258) is a taxane used for castration-resistant metastatic prostate cancer post-docetaxel failure.</p>Formule :C45H57NO14Degré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :835.93Daphnetin
CAS :<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14H-89 dihydrochloride
CAS :<p>H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).</p>Formule :C20H20BrN3O2S·2HClDegré de pureté :98.22% - >99.99%Couleur et forme :SolidMasse moléculaire :519.28PD98059
CAS :<p>PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.</p>Formule :C16H13NO3Degré de pureté :98.63% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :267.28ML327
CAS :<p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>Formule :C19H18N4O4Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :366.37Chloroquine
CAS :<p>Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.</p>Formule :C18H26ClN3Degré de pureté :99.5% - 99.98%Couleur et forme :White To Slightly Yellow Crystalline Powder SolidMasse moléculaire :319.87Samotolisib
CAS :<p>Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.</p>Formule :C23H26N4O3Degré de pureté :98.41% - 99.69%Couleur et forme :SolidMasse moléculaire :406.48Sitagliptin phosphate
CAS :<p>Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.</p>Formule :C16H18F6N5O5PDegré de pureté :99.72% - 99.91%Couleur et forme :White SolidMasse moléculaire :505.31A-484954
CAS :<p>A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.</p>Formule :C13H15N5O3Degré de pureté :97.47% - 99.86%Couleur et forme :SolidMasse moléculaire :289.29KN-92 phosphate
CAS :<p>KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.</p>Formule :C24H28ClN2O7PSDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :554.98Autophinib
CAS :<p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>Formule :C14H11ClN6O3Degré de pureté :99.25% - 99.41%Couleur et forme :SolidMasse moléculaire :346.73Salvigenin
CAS :<p>Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.</p>Formule :C18H16O6Degré de pureté :99.17% - 99.78%Couleur et forme :SolidMasse moléculaire :328.32Wortmannin
CAS :<p>Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.</p>Formule :C23H24O8Degré de pureté :95.84% - 99.76%Couleur et forme :White SolidMasse moléculaire :428.43Leonurine
CAS :<p>Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.</p>Formule :C14H21N3O5Degré de pureté :98.55%Couleur et forme :White Crystalline PowderMasse moléculaire :311.33GW786034B
CAS :<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98PF-04691502
CAS :<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48Losmapimod
CAS :<p>Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).</p>Formule :C22H26FN3O2Degré de pureté :98.35% - 99.89%Couleur et forme :SolidMasse moléculaire :383.46DC661
CAS :<p>DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.</p>Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Linifanib
CAS :<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Indophagolin
CAS :<p>Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.</p>Formule :C19H15BrClF3N2O3SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :523.75Saracatinib
CAS :<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03Pamapimod
CAS :<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Formule :C19H20F2N4O4Degré de pureté :99.52% - 99.99%Couleur et forme :SolidMasse moléculaire :406.38Crizotinib hydrochloride
CAS :<p>Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)</p>Formule :C21H23Cl3FN5ODegré de pureté :98.73% - 98.87%Couleur et forme :SolidMasse moléculaire :486.8Danusertib
CAS :<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.553-Methyladenine
CAS :<p>3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).</p>Formule :C6H7N5Degré de pureté :98.02% - 99.65%Couleur et forme :SolidMasse moléculaire :149.15WYC-209
CAS :<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Formule :C20H20N2O3SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :368.45Salirasib
CAS :<p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54Afatinib Dimaleate
CAS :<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formule :C32H33ClFN5O11Degré de pureté :98.11% - 99.87%Couleur et forme :SolidMasse moléculaire :718.08PFK-015
CAS :<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Formule :C17H12N2ODegré de pureté :99.7% - 99.85%Couleur et forme :SolidMasse moléculaire :260.29TA-02
CAS :<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Formule :C20H13F2N3Degré de pureté :99.35% - 99.79%Couleur et forme :SolidMasse moléculaire :333.33Sepantronium bromide
CAS :<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formule :C20H19BrN4O3Degré de pureté :99.68% - 99.85%Couleur et forme :SolidMasse moléculaire :443.26LY294002
