Récepteur de la dopamine
Les récepteurs de la dopamine sont un groupe de récepteurs couplés aux protéines G (GPCR) qui répondent au neurotransmetteur dopamine, jouant un rôle clé dans la régulation du mouvement, de la motivation, de la récompense et de plusieurs fonctions cognitives. Ces récepteurs sont divisés en familles de type D1 et de type D2, chacune ayant des fonctions et des profils pharmacologiques distincts. Les modulateurs des récepteurs de la dopamine sont largement étudiés pour leurs applications dans le traitement de la maladie de Parkinson, de la schizophrénie, de la dépendance et d'autres troubles neuropsychiatriques. Chez CymitQuimica, nous offrons une large gamme de modulateurs de récepteurs de la dopamine de haute qualité pour soutenir vos recherches en neurosciences, santé mentale et signalisation GPCR.
407 produits trouvés pour "Récepteur de la dopamine"
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Quinelorane dihydrochloride
CAS :<p>Dopamine D2 and D3 receptor agonist</p>Formule :C14H23ClN4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.81SKF-83822
CAS :<p>SKF-83822 is an agonist of dopamine D1-like receptor.</p>Formule :C20H22ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :343.85BRD5814
CAS :<p>BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.</p>Formule :C21H23ClF3NO2Couleur et forme :SolidMasse moléculaire :413.86SB-277011 dihydrochloride
CAS :<p>SB-277011 dihydrochloride: potent, selective D3 antagonist; orally bioavailable; crosses blood-brain barrier; pKi 8.0 for D3 receptor.</p>Formule :C28H32Cl2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.49PF2562
CAS :<p>PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP assay (EC50: 568 nM).</p>Formule :C19H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.37Odapipam
CAS :<p>Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).</p>Formule :C19H20ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.82Lenperone
CAS :<p>Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.</p>Formule :C22H23F2NO2Couleur et forme :SolidMasse moléculaire :371.42BAK2-66
CAS :<p>BAK2-66 is a selective antagonist of the dopamine D3 receptor.</p>Formule :C23H24Cl2FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.36Brl 20596
CAS :<p>Brl 20596 is a central dopamine antagonist in the class of anilide.</p>Formule :C20H24ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.88FAUC-3019
CAS :<p>FAUC-3019 is a partial agonist of the dopamine D(4) receptor.</p>Formule :C22H24N2OCouleur et forme :SolidMasse moléculaire :332.44Lergotrile
CAS :<p>Lergotrile is used as an enzyme Inhibitor (Prolactin).</p>Formule :C17H18ClN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.8CJB-090 2HCl
CAS :<p>CJB-090 2HCl is a partial agonist of the dopamine D3 receptor.</p>Formule :C26H30Cl4N4OCouleur et forme :SolidMasse moléculaire :556.35Gyki 32887
CAS :<p>Gyki 32887 is a dopamine agonist.</p>Formule :C23H28N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.57Amitifadine free base
CAS :<p>Amitifadine (DOV-21947/EB-1010), an antidepressant SNDRI, curbs binge drinking and negative effects in animals with alcoholism-depression.</p>Formule :C11H11Cl2NCouleur et forme :SolidMasse moléculaire :228.12A 69024
CAS :<p>A 69024 is a highly selective antagonist of dopamine D-1 receptor.</p>Formule :C20H24BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.31Seproxetine HCl
CAS :<p>Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier.</p>Formule :C16H17ClF3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.76Lergotrile mesylate
CAS :<p>Lergotrile mesylate, an ergoline derivative, suppresses prolactin in vivo and in vitro.</p>Formule :C18H22ClN3O3SCouleur et forme :SolidMasse moléculaire :395.9Bromperidol decanoate
CAS :<p>Bromperidol decanoate is an antipsychotic agent that is utilized for long-term maintenance treatment for schizophrenia.</p>Formule :C31H41BrFNO3Couleur et forme :SolidMasse moléculaire :574.56LY 171859
CAS :<p>LY 171859 is an agonist of D2-receptor.</p>Formule :C17H14O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.29Nor-SCH-12679 Maleate
CAS :<p>Nor-SCH-12679 Maleate is a D1-dopamine receptor antagonist.</p>Formule :C22H25NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.44Clothixamide
CAS :<p>Clothixamide（Clotixamide） is a thioxanthene derivative with antipsychotic activity.</p>Formule :C24H28ClN3OSDegré de pureté :95.51%Couleur et forme :SolidMasse moléculaire :442.02CI-943
