Antibactérien

Citromycetin, a fungal metabolite, has antibiotic effects on V. cholerae, S. flexneri, and S. aureus.

MF 961 is a quinolone bactericide. It exhibits MIC50 values in the range of 0-25 mg/L against E. coli, Klebsiella sp., Enterobacter sp., Citrobacter sp., and Shigella sp.

Impurity B in Cefpodoxime Proxetil, a broad-spectrum oral antibiotic, is a third-generation cephalosporin.

Orazamide may be useful to treat chronic hepatitis and various skin diseases.

Cellocidin inhibits gammaherpesvirus-related B-lymphoma growth via NF-κB and c-Myc pathways.

Desferriferribactin is a biogenetic precursor of pyoverdin.

Tibezonium iodide, an oropharyngeal disinfectant, possesses antibacterial properties that aid in preventing mouth infections [1].

Compound 5a: MICs of 25, 25, 50, 50 μg/mL vs. B. subtilis, S. aureus, P. aeruginosa, E. coli.

Antimycobacterial agent-10 (compound 5) is an inhibitor of DNA gyrase with an IC50 of 96 nM against Mycobacterium tuberculosis gyrase, demonstrating antibacterial properties.

Sperabillin C is a potent antibacterial antibiotic in vivo isolated from Pseudomonas fluorescens YK-437.

"Antibacterial Synergist 2 inhibits biofilms of S. enterica, S. aureus, P. aeruginosa, and C. albicans."

LtaS-IN-2 (compound 13), a derivative of LtaS-IN-1 [1], is an LTA synthesis inhibitor with antibacterial properties against S.

Hexylene glycol (Diolane), colorless liquid, is a chiral diol. It is an industrial compound produced from diacetone alcohol by hydrogenation.

Flambalactone is a degradation product formed by methanolysis of the antibiotic flambamycin.

VEGFR-2/InhA-IN-1, a dual inhibitor based on pyrazole, targets InhA and VEGFR, exhibiting both anti-tuberculosis and anti-angiogenic properties. It demonstrates effective antibacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC = 6.25 μg/mL) and significantly suppresses VEGFR-2 activity (IC 50 = 15.27 nM).

Flambamycin is an antibiotic isolated from Streptomyces hygroscopicus.

Janthinocin B is a novel macrocyclic peptide lactone antibiotic.

ω-azido-C6 Ceramide reduces membrane potential and exhibits antibacterial activity against Neisseria, with a minimum inhibitory concentration (MIC) of 2 µg/mL for N. meningitidis MC58 and N. gonorrhoeae FA1090.

Antibacterial agent 246 (compound A33) demonstrates a minimum inhibitory concentration (MIC) ranging from 0.5 to 4 μg/mL against 23 species of Gram-positive bacteria. When used in combination with Polymyxin E, it inhibits the growth of various Gram-negative bacteria, showing a partial inhibitory concentration index of 0.066.

Protactin, a new antibiotic metabolite, is a possible precursor of the actinomycins.

Chitinase, found in bacteria, fungi, animals, plants, is a glycosyl hydrolase that hydrolyzes chito-oligosaccharides.

Monensin sodium salt (Standard) is the standard substance of Monensin sodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion

Triclosan-methyl, derived from bactericidal triclosan, is used in toothpaste, shampoos, soaps, detergents, and cosmetics.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.

Troleandomycin is a macrolide antibiotic and is similar to Erythromycin.

Acyclovir (Aciclovir) hydrochloride is an effective oral antiviral agent with potent anti-herpetic activity. It exhibits IC50 values of 0.85 μM for HSV-1 and 0.86 μM for HSV-2, indicating strong inhibitory effects against these strains. Additionally, Acyclovir hydrochloride induces cell cycle disturbances and apoptosis. This compound also prevents bacterial infections during induction therapy for acute leukemia.

Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.

Cefalexin hydrochloride is a cephalosporin antibiotic.

Sulfisoxazole (Standard) is the standard substance of Sulfisoxazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A.

Avibactam free acid is a potent β-lactamase inhibitor exhibiting covalent and reversible properties, capable of inhibiting TEM-1, P99, and CTX-M-15.

Dibenzylideneacetone is a synthetic curcumin analog. It leads to apoptotic cell death in Leishmania donovani.

Sulfaclozine sodium: antibacterial, anticoccidial sulphonamide for poultry disease treatment.

G907 is an antagonist of the ATP-binding cassette (ABC) transporter protein MsbA with bactericidal activity. G907 inhibits MsbA in E. coli.

Quaternium 12, a bactericidal, virucidal, and fungicidal compound used in many products.

Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.

Iron (III) hexacyanoferrate (II) is a useful organic compound for research related to life sciences.

Deshydroxyethoxy ticagrelor (AR-C124910) is a metabolite of Ticagrelor that exhibits antibacterial activity against MRSA and possesses antiplatelet effects.

IMB-808 is an LXRα/β dual agonist that promotes ABCA1 expression and cholesterol efflux, used in atherosclerosis research.

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

2-Cyclopentenone can inhibit the activity of HepG2 cells and has inhibitory activity against urease in Sporosarcina pasteurii.