CAS :<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Pogostone
CAS :<p>Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.</p>Formule :C12H16O4Degré de pureté :98.46% - 99.03%Couleur et forme :SolidMasse moléculaire :224.25PFI-1
CAS :<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.393'-Hydroxypterostilbene
CAS :<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3BIIB021
CAS :<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Formule :C14H15ClN6ODegré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :318.76Andrographolide
CAS :<p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>Formule :C20H30O5Degré de pureté :99.39% - 99.97%Couleur et forme :PowderMasse moléculaire :350.45Sapanisertib
CAS :<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Formule :C15H15N7ODegré de pureté :99.19% - >99.99%Couleur et forme :SolidMasse moléculaire :309.33BIX-01294 trihydrochloride
CAS :<p>BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.</p>Formule :C28H38N6O2·3HClDegré de pureté :99.41% - 99.95%Couleur et forme :SolidMasse moléculaire :600.02yangonin
CAS :<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Torkinib
CAS :<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Formule :C16H16N6ODegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :308.34CCT007093
CAS :<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Formule :C15H12OS2Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :272.39Resatorvid
CAS :<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formule :C15H17ClFNO4SDegré de pureté :99.31% - >99.99%Couleur et forme :SolidMasse moléculaire :361.82Fulvestrant
CAS :<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>Formule :C32H47F5O3SDegré de pureté :99.1% - >99.99%Couleur et forme :White PowderMasse moléculaire :606.77Flavopiridol hydrochloride
CAS :<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Formule :C21H21Cl2NO5Degré de pureté :98.87% - 99.88%Couleur et forme :SolidMasse moléculaire :438.3Orthanilamide
CAS :<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formule :C6H8N2O2SDegré de pureté :99.72% - 99.96%Couleur et forme :White To Pale Cream Crystalline Powder Or CrystalsMasse moléculaire :172.2AGN 193109
CAS :<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Formule :C28H24O2Degré de pureté :99.87% - 99.89%Couleur et forme :SolidMasse moléculaire :392.49MPP+ iodide
CAS :<p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>Formule :C12H12INDegré de pureté :99.49% - 99.96%Couleur et forme :SolidMasse moléculaire :297.13Telaglenastat
CAS :<p>Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.</p>Formule :C26H24F3N7O3SDegré de pureté :97.57% - 99.89%Couleur et forme :SolidMasse moléculaire :571.57GSK2578215A
CAS :<p>GSK2578215A is a potent and selective LRRK2 kinase inhibitor.</p>Formule :C24H18FN3O2Degré de pureté :99.57% - 99.94%Couleur et forme :SolidMasse moléculaire :399.42Imatinib
CAS :<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Formule :C29H31N7ODegré de pureté :99.42% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Sinomenine
CAS :<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formule :C19H23NO4Degré de pureté :99.02% - 99.73%Couleur et forme :White PowderMasse moléculaire :329.39Demethoxycurcumin
CAS :<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Formule :C20H18O5Degré de pureté :94.54% - 99.86%Couleur et forme :SolidMasse moléculaire :338.35Ginkgolide K
CAS :<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Formule :C20H22O9Degré de pureté :99.44% - 99.72%Couleur et forme :SolidMasse moléculaire :406.38Aloperine
CAS :<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formule :C15H24N2Degré de pureté :98% - 99.88%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :232.36Arglabin
CAS :<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Formule :C15H18O3Degré de pureté :98.97% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Bilobalide
CAS :<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formule :C15H18O8Degré de pureté :98.81% - 99.92%Couleur et forme :White SolidMasse moléculaire :326.3Clematichinenoside AR
CAS :<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Formule :C82H134O43Degré de pureté :99.04% - 99.69%Couleur et forme :SolidMasse moléculaire :1807.92Apocynin
CAS :<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Formule :C9H10O3Degré de pureté :99.71% - 99.98%Couleur et forme :Yellowish To Brown PowderMasse moléculaire :166.17HA15
CAS :<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Formule :C23H22N4O3S2Degré de pureté :99.77% - 99.86%Couleur et forme :SolidMasse moléculaire :466.58Dimethyl fumarate
