Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3334 produits trouvés pour "Antibactérien"
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Fenbenicillin potassium
CAS :Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.Formule :C22H22KN2O5SCouleur et forme :SolidMasse moléculaire :465.584Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28OPC-167832
CAS :OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formule :C21H20ClF3N2O4Couleur et forme :SolidMasse moléculaire :456.84Kendomycin
CAS :Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formule :C29H42O6Couleur et forme :SolidMasse moléculaire :486.64AK-968-11563024
CAS :AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.Formule :C18H13I2N9O5Couleur et forme :SolidMasse moléculaire :689.162DNA Gyrase-IN-1
DNA Gyrase-IN-1: potent, selective promoter inhibitor. IC50: 2.6 μM, inhibits Mtb, MIC: 0.49 μM. Useful for tuberculosis research.Formule :C24H24FN7O6Couleur et forme :SolidMasse moléculaire :525.49GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formule :C13H20F3N5O8SCouleur et forme :SolidMasse moléculaire :463.39Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formule :C18H18N4O5Couleur et forme :SolidMasse moléculaire :370.36Antifungal agent 27
Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.Formule :C18H23N5OSCouleur et forme :SolidMasse moléculaire :357.47Lavendomycin
CAS :Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.Formule :C29H50N10O8Couleur et forme :SolidMasse moléculaire :666.77Antibacterial agent 88
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.Formule :C31H44N2O6SCouleur et forme :SolidMasse moléculaire :572.76MtTMPK-IN-5
MtTMPK-IN-5 inhibits Mtb TMPK with IC50 of 34 μM and fights tuberculosis with MIC of 12.5 μM, aiding TB research.Formule :C21H23N5O2Couleur et forme :SolidMasse moléculaire :377.44MtTMPK-IN-8
MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.Formule :C24H24N6O7Couleur et forme :SolidMasse moléculaire :508.489-tert-Butyldoxycycline
CAS :9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.Formule :C26H32N2O8Couleur et forme :SolidMasse moléculaire :500.541LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Formule :C21H16ClN3O2Couleur et forme :SolidMasse moléculaire :377.82ACHN-975
CAS :ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formule :C20H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.41Rf470 TFA
CAS :Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Formule :C28H31F3N4O7SCouleur et forme :SolidMasse moléculaire :624.63Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Formule :C21H27N3SCouleur et forme :SolidMasse moléculaire :353.52Nitrovin
CAS :Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.Formule :C14H12N6O6Couleur et forme :SolidMasse moléculaire :360.28Streptothricin F
CAS :Streptothricin F is a biochemical.Formule :C19H34N8O8Couleur et forme :SolidMasse moléculaire :502.52MetRS-IN-1
CAS :MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formule :C15H13N3O4SCouleur et forme :SolidMasse moléculaire :331.35Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Formule :C16H35N3O2Couleur et forme :SolidMasse moléculaire :301.47Eravacycline
CAS :Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formule :C27H31FN4O8Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :558.56VEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.4(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS :(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.Formule :C26H36F3NO4SCouleur et forme :SolidMasse moléculaire :515.629BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formule :C25H30ClFN2OCouleur et forme :SolidMasse moléculaire :428.97Apalcillin
CAS :Apalcillin (PC-904) combined with Ro 48-1220 (a penicillin sulfone β-lactamase inhibitor) exhibits broad-spectrum activity against Gram-negative aerobic and anaerobic bacteria, excluding Klebsiella acid-producing strains. This combination shows strong efficacy against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae with an effective MIC of 11 μg/mL. Additionally, it inhibits Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter at low MICs (0.25 to 4 μg/mL). However, it has limited efficacy against oxacillin-resistant staphylococci and some Gram-positive bacteria. Apalcillin/Ro 48-1220's effectiveness against certain extended-spectrum β-lactamase-producing Escherichia coli is comparable to piperacillin/tazobactam, though it is less effective against SHV-type β-lactamases.Formule :C25H23N5O6SMasse moléculaire :521.55Ph-Ph+
Ph-Ph+ is a dimerized phenanthroline derivative with antitumor, antibacterial, and antifungal effects.Formule :C24H17N4Couleur et forme :SolidMasse moléculaire :361.42Mazethramycin
CAS :Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.
