Protéase du VIH
Les inhibiteurs de la protéase du VIH sont une classe de médicaments antirétroviraux qui ciblent spécifiquement l'enzyme protéase du virus de l'immunodéficience humaine (VIH). En inhibant cette enzyme, ces composés empêchent le virus de transformer ses polyprotéines en protéines matures et fonctionnelles, bloquant ainsi la production de nouveaux virions infectieux. Les inhibiteurs de la protéase du VIH constituent une pierre angulaire de la thérapie antirétrovirale hautement active (HAART) utilisée pour gérer le VIH/SIDA. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la protéase du VIH pour soutenir votre recherche sur le traitement du VIH, la résistance médicamenteuse et la virologie.
449 produits trouvés pour "Protéase du VIH"
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SPD-756
CAS :<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formule :C12H16N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.29NNRT-IN-6
<p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>Formule :C32H31N9O3SCouleur et forme :SolidMasse moléculaire :621.71Aureothin
CAS :<p>Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>Formule :C22H23NO6Couleur et forme :SolidMasse moléculaire :397.42HIV-1 inhibitor-80
<p>HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.</p>Formule :C26H19N7OCouleur et forme :SolidMasse moléculaire :445.475Bictegravir Sodium
CAS :<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Formule :C21H17F3N3NaO5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :471.36CI-39
CAS :<p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.</p>Formule :C19H18N2O4Couleur et forme :SolidMasse moléculaire :338.36Indoline
CAS :<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C8H9NCouleur et forme :Clear To Yellow LiquidMasse moléculaire :119.16(-)-Rabdosiin
CAS :<p>(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].</p>Formule :C36H30O16Couleur et forme :SolidMasse moléculaire :718.61HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Couleur et forme :Odour SolidHIV-IN-2
CAS :<p>HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].</p>Formule :C34H27ClF7N9O3SCouleur et forme :SolidMasse moléculaire :810.144-Deoxy-4α-phorbol
CAS :<p>4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E.</p>Formule :C20H28O5Couleur et forme :SolidMasse moléculaire :348.43JE-2178
CAS :<p>JE-2178 is compound with high bioavailability .</p>Formule :C35H51N5O6SCouleur et forme :SolidMasse moléculaire :669.87Hinnuliquinone
CAS :Hinnuliquinone is an anti-HIV agent.Formule :C32H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.59ICeD-2
<p>ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.</p>Formule :C20H29N3OCouleur et forme :SolidMasse moléculaire :327.46Elvucitabine
CAS :<p>Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.</p>Formule :C9H10FN3O3Couleur et forme :SolidMasse moléculaire :227.19Clavirolide L
<p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>Formule :C20H28O3Couleur et forme :SolidMasse moléculaire :316.43RPR103611
CAS :<p>RPR103611, a betulinic acid derivative, inhibits HIV-1; IC50s: CCR5 (YU2) 80, CXCR4 (NL4-3) 0.27, dual-tropic (89.6) 0.17.</p>Formule :C46H78N2O6Couleur et forme :SolidMasse moléculaire :755.12Decanoyl-RVKR-CMK TFA
CAS :<p>Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.</p>Formule :C36H67ClF3N11O7Couleur et forme :SolidMasse moléculaire :858.45Emtricitabine S-oxide
CAS :<p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>Formule :C8H10FN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :263.25(+)-Carbovir triphosphate
CAS :<p>(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.</p>Formule :C11H16N5O11P3Couleur et forme :SolidMasse moléculaire :487.19TAT peptide
<p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>Formule :C65H124N34O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1621.91HIV-1 protease-IN-4
<p>HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.</p>Formule :C48H69N7O11Couleur et forme :SolidMasse moléculaire :920.1JE-2147
CAS :<p>JE-2147: a hybrid peptide with multiple amino acid types linked by peptide bonds.</p>Formule :C32H37N3O5SCouleur et forme :SolidMasse moléculaire :575.72GLR-19
CAS :<p>GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].</p>Formule :C102H194N40O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2300.89HIV-1 protease-IN-10
<p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>Formule :C23H40O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.56Alvircept sudotox
CAS :<p>Alvircept sudotox, a recombinant CD4 fused with exotoxin A from Pneumonas aeruginosa, is utilized in HIV infection research [1].</p>Couleur et forme :LiquidCarbovir triphosphate
CAS :<p>Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].</p>Formule :C11H16N5O11P3Couleur et forme :SolidMasse moléculaire :487.19Kni 102
CAS :<p>Kni 102 is a biochemical.</p>Formule :C31H41N5O7Couleur et forme :SolidMasse moléculaire :595.69Lopinavir Metabolite M-1
CAS :<p>Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.</p>Formule :C37H46N4O6Couleur et forme :SolidMasse moléculaire :642.78Scirpusin A
CAS :<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Formule :C28H22O7Couleur et forme :SolidMasse moléculaire :470.47NF279
CAS :<p>P2X1 antagonist</p>Formule :C49H36N6Na6O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1407.17HIV-1 inhibitor-59
<p>HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.</p>Formule :C28H28FN5O3SCouleur et forme :SolidMasse moléculaire :533.62QYL-685
CAS :<p>QYL-685 is a methylenecyclopropane nucleoside analog.</p>Formule :C20H24N7O5PCouleur et forme :SolidMasse moléculaire :473.42Delavirdine
CAS :<p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>Formule :C22H28N6O3SCouleur et forme :SolidMasse moléculaire :456.56Hypoglaunine D
CAS :<p>Hypoglaunine D, an anti-HIV analogue of Triptonine B, inhibits HIV in H9 cells with an EC50 of 22 μg/ml.</p>Formule :C41H47NO19Couleur et forme :SolidMasse moléculaire :857.81HIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Couleur et forme :Odour SolidKadsuralignan A
CAS :<p>Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an</p>Formule :C22H26O7Couleur et forme :SolidMasse moléculaire :402.44MB-66
<p>MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour LiquidCys-TAT(47-57)
CAS :<p>Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.</p>Formule :C67H124N34O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1661.99HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Formule :C26H24N6O2Couleur et forme :SolidMasse moléculaire :452.5112-Oxocalanolide A
<p>12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.</p>Formule :C22H24O5Couleur et forme :SolidMasse moléculaire :368.429Salvianan A
CAS :<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Formule :C20H17NO2Couleur et forme :SolidMasse moléculaire :303.35Amdoxovir
CAS :<p>Amdoxovir is a reverse transcriptase inhibitor.</p>Formule :C9H12N6O3Couleur et forme :SolidMasse moléculaire :252.23HIV gag peptide (197-205)
CAS :<p>HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI</p>Formule :C45H81N11O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1064.32MPG, HIV related
CAS :<p>MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.</p>Formule :C126H201N35O33SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2766.22Kuguacin N
<p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>Formule :C30H46O4Couleur et forme :SolidMasse moléculaire :470.694Peptide T TFA
CAS :<p>Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.</p>Formule :C37H56F3N9O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :971.89Peptide T
CAS :<p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>Formule :C35H55N9O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :857.86HIV-1 inhibitor-81
<p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>Formule :C32H44N2O8SCouleur et forme :SolidMasse moléculaire :616.77Globotriaosylceramides (porcine)
CAS :<p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>Formule :C60H113NO18Couleur et forme :SolidMasse moléculaire :1136.553
