Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3153 produits trouvés pour "Antibactérien"
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7-APRA
CAS :7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formule :C10H12N2O3SMasse moléculaire :240.28Benzisothiazolone
CAS :Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Formule :C7H5NOSCouleur et forme :SolidMasse moléculaire :151.19Aurantiogliocladin
CAS :<p>Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.</p>Formule :C10H12O4Couleur et forme :SolidMasse moléculaire :196.2MtTMPK-IN-2
CAS :MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formule :C23H24ClN3O3Couleur et forme :SolidMasse moléculaire :425.91QPX7728 bis-acetoxy methyl ester
CAS :QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.08Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46LolCDE-IN-2
CAS :<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40Metallo-β-lactamase-IN-16
CAS :Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Formule :C16H16N8O4S3Couleur et forme :SolidMasse moléculaire :480.54Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formule :C17H10ClFN2Couleur et forme :SolidMasse moléculaire :296.73Lapyrium chloride
CAS :Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formule :C21H35ClN2O3Masse moléculaire :398.97Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24OPC-167832
CAS :OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formule :C21H20ClF3N2O4Couleur et forme :SolidMasse moléculaire :456.84Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44Antibacterial agent 236
CAS :<p>Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.</p>Formule :C26H27N5O2SCouleur et forme :SolidMasse moléculaire :473.59Mazethramycin
CAS :<p>Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.</p>Formule :C17H19N3O4Masse moléculaire :329.35Atramycin A
CAS :<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formule :C25H24O9Couleur et forme :SolidMasse moléculaire :468.453Anti-MRSA agent 27
CAS :<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formule :C15H10F3N3OSCouleur et forme :SolidMasse moléculaire :337.32Kalafungin
CAS :Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Formule :C16H12O6Couleur et forme :SolidMasse moléculaire :300.26β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Formule :C21H17Cl3O7Couleur et forme :SolidMasse moléculaire :487.71MtTMPK-IN-8
<p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>Formule :C24H24N6O7Couleur et forme :SolidMasse moléculaire :508.48Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Formule :C25H18N2O2SCouleur et forme :SolidMasse moléculaire :410.49Pisiferic acid
CAS :<p>Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoid</p>Formule :C20H28O3Couleur et forme :SolidMasse moléculaire :316.43Gepotidacin hydrochloride
CAS :Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Formule :C24H29ClN6O3Couleur et forme :SolidMasse moléculaire :484.98Eravacycline
CAS :Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formule :C27H31FN4O8Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :558.56ACHN-975
CAS :ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formule :C20H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.41MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Formule :C27H29ClN6O3Couleur et forme :SolidMasse moléculaire :521.01844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48AVE-1330A sodium
CAS :AVE-1330A sodium is a beta-Lactamase inhibitor.Formule :C7H10N3NaO6SCouleur et forme :SolidMasse moléculaire :287.23MB076
CAS :MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formule :C9H12BN7O5S2Masse moléculaire :373.18Doxazosin impurity 12
CAS :<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formule :C10H6O5SCouleur et forme :SolidMasse moléculaire :238.217Keto lovastatin
CAS :Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.523RNAP-σ interaction inhibitor-2
CAS :RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formule :C27H19Cl3N2O6S2Couleur et forme :SolidMasse moléculaire :637.939Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.86Ro 24-4383
CAS :Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Formule :C32H31FN8O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :770.76Cefoxazole
CAS :<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formule :C21H18ClN3O7SCouleur et forme :SolidMasse moléculaire :491.902Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28MBL-IN-5
CAS :MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formule :C20H16ClNO3Couleur et forme :SolidMasse moléculaire :353.80Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Formule :C14H21N3S2Couleur et forme :SolidMasse moléculaire :295.47SPR719
CAS :SPR719 is an inhibitor of gyrase B, has bactericidal activity.Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46(4-Aminobenzoyl)-D-glutamic acid
CAS :<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formule :C12H14N2O5Couleur et forme :SolidMasse moléculaire :266.25Antibacterial agent 279
CAS :Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.Formule :C9H11NO2SCouleur et forme :SolidMasse moléculaire :197.25H052
CAS :<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Formule :C21H15ClFN3O4SCouleur et forme :SolidMasse moléculaire :459.882'-Amino-2'-deoxyadenosine
CAS :<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Formule :C10H14N6O3Masse moléculaire :266.264-Bromo A23187
CAS :4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Formule :C29H36BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.52Anti-MRSA agent 3
CAS :Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Antibacterial agent 281
CAS :Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formule :C23H24N6OCouleur et forme :SolidMasse moléculaire :400.48Aquayamycin
CAS :Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Formule :C25H26O10Couleur et forme :SolidMasse moléculaire :486.47Antibacterial agent 99
CAS :Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42Asukamycin
CAS :<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formule :C31H34N2O7Couleur et forme :SolidMasse moléculaire :546.61Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formule :C18H18N4O5Couleur et forme :SolidMasse moléculaire :370.36
