Récepteur de la dopamine
Les récepteurs de la dopamine sont un groupe de récepteurs couplés aux protéines G (GPCR) qui répondent au neurotransmetteur dopamine, jouant un rôle clé dans la régulation du mouvement, de la motivation, de la récompense et de plusieurs fonctions cognitives. Ces récepteurs sont divisés en familles de type D1 et de type D2, chacune ayant des fonctions et des profils pharmacologiques distincts. Les modulateurs des récepteurs de la dopamine sont largement étudiés pour leurs applications dans le traitement de la maladie de Parkinson, de la schizophrénie, de la dépendance et d'autres troubles neuropsychiatriques. Chez CymitQuimica, nous offrons une large gamme de modulateurs de récepteurs de la dopamine de haute qualité pour soutenir vos recherches en neurosciences, santé mentale et signalisation GPCR.
444 produits trouvés pour "Récepteur de la dopamine".
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Bromopride
CAS :Bromopride (Valopride), a metoclopramide-like dopamine antagonist and prokinetic, is an antiemetic not sold in the US or UK.Formule :C14H22BrN3O2Degré de pureté :99.95%Couleur et forme :White SolidMasse moléculaire :344.25Ref: TM-T1175
2mg39,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg93,00€25mg167,00€50mg260,00€100mg409,00€200mg595,00€Tetrahydropalmatine
CAS :Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epilepticFormule :C21H25NO4Degré de pureté :99.59% - 99.95%Couleur et forme :SolidMasse moléculaire :355.43Ziprasidone hydrochloride
CAS :Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychoticFormule :C21H22CL2N4OSDegré de pureté :97.97% - 99.82%Couleur et forme :White SolidMasse moléculaire :449.4Talquetamab
CAS :Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Couleur et forme :Transparent LiquidMasse moléculaire :144.59 kDaQuetiapine hemifumarate
CAS :Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.Formule :C46H54N6O8S2Degré de pureté :99.32% - >99.99%Couleur et forme :White Crystalline SolidMasse moléculaire :883.09Paliperidone
CAS :Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic.Formule :C23H27FN4O3Degré de pureté :95% - 99.08%Couleur et forme :White SolidMasse moléculaire :426.48GR 103691
CAS :GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM).Formule :C30H35N3O3Degré de pureté :98.94% - 99.29%Couleur et forme :White SolidMasse moléculaire :485.62L-DOPA
CAS :L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa that is converted to dopamine by DOPA decarboxylase.Formule :C9H11NO4Degré de pureté :98.99% - 99.93%Couleur et forme :White SolidMasse moléculaire :197.19Oxidopamine hydrobromide
CAS :Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formule :C8H12BrNO3Degré de pureté :98.59% - 99.88%Couleur et forme :Brown SolidMasse moléculaire :250.09Haloperidol
CAS :Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function.Formule :C21H23ClFNO2Degré de pureté :98.69% - 98.97%Couleur et forme :SolidMasse moléculaire :375.86ONC206
CAS :ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations andFormule :C23H22F2N4ODegré de pureté :99.38% - 99.81%Couleur et forme :Yellow SolidMasse moléculaire :408.44[18F]-Labeled L-dopa precursor
CAS :[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].Formule :C35H36N2O7Couleur et forme :SolidMasse moléculaire :596.677-Hydroxy-PIPAT maleate
CAS :7-Hydroxy-PIPAT maleate is a D3R agonist.Formule :C16H22INOCouleur et forme :SolidMasse moléculaire :371.262Losulazine
CAS :Losulazine: a new antihypertensive, requires functional sympathetic nervous system; mechanism undefined.Formule :C27H22F4N4O3SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :558.55DETQ
CAS :DETQ enhances human D1 dopamine receptor signaling, EC50=5.8 nM, less effective in rats/mice, inactive on D5.Formule :C22H25Cl2NO3Couleur et forme :SolidMasse moléculaire :422.34Neuromedin N
CAS :Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.Formule :C38H63N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :745.95Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour SolidOctodrine
CAS :Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.Formule :C8H19NDegré de pureté :99.98%Couleur et forme :Clear Colorless To Light Yellow LiquidMasse moléculaire :129.24D3R ligand 1
D3R Ligand 1 (compound 23b) is a potent, selective antagonist of the dopamine D3 receptor (Ki=66 nM), incorporating a THPB template.Formule :C27H37NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.59ABT 724 trihydrochloride
CAS :ABT-724 trihydrochloride: selective D4 agonist; EC50=12.4nM(human),14.3nM(rat),23.2nM(ferret); for erectile dysfunction research.Formule :C17H22Cl3N5Degré de pureté :99.91%Couleur et forme :White SolidMasse moléculaire :402.75Ref: TM-T22019
5mg38,00€1mL*10mM (DMSO)42,00€10mg62,00€25mg119,00€50mg178,00€100mg268,00€200mg398,00€MLS1082
CAS :MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.Formule :C24H23N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :385.467-hydroxy Chlorpromazine (hydrochloride)
CAS :7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2 1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)Formule :C17H20Cl2N2OSMasse moléculaire :371.32Adrogolide HCl
