Récepteur de l'histamine
Les récepteurs de l'histamine sont des GPCR qui médiatisent les effets de l'histamine, une amine biogène impliquée dans les réponses immunitaires, la sécrétion d'acide gastrique et la neurotransmission. Il existe quatre sous-types de récepteurs de l'histamine (H1, H2, H3 et H4), chacun jouant des rôles distincts dans les réactions allergiques, la fonction gastrique et l'activité du système nerveux central. Les antagonistes des récepteurs de l'histamine sont largement utilisés dans le traitement des allergies, des ulcères gastriques et du mal des transports. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de récepteurs de l'histamine de haute qualité pour soutenir vos recherches en immunologie, gastroentérologie et neuropharmacologie.
358 produits trouvés pour "Récepteur de l'histamine"
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Niperotidine
CAS :<p>Niperotidine is an antagonist of histamine H2-receptor.</p>Formule :C20H26N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.51Iodophenpropit dihydrobromide
CAS :<p>Iodophenpropit dihydrobromide: selective histamine H3 antagonist, reversible binding, high affinity (KD: 0.32 nM).</p>Formule :C15H20BrIN4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.22PF-03654746 Tosylate
CAS :<p>PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.</p>Formule :C25H32F2N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.6JNJ-39220675
CAS :<p>JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.</p>Formule :C21H24FN3O2Degré de pureté :98.13% - 99.89%Couleur et forme :SolidMasse moléculaire :369.43JNJ-28610244
CAS :<p>JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.</p>Formule :C16H21N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :271.36Hetramine
CAS :<p>Hetramine is a synthetic pyrimidine agent that possesses antihistamine and anti anaphylactic effects.</p>Formule :C15H20N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :256.35Fenethazine
CAS :<p>Fenethazine is an effective antihistamine used as an antiallergic drug.</p>Formule :C16H18N2SCouleur et forme :SolidMasse moléculaire :270.39HSR-609
CAS :<p>HSR-609, a histamine H1 receptor antagonist, is used potentially for the treatment of allergic rhinitis.</p>Formule :C21H21FN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.4Setastine
CAS :<p>Setastine, a highly selective H1 receptor antagonist, acts as a non-sedative antihistamine.</p>Formule :C22H28ClNOCouleur et forme :SolidMasse moléculaire :357.92BMH-7
CAS :<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Formule :C20H21N5ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :347.41Tei 6472
CAS :<p>Tei 6472 is a more hydrophilic form of TEI-1338 which is a novel, selective lipoxygenase inhibitor.</p>Formule :C32H39N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :545.67Nα-Methylhistamine dihydrochloride
CAS :<p>Nα-Methylhistamine dihydrochloride is a histamine H3 receptor agonist.</p>Formule :C6H13Cl2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :198.094Embramine
CAS :<p>Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.</p>Formule :C18H22BrNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.28PF 03654746 FA
<p>PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.</p>Formule :C19H26F2N2O3Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :368.42VUF 8430 dihydrobromide
CAS :<p>histamine H4 receptor full agonist</p>Formule :C4H12BrN5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.14Bavisant dihydrochloride
CAS :<p>Bavisant (JNJ-310010740) is an oral, selective H3 receptor antagonist enhancing wakefulness and cognition.</p>Formule :C19H29Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.36ICI 162,846
CAS :<p>ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.</p>Formule :C11H17F3N6ODegré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :306.29Setastine HCl
CAS :<p>Setastine HCl is a potent antagonist of histamine H1-receptor mediated responses.</p>Formule :C22H29Cl2NOCouleur et forme :SolidMasse moléculaire :394.38A 987306
CAS :<p>A-987306: Potent, oral histamine H4 antagonist; Ki: 3.4 nM (rat), 5.8 nM (human); reduces inflammation in mouse peritonitis.</p>Formule :C18H25N5OCouleur et forme :SolidMasse moléculaire :327.42Azelastine
CAS :<p>Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.</p>Formule :C22H24ClN3ODegré de pureté :99.35%Couleur et forme :White Crystal PowderMasse moléculaire :381.90Zaltidine
CAS :<p>Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.</p>Formule :C8H10N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :222.27JNJ-10191584
