Antibiotique

Farinomalein A, a maleimide derivative, is isolated from the entomopathogenic fungus Paecilomyces farinosus. It exhibits effective inhibitory activity against soybean pathogen Phytophtora sojae.

TNKS-2-IN-1 inhibits TNKS1/2 (IC50: 259/1100 nM), has antimicrobial effects on E. coli/S. aureus, and blocks NLRP3/IL-1β release (IC50: 5 μM).

Viridicatin is a natural product for research related to life sciences. The catalog number is T38335 and the CAS number is 129-24-8.

Cladospirone bisepoxide, a fungal metabolite, is a selective antibiotic that also hinders L. sativum germination.

Bleomycin B4 (Phleomycin F), an antibiotic with antitumor properties, is utilized in cancer research [1] [2] [3].

Distamycin A (NSC-82150), oligopeptide antibiotic, binds A/T rich DNA, affects cleavage sites, enhances apoptosis.

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 [1] .

Bibrocathol is a well-established antiseptic drug used for the treatment of acute eyelid diseases like blepharitis.

Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.

<p>Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, effectively inhibits chitin synthetase.</p>

Mandipropamid specifically induces complex formation between PYR1 and abscisic acid-insensitive hexameric mutants.

<p>Protorubradirin is an antibiotic that can be isolated from the non-pigmented Streptomyces achromogenes var. rubradiris alongside Rubradirin. It exhibits inhibitory activity against HIV reverse transcriptase. In vitro studies show that Protorubradirin also inhibits strains of Staphylococcus aureus and Streptococcus. In infected mice, subcutaneous administration of Protorubradirin demonstrates in vivo efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may significantly reduce its activity compared to Rubradirin, possibly due to its C-nitroso sugar decomposing more rapidly in acidic gastric conditions.</p>

<p>Eravacycline HCl (TP-434 HCl) is potent antibiotic with broad-spectrum antibacterial activity.</p>

Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.

Zegruvirimat is an antiviral agent. Zegruvirimat has antiviral activity [1] .

<p>Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.</p>

<p>FR901379, an echinocandin-like antifungal, combats various fungi, protects mice from C. albicans, and lessens P. carinii infection symptoms.</p>

Antibiotic WB is a useful organic compound for research related to life sciences. The catalog number is T125208 and the CAS number is 247919-66-0.

Venturicidin A is a macrolide antibiotic.