CAS :<p>CI-943 is a novel potential antipsychotic drug that does not bind to dopamine (DA) receptors and has some developmental neurotoxicity.</p>Formule :C12H17N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.33'-Fluorobenzylspiperone maleate
CAS :<p>ligand for the D2 receptor</p>Formule :C34H35F2N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.66Butaclamol free base
CAS :<p>Butaclamol is a typical antipsychotic which was never marketed. It also acts as a dopamine receptor antagonist.</p>Formule :C25H31NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.52PD 118440
CAS :<p>PD 118440 is a Dopamine antagonist. PD 118440 is an orally active dopamine (DA) agonists with pronounced central nervous system effects.</p>Formule :C11H17N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :223.34Sch 24518
CAS :<p>Sc h24518 is an antagonist of D1 receptor.</p>Formule :C16H17BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.67Dicarbine
CAS :<p>Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite mid-brain stimulation.</p>Formule :C13H18N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :202.3L-750,667 Trihydrochloride
CAS :<p>L-750,667 Trihydrochloride is a selective D4 receptor antagonist, reverses the dopamine-induced inhibition of cAMP accumulation in the central nervous system.</p>Formule :C18H22Cl3IN4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :527.666-Chloromelatonin
CAS :<p>6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.</p>Formule :C13H15ClN2O2Degré de pureté :98.01% - 99.25%Couleur et forme :SolidMasse moléculaire :266.72A-77636
CAS :<p>A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50</p>Formule :C20H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.43D4R agonist-1
CAS :<p>D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.</p>Formule :C19H22N4SDegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :338.47PG 01037 dihydrochloride
CAS :<p>PG 01037 dihydrochloride (PG-01037 2HCl) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.</p>Formule :C26H28Cl4N4ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :554.34SKF83959
CAS :<p>SKF83959: dopamine D1 partial agonist, Ki: D1(1.18 nM), D5(7.56 nM), D2(920 nM), D3(399 nM); improves cognitive function in depression, Alzheimer's.</p>Formule :C18H20ClNO2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :317.81WAY-260022
CAS :<p>WAY-260022 is the norepinephrine transporter inhibitor.</p>Formule :C21H31F3N2O2Degré de pureté :97.61% - 99.41%Couleur et forme :SolidMasse moléculaire :400.48UNC9975
CAS :<p>UNC9975 is a D(2) receptor agonist with antipsychotic activity used in the study of neurologic disorders such as schizophrenia.</p>Formule :C23H28Cl2N4O2Degré de pureté :98.78% - 98.78%Couleur et forme :SolidMasse moléculaire :463.4Medifoxamine
CAS :<p>Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine</p>Formule :C16H19NO2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :257.33Halopemide
CAS :<p>Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).</p>Formule :C21H22ClFN4O2Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :416.88Benperidol
CAS :<p>Benperidol (Anquil), a butanone derivative, has antipsychotic effects and blocks D2 receptors; useful in PET scans.</p>Formule :C22H24FN3O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :381.44SB-277011
CAS :<p>SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).</p>Formule :C28H30N4ODegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :438.56Milenperone
CAS :<p>Milenperone (R 34009) is a novel anti-invasive compound for the control of behavioral disorders in patients with epilepsy and alcoholism.</p>Formule :C22H23ClFN3O2Degré de pureté :98.09% - 99.84%Couleur et forme :SolidMasse moléculaire :415.89PF-00217830
CAS :<p>PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.</p>Formule :C26H30N4O2Degré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :430.54U 99194 maleate
CAS :<p>U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.</p>Formule :C21H31NO6Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :393.47PD 168568 dihydrochloride
CAS :<p>PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).</p>Formule :C22H29Cl2N3ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :422.39NGD 94-1
CAS :<p>NGD 94-1 is a D4 receptor antagonist that can be used to study psychiatric disorders such as cognitive impairment.</p>Formule :C18H20N6Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :320.39MLS1547
