Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3153 produits trouvés pour "Antibactérien"
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Gougerotin
CAS :Gougerotin is an inhibitor of protein synthesis.Formule :C16H25N7O8Couleur et forme :SolidMasse moléculaire :443.41Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Formule :C19H24N2O4Couleur et forme :SolidMasse moléculaire :344.4NusB-IN-1
NusB-IN-1 (22r) is an oral bacterial rRNA inhibitor, effective against MRSA and VRSA.Formule :C21H16N2O3Couleur et forme :SolidMasse moléculaire :344.36Antibacterial agent 90
Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.Formule :C30H42N2O6Couleur et forme :SolidMasse moléculaire :526.66LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Formule :C21H16ClN3O2Couleur et forme :SolidMasse moléculaire :377.829-tert-Butyldoxycycline
CAS :<p>9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.</p>Formule :C26H32N2O8Couleur et forme :SolidMasse moléculaire :500.541Pneumolysin-IN-1
CAS :Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].Formule :C23H16Cl2N2O4Couleur et forme :SolidMasse moléculaire :455.29MtTMPK-IN-5
<p>MtTMPK-IN-5 inhibits Mtb TMPK with IC50 of 34 μM and fights tuberculosis with MIC of 12.5 μM, aiding TB research.</p>Formule :C21H23N5O2Couleur et forme :SolidMasse moléculaire :377.44Lavendomycin
CAS :Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.Formule :C29H50N10O8Couleur et forme :SolidMasse moléculaire :666.77Pyrromycin
CAS :Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formule :C30H35NO11Couleur et forme :SolidMasse moléculaire :585.60Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formule :C23H27N3O2SCouleur et forme :SolidMasse moléculaire :409.54Squalamine lactate
CAS :Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Formule :C37H71N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.04AK-968-11563024
CAS :<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formule :C18H13I2N9O5Couleur et forme :SolidMasse moléculaire :689.162MK-3402
CAS :<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formule :C15H19N9O5S2Couleur et forme :SolidMasse moléculaire :469.50FtsZ-IN-13
CAS :<p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>Formule :C18H14N2O4S2Couleur et forme :SolidMasse moléculaire :386.445Fenbenicillin potassium
CAS :<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Formule :C22H22KN2O5SCouleur et forme :SolidMasse moléculaire :465.584Antibacterial agent 113
Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.Formule :C29H18ClN5OCouleur et forme :SolidMasse moléculaire :487.94Antibacterial agent 259
CAS :Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.Formule :C7H6ClN3O2SCouleur et forme :SolidMasse moléculaire :231.659Cilastatin ammonium salt
CAS :Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formule :C16H29N3O5SCouleur et forme :SolidMasse moléculaire :375.48Xeruborbactam
CAS :QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Formule :C10H8BFO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.98Palmitanilide
CAS :Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formule :C22H37NOCouleur et forme :SolidMasse moléculaire :331.535LasR antagonist 1
CAS :LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Formule :C20H15F3N2O3Couleur et forme :SolidMasse moléculaire :388.34K13787
CAS :<p>K13787 is an acetohydroxy acid synthase (AHAS) inhibitor with antibacterial properties. It exhibits antimicrobial activity against various non-tuberculous mycobacteria (NTM) as well as clarithromycin (CLR) resistant strains.</p>Formule :C14H11F2N5O4SCouleur et forme :SolidMasse moléculaire :383.33JPL
CAS :JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formule :C19H20Cl2O2Couleur et forme :SolidMasse moléculaire :351.27ROS inducer 9
CAS :<p>ROS inducer 9 (compound 4e) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 0.25 μg/mL against Escherichia coli. It eradicates bacteria by inhibiting GSH activity and increasing ROS levels. Additionally, ROS inducer 9 exhibits low toxicity toward red blood cells and RAW 264.7 cells.</p>Formule :C26H26BrF4N3O3Couleur et forme :SolidMasse moléculaire :584.401Fostriecin (free base)
CAS :Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Formule :C19H27O9PCouleur et forme :SolidMasse moléculaire :430.39BAR-072
CAS :<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Formule :C18H13N3O6Couleur et forme :SolidMasse moléculaire :367.312MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formule :C22H24N4O3Couleur et forme :SolidMasse moléculaire :392.45BAS-118
CAS :<p>BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.</p>Formule :C20H18N2O2Couleur et forme :SolidMasse moléculaire :318.369Metallo-β-lactamase-IN-13
CAS :<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Formule :C15H10F3N7O2S2Couleur et forme :SolidMasse moléculaire :441.41MA220607
CAS :<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Formule :C34H38INCouleur et forme :SolidMasse moléculaire :587.58Cefempidone
CAS :Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.Formule :C22H21N7O6S2Masse moléculaire :543.58Antibacterial agent 68
Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.Formule :C26H25BrN4O7Couleur et forme :SolidMasse moléculaire :585.4trans-Clopenthixol
