Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3376 produits trouvés pour "Antibactérien"
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MetRS-IN-1
CAS :MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formule :C15H13N3O4SCouleur et forme :SolidMasse moléculaire :331.35Fabimycin
CAS :Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formule :C23H25ClN4O3Couleur et forme :SolidMasse moléculaire :440.92Antibacterial agent 236
CAS :Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.Formule :C26H27N5O2SCouleur et forme :SolidMasse moléculaire :473.59Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formule :C16H15N3O4Couleur et forme :SolidMasse moléculaire :313.31BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.618-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41MsbA-IN-2
MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formule :C22H24FN5O5SCouleur et forme :SolidMasse moléculaire :489.52(-)-15-Deoxyspergualin
CAS :(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formule :C17H37N7O3Couleur et forme :SolidMasse moléculaire :387.52Ro 24-4383
CAS :Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Formule :C32H31FN8O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :770.76MtTMPK-IN-2
CAS :MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formule :C23H24ClN3O3Couleur et forme :SolidMasse moléculaire :425.91MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3Keto lovastatin
CAS :Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.523Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37ZG297
CAS :ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63NFC nitro probe 1
CAS :NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.Formule :C19H19NO6Couleur et forme :SolidMasse moléculaire :357.3572'-Amino-2'-deoxyadenosine
CAS :2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.Formule :C10H14N6O3Couleur et forme :SolidMasse moléculaire :266.26L-threo-β-Hydroxyaspartic acid
CAS :L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic with activity against Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei, and Botrytis cinerea.Formule :C4H7NO5Couleur et forme :SolidMasse moléculaire :149.102Probenecid sodium
CAS :Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.Formule :C13H18NNaO4SCouleur et forme :SolidMasse moléculaire :307.341Piperacillin hydrate
CAS :Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Formule :C23H29N5O8SCouleur et forme :SolidMasse moléculaire :535.57Kikumycin A
CAS :Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.Formule :C13H17N7O2Couleur et forme :SolidMasse moléculaire :303.32Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formule :C18H18N4O5Couleur et forme :SolidMasse moléculaire :370.36MT0703
CAS :MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.Formule :C26H25N7O9S3Couleur et forme :SolidMasse moléculaire :675.71Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Formule :C14H11N5O4S2Couleur et forme :SolidMasse moléculaire :377.4N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS :N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.Formule :C17H19N5O5Couleur et forme :SolidMasse moléculaire :373.363DNA Gyrase-IN-16
CAS :DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.
Formule :C17H15N3O3Couleur et forme :SolidMasse moléculaire :309.3197-Hydroxytropolone
CAS :7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12Xeruborbactam isoboxil
CAS :Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.Formule :C15H16BFO6Couleur et forme :SolidMasse moléculaire :322.093Anti-MRSA agent 3
CAS :Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386L 689065
CAS :L 689065 is a 5-lipoxygenase inhibitor.Formule :C35H33ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.17RNAP-σ interaction inhibitor-2
CAS :RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formule :C27H19Cl3N2O6S2Couleur et forme :SolidMasse moléculaire :637.939Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26Penethamate hydriodide
CAS :Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.Formule :C22H32IN3O4SCouleur et forme :SolidMasse moléculaire :561.477Cetefloxacin
CAS :Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.Formule :C20H16F3N3O3Masse moléculaire :403.35Dioxidine
CAS :Dioxidine is an antimicrobial agent that can inhibit bacterial growth. It is utilized in research on pyogenic infections.Formule :C10H10N2O4Couleur et forme :SolidMasse moléculaire :222.197FG-2101
CAS :FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Formule :C30H32N5O6PCouleur et forme :SolidMasse moléculaire :589.579Eravacycline dihydrochloride
CAS :Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formule :C27H33Cl2FN4O8Degré de pureté :95% - 99.68%Couleur et forme :SolidMasse moléculaire :631.48LeuRS-IN-1 hydrochloride
CAS :LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Formule :C10H14BCl2NO3Degré de pureté :97.34% - 99.61%Couleur et forme :SolidMasse moléculaire :277.94Gepotidacin mesylate dihydrate
CAS :Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formule :C25H36N6O8SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :580.65Tigemonam