Formule :C17H19N3O4Masse moléculaire :329.35PROTAC eDHFR Degrader-2
CAS :PROTACeDHFR Degrader-2 (compound 7b) is an effective degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), capable of reliably degrading eDHFR-tagged proteins.Formule :C34H40N8O9Masse moléculaire :704.73Lapyrium chloride
CAS :Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formule :C21H35ClN2O3Masse moléculaire :398.97Antibiofilm agent-4
CAS :Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.Formule :C15H15NO3Masse moléculaire :257.287-APRA
CAS :7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formule :C10H12N2O3SMasse moléculaire :240.28MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formule :C22H24N4O3Couleur et forme :SolidMasse moléculaire :392.45NDM-1 inhibitor-3
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.Formule :C16H12O4Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :268.26Ref: TM-T60454
1mg46,00€5mg87,00€10mg145,00€25mg279,00€50mg464,00€100mg677,00€500mg1.406,00€1mL*10mM (DMSO)95,00€Doxazosin impurity 12
CAS :Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.
Formule :C10H6O5SCouleur et forme :SolidMasse moléculaire :238.217Lambertellin
CAS :Lambertellin, an effective antibiotic, acts as both a bactericide and fungicide. It exerts anti-inflammatory effects in LPS-stimulated RAW 264.7 macrophages by modulating the activation of MAPK and NF-κB signaling pathways.Formule :C14H8O5Couleur et forme :SolidMasse moléculaire :256.21Anti-MRSA agent 2
CAS :Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.Formule :C18H10Br2N2OCouleur et forme :SolidMasse moléculaire :430.09Xeruborbactam
CAS :QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Formule :C10H8BFO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.98(E)-Cefodizime
CAS :(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.Formule :C20H20N6O7S4Couleur et forme :SolidMasse moléculaire :584.669Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Formule :C20H12ClN3O5Couleur et forme :SolidMasse moléculaire :409.78PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formule :C17H18ClN3OSCouleur et forme :SolidMasse moléculaire :347.86BAS-118
CAS :BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.Formule :C20H18N2O2Couleur et forme :SolidMasse moléculaire :318.369Cefamandole lithium
CAS :Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44MA220607
CAS :MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].Formule :C34H38INCouleur et forme :SolidMasse moléculaire :587.58GSK-3036656 free base
CAS :GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.Formule :C10H13BClNO4Couleur et forme :SolidMasse moléculaire :257.48epi-D-Captopril
CAS :epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.Formule :C9H15NO3SCouleur et forme :SolidMasse moléculaire :217.285Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formule :C16H23N3S2Couleur et forme :SolidMasse moléculaire :321.5NBTI 5463
CAS :NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Formule :C25H30N6O4Couleur et forme :SolidMasse moléculaire :478.547-Hydroxytropolone
CAS :7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formule :C16H27N5O3SCouleur et forme :SolidMasse moléculaire :369.48Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.268-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Formule :C12H10F2OCouleur et forme :SolidMasse moléculaire :208.2Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formule :C17H10ClFN2Couleur et forme :SolidMasse moléculaire :296.73QPX7728 bis-acetoxy methyl ester
CAS :QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.08PF 03709270
CAS :PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Formule :C19H27NO7S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.61NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formule :C22H24FN5O5SCouleur et forme :SolidMasse moléculaire :489.52(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Formule :C28H35F3N4O3Couleur et forme :SolidMasse moléculaire :532.6MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3HKI12134085
CAS :HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].
Formule :C18H18F3N3O5SCouleur et forme :SolidMasse moléculaire :445.41Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Formule :C8H12N2S2Couleur et forme :SolidMasse moléculaire :200.32VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Formule :C20H18ClNO4Couleur et forme :SolidMasse moléculaire :371.81Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formule :C16H15N3O4Couleur et forme :SolidMasse moléculaire :313.31ZG297
CAS :ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.
Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63MtTMPK-IN-2
CAS :MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formule :C23H24ClN3O3Couleur et forme :SolidMasse moléculaire :425.91NFC nitro probe 1
CAS :NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.Formule :C19H19NO6Couleur et forme :SolidMasse moléculaire :357.357Probenecid sodium
CAS :Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.Formule :C13H18NNaO4SCouleur et forme :SolidMasse moléculaire :307.341Anticaries agent-1
CAS :Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.Formule :C15H12O4Couleur et forme :SolidMasse moléculaire :256.253N-Cbz-L-Cysteine
CAS :N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].Formule :C11H13NO4SCouleur et forme :SolidMasse moléculaire :255.29DC-159a
CAS :DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Formule :C21H23F2N3O40·5H2OCouleur et forme :SolidMasse moléculaire :428.42952-Bromo-2'-methoxyacetophenone
CAS :2-Bromo-2'-methoxyacetophenone acts as an irreversible inhibitor of MurA, effectively inhibiting MurA in E. coli with an IC50 of 0.38 μM. This compound helps inhibit bacterial cell wall synthesis, making it useful in antimicrobial research.Formule :C9H9BrO2Masse moléculaire :229.07D-CS319
CAS :D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formule :C7H11NO2S3Couleur et forme :SolidMasse moléculaire :237.36Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formule :C24H28FN5O8Couleur et forme :SolidMasse moléculaire :533.51FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Formule :C21H16ClF2NO2Couleur et forme :SolidMasse moléculaire :387.81BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.61MBL-IN-5
CAS :MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formule :C20H16ClNO3Couleur et forme :SolidMasse moléculaire :353.80H052
CAS :H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.
Formule :C21H15ClFN3O4SCouleur et forme :SolidMasse moléculaire :459.88Urease-IN-1
Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).Formule :C17H12BrFN4O2SCouleur et forme :SolidMasse moléculaire :435.27Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formule :C22H28N6OCouleur et forme :SolidMasse moléculaire :392.5RNAP-σ interaction inhibitor-1
CAS :RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.Formule :C19H11Cl3N2O6S2Couleur et forme :SolidMasse moléculaire :533.79AAA-10 formic
AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.Formule :C26H43FO7SCouleur et forme :SolidMasse moléculaire :518.68Bilanafos
CAS :Bilanafos is an agent of Anti-Bacterial.Formule :C11H22N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.28DL-2-Aminopimelic Acid
CAS :DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.Formule :C7H13NO4Couleur et forme :SolidMasse moléculaire :175.18MK-3402
CAS :MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .Formule :C15H19N9O5S2Couleur et forme :SolidMasse moléculaire :469.50WQ3810
CAS :WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.Formule :C22H22F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.44Palmitanilide
CAS :Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formule :C22H37NOCouleur et forme :SolidMasse moléculaire :331.535Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Formule :C18H27N3O2S3Couleur et forme :SolidMasse moléculaire :413.62FG-2101
CAS :FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Formule :C30H32N5O6PCouleur et forme :SolidMasse moléculaire :589.579Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Formule :C22H27N3OSCouleur et forme :SolidMasse moléculaire :381.53BAR-072
CAS :BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Formule :C18H13N3O6Couleur et forme :SolidMasse moléculaire :367.312PCTR1
CAS :PCTR1, derived from DHA, hastens inflammation resolution and boosts macrophage function, reducing PGE2, PGD2, and TXB2 in mice.Formule :C32H47N3O9SCouleur et forme :SolidMasse moléculaire :649.8Fabimycin
CAS :Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formule :C23H25ClN4O3Couleur et forme :SolidMasse moléculaire :440.92Eravacycline dihydrochloride
CAS :Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formule :C27H33Cl2FN4O8Degré de pureté :95% - 99.68%Couleur et forme :SolidMasse moléculaire :631.48Gepotidacin mesylate dihydrate
CAS :Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formule :C25H36N6O8SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :580.65LeuRS-IN-1 hydrochloride
CAS :LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Formule :C10H14BCl2NO3Degré de pureté :97.34% - 99.61%Couleur et forme :SolidMasse moléculaire :277.94Tigemonam
CAS :Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formule :C12H15N5O9S2Degré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41Durlobactam sodium salt
CAS :Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formule :C8H10N3NaO6SDegré de pureté :97.01% - 99.03%Couleur et forme :SolidMasse moléculaire :299.23Bicyclomycin benzoate
