Récepteur du glucagon
Les récepteurs du glucagon sont des GPCR qui médiatisent les effets du glucagon, une hormone impliquée dans la régulation de l'homéostasie du glucose en favorisant la dégradation du glycogène et la libération de glucose par le foie. Ces récepteurs sont essentiels dans la gestion des niveaux de sucre dans le sang et sont particulièrement intéressants dans l'étude du diabète et des troubles métaboliques. Les antagonistes des récepteurs du glucagon sont explorés comme traitements potentiels de l'hyperglycémie dans le diabète de type 2. Chez CymitQuimica, nous offrons une variété de modulateurs de récepteurs du glucagon de haute qualité pour soutenir vos recherches en endocrinologie, diabète et régulation métabolique.
194 produits trouvés pour "Récepteur du glucagon"
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NNC-0640
CAS :NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.Formule :C29H31N7O4SDegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :573.67Ref: TM-T7364
1mg46,00€2mg62,00€5mg90,00€10mg160,00€25mg281,00€50mg430,00€100mg620,00€1mL*10mM (DMSO)90,00€GLP-1 Receptor modulator 1
CAS :GLP-1 Receptormodulator 1 (Compound 7) is an effective positive allosteric modulator of the GLP-1 receptor. It is utilized in the research of obesity and type 2 diabetes.Formule :C18H21NOSMasse moléculaire :299.43GCGR antagonist 2
CAS :Orally active GCGR antagonist 2, a furan-2-carbohydrazide, binds hGluR at 2.3 nM. Blocks glucagon, inhibits rat receptor at 0.43 nM.Formule :C28H26N4O2Couleur et forme :SolidMasse moléculaire :450.53Glucagon receptor antagonists-2
CAS :Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Formule :C22H30FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.48GLP-1R agonist 1
CAS :GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.Formule :C32H29ClFN3O5Couleur et forme :SolidMasse moléculaire :590.04(S)-V-0219
(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.Formule :C20H25F3N4O2Couleur et forme :SolidMasse moléculaire :410.43Glucagon receptor antagonists-5
CAS :Oral indazole-based glucagon antagonist, Ki: 32 nM, may treat type 2 diabetes.Formule :C30H29ClF3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.02PF-06412154 HCl
CAS :PF-06412154 HCl is a glucagon receptor antagonist.Formule :C24H28ClN3O3Couleur et forme :SolidMasse moléculaire :441.96Efpeglenatide
CAS :Efpeglenatide is a long-acting GLP-1 receptor agonist that improves insulin sensitivity, lowers blood glucose, delays weight gain, and supports metabolic disease research.Degré de pureté :100% - 100%Couleur et forme :Solid(R)-V-0219
(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.Formule :C20H25F3N4O2Couleur et forme :SolidMasse moléculaire :410.43BAY-27-9955
CAS :BAY-27-9955 is a glucagon receptor antagonist.Formule :C23H31FOCouleur et forme :SolidMasse moléculaire :342.49MS012
CAS :MS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase (Kd = 46 ± 15 nM).Formule :C22H35N5O2Couleur et forme :SolidMasse moléculaire :401.55L-168049
CAS :L-168049: Human glucagon receptor antagonist, IC50 - 3.7 nM human, 63 nM murine, 60 nM canine.Formule :C24H20BrClN2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :467.79NNC 92-1687
CAS :NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.Formule :C15H12N2O3SDegré de pureté :98.70% - 99.96%Couleur et forme :SolidMasse moléculaire :300.33GLP-1 receptor agonist 3
CAS :GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.Formule :C31H30FN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.6LGD-6972 sodium
CAS :LGD-6972 sodium is a glucagon receptor antagonist.Formule :C43H46N2NaO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :725.9Antitumor agent-101
CAS :Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormule :C26H38N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.62MK3577
CAS :MK3577 is a glucagon receptor antagonist.Formule :C30H30ClFN2O3Couleur et forme :SolidMasse moléculaire :521.02GLP-1R agonist 10
CAS :GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).Formule :C29H29ClFN5O4Couleur et forme :SolidMasse moléculaire :566.02GLP-1R agonist 9
