Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3240 produits trouvés pour "Antibactérien"
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TBAJ-5307
CAS :TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Formule :C30H35BrN4O6Couleur et forme :SolidMasse moléculaire :627.53FPI-1465
CAS :<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formule :C11H18N4O7SCouleur et forme :SolidMasse moléculaire :350.35BDM91288
CAS :BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].Formule :C17H22ClN5Couleur et forme :SolidMasse moléculaire :331.84Altersolanol A
CAS :Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.Formule :C16H16O8Couleur et forme :SolidMasse moléculaire :336.29N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS :N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.Formule :C17H19N5O5Couleur et forme :SolidMasse moléculaire :373.363NDM-1 inhibitor-5
CAS :NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Formule :C24H23NO4Couleur et forme :SolidMasse moléculaire :389.44Quorum sensing-IN-9
CAS :<p>Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.</p>Formule :C9H10OS2Couleur et forme :SolidMasse moléculaire :198.305Keto lovastatin
CAS :Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.523(4-Aminobenzoyl)-D-glutamic acid
CAS :<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formule :C12H14N2O5Couleur et forme :SolidMasse moléculaire :266.25JPL
CAS :JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formule :C19H20Cl2O2Couleur et forme :SolidMasse moléculaire :351.27InhA-IN-7
CAS :<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Formule :C17H18Cl2O2Couleur et forme :SolidMasse moléculaire :325.23MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).Formule :C23H18Cl2FN5OCouleur et forme :SolidMasse moléculaire :470.33MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Formule :C25H26N6O7Couleur et forme :SolidMasse moléculaire :522.51Antibacterial agent 81
CAS :Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Formule :C33H28N2O8Couleur et forme :SolidMasse moléculaire :580.58Deprodone
CAS :Deprodone is an active compound that inhibits key processes such as bacterial cell wall synthesis by interacting with hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). It is applied in the research of MRSA infections, inflammatory skin diseases, intestinal disorders, and fatty acid metabolism disorders.Formule :C21H28O4Couleur et forme :SolidMasse moléculaire :344.44MsbA-IN-5
MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.Formule :C23H19Cl2N5OCouleur et forme :SolidMasse moléculaire :452.34Antibiofilm agent-14
CAS :<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Formule :C26H30ClN3OCouleur et forme :SolidMasse moléculaire :435.989DNA Gyrase-IN-1
DNA Gyrase-IN-1: potent, selective promoter inhibitor. IC50: 2.6 μM, inhibits Mtb, MIC: 0.49 μM. Useful for tuberculosis research.Formule :C24H24FN7O6Couleur et forme :SolidMasse moléculaire :525.49Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Formule :C8H12N2S2Couleur et forme :SolidMasse moléculaire :200.32Antimicrobial agent-38
CAS :<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Formule :C14H11N3O4SCouleur et forme :SolidMasse moléculaire :317.32