CAS :<p>JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammation</p>Formule :C13H15ClN4OCouleur et forme :SolidMasse moléculaire :278.74Alimemazine
CAS :<p>Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.</p>Formule :C18H22N2SDegré de pureté :98%Couleur et forme :Crystals SolidMasse moléculaire :298.45Aminopotentidine
CAS :<p>H2 antagonist</p>Formule :C26H35N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.6Zolantidine dimaleate
CAS :<p>H2 receptor antagonist</p>Formule :C26H31N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.61BMY-25271
CAS :<p>BMY-25271 is an antagonist of histamine H2 receptor.</p>Formule :C12H19N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.44ABT-239
CAS :<p>ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.</p>Formule :C22H22N2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :330.42(R)-Mequitazine
CAS :<p>(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.</p>Formule :C20H22N2SCouleur et forme :SolidMasse moléculaire :322.47A-304121
CAS :<p>A-304121 is a histamine H(3) receptor.</p>Formule :C20H29N3O3Couleur et forme :SolidMasse moléculaire :359.46OUP-186
CAS :<p>OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.</p>Formule :C19H30ClN3SCouleur et forme :SolidMasse moléculaire :367.98JNJ 10181457 dihydrochloride
CAS :<p>JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.</p>Formule :C20H28N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.45Mianserin
CAS :<p>Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.</p>Formule :C18H20N2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :264.36Wy 49051
CAS :<p>Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).</p>Formule :C28H33N5O3Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :487.59ROS 234
CAS :<p>ROS 234 is a potent H3 antagonist with pKB 9.46 for Guinea-pig ileum and pKi 8.90 for Rat cortex; ED50 of 19.12 mg/kg in rats, but with limited central access.</p>Formule :C13H15N5Couleur et forme :SolidMasse moléculaire :241.29PF-03654746
CAS :<p>PF-03654746: selective H3 antagonist, boosts cognition in Alzheimer's, may treat allergic rhinitis.</p>Formule :C18H24F2N2ODegré de pureté :98.85% - 99.57%Couleur et forme :SolidMasse moléculaire :322.39AZD5213
CAS :<p>AZD5213: selective human H3 receptor antagonist, pKi 9.3, for sleep/cognition research.</p>Formule :C19H25N3O2Couleur et forme :SolidMasse moléculaire :327.42Repirinast
CAS :<p>Repirinast is a mediator release inhibitor. It is used to treat asthma.</p>Formule :C20H21NO5Couleur et forme :SolidMasse moléculaire :355.38Immepip
CAS :<p>Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.</p>Formule :C9H15N3Couleur et forme :SolidMasse moléculaire :165.24Phenyltoloxamine
CAS :<p>Phenyltoloxamine (Bistrimin): antihistamine with sedative, analgesic properties, and Sigma-1 receptor affinity (Ki=160 nM).</p>Formule :C17H21NOCouleur et forme :SolidMasse moléculaire :255.35Mizolastine dihydrochloride
CAS :<p>Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM).</p>Formule :C24H27Cl2FN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.42GSK 189254 HCl
CAS :<p>GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.</p>Formule :C21H26ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.9GSK334429
CAS :<p>GSK334429 is an antagonist of histamine H3 receptor.</p>Formule :C20H29F3N4OCouleur et forme :SolidMasse moléculaire :398.47Sequifenadine
CAS :<p>Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].</p>Formule :C22H27NOCouleur et forme :SolidMasse moléculaire :321.46A-940894
CAS :<p>A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.</p>Formule :C17H21N5Couleur et forme :SolidMasse moléculaire :295.38Loratadine N-oxide
CAS :<p>Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.</p>Formule :C22H23ClN2O3Couleur et forme :SolidMasse moléculaire :398.88MK-0249
CAS :<p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>Formule :C23H24F3N3O2Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :431.45N-Acetylhistamine
CAS :<p>N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.</p>Formule :C7H11N3ODegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :153.18Izuforant
CAS :<p>Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).</p>Formule :C12H12BrN7Couleur et forme :SolidMasse moléculaire :334.17A-943931
CAS :<p>A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.</p>Formule :C17H21N5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :295.38Pitolisant oxalate
