Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1427 produits trouvés pour "Autophagie"
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Reserpine
CAS :<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68Fluvastatin sodium
CAS :<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formule :C24H25FNNaO4Degré de pureté :98.54% - 99.56%Couleur et forme :Light Yellow Solid PowderMasse moléculaire :433.45Pterostilbene
CAS :<p>Pterostilbene is extracted from Pterocarpus indicus.</p>Formule :C16H16O3Degré de pureté :99.20%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :256.33,3'-Diindolylmethane
CAS :<p>3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.</p>Formule :C17H14N2Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :246.31Raloxifene hydrochloride
CAS :<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Formule :C28H28ClNO4SDegré de pureté :98% - 99.97%Couleur et forme :Light Yellow SolidMasse moléculaire :510.044Berberine chloride
CAS :<p>Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.</p>Formule :C20H18ClNO4Degré de pureté :99.47% - 99.93%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :371.8Indazole
CAS :<p>Indazole, a heterocyclic compound, offers diverse biological activities.</p>Formule :C7H6N2Degré de pureté :99.59% - 99.85%Couleur et forme :White Or Beige Crystalline PowderMasse moléculaire :118.14Vinorelbine
CAS :<p>Vinorelbine, a semisynthetic vinca alkaloid, inhibits tubulin, blocking mitotic spindle formation and tumor growth.</p>Formule :C45H54N4O8Degré de pureté :98.62% - 99.99%Couleur et forme :SolidMasse moléculaire :778.93Metyrapone
CAS :<p>Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.</p>Formule :C14H14N2ODegré de pureté :99.03% - ≥95%Couleur et forme :Crystals From Ether & Pentane SolidMasse moléculaire :226.27Telmisartan
CAS :<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Formule :C33H30N4O2Degré de pureté :99.88% - 99.97%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :514.62Retinoic acid
CAS :<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Formule :C20H28O2Degré de pureté :97.21% - 99.6%Couleur et forme :Yellow-Orange PowderMasse moléculaire :300.44Myricetin
CAS :<p>Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.</p>Formule :C15H10O8Degré de pureté :97.92% - 99.85%Couleur et forme :Yellow Needles From Dilute Alcohol SolidMasse moléculaire :318.24Dexamethasone
CAS :<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Formule :C22H29FO5Degré de pureté :98% - 99.91%Couleur et forme :Crystals From Ether (Ntp 1992)Masse moléculaire :392.46Phenformin hydrochloride
CAS :<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formule :C10H16ClN5Degré de pureté :97.11% - 99.80%Couleur et forme :Lactic AcidosisMasse moléculaire :241.72Mevastatin
CAS :<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formule :C23H34O5Degré de pureté :99.12%Couleur et forme :White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :390.51Cytarabine
CAS :<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Erlotinib
CAS :<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formule :C22H23N3O4Degré de pureté :98.19% - 99.98%Couleur et forme :White To Off-White PowderMasse moléculaire :393.44Sophocarpine monohydrate
CAS :<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formule :C15H22N2ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :246.35AZD7624
CAS :<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formule :C27H30FN5O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :491.56Oxaliplatin
CAS :<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formule :C8H14N2O4PtDegré de pureté :97% - 99.93%Couleur et forme :SolidMasse moléculaire :397.29Thalidomide
CAS :<p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>Formule :C13H10N2O4Degré de pureté :98.88% - 99.88%Couleur et forme :White SolidMasse moléculaire :258.23Lapatinib Ditosylate
CAS :<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :99.41%Couleur et forme :Yellow SolidMasse moléculaire :925.46Doxazosin mesylate
CAS :<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Formule :C24H29N5O8SDegré de pureté :99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :547.58Vancomycin hydrochloride
CAS :<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Formule :C66H76Cl3N9O24Degré de pureté :97.20% - 99.19%Couleur et forme :Off White PowderMasse moléculaire :1485.71ZX-29
CAS :<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Formule :C23H28ClN7O3SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :518.03LG-100064
CAS :<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Formule :C23H26O3Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :350.45Pictilisib dimethanesulfonate
CAS :<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Formule :C25H35N7O9S4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :705.85Sulfadoxine
CAS :<p>Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial</p>Formule :C12H14N4O4SDegré de pureté :99.67%Couleur et forme :White Or White Crystalline PowderMasse moléculaire :310.33Lomustine
CAS :<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Formule :C9H16ClN3O2Degré de pureté :98.36% - 99.44%Couleur et forme :Solid SolidMasse moléculaire :233.7Trimetazidine dihydrochloride
CAS :<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Formule :C14H24Cl2N2O3Degré de pureté :99.58%Couleur et forme :Crystalline SolidMasse moléculaire :339.258Crustecdysone
CAS :<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formule :C27H44O7Degré de pureté :99.06% - 99.67%Couleur et forme :Canary Yellow Fine PowderMasse moléculaire :480.63Vitamin B3-d4
CAS :<p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>Formule :C6HD4NO2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :127.13Doxorubicin hydrochloride
CAS :<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Formule :C27H29NO11·HClDegré de pureté :98% - 99.52%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.99Oxidopamine hydrobromide
CAS :<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formule :C8H12BrNO3Degré de pureté :98.22% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09NBDHEX
CAS :<p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>Formule :C12H15N3O4SDegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :297.33Silmitasertib sodium salt
CAS :<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Formule :C19H11ClN3NaO2Degré de pureté :99.49% - 99.62%Couleur et forme :SolidMasse moléculaire :371.75Irinotecan Hydrochloride
CAS :<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formule :C33H39ClN4O6Degré de pureté :98% - 99.94%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :623.14Ketanserin
CAS :<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Paclitaxel
CAS :<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formule :C47H51NO14Degré de pureté :98% - 99.92%Couleur et forme :White PowderMasse moléculaire :853.91Hydroxyurea
CAS :<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formule :CH4N2O2Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :76.05Glibenclamide
CAS :<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00Deferoxamine Mesylate
CAS :<p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>Formule :C26H52N6O11SDegré de pureté :94.68% - 99.8%Couleur et forme :SolidMasse moléculaire :656.79Rhein
CAS :<p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>Formule :C15H8O6Degré de pureté :99.04%Couleur et forme :Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Masse moléculaire :284.22MLi-2
CAS :<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Formule :C21H25N5O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :379.46Spironolactone
CAS :<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formule :C24H32O4SDegré de pureté :99.87%Couleur et forme :White PowderMasse moléculaire :416.57BIX 02565
CAS :<p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>Formule :C26H30N6O2Degré de pureté :97.44% - 99.7%Couleur et forme :SolidMasse moléculaire :458.56Chenodeoxycholic acid
CAS :<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formule :C24H40O4Degré de pureté :99.70% - 99.93%Couleur et forme :White - Almost White Solid PowderMasse moléculaire :392.57Salicylic acid
CAS :<p>Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.</p>Formule :C7H6O3Degré de pureté :98.04% - 98.83%Couleur et forme :White Solid PowderMasse moléculaire :138.12Sorafenib tosylate
CAS :<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :99.24% - 99.94%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :637.03Trifluoperazine dihydrochloride
CAS :Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formule :C21H26Cl2F3N3SDegré de pureté :99.57% - 99.96%Couleur et forme :Cream Fine PowderMasse moléculaire :480.43