CAS :<p>MLS1547 is a potent D2 receptor G protein-biased agonist (Ki=1.2 μM, EC50=0.37 μM in Ca2+ assay).</p>Formule :C19H19ClN4ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :354.837-Hydroxy-DPAT hydrobromide
CAS :<p>7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist that blocks dopamine reuptake, used in research on neurological diseases.</p>Formule :C16H26BrNODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :328.29GBR 12783 dihydrochloride
CAS :<p>GBR 12783 dihydrochloride inhibits dopamine uptake in rats/mice; IC50s: 1.8/1.2 nM. Enhances memory, boosts hippocampal acetylcholine.</p>Formule :C28H34Cl2N2ODegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :485.49Seridopidine
CAS :<p>Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.</p>Formule :C14H20FNO2SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :285.38Ordopidine
CAS :<p>Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.</p>Formule :C14H20FNO2SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :285.38Molindone
CAS :<p>Molindone: antipsychotic for schizophrenia; blocks dopamine, often paired with serotonin; dosage affects error/response rates.</p>Formule :C16H24N2O2Degré de pureté :99.37% - 99.46%Couleur et forme :Off-White SolidMasse moléculaire :276.37A-437203
CAS :<p>A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.</p>Formule :C20H27F3N6OSDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :456.53BP14979
CAS :<p>BP14979 is D3R-selective partial agonist.</p>Formule :C23H34N4O2Degré de pureté :98.29% - 99.73%Couleur et forme :SolidMasse moléculaire :398.54SK609 HCl
CAS :<p>SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.</p>Formule :C10H15Cl2NDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :220.14Remoxipride hydrochloride
CAS :<p>Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-</p>Formule :C16H24BrClN2O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :407.73CyPPA
CAS :<p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>Formule :C16H23N5Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :285.39Fananserin
CAS :<p>Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).</p>Formule :C23H24FN3O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :425.52CCG 203769
CAS :<p>CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.</p>Formule :C8H14N2O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :202.27Sonepiprazole
CAS :<p>Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation</p>Formule :C21H27N3O3SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :401.52CY 208-243
CAS :<p>CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.</p>Formule :C19H18N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :274.36Timiperone
CAS :<p>Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior.</p>Formule :C22H24FN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.51ABT-670
CAS :<p>ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.</p>Formule :C19H23N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.4SKF 81297
CAS :<p>SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].</p>Formule :C16H16ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :289.76FAUC-312
CAS :<p>FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.</p>Formule :C21H26N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.46LY3154885
CAS :<p>LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).</p>Formule :C23H23Cl2N3O2Couleur et forme :SolidMasse moléculaire :444.35Quinpirole dihydrochloride
CAS :<p>Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.</p>Formule :C13H23Cl2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.25Pentiapine
CAS :<p>Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.</p>Formule :C15H17N5SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :299.39AJ-76 hydrochloride
CAS :<p>AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.</p>Formule :C15H24ClNOCouleur et forme :SolidMasse moléculaire :269.81Carbidine dihydrochloride
CAS :<p>Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.</p>Formule :C13H20Cl2N2Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :275.217UWA-101 hydrochloride
CAS :<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Formule :C13H18ClNO2Couleur et forme :SolidMasse moléculaire :255.74SB-414796
CAS :<p>SB-414796 is a selective antagonist of the dopamine D3 receptor.</p>Formule :C29H36N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.69Naxagolide free base
CAS :<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Formule :C15H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.33Dihydrexidine
