Protéase du VIH
Les inhibiteurs de la protéase du VIH sont une classe de médicaments antirétroviraux qui ciblent spécifiquement l'enzyme protéase du virus de l'immunodéficience humaine (VIH). En inhibant cette enzyme, ces composés empêchent le virus de transformer ses polyprotéines en protéines matures et fonctionnelles, bloquant ainsi la production de nouveaux virions infectieux. Les inhibiteurs de la protéase du VIH constituent une pierre angulaire de la thérapie antirétrovirale hautement active (HAART) utilisée pour gérer le VIH/SIDA. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la protéase du VIH pour soutenir votre recherche sur le traitement du VIH, la résistance médicamenteuse et la virologie.
478 produits trouvés pour "Protéase du VIH".
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Nevirapine
CAS :Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Formule :C15H14N4ODegré de pureté :99.58% - 99.59%Couleur et forme :SolidMasse moléculaire :266.30(Rac)-Telinavir
CAS :N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.
Formule :C33H44N6O5Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :604.74GSK2838232
CAS :GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.Formule :C48H73ClN2O6Degré de pureté :97.97%Couleur et forme :SolidMasse moléculaire :809.56Ref: TM-T15436
1mg56,00€5mg118,00€1mL*10mM (DMSO)170,00€10mg178,00€25mg375,00€50mg528,00€100mg737,00€Dolutegravir intermediate-1
CAS :Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Formule :C13H17NO8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :315.28Clathrin-IN-1
CAS :Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.Formule :C20H13BrN2O3S2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :473.36Ref: TM-T9063
1mg50,00€2mg73,00€5mg90,00€1mL*10mM (DMSO)105,00€10mg141,00€25mg245,00€50mg358,00€100mg530,00€500mg1.153,00€Salicylanilide
CAS :Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.Formule :C13H11NO2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :213.23Ibalizumab
CAS :Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4Degré de pureté :SDS-PAGE:96.4%;SEC-HPLC:97.7%Couleur et forme :Transparent LiquidMasse moléculaire :147.3 kDaRitonavir
CAS :Ritonavir (ABT 538) inhibits HIV-1/2 proteases; serum proteins limit it but it enhances other HIV drugs by hindering P450 degradation.Formule :C37H48N6O5S2Degré de pureté :99.38% - 99.96%Couleur et forme :White PowderMasse moléculaire :720.94Ref: TM-T1525
5mg34,00€10mg50,00€1mL*10mM (DMSO)50,00€25mg74,00€50mg96,00€100mg138,00€200mg192,00€500mg321,00€1g475,00€PF-3450074
CAS :PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Formule :C27H27N3O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :425.52(S)-(+)-N-3-Benzylnirvanol
CAS :(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.Cost-effective and quality-assured.Formule :C18H18N2O2Degré de pureté :98.90%Couleur et forme :White SolidMasse moléculaire :294.35Elsulfavirine
CAS :Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.Formule :C24H17BrCl2FN3O5SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :629.28Ref: TM-T15210
1mg69,00€5mg147,00€1mL*10mM (DMSO)200,00€10mg230,00€25mg462,00€50mg692,00€100mg973,00€Atazanavir sulfate
CAS :Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.Formule :C38H52N6O7·H2SO4Degré de pureté :99.31% - 99.40%Couleur et forme :SolidMasse moléculaire :802.93Ref: TM-T0100
5mg44,00€1mL*10mM (DMSO)50,00€10mg58,00€25mg90,00€50mg114,00€100mg170,00€200mg250,00€500mg425,00€Fostemsavir Tris
CAS :Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment.Formule :C29H37N8O11PDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :704.62Ref: TM-T10570
1mg54,00€5mg114,00€10mg167,00€1mL*10mM (DMSO)170,00€25mg268,00€50mg409,00€100mg580,00€Sodium copper chlorophyllin B
CAS :Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV.Formule :C34H29CuN4Na3O7Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :738.13Pepstatin
CAS :Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formule :C34H63N5O9Degré de pureté :96.74% - 99.94%Couleur et forme :SolidMasse moléculaire :685.89Benfotiamine
CAS :Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.Formule :C19H23N4O6PSDegré de pureté :99.2% - 99.91%Couleur et forme :White SolidMasse moléculaire :466.45Atazanavir
CAS :Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.Formule :C38H52N6O7Degré de pureté :98% - 99.95%Couleur et forme :Crystalline SolidMasse moléculaire :704.86NBD-556
CAS :NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.Formule :C17H24ClN3O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :337.84TERT-IN-1
CAS :TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.Formule :C16H20ClN3SDegré de pureté :99.31%Couleur et forme :Yellow SolidMasse moléculaire :321.87HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Couleur et forme :Odour SolidHIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormule :C26H24N6O2Couleur et forme :SolidMasse moléculaire :452.51Aureothin
