Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3359 produits trouvés pour "Antibactérien"
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Topoisomerase inhibitor 5
CAS :Topoisomerase inhibitor 5 (compound 158) is an inhibitor of bacterial topoisomerase, with a minimum inhibitory concentration of 0.125 μg/mL, and exhibits anti-tuberculosis activity.Formule :C24H25FN4O6Couleur et forme :SolidMasse moléculaire :484.477BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.61GSK-3036656 free base
CAS :GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.Formule :C10H13BClNO4Couleur et forme :SolidMasse moléculaire :257.48PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formule :C16H27N5O3SCouleur et forme :SolidMasse moléculaire :369.48NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formule :C22H24FN5O5SCouleur et forme :SolidMasse moléculaire :489.52Carbonic anhydrase inhibitor 28
Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.Formule :C24H24FN5O7SCouleur et forme :SolidMasse moléculaire :545.54RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Formule :C12H10F2OCouleur et forme :SolidMasse moléculaire :208.2Enzyme-IN-3 disodium
CAS :Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Formule :C20H13N3Na2O8S2Couleur et forme :SolidMasse moléculaire :533.442Metallo-β-lactamase-IN-16
CAS :Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Formule :C16H16N8O4S3Couleur et forme :SolidMasse moléculaire :480.54MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3ZG297
CAS :ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63NDM-1 inhibitor-5
CAS :NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Formule :C24H23NO4Couleur et forme :SolidMasse moléculaire :389.44Antibacterial agent 204
CAS :Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].Formule :C14H18N2Couleur et forme :SolidMasse moléculaire :214.31PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Formule :C18H20ClN3OSCouleur et forme :SolidMasse moléculaire :361.89Cetefloxacin
CAS :Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.Formule :C20H16F3N3O3Masse moléculaire :403.35Rf470 TFA
CAS :Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Formule :C28H31F3N4O7SCouleur et forme :SolidMasse moléculaire :624.63MetRS-IN-1
CAS :MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formule :C15H13N3O4SCouleur et forme :SolidMasse moléculaire :331.35Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Formule :C14H11N5O4S2Couleur et forme :SolidMasse moléculaire :377.47-Hydroxytropolone
CAS :7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12Gepotidacin mesylate dihydrate
CAS :Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formule :C25H36N6O8SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :580.65LeuRS-IN-1 hydrochloride
CAS :LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Formule :C10H14BCl2NO3Degré de pureté :97.34% - 99.61%Couleur et forme :SolidMasse moléculaire :277.94Tigemonam
CAS :Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formule :C12H15N5O9S2Degré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41Eravacycline dihydrochloride
CAS :Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formule :C27H33Cl2FN4O8Degré de pureté :95% - 99.68%Couleur et forme :SolidMasse moléculaire :631.48Durlobactam sodium salt
CAS :Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formule :C8H10N3NaO6SDegré de pureté :97.01% - 99.03%Couleur et forme :SolidMasse moléculaire :299.23Reutericyclin
CAS :Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formule :C20H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.46Bicyclomycin benzoate
CAS :Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formule :C19H22N2O8Couleur et forme :SolidMasse moléculaire :406.39α-Terpineol
CAS :Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.25Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS :Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formule :C12H13NO5SCouleur et forme :SolidMasse moléculaire :283.3Ramifenazone
CAS :Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formule :C14H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.321-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS :1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Formule :C14H11F2NO4Couleur et forme :SolidMasse moléculaire :295.2382N-Butylthiophosphoric triamide
CAS :N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Formule :C4H14N3PSCouleur et forme :SolidMasse moléculaire :167.21Dusquetide
CAS :Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formule :C25H47N9O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.709Pseudomonic acid C
CAS :Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formule :C26H44O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.62Lenampicillin hydrochloride
CAS :Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFormule :C21H24ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.951-Naphthalenemethanol
CAS :1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formule :C11H10OCouleur et forme :SolidMasse moléculaire :158.2Hexahydrohippuric acid
CAS :Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formule :C9H15NO3Couleur et forme :SolidMasse moléculaire :185.223trans-Clopenthixol dihydrochloride
CAS :Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Formule :C22H27Cl3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.89Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.42-Mercaptopyridine N-oxide sodium
CAS :2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Formule :C5H4NNaOSCouleur et forme :SolidMasse moléculaire :149.14Ciprofloxacin lactate
CAS :Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Formule :C20H24FN3O6Couleur et forme :SolidMasse moléculaire :421.43Sulfamonomethoxine sodium
CAS :Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Formule :C11H11N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.29Ulifloxacin
CAS :Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formule :C16H16FN3O3SCouleur et forme :SolidMasse moléculaire :349.38Cefadroxil (hydrate)
CAS :Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Formule :C16H19N3O6SCouleur et forme :White Crystalline SolidMasse moléculaire :381.404Cefetamet pivoxyl
CAS :Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Formule :C20H25N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.57Oleandomycin
CAS :Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formule :C35H61NO12Degré de pureté :98%Couleur et forme :White Amorphous Powder SolidMasse moléculaire :687.86l-Atabrine dihydrochloride
CAS :l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42N-(3-(Dimethylamino)propyl)tetradecanamide
CAS :N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Formule :C19H40N2OCouleur et forme :SolidMasse moléculaire :312.542Pulcherriminic acid
CAS :Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Formule :C12H20N2O4Couleur et forme :SolidMasse moléculaire :256.30MuRF1-IN-2
CAS :MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formule :C23H22N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.43Bacampicillin hydrochloride
CAS :Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formule :C21H28ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.98FtsZ-IN-10
CAS :Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Formule :C15H13ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.79CRS3123 dihydrochloride
CAS :CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formule :C19H21Br2Cl2N3O2SCouleur et forme :SolidMasse moléculaire :586.16PqsR/LasR-IN-1
CAS :PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formule :C24H20ClNO3Couleur et forme :SolidMasse moléculaire :405.87Zabofloxacin hydrochloride
CAS :Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Formule :C19H21ClFN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.86Phosalacine
CAS :Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Formule :C14H28N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.367TP0586532
CAS :TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Formule :C26H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52Methanesulfonyl Chloride-d3,13C
CAS :Formule :C2H3ClO2SCouleur et forme :Colourless OilMasse moléculaire :118.56Ribocil-C
CAS :Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5d-Atabrine dihydrochloride
CAS :d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42
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