CAS :<p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>Formule :C17H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.32Z1078601926
CAS :<p>Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].</p>Formule :C14H19FN2OCouleur et forme :SolidMasse moléculaire :250.31Carmoxirole hydrochloride
CAS :<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Formule :C24H27ClN2O2Degré de pureté :99.37% - 99.62%Couleur et forme :SolidMasse moléculaire :410.94PW0464
CAS :<p>PW0464 ((Rac)-Razpipadon) is a non-catechol D1R agonist and potent omplete G protein biased ligand with an EC50 (Gs-cAMP)=5.8 nM for neurological disorders.</p>Formule :C19H17F2N3O4Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :389.35LBT 999
CAS :<p>LBT 999 is used as a dopamine reuptake inhibitor.</p>Formule :C20H26FNO2Couleur et forme :SolidMasse moléculaire :331.42JNJ-37822681 dihydrochloride
CAS :<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Formule :C17H19Cl2F5N4Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :445.26(+)-Dihydrexidine hydrochloride
CAS :<p>(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).</p>Formule :C17H18ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.78Brilaroxazine
CAS :<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formule :C22H25Cl2N3O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :450.36LY-368975
CAS :<p>LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.</p>Formule :C17H21NOSCouleur et forme :SolidMasse moléculaire :287.42SKF 81297 hydrobromide
CAS :<p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.</p>Formule :C16H17BrClNO2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :370.67CP-293019
CAS :<p>CP-293019 is a potent, selective antagonist of dopamine D4 receptor.</p>Formule :C19H22F2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.44-Amino-PPHT Hydrobromide
CAS :<p>4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.</p>Formule :C21H28N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.46PAOPA
CAS :<p>dopamine D2 receptor modulator</p>Formule :C11H18N4O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :254.29NMI 8739
CAS :<p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>Formule :C30H41NO3Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :463.65Lumateperone
CAS :<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formule :C24H28FN3ODegré de pureté :99.68% - 99.91%Couleur et forme :SolidMasse moléculaire :393.5Dopamine D3 receptor antagonist-1
<p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>Formule :C31H35Cl2N3O3Couleur et forme :SolidMasse moléculaire :568.53D4R antagonist-1
<p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>Formule :C21H25F2NO2Couleur et forme :SolidMasse moléculaire :361.43CM699
CAS :<p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>Formule :C24H29N3O2Couleur et forme :SolidMasse moléculaire :391.51Dopamine D3 receptor ligand-1
<p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>Formule :C27H29N5OCouleur et forme :SolidMasse moléculaire :439.55D1R antagonist 1
CAS :<p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>Formule :C22H26BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.35Dopamine D3 receptor antagonist-2
<p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>Formule :C23H27Cl2N3O3Couleur et forme :SolidMasse moléculaire :464.38UNC10099984A
CAS :<p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>Formule :C24H29Cl2N3O2Couleur et forme :SolidMasse moléculaire :462.41Neflumozide
CAS :<p>Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.</p>Formule :C22H23FN4O2Couleur et forme :SolidMasse moléculaire :394.44NMDAR antagonist 5
CAS :<p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>Formule :C17H21N3Couleur et forme :SolidMasse moléculaire :267.369D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Formule :C21H23ClF2N2O2Couleur et forme :SolidMasse moléculaire :408.87Lisuride
CAS :<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Formule :C20H26N4OCouleur et forme :SolidMasse moléculaire :338.45Cendifensine
CAS :<p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>Formule :C14H17Cl2NOCouleur et forme :SolidMasse moléculaire :286.197Disulergine
CAS :<p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>Formule :C17H24N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46Dinoxyline
CAS :<p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>Formule :C15H13NO3Couleur et forme :SolidMasse moléculaire :255.27