CAS :<p>Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Formule :C19H28ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.88Pirolate
CAS :<p>Pirolate is a receptor of histamine H1.</p>Formule :C16H15N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.31Bepotastine tosylate
CAS :<p>Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.</p>Formule :C28H33ClN2O6SCouleur et forme :SolidMasse moléculaire :561.09VUF-10497
CAS :<p>VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).</p>Formule :C18H20ClN5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.9A331440
CAS :<p>A331440 is an modulator of L-histidine and histamine H3 receptor.</p>Formule :C22H27N3OCouleur et forme :SolidMasse moléculaire :349.47Phenindamine
CAS :<p>Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].</p>Formule :C19H19NCouleur et forme :SolidMasse moléculaire :261.36Acreozast
CAS :<p>Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.</p>Formule :C15H14ClN3O6Couleur et forme :SolidMasse moléculaire :367.74CP19
CAS :<p>CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].</p>Formule :C26H30N2O5Couleur et forme :SolidMasse moléculaire :450.53Phenindamine Tartrate
CAS :<p>Phenindamine Tartrate, an antihistamine and anticholinergic, treats colds and allergies like sneezing and rashes.</p>Formule :C23H25NO6Couleur et forme :SolidMasse moléculaire :411.454INCB38579
CAS :<p>INCB38579: Oral, selective H4 antagonist; crosses brain barrier; IC50s - hH4R: 4.8 nM, mH4R: 42 nM, rH4R: 32 nM; anti-inflammatory and antipruritic.</p>Formule :C25H34N6OCouleur et forme :SolidMasse moléculaire :434.58Thioperamide
CAS :<p>histamine H3 and H4 antagonist/inverse agonist</p>Formule :C15H24N4SDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :292.44VUF 5681 dihydrobromide
CAS :<p>histamine H3 receptor silent antagonist</p>Formule :C11H21Br2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.11Carbinoxamine
CAS :<p>Carbinoxamine: antihistamine for hay fever, angioedema, rhinitis, mild urticaria, dermatographism, allergic conjunctivitis; an H1-antagonist.</p>Formule :C16H19ClN2ODegré de pureté :98%Couleur et forme :LiquidMasse moléculaire :290.79Nebidrazine
CAS :<p>Nebidrazine is an alpha-adrenoceptor agonist.</p>Formule :C9H8Cl2N6Couleur et forme :SolidMasse moléculaire :271.11Toreforant
CAS :<p>Toreforant is an effective and selective histamine H4 receptor antagonist (Ki at the human receptor: 8.4 nM).</p>Formule :C23H32N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.54VUF 8430
CAS :<p>VUF 8430 is a selective agonist for the H4 receptor.</p>Formule :C4H11N5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :161.23UK-9040
CAS :<p>UK-9040 inhibits gastric secretory.</p>Formule :C23H31NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.56SUN 1334H
CAS :<p>SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).</p>Formule :C23H28Cl2F2N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.38Adriforant hydrochloride
CAS :<p>Adriforant hydrochloride is an antagonist of histamine H4 receptor.</p>Formule :C13H25Cl3N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.74Seliforant
CAS :<p>Seliforant is a histamine H4 receptor antagonist.</p>Formule :C12H21N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :235.33(R)-(-)-α-Methylhistamine dihydrobromide
CAS :<p>(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective agonist of H3 histamine receptor( Kd of 50.3 nM).</p>Formule :C6H13Br2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287Amthamine dihydrobromide
CAS :<p>H2 agonist</p>Formule :C6H13Br2N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.06Carcainium chloride
CAS :<p>Carcainium chloride (Carcainium (chloride)) is a derivative of Lidocaine and possesses an antitussive effect.</p>Formule :C18H22ClN3O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :347.84DA 4643
CAS :<p>DA 4643, a histamine H2-receptor antagonist, binds similarly to mifentidine at the receptor.</p>Formule :C12H16Cl2N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.26Mequitamium iodide
CAS :<p>Mequitamium iodide is a PAF inhibitor, curbing platelet aggregation and bronchoconstriction without blocking PAF receptors.</p>Formule :C21H25IN2SCouleur et forme :SolidMasse moléculaire :464.41Impentamine dihydrobromide
CAS :<p>Impentamine dihydrobromide is a histamine H3 receptor antagonist.</p>Formule :C8H17Br2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.05Chloracyzine
CAS :<p>Chloracyzine lowers heart oxygen use, shrinks coronary flow after brief dilation, slightly ups heart rate and arterial pressure.</p>Formule :C19H21ClN2OSCouleur et forme :SolidMasse moléculaire :360.9AHR-13268D