CAS :<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formule :C6H8O4Degré de pureté :90.51% - >99.99%Couleur et forme :White To Off-White Powder White Crystalline PowderMasse moléculaire :144.13ISRIB (trans-isomer)
CAS :<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Formule :C22H24Cl2N2O4Degré de pureté :97.86% - 99.27%Couleur et forme :SolidMasse moléculaire :451.34Salubrinal
CAS :<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formule :C21H17Cl3N4OSDegré de pureté :97.25% - >99.99%Couleur et forme :SolidMasse moléculaire :479.81Binimetinib
CAS :<p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C17H15BrF2N4O3Degré de pureté :98.03% - >99.99%Couleur et forme :SolidMasse moléculaire :441.23Reparixin
CAS :<p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>Formule :C14H21NO3SDegré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :283.39Daurisoline
CAS :<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formule :C37H42N2O6Degré de pureté :98% - 99.96%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74Bigelovin
CAS :<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formule :C17H20O5Degré de pureté :99.61% - 99.72%Couleur et forme :SolidMasse moléculaire :304.34Britannin
CAS :<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formule :C19H26O7Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :366.41Verteporfin
CAS :<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Ralimetinib dimesylate
CAS :<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formule :C24H29FN6·2CH4O3SDegré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :612.74Hydroxyprogesterone caproate
CAS :<p>Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.</p>Formule :C27H40O4Degré de pureté :99.70%Couleur et forme :White Or Almost White Crystalline PowerMasse moléculaire :428.60Tizoxanide
CAS :<p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Bardoxolone Methyl
CAS :<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.69BMS-582949 hydrochloride
CAS :<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Formule :C22H27ClN6O2Degré de pureté :97.57% - 98.75%Couleur et forme :SolidMasse moléculaire :442.95Tazarotene
CAS :<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Formule :C21H21NO2SDegré de pureté :97.01% - 99.14%Couleur et forme :White SolidMasse moléculaire :351.46Deguelin
CAS :<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Formule :C23H22O6Degré de pureté :96.39% - 99.29%Couleur et forme :SolidMasse moléculaire :394.42BIA 10-2474
CAS :<p>BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.</p>Formule :C16H20N4O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :300.36Pirarubicin
CAS :<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formule :C32H37NO12Degré de pureté :97.80% - 99.15%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64kaempferide
CAS :<p>kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.</p>Formule :C16H12O6Degré de pureté :98.31% - 99.66%Couleur et forme :SolidMasse moléculaire :300.26SR12813
CAS :<p>SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.</p>Formule :C24H42O7P2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :504.53Meloxicam
CAS :<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Formule :C14H13N3O4S2Degré de pureté :97.09% - 99.60%Couleur et forme :Light Yellow SolidMasse moléculaire :351.40740 Y-P
CAS :<p>740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!</p>Formule :C141H222N43O39PS3Degré de pureté :98.3% - 99.87%Couleur et forme :SolidMasse moléculaire :3270.7Fluvastatin
CAS :<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Formule :C24H26FNO4Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :411.47ML 145
CAS :<p>ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)</p>Formule :C24H22N2O5S2Degré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :482.57SB 203580 hydrochloride
CAS :<p>SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.</p>Formule :C21H17ClFN3OSDegré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :413.9mTOR inhibitor-8
CAS :<p>mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.</p>Formule :C24H19ClN4OSDegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :446.95Ketanserin tartrate
CAS :<p>Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.</p>Formule :C26H28FN3O9Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :545.51Ezetimibe ketone
CAS :<p>Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.</p>Formule :C24H19F2NO3Degré de pureté :99.32%Couleur et forme :White Crystalline SolidMasse moléculaire :407.41Doxorubicin
CAS :<p>Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.</p>Formule :C27H29NO11Degré de pureté :99.31%Couleur et forme :Red Crystalline Solid SolidMasse moléculaire :543.52Chenodeoxycholic Acid sodium salt