CAS :Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Formule :C22H23NO6Couleur et forme :SolidMasse moléculaire :397.42TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formule :C65H124N34O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1621.91Peptide T TFA
CAS :Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Formule :C37H56F3N9O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :971.89HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Formule :C42H36ClF10N7O5S2Couleur et forme :SolidMasse moléculaire :1008.35HIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Formule :C32H44N2O8SCouleur et forme :SolidMasse moléculaire :616.77HIV gag peptide (197-205)
CAS :HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFormule :C45H81N11O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1064.32HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formule :C28H31N9O2SCouleur et forme :SolidMasse moléculaire :557.67HIV p17 Gag (77-85)
CAS :Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formule :C44H72N10O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.1Tipranavir
CAS :Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzymeFormule :C31H33F3N2O5SDegré de pureté :99.85%Couleur et forme :White SolidMasse moléculaire :602.66Ref: TM-T4578
1mg69,00€5mg147,00€1mL*10mM (DMSO)192,00€10mg260,00€25mg580,00€50mg888,00€100mg1.485,00€200mg2.008,00€Kni 102
CAS :Kni 102 is a biochemical.Formule :C31H41N5O7Couleur et forme :SolidMasse moléculaire :595.69ICeD-2
ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.Formule :C20H29N3OCouleur et forme :SolidMasse moléculaire :327.46L 754394
CAS :L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formule :C38H47N5O5Couleur et forme :SolidMasse moléculaire :653.81AL-470
CAS :AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormule :C67H57N7O23Couleur et forme :SolidMasse moléculaire :1328.2HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormule :C23H40O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.56HIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Formule :C28H28FN5O3SCouleur et forme :SolidMasse moléculaire :533.62Bictegravir Sodium
CAS :Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formule :C21H17F3N3NaO5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :471.36GRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Couleur et forme :Odour SolidNNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formule :C32H31N9O3SCouleur et forme :SolidMasse moléculaire :621.71MPG, HIV related
CAS :MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formule :C126H201N35O33SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2766.22HIV-1-IN-83
HIV-1-IN-83 (Compound 18E) is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It demonstrates an IC50 of 0.45 μM against wild-type HIV-1 reverse transcriptase. HIV-1-IN-83 exhibits potent antiviral activity against both wild-type and mutant HIV-1 strains and enhances drug resistance in Y188L and RES056 mutants. The compound is non-toxic up to a concentration of 11.088 μM.Couleur et forme :Odour SolidCys-TAT(47-57)
CAS :Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formule :C67H124N34O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1661.99HIV-1 inhibitor-79
HIV-1inhibitor-79 (Compound 3k) is an HIV inhibitor that demonstrates significant inhibitory activity against HIV-1 and its common mutants, with IC50 values of 1.9 nM for HIV-1, K103, 8.7 nM for L100I, and 11 nM for E138K. It exhibits low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478). Additionally, HIV-1inhibitor-79 shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and effectively inhibits HIV-1 reverse transcriptase with an IC50 of 25 nM.Formule :C21H17N7OMasse moléculaire :383.41Carbovir triphosphate
CAS :Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Formule :C11H16N5O11P3Couleur et forme :SolidMasse moléculaire :487.19GLR-19
CAS :GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formule :C102H194N40O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2300.89Globotriaosylceramides (porcine)
CAS :Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formule :C60H113NO18Couleur et forme :SolidMasse moléculaire :1136.553HIV-IN-12
HIV-IN-12 (Compound A1) is a dual inhibitor targeting both HIV-1 Vif and reverse transcriptase (RT). It shows potential for use in HIV infection research.F9170 TFA
F9170, an antiviral peptide derived from the HIV-1 envelope glycoprotein (amino acids 789-803), targets the LLP1 domain in the virus's envelope proteinFormule :C100H135N21O22·XCF3COOHMasse moléculaire :1983.30NNRT-IN-11
NNRT-IN-11 (14l) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor, exhibiting EC50 values ranging from 6.50 to 52.9 nM against both wild-type (WT) and a range of HIV-1 mutant strains. NNRT-IN-11 demonstrates antiviral properties.Couleur et forme :Odour SolidClavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFormule :C20H28O3Couleur et forme :SolidMasse moléculaire :316.43