CAS :<p>AHR-13268D is a new agent of antiallergic/antihistaminic.</p>Formule :C28H29F2NNaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.53AHR-14310C
CAS :<p>AHR-14310C is a long-acting and nonsedating H1-antihistamine.</p>Formule :C24H28F2N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.49NNC-38-1049
CAS :<p>NNC-38-1049 is a novel selective antagonist of histamine H3.</p>Formule :C19H25ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.87Aplysamine-1
CAS :<p>Aplysamine-1 is an antagonist of histamine H3 receptor.</p>Formule :C15H24Br2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.17Linadryl hydrochloride
CAS :<p>Linadryl hydrochloride may have antihistamine activity.</p>Formule :C19H24ClNO2Couleur et forme :SolidMasse moléculaire :333.85Ramixotidine
CAS :<p>Ramixotidine is a competitive antagonist of histamine H2-receptor.</p>Formule :C16H21N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.42JNJ 10191584 maleate
CAS :<p>JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM).</p>Formule :C17H19ClN4O5Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :394.81Dacemazine hydrochloride
CAS :<p>Dacemazine is a phenothiazine derivative that acts as a histamine antagonist at the H1 subtype. It was also assessed as a possible anticancer drug.</p>Formule :C16H17ClN2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.84Carcinine
CAS :<p>Carcinine ditrifluoroacetate is a H3 receptor antagonist.</p>Formule :C8H14N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :182.22Azatadine
CAS :<p>Azatadine is histamine and cholinergic inhibitor (IC50: 6.5 nM and 10 nM, respectively).</p>Formule :C20H22N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :290.4H3R-IN-1 Hydrochloride
CAS :<p>H3R-IN-1 Hydrochloride is an inverse agonist of histamine receptor 3( H3R ) .</p>Formule :C19H24ClN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.86Impromidine
CAS :<p>Impromidine is a highly potent and specific agonist of the histamine H2 receptor.</p>Formule :C14H23N7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.44Rocastine
CAS :<p>Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.</p>Formule :C13H19N3OSDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :265.37H3 receptor-MO-1
CAS :<p>H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.</p>Formule :C20H27N3O2Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :341.45Vapitadine dihydrochloride
CAS :<p>Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.</p>Formule :C17H22Cl2N4ODegré de pureté :98.28% - 99.30%Couleur et forme :SolidMasse moléculaire :369.29Bamirastine
CAS :<p>Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect on</p>Formule :C31H37N5O3Degré de pureté :96.68%Couleur et forme :SolidMasse moléculaire :527.66CP-66948
CAS :<p>CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.</p>Formule :C13H20N6SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :292.4PF-03654764
CAS :<p>PF-03654764, an oral H3 receptor blocker, Ki: human 1.2 nM, rat 7.9 nM, used with Fexofenadine for allergic rhinitis.</p>Formule :C20H28F2N2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :350.45Lavoltidine
CAS :<p>Lavoltidine (Loxtidine) is potent and selective H2 receptor antagonist, oral and irreversible,inhibits gastric acid secretion, gastroesophageal reflux disease.</p>Formule :C19H29N5O2Degré de pureté :98.30% - 98.36%Couleur et forme :SolidMasse moléculaire :359.47UR-PI376
CAS :<p>UR-PI376 is a selective histamine H4 receptor agonist with low H1/H2 activity and moderate H3 affinity.</p>Formule :C17H22N6SCouleur et forme :SolidMasse moléculaire :342.46GSK-239512
CAS :<p>GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.</p>Formule :C23H27N3O2Degré de pureté :99.62% - 99.74%Couleur et forme :SolidMasse moléculaire :377.48S-1-Propenyl-L-cysteine
CAS :<p>S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensive</p>Formule :C6H11NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :161.22ROS 234 dioxalate
CAS :<p>ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)</p>Formule :C17H19N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.37Nedocromil
CAS :<p>Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).</p>Formule :C19H17NO7Degré de pureté :95% - 97.34%Couleur et forme :SolidMasse moléculaire :371.34FR-A 19
CAS :<p>FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.</p>Formule :C25H34Cl3F2N5Couleur et forme :SolidMasse moléculaire :548.93VUF 8328
