Récepteur opioïde
Les récepteurs opioïdes sont un groupe de récepteurs couplés aux protéines G qui médiatisent les effets des opioïdes endogènes et exogènes. Ces récepteurs jouent un rôle central dans la modulation de la douleur, la régulation de l'humeur et les comportements addictifs. Les agonistes et antagonistes des récepteurs opioïdes sont largement utilisés dans la gestion de la douleur et le traitement des dépendances, ainsi que dans la recherche sur les troubles neurologiques et psychiatriques. Chez CymitQuimica, nous offrons une sélection complète de modulateurs des récepteurs opioïdes de haute qualité pour soutenir vos recherches en neurobiologie, gestion de la douleur et thérapie contre les addictions.
297 produits trouvés pour "Récepteur opioïde"
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Apitegromab
CAS :<p>Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including</p>Degré de pureté :95% - 97.59% (SDS-PAGE); 99.78% (SEC-HPLC)Couleur et forme :LiquidBTRX-335140
CAS :<p>BTRX-335140 (CYM-53093) is a potent and selective orally active κ-opioid receptor (KOR) antagonist with antagonistic activity.Cost-effective and quality-assured.</p>Formule :C25H32FN5O2Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :453.55Samidorphan HCl
CAS :<p>Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors.</p>Formule :C21H27ClN2O4Degré de pureté :96.79% - 97.85%Couleur et forme :SoildMasse moléculaire :406.9Alvimopan
CAS :<p>Alvimopan is a potent opioid antagonist targeting gut receptors to reverse opioid effects on motility.</p>Formule :C25H32N2O4Degré de pureté :99.47% - 99.78%Couleur et forme :SolidMasse moléculaire :424.53Sinomenine hydrochloride
CAS :<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Formule :C19H24ClNO4Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :365.851CP 866087
CAS :<p>CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.</p>Formule :C24H30N2O3SDegré de pureté :99.22% - 99.74%Couleur et forme :SolidMasse moléculaire :426.57ZT 52656A hydrochloride
CAS :<p>ZT 52656A is a selective agonist of kappa opioid, and used for the prevention or alleviation of pain in the eye.</p>Formule :C19H26ClF3N2ODegré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :390.87Naltrexone hydrochloride
CAS :<p>Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.</p>Formule :C20H24ClNO4Degré de pureté :98.72% - 99.65%Couleur et forme :White Crystalline PowderMasse moléculaire :377.862Matrine
CAS :<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formule :C15H24N2ODegré de pureté :97.16% - >99.99%Couleur et forme :SolidMasse moléculaire :248.36LY2940094
CAS :<p>LY2940094 (LY-2940094) decreases ethanol self-administration in animal models.</p>Formule :C22H23ClF2N4O2SDegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :480.96Moguisteine
CAS :<p>Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.</p>Formule :C16H21NO5SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :339.41Meptazinol hydrochloride
CAS :<p>Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.</p>Formule :C15H23NO·HClDegré de pureté :99.75%Couleur et forme :White SolidMasse moléculaire :269.81Loperamide hydrochloride
CAS :<p>Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.</p>Formule :C29H34Cl2N2O2Degré de pureté :99.91% - >99.99%Couleur et forme :Crystals Practically Insoluble In WaterMasse moléculaire :513.50Trimebutine maleate
CAS :<p>Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects.</p>Formule :C26H33NO9Degré de pureté :99.76% - 99.98%Couleur et forme :White SolidMasse moléculaire :503.55Ro 64-6198
CAS :<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Formule :C26H31N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.54DPDPE
CAS :<p>DPDPE is selective δ-opioid receptor agonist peptide.</p>Formule :C30H39N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :645.79Boc-ypgflt(O-tbu)
CAS :<p>Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.</p>Formule :C44H64N6O11Couleur et forme :SolidMasse moléculaire :853.01BAM-22P
CAS :<p>Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.</p>Formule :C130H184N38O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2839.22Dermorphin Analog
<p>Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.</p>Formule :C44H59N11O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :901.43TAN67
CAS :<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formule :C23H26Br2N2OCouleur et forme :SolidMasse moléculaire :506.282(Rac)-SNC80
CAS :<p>(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.</p>Formule :C28H39N3O2Couleur et forme :SolidMasse moléculaire :449.63β-Naltrexamine dihydrochloride
CAS :<p>β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.</p>Formule :C20H28Cl2N2O3Degré de pureté :95.98%Couleur et forme :SoildMasse moléculaire :415.35Axelopran
CAS :<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formule :C26H39N3O4Couleur et forme :SolidMasse moléculaire :457.61Nociceptin(1-7)
CAS :<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Formule :C31H41N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :655.709Orphanin FQ(1-11)
CAS :<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formule :C49H75N15O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1098.2CTOP
CAS :<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Formule :C50H67N11O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.28β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Formule :C156H249F3N42O46SCouleur et forme :SolidMasse moléculaire :3537.96Frakefamide TFA
<p>Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.</p>Formule :C32H35F4N5O7Couleur et forme :SolidMasse moléculaire :677.64Ac-RYYRWK-NH2
CAS :<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formule :C49H69N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1012.17[(pF)Phe4]Nociceptin(1-13)NH2
CAS :<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Formule :C61H99FN22O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1399.6Akuammicine
CAS :<p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>Formule :C20H22N2O2Couleur et forme :SolidMasse moléculaire :322.408Gluten Exorphin B5
CAS :<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Formule :C30H38N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.66Cebranopadol hemicitrate
CAS :<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Couleur et forme :SolidNaldemedine
CAS :<p>Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.</p>Formule :C32H34N4O6Couleur et forme :SolidMasse moléculaire :570.64KOR agonist 5
<p>KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).</p>Formule :C38H38N2O5Couleur et forme :SolidMasse moléculaire :602.72Dermorphin
CAS :<p>Dermorphin is agonist of μ-opioid receptor (MOR) agonist.</p>Formule :C40H50N8O10Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :802.87ICI 174,864
CAS :<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formule :C38H53N5O7Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :691.87Dynorphin B (1-13)
CAS :Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formule :C74H115N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1570.84Neuropeptide AF (human)
CAS :<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Formule :C90H132N26O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1978.17Biphalin TFA
CAS :<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Formule :C46H56N10O10·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :909.00 (free base)Ac-RYYRIK-NH2
CAS :<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Formule :C44H70N14O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :939.12[DPro10] Dynorphin A (1-11)acetate,porcine
<p>[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.</p>Formule :C65H107N21O15Degré de pureté :99.05%Couleur et forme :SoildMasse moléculaire :1422.7PL-017
CAS :<p>μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.</p>Formule :C29H37N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.64U-54494A hydrochloride
CAS :<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Formule :C18H25Cl3N2OCouleur et forme :SolidMasse moléculaire :391.76Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Couleur et forme :Odour SolidKOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formule :C21H25N3Couleur et forme :SolidMasse moléculaire :319.44SNC 80
CAS :<p>SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.</p>Formule :C28H39N3O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :449.63DAMGO (TFA)
CAS :<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Formule :C28H36F3N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :627.61[Nphe1]Nociceptin(1-13)NH2
CAS :<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Formule :C61H100N22O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1381.6HINT1-IN-1
<p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>Formule :C23H24N8O5Couleur et forme :SolidMasse moléculaire :492.49
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