Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3308 produits trouvés pour "Antibactérien"
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Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39Pyrromycin
CAS :Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formule :C30H35NO11Couleur et forme :SolidMasse moléculaire :585.60Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Formule :C18H27N3O2S3Couleur et forme :SolidMasse moléculaire :413.62NDM-1 inhibitor-7
CAS :NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.Formule :C9H10N2OS2Couleur et forme :SolidMasse moléculaire :226.319D-CS319
CAS :D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formule :C7H11NO2S3Couleur et forme :SolidMasse moléculaire :237.36OSUAB-0284
CAS :OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.Formule :C22H23FN6O6Couleur et forme :SolidMasse moléculaire :486.45Antibacterial agent 278
CAS :Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.Formule :C24H17ClF2N4O3Couleur et forme :SolidMasse moléculaire :482.878-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41DNA ligase-IN-2
CAS :DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.Formule :C13H8FN3O3Couleur et forme :SolidMasse moléculaire :273.219NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formule :C22H24FN5O5SCouleur et forme :SolidMasse moléculaire :489.52MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3MsbA-IN-2
MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31Piperacillin hydrate
CAS :Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Formule :C23H29N5O8SCouleur et forme :SolidMasse moléculaire :535.57MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Formule :C16H23N3O9Couleur et forme :SolidMasse moléculaire :401.37DHFS-IN-1
CAS :DHFS-IN-1 (Compound 3) is an inhibitor of dihydrofolate synthetase (DHFS) with an IC50 of 2.6 μM. It is applicable for research into infectious diseases related to bacterial folate synthesis.Formule :C16H16N8O2Couleur et forme :SolidMasse moléculaire :352.35ZG297
CAS :<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37PROTAC eDHFR Degrader-2
CAS :PROTACeDHFR Degrader-2 (compound 7b) is an effective degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), capable of reliably degrading eDHFR-tagged proteins.Formule :C34H40N8O9Masse moléculaire :704.73Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formule :C24H28FN5O8Couleur et forme :SolidMasse moléculaire :533.51FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Formule :C21H16ClF2NO2Couleur et forme :SolidMasse moléculaire :387.81