CAS :<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formule :C22H25ClN2OSCouleur et forme :SolidMasse moléculaire :400.965Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formule :C17H23F3N8O10SCouleur et forme :SolidMasse moléculaire :588.47BRD-4592
CAS :BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.Formule :C17H15FN2OCouleur et forme :SolidMasse moléculaire :282.312Pks13-TE inhibitor 4
CAS :<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formule :C26H25N5O6Masse moléculaire :503.51RCB18350
CAS :<p>RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.</p>Formule :C19H18F3N3O4SCouleur et forme :SolidMasse moléculaire :441.424PKZ18
CAS :PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.Formule :C22H26N2O3SCouleur et forme :SolidMasse moléculaire :398.518Antibacterial agent 266
CAS :Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.246HT1171
CAS :<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Formule :C7H4N2O4S2Couleur et forme :SolidMasse moléculaire :244.248DNA Gyrase-IN-13
CAS :<p>DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.</p>Formule :C15H21N3O3SCouleur et forme :SolidMasse moléculaire :323.41Kikumycin A
CAS :<p>Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.</p>Formule :C13H17N7O2Couleur et forme :SolidMasse moléculaire :303.32Antibacterial agent 261
CAS :Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).Formule :C18H24N4O3S2Couleur et forme :SolidMasse moléculaire :408.538MT0703
CAS :MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.Formule :C26H25N7O9S3Couleur et forme :SolidMasse moléculaire :675.71epi-D-Captopril
CAS :<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Formule :C9H15NO3SCouleur et forme :SolidMasse moléculaire :217.285Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formule :C16H15N3O4Couleur et forme :SolidMasse moléculaire :313.31Antibacterial agent 174
CAS :<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Formule :C25H30FN2NaO5Couleur et forme :SolidMasse moléculaire :480.5Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formule :C16H23N3S2Couleur et forme :SolidMasse moléculaire :321.5KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Formule :C12H10BN3O2SCouleur et forme :SolidMasse moléculaire :271.17-APRA
CAS :7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formule :C10H12N2O3SMasse moléculaire :240.28Benzisothiazolone
CAS :Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Formule :C7H5NOSCouleur et forme :SolidMasse moléculaire :151.19Aurantiogliocladin
CAS :<p>Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.</p>Formule :C10H12O4Couleur et forme :SolidMasse moléculaire :196.2MtTMPK-IN-2
CAS :MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formule :C23H24ClN3O3Couleur et forme :SolidMasse moléculaire :425.91QPX7728 bis-acetoxy methyl ester
CAS :QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.08Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46LolCDE-IN-2
CAS :<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40Metallo-β-lactamase-IN-16
CAS :Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Formule :C16H16N8O4S3Couleur et forme :SolidMasse moléculaire :480.54Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formule :C17H10ClFN2Couleur et forme :SolidMasse moléculaire :296.73Lapyrium chloride
CAS :Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formule :C21H35ClN2O3Masse moléculaire :398.97Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24OPC-167832
CAS :OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formule :C21H20ClF3N2O4Couleur et forme :SolidMasse moléculaire :456.84Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44Antibacterial agent 236
CAS :<p>Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.</p>Formule :C26H27N5O2SCouleur et forme :SolidMasse moléculaire :473.59Mazethramycin
CAS :<p>Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.</p>Formule :C17H19N3O4Masse moléculaire :329.35Atramycin A
CAS :<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formule :C25H24O9Couleur et forme :SolidMasse moléculaire :468.453Anti-MRSA agent 27
CAS :<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formule :C15H10F3N3OSCouleur et forme :SolidMasse moléculaire :337.32Kalafungin
CAS :Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Formule :C16H12O6Couleur et forme :SolidMasse moléculaire :300.26β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Formule :C21H17Cl3O7Couleur et forme :SolidMasse moléculaire :487.71MtTMPK-IN-8
<p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>Formule :C24H24N6O7Couleur et forme :SolidMasse moléculaire :508.48Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Formule :C25H18N2O2SCouleur et forme :SolidMasse moléculaire :410.49Pisiferic acid
CAS :<p>Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoid</p>Formule :C20H28O3Couleur et forme :SolidMasse moléculaire :316.43Gepotidacin hydrochloride
CAS :Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Formule :C24H29ClN6O3Couleur et forme :SolidMasse moléculaire :484.98Eravacycline
CAS :Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formule :C27H31FN4O8Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :558.56ACHN-975