CAS :<p>Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.</p>Formule :C24H39NaO4Degré de pureté :99.68% - 99.72%Couleur et forme :SolidMasse moléculaire :414.55H-89
CAS :<p>H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.</p>Formule :C20H20BrN3O2SDegré de pureté :98.06%Couleur et forme :Off-White PowderMasse moléculaire :446.36Sitagliptin phosphate monohydrate
CAS :<p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>Formule :C16H15F6N5O·H3PO4·H2ODegré de pureté :99.85% - 99.98%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :523.33Latrepirdine dihydrochloride
CAS :<p>Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.</p>Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.37Rosuvastatin-d6 Sodium Salt
CAS :<p>Rosuvastatin-d6 Sodium Salt is a deuterated compound of Rosuvastatin Sodium Salt. Rosuvastatin Sodium Salt has a CAS number of 1007871-86-4.</p>Formule :C22H21D6FN3NaO6SCouleur et forme :SolidMasse moléculaire :509.56Irinotecan-d10 Hydrochloride
CAS :<p>Irinotecan-d10 Hydrochloride is a deuterated compound of Irinotecan Hydrochloride. Irinotecan Hydrochloride has a CAS number of 100286-90-6. Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. Because ongoing DNA synthesis is necessary for irinotecan to exert its cytotoxic effects, it is classified as an S-phase-specific agent.</p>Formule :C33H29D10ClN4O6Couleur et forme :SolidMasse moléculaire :633.20Tigecycline-d9
CAS :<p>Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.</p>Formule :C29H30D9N5O8Couleur et forme :SolidMasse moléculaire :594.70Lovastatin-d3
CAS :<p>Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.</p>Formule :C24H33D3O5Couleur et forme :SolidMasse moléculaire :407.56VX-702
CAS :<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formule :C19H12F4N4O2Degré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :404.32MK-5108
CAS :<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.94Bexarotene
CAS :<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Formule :C24H28O2Degré de pureté :99% - 99.65%Couleur et forme :White SolidMasse moléculaire :348.48Alisol A
CAS :<p>Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.</p>Formule :C30H50O5Degré de pureté :99.77% - 99.94%Couleur et forme :SolidMasse moléculaire :490.71Dehydrocorydaline nitrate
CAS :<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formule :C22H24N2O7Degré de pureté :99.79% - 99.92%Couleur et forme :SolidMasse moléculaire :428.44Atorvastatin
CAS :<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formule :C33H35FN2O5Degré de pureté :99.37% - 99.69%Couleur et forme :SolidMasse moléculaire :558.64BGT226 maleate
CAS :<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Formule :C28H25F3N6O2·C4H4O4Degré de pureté :97.75% - 98.78%Couleur et forme :SolidMasse moléculaire :650.6Brivanib (alaninate)
CAS :<p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>Formule :C22H24FN5O4Degré de pureté :99.46% - 99.66%Couleur et forme :SolidMasse moléculaire :441.46Rac-Efavirenz
CAS :<p>Rac-Efavirenz is a non stereospecific structure of Efavirenz.</p>Formule :C14H9ClF3NO2Couleur et forme :SolidMasse moléculaire :315.67Chloroquine dihydrochloride
CAS :<p>Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.</p>Formule :C18H27Cl2N3Couleur et forme :SolidMasse moléculaire :356.33Metyrapone Tartrate
CAS :<p>Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.</p>Formule :C22H26N2O13Couleur et forme :SolidMasse moléculaire :526.45Euchrysine 3RX
CAS :<p>Euchrysine 3RX is an agent of bioactive chemicals.</p>Formule :C20H26BrCl2N3ODegré de pureté :98%Couleur et forme :Brown PowderMasse moléculaire :475.25Pravastatin
CAS :<p>Pravastatin reduces lipoproteins by blocking HMG-CoA reductase and VLDL synthesis.</p>Formule :C23H36O7Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :424.53Resveratrol analog 2
CAS :<p>Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.</p>Formule :C16H13FO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :272.27YT-8-8
CAS :<p>YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.</p>Formule :C18H23FN2O2Couleur et forme :SolidMasse moléculaire :318.39Erlotinib mesylate
CAS :<p>Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.</p>Formule :C23H27N3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.54Esmolol hydrochloride
CAS :<p>Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.</p>Formule :C16H25NO4·HClDegré de pureté :98.72% - 99.48%Couleur et forme :White SolidMasse moléculaire :331.15TAMRA alkyne, 6-isomer
CAS :<p>TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.</p>Formule :C28H25N3O4Couleur et forme :SolidMasse moléculaire :467.52Gavilimomab
CAS :<p>Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).</p>Degré de pureté :95%Couleur et forme :LiquidPBA-1105