CAS :Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formule :C19H22N2O8Couleur et forme :SolidMasse moléculaire :406.39Reutericyclin
CAS :Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formule :C20H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.46α-Terpineol
CAS :Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.252-Mercaptopyridine N-oxide sodium
CAS :2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Formule :C5H4NNaOSCouleur et forme :SolidMasse moléculaire :149.14Zabofloxacin hydrochloride
CAS :Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Formule :C19H21ClFN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.86Sulfamonomethoxine sodium
CAS :Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Formule :C11H11N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.29Lenampicillin hydrochloride
CAS :Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFormule :C21H24ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.95Ramifenazone
CAS :Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formule :C14H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.32CRS3123 dihydrochloride
CAS :CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formule :C19H21Br2Cl2N3O2SCouleur et forme :SolidMasse moléculaire :586.16Pseudomonic acid C
CAS :Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formule :C26H44O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.62trans-Clopenthixol dihydrochloride
CAS :Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Formule :C22H27Cl3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.89l-Atabrine dihydrochloride
CAS :l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42Ulifloxacin
CAS :Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formule :C16H16FN3O3SCouleur et forme :SolidMasse moléculaire :349.38N-Butylthiophosphoric triamide
CAS :N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Formule :C4H14N3PSCouleur et forme :SolidMasse moléculaire :167.21Dusquetide
CAS :Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formule :C25H47N9O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.709N-(3-(Dimethylamino)propyl)tetradecanamide
CAS :N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Formule :C19H40N2OCouleur et forme :SolidMasse moléculaire :312.542Cefadroxil (hydrate)
CAS :Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Formule :C16H19N3O6SCouleur et forme :White Crystalline SolidMasse moléculaire :381.404MuRF1-IN-2
CAS :MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formule :C23H22N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.43Hexahydrohippuric acid
CAS :Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formule :C9H15NO3Couleur et forme :SolidMasse moléculaire :185.223PqsR/LasR-IN-1
CAS :PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formule :C24H20ClNO3Couleur et forme :SolidMasse moléculaire :405.87Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS :Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formule :C12H13NO5SCouleur et forme :SolidMasse moléculaire :283.3Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.4Ciprofloxacin lactate
CAS :Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Formule :C20H24FN3O6Couleur et forme :SolidMasse moléculaire :421.43Oleandomycin
CAS :Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formule :C35H61NO12Degré de pureté :98%Couleur et forme :White Amorphous Powder SolidMasse moléculaire :687.86Bacampicillin hydrochloride
CAS :Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formule :C21H28ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.98Cefetamet pivoxyl
CAS :Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Formule :C20H25N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.57FtsZ-IN-10
CAS :Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Formule :C15H13ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.79Pulcherriminic acid
CAS :Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Formule :C12H20N2O4Couleur et forme :SolidMasse moléculaire :256.301-Naphthalenemethanol
CAS :1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formule :C11H10OCouleur et forme :SolidMasse moléculaire :158.21-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS :1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Formule :C14H11F2NO4Couleur et forme :SolidMasse moléculaire :295.2382Phosalacine
CAS :Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Formule :C14H28N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.367TP0586532
CAS :TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Formule :C26H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52Methanesulfonyl Chloride-d3,13C
CAS :Formule :C2H3ClO2SCouleur et forme :Colourless OilMasse moléculaire :118.56d-Atabrine dihydrochloride
CAS :d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formule :C23H31Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.42Ribocil-C
CAS :Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5
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