CAS :GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.Formule :C32H30ClF2N3O5Couleur et forme :SolidMasse moléculaire :610.05GLP-1R agonist 3
CAS :GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.Formule :C31H28FN5O4Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :553.58Glucagon receptor antagonists-3
CAS :Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.Formule :C22H30FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.48GLP-1R agonist 17
CAS :GLP-1R agonist 17 excels in stimulating GLP-1 receptors, useful for cardiovascular metabolic disease research.Formule :C28H26ClFN4O4SCouleur et forme :SolidMasse moléculaire :569.05MK 0893
CAS :MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.Formule :C32H27Cl2N3O4Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :588.48GLP-1R agonist 12
CAS :GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Formule :C34H36N6O4Couleur et forme :SolidMasse moléculaire :592.69Lotiglipron
CAS :Lotiglipron (PF-07081532) is a GLP-1R agonist that lowers blood glucose and may be used in the study of type 2 diabetes mellitus (T2DM) and excess obesity.Formule :C31H31ClN4O5Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :575.05LGD-6972
CAS :LGD-6972 is an antagonist of glucagon receptor.Formule :C43H46N2O5SDegré de pureté :98.8% - 99.62%Couleur et forme :SolidMasse moléculaire :702.9Ref: TM-T11845
1mg84,00€5mg177,00€10mg260,00€25mg447,00€50mg655,00€100mg888,00€1mL*10mM (DMSO)268,00€Adomeglivant
CAS :Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.Formule :C32H36F3NO4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :555.63GLP-1R agonist 32
CAS :GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.Formule :C32H31ClFN3O5Couleur et forme :SolidMasse moléculaire :592.06GLP-1R agonist 33
CAS :GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).Formule :C30H27FN6O4Couleur et forme :SolidMasse moléculaire :554.57GLP-1R modulator-1
CAS :GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Formule :C41H38ClFN6O4Couleur et forme :SolidMasse moléculaire :733.23GLP-1 receptor agonist 15
CAS :GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.Formule :C32H31ClFN3O5Couleur et forme :SolidMasse moléculaire :592.057LXT34
CAS :LXT34 (Example 2) is a GPR120 agonist with anti-inflammatory properties. This compound enhances GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells. LXT34 is applicable in studies related to inflammatory conditions, such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease.Formule :C18H21NO3SCouleur et forme :SolidMasse moléculaire :331.43GLP-1 receptor agonist 11
CAS :GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].Formule :C31H31ClFN3O4Couleur et forme :SolidMasse moléculaire :564.05PF-06372222
CAS :PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.Formule :C26H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.53DS79932728
CAS :DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Formule :C19H25N3OCouleur et forme :SolidMasse moléculaire :311.421GLP-1R agonist 8
CAS :GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formule :C33H32N4O5Couleur et forme :SolidMasse moléculaire :564.63GLP-1 receptor agonist 10
CAS :GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formule :C30H28F4N6O5Couleur et forme :SolidMasse moléculaire :628.57GLP-1 receptor agonist 12
CAS :Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Formule :C31H31FN6O4Masse moléculaire :570.61DA-302168S
CAS :DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.Formule :C33H24ClF2N3O5Couleur et forme :SolidMasse moléculaire :616.011GLP-1 receptor agonist 16
CAS :GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Formule :C33H31ClFN3O4Couleur et forme :SolidMasse moléculaire :588.068SCH-900822
CAS :SCH-900822 is a potent and selective glucagon receptor antagonist.Formule :C34H43Cl2N7O2Couleur et forme :SolidMasse moléculaire :652.66LSN3318839
CAS :LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and canFormule :C26H23Cl2N3O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :480.39Anti-GLP1R Antibody
Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.
Couleur et forme :Odour Liquid