CAS :<p>VUF 8328 is an agonist of histamine H(3) receptor.</p>Formule :C7H12N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :184.26Adriforant
CAS :<p>Adriforant (PF-3893787,ZPL-3893797) is a competitive histamine receptor 4 h4 antagonist that antagonizes histamine-induced phosphorylation of ERK, inflammation.</p>Formule :C13H22N6Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :262.35FRG8701
CAS :<p>FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.</p>Formule :C22H30N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.55ReN-1869 hydrochloride
CAS :<p>ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.</p>Formule :C24H28ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.94H4R antagonist 1
CAS :<p>H4R antagonist 1: selective histamine H4R inhibitor, IC50 27 nM, no affinity for H1R, H2R, H3R.</p>Formule :C11H11BrN8Couleur et forme :SolidMasse moléculaire :335.16(±)-Tazifylline
CAS :<p>(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.</p>Formule :C23H32N6O3SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :472.6Noberastine
CAS :<p>Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.</p>Formule :C17H21N5ODegré de pureté :99.72% - >99.99%Couleur et forme :SolidMasse moléculaire :311.38KSK68
CAS :<p>KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.</p>Formule :C23H28N2O2Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :364.48Immethridine dihydrobromide
CAS :<p>Immethridine dihydrobromide is a histamine H3 receptor agonist.</p>Formule :C9H11Br2N3Degré de pureté :97.61% - 98.14%Couleur et forme :SolidMasse moléculaire :321.01D18024
CAS :<p>D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.</p>Formule :C29H31ClFN3ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :492.03Impromidine hydrochloride
CAS :<p>Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.</p>Formule :C14H26Cl3N7SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :430.83Enerisant hydrochloride
CAS :<p>Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins</p>Formule :C22H31ClN4O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :434.96Linetastine
CAS :<p>Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.</p>Formule :C35H40N2O6Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :584.7Pitolisant
CAS :<p>Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Formule :C17H26ClNODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :295.85KSK94
CAS :<p>KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.</p>Formule :C25H26N4ODegré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :398.5Irdabisant
CAS :<p>Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.</p>Formule :C18H23N3O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :313.39Efletirizine
CAS :<p>Efletirizine (UCB-28754), a histamine blocker and 5-LO inhibitor, aids in topical allergy treatment.</p>Formule :C21H24F2N2O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :390.42Antihistamine-1
CAS :<p>Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。</p>Formule :C23H24FN5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :389.47NP10679
CAS :<p>NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.</p>Formule :C23H26F3N3O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :449.47Proxyfan
CAS :<p>Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.</p>Formule :C13H16N2ODegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :216.28ReN-1869
CAS :<p>ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseases</p>Formule :C24H27NO2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :361.48DF-1111301
CAS :<p>DF-1111301 is a novel anti-allergic compound with anti-histamine H1 and anti-PAF activity.</p>Formule :C15H25Cl2N3ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :334.29Eclazolast
CAS :<p>Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.</p>Formule :C12H12ClNO4Degré de pureté :98.36% - 98.58%Couleur et forme :SolidMasse moléculaire :269.68KP136
CAS :<p>KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).</p>Formule :C16H18N4O3Degré de pureté :98.3% - 98.61%Couleur et forme :SolidMasse moléculaire :314.34Bavisant
CAS :<p>Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.</p>Formule :C19H27N3O2Degré de pureté :99.21% - 99.65%Couleur et forme :SolidMasse moléculaire :329.44Abt-288
CAS :<p>ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.</p>Formule :C23H24N4ODegré de pureté :98.17% - 98.49%Couleur et forme :SolidMasse moléculaire :372.46Clemastine
CAS :<p>Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.</p>Formule :C21H26ClNODegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :343.89JZP-361
