Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
708 produits trouvés pour "Synthèse ADN/ARN"
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2'-(2-Nitrobenzyl)-ATP
CAS :<p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>Formule :C17H21N6O15P3Couleur et forme :SolidMasse moléculaire :642.30Polθ-IN-8
CAS :<p>Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.</p>Formule :C22H22ClN7O3SCouleur et forme :SolidMasse moléculaire :499.97(E)-Antiviral agent 67
CAS :<p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.374Polθ-IN-7
CAS :<p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>Formule :C28H35F3N6O2Couleur et forme :SolidMasse moléculaire :544.612AB25583
CAS :<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Formule :C22H17ClN4O3SCouleur et forme :SolidMasse moléculaire :452.91KL-50
CAS :<p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>Formule :C7H7FN6O2Couleur et forme :SolidMasse moléculaire :226.17And1 degrader 1
CAS :<p>And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.</p>Formule :C26H27Cl2N3OCouleur et forme :SolidMasse moléculaire :468.42Uridine 3',5'-diphosphate
CAS :<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Formule :C9H14N2O12P2Couleur et forme :SolidMasse moléculaire :404.16Xanthosine-5'-Triphosphate trisodium
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Formule :C10H12N4Na3O15P3Couleur et forme :SolidMasse moléculaire :590.111LN-439A
CAS :<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Formule :C24H26FN3O4Couleur et forme :SolidMasse moléculaire :439.48N-Nitrosonornicotine
CAS :<p>N-Nitrosonornicotine, a tobacco-specific nitrosamine, exhibits carcinogenic and mutagenic properties, and is capable of inducing micronuclei in C3A cells. Additionally, N-Nitrosonornicotine can form DNA adducts.</p>Formule :C9H11N3OCouleur et forme :SolidMasse moléculaire :177.2GHP-88309
CAS :<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formule :C16H11FN2OCouleur et forme :SolidMasse moléculaire :266.27iPAF1C
CAS :<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Formule :C27H26BrFN4OCouleur et forme :SolidMasse moléculaire :521.42RECTAS-2.0
CAS :<p>RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G>A mutation, intended for research in Fabry disease.</p>Formule :C18H17ClN4O4Couleur et forme :SolidMasse moléculaire :388.805GR 122222X
CAS :<p>GR 122222X is an inhibitor of topoisomerase II.</p>Formule :C26H35N5O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.65PolQi1
CAS :<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Formule :C18H14ClF5N4O2Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :448.77Epolactaene
CAS :<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44(Rac)-Plevitrexed
CAS :<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53VPC-80051
CAS :<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formule :C16H13F2N3OCouleur et forme :SolidMasse moléculaire :301.291CTPS1-IN-1
CAS :<p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>Formule :C21H22N6O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :486.57