OES2-0017 exhibits strong synergistic effects and growth inhibition in collaboration with polyamines within a low micromolar range. At low concentrations, OES2-0017 inhibits spermidine/spermine N1-acetyltransferase (SpeG) (IC50: 34.82 μM) and other polyamine detoxifying enzymes, while at higher concentrations, it disrupts bacterial membranes.

Pivampicillin, a pivalate ester analog of Ampicillin, is used to treat chronic obstructive pulmonary disease (COPD) in children and young adults.

EDTA disodium dihydrate chelates metals, inhibits proteases, and aids in protein purification; doesn't affect cellulase.

Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2], facilitates bacterial gene expression modulation in response to cell density escalation and triggers IL-8 production in 16HBE human bronchial epithelial cells [3].

Deuterium-labeled Sulfamethazine, an antimicrobial for treating animal diseases.

Tacrolimus-13C-d2 is the 13C and deuterated compound of Tacrolimus.

Etzadroxil, a volatile ester, treats drug-resistant urinary infections.

Tilbroquinol is an antiprotozoal agent effective against amoebiasis.

Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic properties.

Acyclovir sodium is an antimetabolite. Acyclovir sodium inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis.

BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.

Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)

Ceftolozane (FR-264,205 or CXA-101) is a cephalosporin antibiotic for drug-resistant gram-negative and gram-positive infections, used with tazobactam.

Bromperidol hydrochloride is a D2 dopamine receptor antipsychotic; enhances Spectinomycin's mycobactericidal effects.

Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.

Desmeninol, found in urine and cytoplasm, is used in organic synthesis, dye-making, medicine, photo-coloring, and as a fungicide.

Cefepime dihydrochloride: fourth-gen cephalosporin, inhibits bacterial PBPs.

Gloxazone is an effective anaplasmacide with toxicity.

Methylisothiazolinone is a powerful synthetic biocide and preservative.

Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.

Florfenicol-d3 is a deuterated compound of Florfenicol.

Zinc pyrithione (Standard) is an analytical standard and reference sample. Zinc pyrithione (OM-1563) disrupts membrane transport by inhibiting proton pumps.

Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.

Alafosfalin is a Chemotherapeutic agent.

3-Nitrophenylboronic acid has antibacterial activity and can be used in research and experiments in the field of life sciences.

Sulbactam pivoxil is a prodrug of sulbactam, exhibiting oral bioavailability and superior absorption. Sulbactam functions as a β-lactamase inhibitor.

Hygromycin B (Standard) is the standard substance of Hygromycin B, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis in both prokaryotic and eukaryotic cells by interfering with translocation and causing mistranslation by the 70S ribosome. It is commonly used for the selection of cells transfected with the hph or hyg resistance gene.

Cefoxitin, an oral 2nd-gen cephalosporin antibiotic, combats Gram+/- & anaerobes, for abdominal and gynecological infections.

Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

Sulfadimethoxypyrimidine D4 is a deuterated sulfonamide antibiotic with broad-spectrum effects.

Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.

Vitamin D3-d3 is a deuterated compound of Vitamin D3.

Phenazine is a dibenzo annulated pyrazine and the parent substance of many dyestuffs.

Acyclovir-d4 is a deuterated compound of Acyclovir. Acyclovir has a CAS number of 59277-89-3. Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.

Chloramphenicol-d5 is a deuterated compound of Chloramphenicol. Chloramphenicol has a CAS number of 56-75-7. Chloramphenicol, a broad-spectrum antibiotic, blocks bacterial protein synthesis.

Letrazuril is an antibacterial compound with inhibitory activity against Eimeria, Mycobacterium bovis BCG, and Mycobacterium tuberculosis.

Sulfadimethoxine D4 is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections.

Chlorhexidine diacetate (Standard) is the standard substance of Chlorhexidine diacetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.

Captan (Standard) is the standard substance of Captan, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Captan (Aacaptan) is a phthalimide fungicide that disrupts oocyte development.Captan is cytotoxic to mammalian cells and enhances the cytotoxicity of hydrogen peroxide.Captan reduces the incidence of BFR and AFR in orchards.

(S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid is a biochemical reagent that can be used in biological research.

Terizidone is a derivate of cycloserine with bacteriostatic activity.

Balofloxacin is a fluoroquinolone antibiotic with oral activity.

Sulfapyridine (Standard) is the standard substance of Sulfapyridine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.

G-418, or Geneticin, is an aminoglycoside antibiotic similar to gentamicin; it's toxic to all cells and blocks protein synthesis.

Gentamicin C1a, a major component with antibacterial activity, is the precursor to Etimicin.

Primulasaponin 1 is a useful organic compound for research related to life sciences. The catalog number is T124469 and the CAS number is 65312-86-9.

Cephalexin monohydrate (Cephalexin hydrate) is a cephalosporin antibiotic with significant antibacterial activity that inhibits bacterial proliferation.

Benzothiohydrazide is an analog of isoniazid with anti-tuberculosis activity and can be used to isolate fungi and bacteria.

Sulfamonomethoxine D4: deuterium-labeled, long-acting antibacterial sulfonamide; blocks folic acid synthesis in blood kinetics.

Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.

Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.