Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
710 produits trouvés pour "Synthèse ADN/ARN"
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TDRL-551
CAS :TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18 µM) with potential anticancer activity.TDRL-551 inhibits RPA-DNA interaction andFormule :C25H23ClIN3O4Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :591.83Enocitabine
CAS :<p>Enocitabine is a nucleoside analog.</p>Formule :C31H55N3O6Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :565.78ERCC1-XPF-IN-1
CAS :<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Formule :C28H32ClN5O2Couleur et forme :SolidMasse moléculaire :506.04cp028
CAS :<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Formule :C23H17FN2O4Couleur et forme :SolidMasse moléculaire :404.39Apricitabine
CAS :<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Formule :C8H11N3O3SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :229.26HBV-IN-14
CAS :<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87AS-136A
CAS :<p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>Formule :C17H19F3N4O3SDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :416.42BMVC2
CAS :<p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>Formule :C28H25I2N3Couleur et forme :SolidMasse moléculaire :657.33IACS-4759
CAS :<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Formule :C10H17N3O2Couleur et forme :SolidMasse moléculaire :211.26MMV688845
CAS :<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Formule :C24H25N3O3SCouleur et forme :SolidMasse moléculaire :435.54Antibacterial agent 124
CAS :<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Formule :C16H17ClFN3O2Couleur et forme :SolidMasse moléculaire :337.78CB 3717
CAS :<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Formule :C24H23N5O6Couleur et forme :SolidMasse moléculaire :477.472-Fluoroadenine
CAS :<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Formule :C5H4FN5Degré de pureté :98.84% - 99.62%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :153.12Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Formule :C24H33N7Couleur et forme :SolidMasse moléculaire :419.57HBV-IN-15
CAS :<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Formule :C24H23ClO6Couleur et forme :SolidMasse moléculaire :442.89D-I03
CAS :<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Formule :C23H36N6SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :428.64DDRI-18
CAS :<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Formule :C26H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.48RP-6685
CAS :<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Formule :C22H14F7N5ODegré de pureté :99.65%Couleur et forme :SoildMasse moléculaire :497.37Cytembena
CAS :<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Formule :C11H8BrNaO4Degré de pureté :99.35%Couleur et forme :White PowderMasse moléculaire :307.07ERCC1-XPF-IN-2
CAS :<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formule :C15H13Cl2NO3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :326.176-Hydroxy-DOPA
CAS :<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Formule :C9H11NO5Degré de pureté :97.78% - 97.95%Couleur et forme :SolidMasse moléculaire :213.19116-9e
CAS :<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Formule :C31H32N2O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :512.6SMN-C2
CAS :<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formule :C24H27N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :417.5ZIM
CAS :<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Formule :C20H19N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :349.38Talviraline
CAS :<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Formule :C15H20N2O3S2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :340.46Galocitabine
CAS :<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Formule :C19H22FN3O8Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :439.39Caracemide
CAS :<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Formule :C6H11N3O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :189.17TTP-8307
CAS :TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Formule :C27H21FN4ODegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :436.48CHD1Li 6.11
CAS :<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Formule :C21H22BrN5OSDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :472.4Anticancer agent 73
CAS :<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Formule :C14H15NO4Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :261.279-Deazaguanine
CAS :<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Formule :C6H6N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :150.14DNA polymerase-IN-3
CAS :<p>DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in</p>Formule :C13H12O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.233-Cyanovinylcarbazole phosphoramidite
CAS :<p>3-Cyanovinylcarbazole phosphoramidite: an antiviral, hinders viral DNA synthesis, modifies ribonucleotides.</p>Formule :C50H53N4O6PCouleur et forme :SolidMasse moléculaire :836.95Votoplam
CAS :<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Formule :C21H25N9ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.485,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS :<p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Formule :C21H26N6O6Couleur et forme :SolidMasse moléculaire :458.475-DACTHF
CAS :<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Formule :C19H24N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.43Diazoketone methotrexate
CAS :<p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>Formule :C21H22N10O4Couleur et forme :SolidMasse moléculaire :478.46TAS-114
CAS :<p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>Formule :C21H29N3O6SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :451.54WRN inhibitor 4
CAS :<p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formule :C16H14N2O5SCouleur et forme :SolidMasse moléculaire :346.36UNC-2170
CAS :<p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>Formule :C14H21BrN2ODegré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :313.23WRN inhibitor 3
CAS :<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formule :C20H20N2O5SCouleur et forme :SolidMasse moléculaire :400.45BVDU 5′-Triphosphate
CAS :<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Formule :C11H16BrN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.088-Azahypoxanthine
CAS :<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Formule :C4H3N5ODegré de pureté :99.66%Couleur et forme :Light Yellow To Light Beige Fine CrystallineMasse moléculaire :137.1WRN inhibitor 1
CAS :<p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>Formule :C16H13FN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.35UNC2170 maleate
CAS :<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Formule :C14H21BrN2OC4H4O4Couleur et forme :SolidMasse moléculaire :429.31DAM-IN-1
CAS :<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Formule :C16H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.31Pencitabine
CAS :<p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>Formule :C15H20F3N3O6Couleur et forme :SolidMasse moléculaire :395.33COH1
CAS :<p>COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].</p>Formule :C11H10N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :250.27WRN inhibitor 2
CAS :<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Formule :C15H11F3N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38H3B-968
CAS :<p>H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease</p>Formule :C22H18F6N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.46
