Récepteur de l'histamine
Les récepteurs de l'histamine sont des GPCR qui médiatisent les effets de l'histamine, une amine biogène impliquée dans les réponses immunitaires, la sécrétion d'acide gastrique et la neurotransmission. Il existe quatre sous-types de récepteurs de l'histamine (H1, H2, H3 et H4), chacun jouant des rôles distincts dans les réactions allergiques, la fonction gastrique et l'activité du système nerveux central. Les antagonistes des récepteurs de l'histamine sont largement utilisés dans le traitement des allergies, des ulcères gastriques et du mal des transports. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de récepteurs de l'histamine de haute qualité pour soutenir vos recherches en immunologie, gastroentérologie et neuropharmacologie.
385 produits trouvés pour "Récepteur de l'histamine"
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Eclazolast
CAS :Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.Formule :C12H12ClNO4Degré de pureté :98.29% - 98.61%Couleur et forme :SolidMasse moléculaire :269.68Ref: TM-T25360
1mg112,00€5mg261,00€10mg396,00€25mg655,00€50mg888,00€100mg1.251,00€500mg2.493,00€1mL*10mM (DMSO)249,00€Irdabisant
CAS :Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Formule :C18H23N3O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :313.39UCB-35440
CAS :UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Formule :C31H34ClN5O4Couleur et forme :SolidMasse moléculaire :576.09Meclizine N-oxide
CAS :Meclizine N-oxide, a metabolite of the histamine H1 receptor antagonist meclizine (1), also acts as a degradation product and potential impurity in commercial meclizine preparations (2).Formule :C25H27ClN2OCouleur et forme :SolidMasse moléculaire :407Levocabastine hydrochloride
CAS :Levocabastine HCl is an agent with antihistaminic activity.Formule :C26H30ClFN2O2Couleur et forme :SolidMasse moléculaire :456.98Quinotolast sodium
CAS :Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.Formule :C17H12N6NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.312A-349821
CAS :A-349821 is an H3 receptor agonist radioligand.Formule :C28H35F3N2O5Couleur et forme :SolidMasse moléculaire :536.59CI-949
CAS :CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).Formule :C20H20N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.41Ebrotidine
CAS :Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.Formule :C14H17BrN6O2S3Degré de pureté :97.519%Couleur et forme :SolidMasse moléculaire :477.42Minocromil
CAS :Minocromil is a new agent of Anti-asthmatic.Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.33GT-2331
CAS :GT-2331 is a histamine H3 receptor antagonist.Formule :C14H20N2Couleur et forme :SolidMasse moléculaire :216.32APD-916
CAS :APD-916, an H3 receptor antagonist, exhibits favorable pharmacokinetic properties. Oral administration of APD-916 has been demonstrated to enhance wakefulness in various animal models.Formule :C23H31NO3SCouleur et forme :SolidMasse moléculaire :401.56Embramine hydrochloride
CAS :Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Formule :C18H23BrClNOCouleur et forme :SolidMasse moléculaire :384.74JNJ-28583867
CAS :JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Formule :C24H32N2O2SCouleur et forme :SolidMasse moléculaire :412.59GSK-1004723
CAS :GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Formule :C39H49ClN4O2Couleur et forme :SolidMasse moléculaire :641.28Cipralisant
CAS :Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Formule :C14H20N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.32Hydroxydione
CAS :Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].Formule :C21H32O3Couleur et forme :SolidMasse moléculaire :332.48Cipralisant maleate
CAS :Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Formule :C18H24N2O4Couleur et forme :SolidMasse moléculaire :332.39H3 receptor antagonist 1
CAS :H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Formule :C20H28F2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Levocabastine
CAS :Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.Formule :C26H29FN2O2Couleur et forme :SolidMasse moléculaire :420.52H4R antagonist 2
CAS :H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFormule :C13H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.31ST-1006
CAS :ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.Formule :C16H20Cl2N6Degré de pureté :99.96% - 99.98%Couleur et forme :SolidMasse moléculaire :367.28Ref: TM-T34709
1mg86,00€5mg188,00€10mg299,00€25mg487,00€50mg600,00€100mg743,00€200mg990,00€1mL*10mM (DMSO)187,00€Enerisant
CAS :Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.Formule :C22H30N4O3Degré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :398.50Ref: TM-T67828
1mg49,00€2mg67,00€5mg102,00€10mg166,00€25mg339,00€50mg439,00€100mg610,00€200mg827,00€1mL*10mM (DMSO)111,00€H3R antagonist 1
CAS :H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Formule :C19H23N3O3Couleur et forme :SolidMasse moléculaire :341.4Tixanox sodium
CAS :Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Formule :C15H9NaO5SCouleur et forme :SolidMasse moléculaire :324.28H3R antagonist 5
CAS :H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Formule :C23H32N2O4Couleur et forme :SolidMasse moléculaire :400.511CI-624
CAS :CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Formule :C8H8N2SCouleur et forme :SolidMasse moléculaire :164.228H1R ligand-1
CAS :H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.Formule :C19H23NOCouleur et forme :SolidMasse moléculaire :281.392Sitamaquine hydrochloride
CAS :Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Formule :C21H35Cl2N3OCouleur et forme :SolidMasse moléculaire :416.43Arpromidine
CAS :Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.Formule :C21H25FN6Couleur et forme :SolidMasse moléculaire :380.462Nedocromil sodium
CAS :Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Formule :C19H17NNaO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.335Histamine H3 antagonist-1
CAS :Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].
Formule :C24H28F3N3O2Couleur et forme :SolidMasse moléculaire :447.49ONO-8809
CAS :ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.Formule :C30H46BrNO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.66(R)-(-)-α-Methylhistamine dihydrochloride
CAS :R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formule :C6H13Cl2N3Couleur et forme :SolidMasse moléculaire :198.09Imetit dihydrobromide
CAS :Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formule :C6H12Br2N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.06