CAS :ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formule :C20H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.41MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Formule :C27H29ClN6O3Couleur et forme :SolidMasse moléculaire :521.01844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48AVE-1330A sodium
CAS :AVE-1330A sodium is a beta-Lactamase inhibitor.Formule :C7H10N3NaO6SCouleur et forme :SolidMasse moléculaire :287.23MB076
CAS :MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formule :C9H12BN7O5S2Masse moléculaire :373.18Doxazosin impurity 12
CAS :<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formule :C10H6O5SCouleur et forme :SolidMasse moléculaire :238.217Keto lovastatin
CAS :Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.523RNAP-σ interaction inhibitor-2
CAS :RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formule :C27H19Cl3N2O6S2Couleur et forme :SolidMasse moléculaire :637.939Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.86Ro 24-4383
CAS :Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Formule :C32H31FN8O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :770.76Cefoxazole
CAS :<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formule :C21H18ClN3O7SCouleur et forme :SolidMasse moléculaire :491.902Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28MBL-IN-5
CAS :MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formule :C20H16ClNO3Couleur et forme :SolidMasse moléculaire :353.80Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Formule :C14H21N3S2Couleur et forme :SolidMasse moléculaire :295.47SPR719
CAS :SPR719 is an inhibitor of gyrase B, has bactericidal activity.Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46(4-Aminobenzoyl)-D-glutamic acid
CAS :<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formule :C12H14N2O5Couleur et forme :SolidMasse moléculaire :266.25Antibacterial agent 279
CAS :Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.Formule :C9H11NO2SCouleur et forme :SolidMasse moléculaire :197.25H052
CAS :<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Formule :C21H15ClFN3O4SCouleur et forme :SolidMasse moléculaire :459.882'-Amino-2'-deoxyadenosine
CAS :<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Formule :C10H14N6O3Masse moléculaire :266.264-Bromo A23187
CAS :4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Formule :C29H36BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.52Anti-MRSA agent 3
CAS :Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Antibacterial agent 281
CAS :Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formule :C23H24N6OCouleur et forme :SolidMasse moléculaire :400.48Aquayamycin
CAS :Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Formule :C25H26O10Couleur et forme :SolidMasse moléculaire :486.47Antibacterial agent 99
CAS :Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42Asukamycin
CAS :<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formule :C31H34N2O7Couleur et forme :SolidMasse moléculaire :546.61Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formule :C18H18N4O5Couleur et forme :SolidMasse moléculaire :370.36Aurachin C
CAS :<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.535NBTI 5463
CAS :NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Formule :C25H30N6O4Couleur et forme :SolidMasse moléculaire :478.54TBAJ-5307
CAS :TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Formule :C30H35BrN4O6Couleur et forme :SolidMasse moléculaire :627.53(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at aFormule :C28H35F3N4O3Couleur et forme :SolidMasse moléculaire :532.6OSUAB-0284
CAS :OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.Formule :C22H23FN6O6Couleur et forme :SolidMasse moléculaire :486.45NBTIs-IN-5
CAS :NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48Diclosulam
CAS :Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Formule :C13H10Cl2FN5O3SCouleur et forme :SolidMasse moléculaire :406.22Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Formule :C14H11N5O4S2Couleur et forme :SolidMasse moléculaire :377.4BDM91288
CAS :BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].Formule :C17H22ClN5Couleur et forme :SolidMasse moléculaire :331.84Xeruborbactam isoboxil
CAS :<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formule :C15H16BFO6Couleur et forme :SolidMasse moléculaire :322.093Metallo-β-lactamase-IN-14
CAS :<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Formule :C20H22N8O2S2Couleur et forme :SolidMasse moléculaire :470.57Kendomycin
CAS :Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formule :C29H42O6Couleur et forme :SolidMasse moléculaire :486.64L 689065
CAS :L 689065 is a 5-lipoxygenase inhibitor.Formule :C35H33ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.17RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Formule :C25H26N6O7Couleur et forme :SolidMasse moléculaire :522.51LeuRS-IN-1 hydrochloride
CAS :<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Formule :C10H14BCl2NO3Degré de pureté :97.34% - 99.61%Couleur et forme :SolidMasse moléculaire :277.94Gepotidacin mesylate dihydrate
CAS :Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formule :C25H36N6O8SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :580.65Tigemonam