CAS :<p>JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.</p>Formule :C22H20ClN5ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :405.88JNJ-28583867
CAS :<p>JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.</p>Formule :C24H32N2O2SCouleur et forme :SolidMasse moléculaire :412.59Cipralisant maleate
CAS :<p>Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.</p>Formule :C18H24N2O4Couleur et forme :SolidMasse moléculaire :332.39CI-949
CAS :<p>CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).</p>Formule :C20H20N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.41Ebrotidine
CAS :<p>Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.</p>Formule :C14H17BrN6O2S3Degré de pureté :97.519%Couleur et forme :SolidMasse moléculaire :477.42GSK-1004723
CAS :<p>GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.</p>Formule :C39H49ClN4O2Couleur et forme :SolidMasse moléculaire :641.28Quinotolast sodium
CAS :<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Formule :C17H12N6NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.312UCB-35440
CAS :<p>UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.</p>Formule :C31H34ClN5O4Couleur et forme :SolidMasse moléculaire :576.09Minocromil
CAS :<p>Minocromil is a new agent of Anti-asthmatic.</p>Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.33A-349821
CAS :<p>A-349821 is an H3 receptor agonist radioligand.</p>Formule :C28H35F3N2O5Couleur et forme :SolidMasse moléculaire :536.59GT-2331
CAS :<p>GT-2331 is a histamine H3 receptor antagonist.</p>Formule :C14H20N2Couleur et forme :SolidMasse moléculaire :216.32Levocabastine
CAS :<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formule :C26H29FN2O2Couleur et forme :SolidMasse moléculaire :420.52H3 receptor antagonist 1
CAS :<p>H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.</p>Formule :C20H28F2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45H4R antagonist 2
CAS :<p>H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoid</p>Formule :C13H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.31Cipralisant
CAS :<p>Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.</p>Formule :C14H20N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.32Levocabastine hydrochloride
CAS :<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Formule :C26H30ClFN2O2Couleur et forme :SolidMasse moléculaire :456.98ST-1006
CAS :<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Formule :C16H20Cl2N6Degré de pureté :98.87% - 99.96%Couleur et forme :SolidMasse moléculaire :367.28Enerisant
CAS :<p>Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.</p>Formule :C22H30N4O3Degré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :398.50Tixanox sodium
CAS :<p>Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.</p>Formule :C15H9NaO5SCouleur et forme :SolidMasse moléculaire :324.28CI-624
CAS :<p>CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.</p>Formule :C8H8N2SCouleur et forme :SolidMasse moléculaire :164.228H3R antagonist 5
CAS :<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Formule :C23H32N2O4Couleur et forme :SolidMasse moléculaire :400.511Arpromidine
CAS :<p>Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.</p>Formule :C21H25FN6Couleur et forme :SolidMasse moléculaire :380.462H1R ligand-1
CAS :<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Formule :C19H23NOCouleur et forme :SolidMasse moléculaire :281.392Nedocromil sodium
CAS :<p>Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.</p>Formule :C19H17NNaO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.335UR-AK49
CAS :<p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>Formule :C16H27N5OCouleur et forme :SolidMasse moléculaire :305.42FR-145715
CAS :<p>FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.</p>Formule :C16H21N5O2SCouleur et forme :SolidMasse moléculaire :347.44Histamine H3 antagonist-1
CAS :<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Formule :C24H28F3N3O2Couleur et forme :SolidMasse moléculaire :447.49H3R antagonist 1
CAS :<p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>Formule :C19H23N3O3Couleur et forme :SolidMasse moléculaire :341.4(R)-(-)-α-Methylhistamine dihydrochloride
CAS :<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Formule :C6H13Cl2N3Couleur et forme :SolidMasse moléculaire :198.09Imetit dihydrobromide
CAS :<p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>Formule :C6H12Br2N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.06