CAS :<p>PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.</p>Formule :C39H48N2O6Couleur et forme :SolidMasse moléculaire :640.81Seriniquinone
CAS :<p>Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.</p>Formule :C20H8O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.34Paroxetine hydrochloride hemihydrate
CAS :<p>Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).</p>Formule :C38H44Cl2F2N2O7Degré de pureté :99.949%Couleur et forme :SolidMasse moléculaire :749.67SU11274
CAS :<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Formule :C28H30ClN5O4SDegré de pureté :98.62% - 99.53%Couleur et forme :Orange PowderMasse moléculaire :568.09Metofenazate
CAS :<p>Metofenazate is an selective inhibitor of calmodulin .</p>Formule :C31H36ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :598.15CXCR3 Antagonist 6c
CAS :<p>CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.</p>Formule :C30H32Cl3N5O3Couleur et forme :SolidMasse moléculaire :616.97Momelotinib Mesylate
CAS :<p>Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.</p>Formule :C24H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.57MF-095
CAS :<p>MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.</p>Formule :C27H31N3O4SCouleur et forme :SolidMasse moléculaire :493.62(3S,5R)-Rosuvastatin
CAS :<p>(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).</p>Formule :C22H28FN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.54p38 MAPK-IN-2
CAS :<p>p38 MAPK-IN-2 is an inhibitor of p38 kinase.</p>Formule :C20H19ClFN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.85HF50731
CAS :<p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>Formule :C26H46N4Couleur et forme :SolidMasse moléculaire :414.67ATG7-IN-2
CAS :<p>ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.</p>Formule :C11H16N6O7SCouleur et forme :SolidMasse moléculaire :376.35GLPG2451
CAS :<p>GLPG2451 potentiates F508del CFTR at low temp (EC50: 11.1 nM), aiding cystic fibrosis treatment.</p>Formule :C16H16F3N3O5SCouleur et forme :SolidMasse moléculaire :419.38SMER18
CAS :<p>SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.</p>Formule :C16H14ClNO2Degré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :287.74Omeprazole Sodium
CAS :<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4Ivacaftor hydrate
CAS :<p>Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.</p>Formule :C24H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.514CXCR4 antagonist 5
CAS :<p>CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.</p>Formule :C21H30N6Couleur et forme :SolidMasse moléculaire :366.5Poloppin
CAS :<p>Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.</p>Formule :C20H15BrF3NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.24PF-06455943
CAS :<p>PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.</p>Formule :C17H14FN5OCouleur et forme :SolidMasse moléculaire :323.32Ivacaftor benzenesulfonate
CAS :<p>Ivacaftor benzenesulfonate used for cystic fibrosis treatment. is an orally bioavailable CFTR potentiator.</p>Formule :C30H34N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.67eIF4A3-IN-2
CAS :<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Formule :C25H19Br2ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71Ralimetinib
CAS :<p>Ralimetinib blocks MK2 phosphorylation at Thr334 without affecting p38α MAPK or JNK. It is an ATP-competitive inhibitor of p38 MAPK α/β (IC50 5.3/3.2 nM).</p>Formule :C24H29FN6Degré de pureté :99.16% - 99.21%Couleur et forme :SolidMasse moléculaire :420.53PF-06371900
CAS :<p>PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).</p>Formule :C17H16N6O2SCouleur et forme :SolidMasse moléculaire :368.41Lamotrigine isethionate
CAS :<p>Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.</p>Formule :C11H13Cl2N5O4SCouleur et forme :SolidMasse moléculaire :382.22SR 3677 dihydrochloride
CAS :<p>Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).</p>Formule :C22H26Cl2N4O4Couleur et forme :SolidMasse moléculaire :481.37NSC 33994
CAS :<p>NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.</p>Formule :C28H42N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.65CXCR4 modulator-2
CAS :<p>CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.</p>Formule :C21H32N8O2Couleur et forme :SolidMasse moléculaire :428.53SMYD3-IN-2
<p>SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.</p>Formule :C26H21BrN2O4Couleur et forme :SolidMasse moléculaire :505.36Quinacrine analog 34
CAS :<p>Quinacrine: anti-protozoal, autophagy inhibitor (toxic at 2.5 μM). Analog 34 less toxic (LD50 = 27 μM), raises LC3-II protein, deacidifies lysosomes.</p>Formule :C20H27ClN4Couleur et forme :SolidMasse moléculaire :358.91
