Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3695 produits trouvés pour "Antibactérien"
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CM-728
CAS :CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.Formule :C22H14N2O5Couleur et forme :SolidMasse moléculaire :386.357VEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.48-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41Fostriecin (free base)
CAS :Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Formule :C19H27O9PCouleur et forme :SolidMasse moléculaire :430.39LolCDE-IN-2
CAS :LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40G247
G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.Formule :C24H19Cl2FO3Couleur et forme :SolidMasse moléculaire :445.31Nitrovin
CAS :Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.Formule :C14H12N6O6Couleur et forme :SolidMasse moléculaire :360.28Antibacterial agent 261
CAS :Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).Formule :C18H24N4O3S2Couleur et forme :SolidMasse moléculaire :408.538Kikumycin A
CAS :Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.Formule :C13H17N7O2Couleur et forme :SolidMasse moléculaire :303.32Aurantiogliocladin
CAS :Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.Formule :C10H12O4Couleur et forme :SolidMasse moléculaire :196.2HT1171
CAS :HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.Formule :C7H4N2O4S2Couleur et forme :SolidMasse moléculaire :244.248Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39Rubropunctatin
CAS :Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41RCB18350
CAS :RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.Formule :C19H18F3N3O4SCouleur et forme :SolidMasse moléculaire :441.424Anti-MRSA agent 3
CAS :Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386RNAP-σ interaction inhibitor-2
CAS :RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formule :C27H19Cl3N2O6S2Couleur et forme :SolidMasse moléculaire :637.939MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).Formule :C23H18Cl2FN5OCouleur et forme :SolidMasse moléculaire :470.33RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44BRD-4592
CAS :BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.Formule :C17H15FN2OCouleur et forme :SolidMasse moléculaire :282.312DRF-8417
CAS :DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.Formule :C15H17N3O5SCouleur et forme :SolidMasse moléculaire :351.38