CAS :Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.Formule :C22H26ClNO4SCouleur et forme :SolidMasse moléculaire :435.96(Iso)-WAY-260022
CAS :(Iso)-WAY-260022 ((Iso)-NRI-022) is a stereoisomer of WAY-260022, a norepinephrine reuptake inhibitor and selective inhibitor of 5-hydroxytryptamine and dopamine transport proteins.Formule :C21H31F3N2O2Degré de pureté :97.41% - 99.36%Couleur et forme :White OilMasse moléculaire :400.48Onzigolide
CAS :Onzigolide (BIM-23A760) is a dual agonist for D2R and SSTR2 with strong dopamine and somatostatin properties.Formule :C86H116N16O12S4Couleur et forme :SolidMasse moléculaire :1694.21Moperone
CAS :Moperone (R 1658) is an antagonist of both the D2 dopamine receptor (D2 dopamine receptor) and the D3 dopamine receptor (D3 dopamine receptor), with IC50 values for each of 1.0 nM.Formule :C22H26FNO2Couleur et forme :SolidMasse moléculaire :355.45D3R/MOR antagonist 1
Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nMFormule :C22H27Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38D3R/MOR antagonist 2
Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MORFormule :C25H31ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.98A 31472
CAS :A 31472 is a tetracyclic spiro amine that has affinity for dopamine D-2 receptors.Formule :C22H22ClNCouleur et forme :SolidMasse moléculaire :335.87Amisulpride hydrochloride
CAS :Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.Formule :C17H28ClN3O4SCouleur et forme :SolidMasse moléculaire :405.94Dopamine D2 receptor agonist-2
CAS :Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.Formule :C25H31Cl2N5OSDegré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :520.52Ref: TM-T60075
1mg35,00€5mg67,00€1mL*10mM (DMSO)86,00€10mg95,00€25mg140,00€50mg200,00€100mg298,00€200mg429,00€Clomipramine-D3
CAS :Clomipramine D3 is deuterium-labeled Clomipramine, blocking serotonin, norepinephrine, dopamine transporters (Ki: 0.14, 54, 3 nM).Formule :C19H23ClN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.87A 77636 hydrochloride
CAS :A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).Formule :C20H28ClNO3Degré de pureté :99.57%Couleur et forme :Yellow SolidMasse moléculaire :365.89ADTN hydrobromide
CAS :ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively).Formule :C10H14BrNO2Couleur et forme :SolidMasse moléculaire :260.13MOR agonist-2
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM.Formule :C37H47Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.71S33084
CAS :S33084 is a potent, selective and competitive antagonist of dopamine D(3)-receptors.Formule :C29H29N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.56Haloperidol D4
CAS :Haloperidol D4 is deuterium-labeled haloperidol.Formule :C21H23ClFNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.89LE 300
CAS :LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formule :C20H22N2Degré de pureté :97.91% - 99.32%Couleur et forme :SolidMasse moléculaire :290.4MOR agonist-3
MOR agonist-3 (Compound 84) is a dual D3R/MOR antagonist with K i values of 382 nM and 55.2 nM, respectively.Couleur et forme :Odour SolidO-2172
CAS :O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).Formule :C14H16Cl2O2Couleur et forme :SolidMasse moléculaire :287.18(R)-Preclamol hydrochloride
CAS :(R)-Preclamol HCl is a dopamine agonist stimulating both auto and postsynaptic receptors.Formule :C14H22ClNOCouleur et forme :SolidMasse moléculaire :255.78Cabergoline
CAS :Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.Formule :C26H37N5O2Degré de pureté :97.69% - 99.86%Couleur et forme :SolidMasse moléculaire :451.6Secretoneurin, rat
CAS :Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).Formule :C159H252N40O58Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3651.95Fluphenazine free base
CAS :Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.Formule :C22H26F3N3OSCouleur et forme :SolidMasse moléculaire :437.52Preclamol hydrochloride
CAS :Preclamol hydrochloride is a selective dopamine autoreceptor agonist. It modulates dopamine release and holds potential for schizophrenia research, utilized in studies concerning dopaminergic signaling and neuropharmacology.Formule :C14H22ClNOCouleur et forme :Yellow SolidMasse moléculaire :255.78ADTN
CAS :ADTN is an agonist of the dopamine receptor.Formule :C10H13NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22Quinelorane
CAS :Quinelorane is dextrorotary isomer.Formule :C14H22N4Couleur et forme :SolidMasse moléculaire :246.35Fenoldopam
CAS :Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).Formule :C16H16ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :305.76N-0500 HCl
CAS :N-0500 HCl, a potent DA receptor agonist, displaces [3H]DP_x005f_x0002_5,6-ADTN with an IC50 of 3nM.Formule :C15H22ClNO2Degré de pureté :98.85% - 99.54%Couleur et forme :White SolidMasse moléculaire :283.79D5R agonist 1
D5R Agonist 1 (Compound 5j) is a selective, orally active partial agonist of the D5 receptor that can penetrate the blood-brain barrier (EC50: 269.7 nM). It has been demonstrated to enhance cognitive abilities in a scopolamine-induced amnesia model.Couleur et forme :Odour Solid
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