CAS :<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Formule :C12H15N5O9S2Degré de pureté :99.03% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41Eravacycline dihydrochloride
CAS :<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Formule :C27H33Cl2FN4O8Degré de pureté :94.59% - 95%Couleur et forme :SolidMasse moléculaire :631.48Durlobactam sodium salt
CAS :Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formule :C8H10N3NaO6SDegré de pureté :97.01% - 99.03%Couleur et forme :SolidMasse moléculaire :299.23Reutericyclin
CAS :Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formule :C20H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.46Bicyclomycin benzoate
CAS :Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formule :C19H22N2O8Couleur et forme :SolidMasse moléculaire :406.39α-Terpineol
CAS :<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.25trans-Clopenthixol dihydrochloride
CAS :<p>Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].</p>Formule :C22H27Cl3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.89Pulcherriminic acid
CAS :<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Formule :C12H20N2O4Couleur et forme :SolidMasse moléculaire :256.30l-Atabrine dihydrochloride
CAS :l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42Zabofloxacin hydrochloride
CAS :<p>Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.</p>Formule :C19H21ClFN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.861-Naphthalenemethanol
CAS :1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formule :C11H10OCouleur et forme :SolidMasse moléculaire :158.2Oleandomycin
CAS :Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formule :C35H61NO12Degré de pureté :98%Couleur et forme :White Amorphous Powder SolidMasse moléculaire :687.86Bacampicillin hydrochloride
CAS :Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formule :C21H28ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.982-Mercaptopyridine N-oxide sodium
CAS :<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Formule :C5H4NNaOSCouleur et forme :SolidMasse moléculaire :149.14Phosalacine
CAS :<p>Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.</p>Formule :C14H28N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.367PqsR/LasR-IN-1
CAS :PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formule :C24H20ClNO3Couleur et forme :SolidMasse moléculaire :405.87CRS3123 dihydrochloride
CAS :CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formule :C19H21Br2Cl2N3O2SCouleur et forme :SolidMasse moléculaire :586.16Dusquetide
CAS :Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formule :C25H47N9O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.709Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS :Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formule :C12H13NO5SCouleur et forme :SolidMasse moléculaire :283.3FtsZ-IN-10
CAS :<p>Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.</p>Formule :C15H13ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.79Ramifenazone
CAS :Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formule :C14H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.32Lenampicillin hydrochloride
CAS :<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Formule :C21H24ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.95Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.4Ulifloxacin
CAS :Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formule :C16H16FN3O3SCouleur et forme :SolidMasse moléculaire :349.38Sulfamonomethoxine sodium
CAS :<p>Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].</p>Formule :C11H11N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.29Pseudomonic acid C
CAS :Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formule :C26H44O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.62MuRF1-IN-2
CAS :MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formule :C23H22N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.43N-Butylthiophosphoric triamide
CAS :<p>N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.</p>Formule :C4H14N3PSCouleur et forme :SolidMasse moléculaire :167.21Cefadroxil (hydrate)
CAS :<p>Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.</p>Formule :C16H19N3O6SCouleur et forme :White Crystalline SolidMasse moléculaire :381.404Hexahydrohippuric acid
CAS :Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formule :C9H15NO3Couleur et forme :SolidMasse moléculaire :185.223Cefetamet pivoxyl
CAS :<p>Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].</p>Formule :C20H25N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.57Ciprofloxacin lactate
CAS :<p>Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.</p>Formule :C20H24FN3O6Couleur et forme :SolidMasse moléculaire :421.43TP0586532
CAS :<p>TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.</p>Formule :C26H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52Methanesulfonyl Chloride-d3,13C
CAS :Formule :C2H3ClO2SCouleur et forme :Colourless OilMasse moléculaire :118.56d-Atabrine dihydrochloride
CAS :d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42Ribocil-C
CAS :Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5
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