CAS :Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formule :C12H15N5O9S2Degré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41Durlobactam sodium salt
CAS :Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formule :C8H10N3NaO6SDegré de pureté :97.01% - 99.03%Couleur et forme :SolidMasse moléculaire :299.23Reutericyclin
CAS :Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formule :C20H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.46Bicyclomycin benzoate
CAS :Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formule :C19H22N2O8Couleur et forme :SolidMasse moléculaire :406.39α-Terpineol
CAS :Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.25Ulifloxacin
CAS :Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formule :C16H16FN3O3SCouleur et forme :SolidMasse moléculaire :349.38Phosalacine
CAS :Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Formule :C14H28N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.367Cefadroxil (hydrate)
CAS :Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Formule :C16H19N3O6SCouleur et forme :White Crystalline SolidMasse moléculaire :381.404CRS3123 dihydrochloride
CAS :CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formule :C19H21Br2Cl2N3O2SCouleur et forme :SolidMasse moléculaire :586.161-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS :1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Formule :C14H11F2NO4Couleur et forme :SolidMasse moléculaire :295.2382Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.4MuRF1-IN-2
CAS :MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formule :C23H22N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.43FtsZ-IN-10
CAS :Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Formule :C15H13ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.79Sulfamonomethoxine sodium
CAS :Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Formule :C11H11N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.29N-Butylthiophosphoric triamide
CAS :N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Formule :C4H14N3PSCouleur et forme :SolidMasse moléculaire :167.21Lenampicillin hydrochloride
CAS :Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFormule :C21H24ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.95Cefetamet pivoxyl
CAS :Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Formule :C20H25N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.57trans-Clopenthixol dihydrochloride
CAS :Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Formule :C22H27Cl3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.89Oleandomycin
CAS :Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formule :C35H61NO12Degré de pureté :98%Couleur et forme :White Amorphous Powder SolidMasse moléculaire :687.86Bacampicillin hydrochloride
CAS :Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formule :C21H28ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.98l-Atabrine dihydrochloride
CAS :l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42Dusquetide
CAS :Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formule :C25H47N9O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.709N-(3-(Dimethylamino)propyl)tetradecanamide
CAS :N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Formule :C19H40N2OCouleur et forme :SolidMasse moléculaire :312.542Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS :Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formule :C12H13NO5SCouleur et forme :SolidMasse moléculaire :283.3Zabofloxacin hydrochloride
CAS :Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Formule :C19H21ClFN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.86Pulcherriminic acid
CAS :Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Formule :C12H20N2O4Couleur et forme :SolidMasse moléculaire :256.30PqsR/LasR-IN-1
CAS :PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formule :C24H20ClNO3Couleur et forme :SolidMasse moléculaire :405.872-Mercaptopyridine N-oxide sodium
CAS :2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Formule :C5H4NNaOSCouleur et forme :SolidMasse moléculaire :149.14Ciprofloxacin lactate
CAS :Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Formule :C20H24FN3O6Couleur et forme :SolidMasse moléculaire :421.431-Naphthalenemethanol
CAS :1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formule :C11H10OCouleur et forme :SolidMasse moléculaire :158.2Hexahydrohippuric acid
CAS :Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formule :C9H15NO3Couleur et forme :SolidMasse moléculaire :185.223Ramifenazone
CAS :Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formule :C14H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.32Pseudomonic acid C
CAS :Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formule :C26H44O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.62TP0586532
CAS :TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Formule :C26H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52Methanesulfonyl Chloride-d3,13C
CAS :Formule :C2H3ClO2SCouleur et forme :Colourless OilMasse moléculaire :118.56Ribocil-C
CAS :Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5d-Atabrine dihydrochloride
CAS :d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42
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