SGLT
Les co-transporteurs sodium-glucose (SGLT) sont des protéines membranaires qui facilitent la réabsorption du glucose dans les reins en couplant le transport du glucose avec des ions sodium. Les inhibiteurs des SGLT constituent une classe importante de médicaments utilisés dans le traitement du diabète de type 2, car ils aident à réduire les niveaux de glucose dans le sang en empêchant la réabsorption du glucose dans les tubules rénaux. Ces inhibiteurs sont également étudiés pour leurs bénéfices potentiels dans la protection cardiovasculaire et rénale. Chez CymitQuimica, nous offrons une gamme de modulateurs SGLT de haute qualité pour soutenir vos recherches en diabète, physiologie rénale et troubles métaboliques.
31 produits trouvés pour "SGLT"
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KGA-2727
CAS :KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Formule :C26H40N4O8Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :536.62Ref: TM-T15656
1mg109,00€2mg158,00€5mg260,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)305,00€Sergliflozin A
CAS :Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Formule :C20H24O7Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :376.4O-Desethyl Dapagliflozin
CAS :O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Formule :C19H21ClO6Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :380.82Ref: TM-T67849
1mg54,00€5mg114,00€10mg177,00€25mg304,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)128,00€Canagliflozin (Standard)
CAS :Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).Formule :C24H25FO5SCouleur et forme :SolidMasse moléculaire :444.52Sotagliflozin
CAS :Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFormule :C21H25ClO5SDegré de pureté :99% - 99.86%Couleur et forme :SolidMasse moléculaire :424.94Ref: TM-T3547
1mg46,00€2mg57,00€5mg87,00€10mg131,00€25mg248,00€50mg378,00€100mg560,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Empagliflozin
CAS :Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Formule :C23H27ClO7Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :450.91Ref: TM-T1766
1g278,00€5mg47,00€10mg60,00€50mg79,00€100mg96,00€200mg144,00€500mg188,00€1mL*10mM (DMSO)50,00€Mizagliflozin
CAS :Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Formule :C28H44N4O8Degré de pureté :98.66% - 99.67%Couleur et forme :SolidMasse moléculaire :564.67Ref: TM-T16083
1mg66,00€2mg96,00€5mg144,00€10mg227,00€25mg455,00€50mg645,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)173,00€Dapagliflozin
CAS :Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formule :C21H25ClO6Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :408.87Ref: TM-T2389
5mg47,00€10mg60,00€25mg77,00€50mg94,00€100mg107,00€200mg142,00€1500mg284,00€1mL*10mM (DMSO)52,00€Enavogliflozin
CAS :Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Formule :C24H27ClO6Degré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :446.92Ref: TM-T38843
1mg147,00€5mg358,00€10mg560,00€25mg973,00€50mg1.333,00€100mg1.765,00€1mL*10mM (DMSO)394,00€Ipragliflozin
CAS :Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Formule :C21H21FO5SDegré de pureté :99.38% - 99.70%Couleur et forme :SolidMasse moléculaire :404.45T-1095
CAS :T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formule :C26H28O11Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :516.49Ref: TM-T9590
1mg50,00€2mg71,00€5mg90,00€10mg130,00€25mg207,00€50mg370,00€100mg530,00€1mL*10mM (DMSO)127,00€Phloretin
CAS :Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.
Formule :C15H14O5Degré de pureté :98.53% - >99.99%Couleur et forme :SolidMasse moléculaire :274.27Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS :Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Formule :C24H35ClO9Degré de pureté :99.88% - 99.94%Couleur et forme :SolidMasse moléculaire :502.98Canagliflozin
CAS :Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Formule :C24H25FO5SDegré de pureté :98.01% - >99.99%Couleur et forme :SolidMasse moléculaire :444.52Ref: TM-T1782
2mg35,00€5mg50,00€10mg66,00€25mg87,00€50mg96,00€100mg123,00€500mg274,00€1mL*10mM (DMSO)52,00€Phlorizin
CAS :Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
Formule :C21H24O10Degré de pureté :99.73% - 99.77%Couleur et forme :Solid CrystallineMasse moléculaire :436.41Tofogliflozin (hydrate)
CAS :Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Formule :C22H28O7Degré de pureté :97.03% - 98.78%Couleur et forme :SolidMasse moléculaire :404.45Ref: TM-T5016
1mg35,00€2mg49,00€5mg74,00€10mg109,00€25mg202,00€50mg324,00€100mg505,00€200mg717,00€1mL*10mM (DMSO)82,00€Ertugliflozin
CAS :PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Formule :C22H25ClO7Degré de pureté :99.89% - 99.96%Couleur et forme :SolidMasse moléculaire :436.88Bexagliflozin
CAS :Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Formule :C24H29ClO7Degré de pureté :98.99% - 99.89%Couleur et forme :SolidMasse moléculaire :464.94Ref: TM-T7217
1mg67,00€2mg95,00€5mg129,00€10mg187,00€25mg371,00€50mg552,00€100mg785,00€1mL*10mM (DMSO)137,00€Trilobatin
CAS :Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormule :C21H24O10Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)109,00€Canagliflozin hemihydrate
CAS :Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Formule :C48H52F2O11S2Degré de pureté :99.42% - 99.96%Couleur et forme :SolidMasse moléculaire :907.05
