GTPase
Les GTPases sont une famille d'enzymes qui hydrolysent le guanosine triphosphate (GTP) en guanosine diphosphate (GDP), jouant un rôle crucial dans les voies de transduction du signal, y compris celles médiées par les GPCR. Les GTPases agissent comme des interrupteurs moléculaires dans divers processus cellulaires, tels que la division cellulaire, la croissance et la différenciation. La dysrégulation de l'activité des GTPases est impliquée dans de nombreuses maladies, y compris le cancer et les troubles génétiques. Chez CymitQuimica, nous offrons une sélection de modulateurs de GTPase de haute qualité pour soutenir vos recherches en signalisation cellulaire, biologie du cancer et voies liées aux GPCR.
23 produits trouvés pour "GTPase"
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PT-129
PT-129 is a PROTAC degrader targeting the NTF2 domain of G3BP1/2, degrading stress granules in stressed cells, suppressing proliferation.Formule :C46H48N8O12SCouleur et forme :SolidMasse moléculaire :936.98RGS2-Galpha-q interaction-IN-1
RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.Formule :C30H30ClN7O3Couleur et forme :SolidMasse moléculaire :572.06Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.Formule :C74H128N16O18Masse moléculaire :1528.95925CID-1067700
CAS :CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formule :C18H18N2O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :390.48Ref: TM-T7558
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg178,00€50mg234,00€100mg303,00€1mL*10mM (DMSO)78,00€Exo-1
CAS :Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, asFormule :C15H12FNO3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :273.26Ref: TM-T9200
5mg52,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€500mg642,00€1mL*10mM (DMSO)65,00€BQU57
CAS :BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formule :C16H13F3N4ODegré de pureté :97.45% - 98.72%Couleur et forme :SolidMasse moléculaire :334.3CCG-50014
CAS :CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.Formule :C16H13FN2O2SDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :316.35Exo1
CAS :Exo1 is an inhibitor of the exocytic pathwayFormule :C15H12FNO3Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :273.26MLS-573151
CAS :MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formule :C21H19N3O2SDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :377.46Ref: TM-T22106
2mg34,00€5mg50,00€10mg86,00€25mg161,00€50mg245,00€100mg363,00€200mg515,00€1mL*10mM (DMSO)55,00€NAV-2729
CAS :NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.Formule :C25H17ClN4O3Degré de pureté :98.83% - 98.91%Couleur et forme :SolidMasse moléculaire :456.88Ref: TM-T5142
2mg43,00€5mg63,00€10mg90,00€25mg193,00€50mg286,00€100mg429,00€500mg888,00€1mL*10mM (DMSO)71,00€RBC8
CAS :RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formule :C25H20N4O3Degré de pureté :98.44% - 99.81%Couleur et forme :SolidMasse moléculaire :424.45Ref: TM-T6634
1mg48,00€5mg92,00€10mg156,00€25mg298,00€50mg472,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)97,00€ML-097
CAS :ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormule :C14H11BrO3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :307.139Ref: TM-T21970
5mg62,00€10mg90,00€25mg133,00€50mg192,00€100mg286,00€500mg687,00€1mL*10mM (DMSO)67,00€Dynamin inhibitory peptide Acetate
Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.Formule :C49H84N18O16Degré de pureté :97.28%Couleur et forme :SolidMasse moléculaire :1181.3Ref: TM-T21798L
1mg73,00€5mg198,00€10mg294,00€25mg467,00€50mg642,00€100mg853,00€1mL*10mM (DMSO)474,00€QS11
CAS :QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.Formule :C36H33N5O2Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :567.68Ref: TM-T4022
2mg34,00€5mg50,00€10mg80,00€25mg147,00€50mg215,00€100mg323,00€200mg442,00€1mL*10mM (DMSO)62,00€Bragsin1
CAS :Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.Formule :C11H6F3NO4Couleur et forme :SolidMasse moléculaire :273.16CCG-4986
CAS :CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein.Formule :C13H11ClN2O5S2Couleur et forme :SolidMasse moléculaire :374.82CCG-2046
CAS :CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.Formule :C11H10N4Couleur et forme :SolidMasse moléculaire :198.22Compound C108
CAS :Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formule :C15H14N2O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :270.28CCG-63802
CAS :CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Formule :C26H18N4O2SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :450.51RBC10
CAS :RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formule :C24H25ClN2O2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :408.92Ref: TM-T24706
1mg33,00€2mg49,00€5mg75,00€10mg110,00€25mg245,00€50mg354,00€100mg515,00€200mg700,00€1mL*10mM (DMSO)81,00€
