Protéase du VIH
Les inhibiteurs de la protéase du VIH sont une classe de médicaments antirétroviraux qui ciblent spécifiquement l'enzyme protéase du virus de l'immunodéficience humaine (VIH). En inhibant cette enzyme, ces composés empêchent le virus de transformer ses polyprotéines en protéines matures et fonctionnelles, bloquant ainsi la production de nouveaux virions infectieux. Les inhibiteurs de la protéase du VIH constituent une pierre angulaire de la thérapie antirétrovirale hautement active (HAART) utilisée pour gérer le VIH/SIDA. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la protéase du VIH pour soutenir votre recherche sur le traitement du VIH, la résistance médicamenteuse et la virologie.
449 produits trouvés pour "Protéase du VIH"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
HIV p17 Gag (77-85)
CAS :<p>Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.</p>Formule :C44H72N10O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.1Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS :<p>Tenofovir-C3-O-C12 has a longer half-life, potent anti-HIV effects, and better pharmacokinetics than tenofovir.</p>Formule :C29H55N6O5PSiCouleur et forme :SolidMasse moléculaire :626.855SPD-756
CAS :<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formule :C12H16N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.29Scirpusin A
CAS :<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Formule :C28H22O7Couleur et forme :SolidMasse moléculaire :470.47HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Formule :C26H24N6O2Couleur et forme :SolidMasse moléculaire :452.51Salvianan A
CAS :<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Formule :C20H17NO2Couleur et forme :SolidMasse moléculaire :303.35BMS-955176 TFA
CAS :<p>GSK3532795: Oral HIV-1 maturation inhibitor, broad virus coverage, EC50: 15 nM, good preclinical pharmacokinetics.</p>Formule :C44H64N2O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :781.06Kadsuralignan A
CAS :<p>Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an</p>Formule :C22H26O7Couleur et forme :SolidMasse moléculaire :402.44HIV-IN-2
CAS :<p>HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].</p>Formule :C34H27ClF7N9O3SCouleur et forme :SolidMasse moléculaire :810.14Clavirolide L
<p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>Formule :C20H28O3Couleur et forme :SolidMasse moléculaire :316.43Bictegravir Sodium
CAS :<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Formule :C21H17F3N3NaO5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :471.36(2S,5S)-Censavudine
<p>(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.</p>Formule :C12H12N2O4Couleur et forme :SolidMasse moléculaire :248.23UK-88947 HCl
CAS :<p>UK 88947 is a protease inhibitor.</p>Formule :C41H63ClN6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.44MPG, HIV related
CAS :<p>MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.</p>Formule :C126H201N35O33SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2766.22Elvucitabine
CAS :<p>Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.</p>Formule :C9H10FN3O3Couleur et forme :SolidMasse moléculaire :227.19BNM-III-170
CAS :<p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>Formule :C25H26ClF7N6O6Couleur et forme :SolidMasse moléculaire :674.96N36Mut(e,g)
<p>N36Mut(e,g) is an HIV fusion peptide inhibitor targeting gp41. It functions by disrupting the formation of the homotrimeric coiled coil of the N-terminal helix in the pre-hairpin intermediate, leading to the creation of a heterotrimer.</p>Formule :C189H317N55O56Couleur et forme :SolidMasse moléculaire :4255.87PROTAC Vif degrader-1
<p>PROTACVif degrader-1 (Compound L15) is a Vif-targeted PROTAC degrader exhibiting anti-HIV-1 virucidal activity, with an EC50 of 33.35 μM against HIV-1IIIB.</p>Couleur et forme :Odour SolidHIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Couleur et forme :Odour SolidIndoline
CAS :<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C8H9NCouleur et forme :Clear To Yellow LiquidMasse moléculaire :119.16Pol (476-484), HIV-1 RT Epitope
CAS :<p>Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (</p>Formule :C46H78N12O12Couleur et forme :SolidMasse moléculaire :991.18[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)
CAS :[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].Formule :C76H108N14O26SCouleur et forme :SolidMasse moléculaire :1665.81NF279
CAS :<p>P2X1 antagonist</p>Formule :C49H36N6Na6O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1407.17VIR-165
<p>VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.</p>Formule :C109H158N22O25S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2240.7GP120, HIV-1 MN
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2].Formule :C135H221N45O33Couleur et forme :SolidMasse moléculaire :3002.5Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2
CAS :<p>Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2, a peptide substrate for HIV-1 protease, is used in inhibition assays.</p>Formule :C38H58N10O12Couleur et forme :SolidMasse moléculaire :846.93Peptide T
CAS :<p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>Formule :C35H55N9O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :857.86Interiorin
CAS :<p>Interiorin, extracted from Kadsura heteroclita, exhibits moderate anti-HIV activity, exhibiting an EC_50 of 1.6 μg/mL [1].</p>Formule :C27H30O8Couleur et forme :SolidMasse moléculaire :482.52Amdoxovir
CAS :<p>Amdoxovir is a reverse transcriptase inhibitor.</p>Formule :C9H12N6O3Couleur et forme :SolidMasse moléculaire :252.23HIV-1 inhibitor-75
<p>HIV-1inhibitor-75 is a human immunodeficiency virus 1 (HIV-1) inhibitor with an EC50 range of 0.0039-0.338 μM. Its target is the reverse transcriptase, exhibiting an IC50 value of 0.055 μM. Additionally, HIV-1inhibitor-75 demonstrates good metabolic stability in vitro, presenting moderate clearance rates and an extended half-life in human plasma and liver microsomes.</p>Formule :C25H20ClN3O3SCouleur et forme :SolidMasse moléculaire :477.96Globotriaosylceramides (porcine)
CAS :<p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>Formule :C60H113NO18Couleur et forme :SolidMasse moléculaire :1136.553Enfuvirtide
CAS :<p>Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.</p>Formule :C204H301N51O64Degré de pureté :98%Couleur et forme :White To Off-White Amorphous SolidMasse moléculaire :4491.9454-Acetylbutyric acid
CAS :<p>4-Acetylbutyric acid is a ketone acid widely used in biochemical experiments and drug synthesis research.</p>Formule :C6H10O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :130.14CI-39
CAS :<p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.</p>Formule :C19H18N2O4Couleur et forme :SolidMasse moléculaire :338.36NNRTIs-IN-3
<p>NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 µM [1].</p>Formule :C17H20ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.83Aureothin
CAS :<p>Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>Formule :C22H23NO6Couleur et forme :SolidMasse moléculaire :397.42(±)-BI-D
CAS :<p>(±)-BI-D is an effective ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site (IC50: 2.4–2.9 μM).</p>Formule :C25H27NO4Couleur et forme :SolidMasse moléculaire :405.49Saquinavir mesylate
CAS :<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Formule :C39H54N6O8SDegré de pureté :99.19%Couleur et forme :White Or Pale Yellow PowderMasse moléculaire :766.9Dideoxyadenosine
CAS :<p>2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].</p>Formule :C10H13N5O2Degré de pureté :99.28%Couleur et forme :Physical Description Off-White Powder (Ntp 1992)Masse moléculaire :235.242'-Deoxy-2'-fluoroarabinoadenosine
CAS :<p>2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.</p>Formule :C10H12FN5O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :269.23Pseudothymidine
CAS :<p>Pseudothymidine is a C-nucleoside analog of thymidine.</p>Formule :C10H14N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.23Pentosan Polysulfate Sodium (W/W 43%)
CAS :<p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/A(Z)-9-Propenyladenine
CAS :<p>(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.</p>Formule :C8H9N5Couleur et forme :SolidMasse moléculaire :175.19TAT (48-57)
CAS :<p>TAT (48-57) is a cell-permeable HIV-1 Tat protein fragment, amino acids 48-57.</p>Formule :C55H109N31O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1396.65Abacavir hydroxyacetate
CAS :<p>Abacavir hydroxyacetate is a nucleoside analog reverse transcriptase inhibitor used in the study of HIV infection.</p>Formule :C16H20N6O3Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :344.37gardiquimod TFA salt
CAS :<p>Gardiquimod diTFA is a TLR7/8 agonist that may block HIV-1 in macrophages and PBMCs, active under 10 μM.</p>Formule :C21H25F6N5O5Couleur et forme :SolidMasse moléculaire :541.44Tenofovir hydrate
CAS :<p>Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.</p>Formule :C9H16N5O5PDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :305.23Letrazuril
CAS :<p>Letrazuril is a compound of the anti-HIV.</p>Formule :C17H9Cl2FN4O2Couleur et forme :SolidMasse moléculaire :391.18Etravirine D4
CAS :<p>Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.</p>Formule :C20H15BrN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.3Cabotegravir sodium
CAS :<p>Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.</p>Formule :C19H16F2N3NaO5Couleur et forme :SolidMasse moléculaire :427.34
![[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2519.webp&w=3840&q=75)
