Antibactérien
Les inhibiteurs antibactériens sont des composés qui ciblent les cellules bactériennes, en inhibant leur croissance ou en les tuant directement. Ces inhibiteurs sont essentiels dans le développement de traitements contre les infections bactériennes et sont largement utilisés dans la recherche pour étudier la physiologie bactérienne, les mécanismes de résistance et l'efficacité de nouveaux agents antibactériens. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs antibactériens pour soutenir vos recherches en microbiologie, maladies infectieuses et développement de médicaments.
3697 produits trouvés pour "Antibactérien"
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PKZ18
CAS :PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.Formule :C22H26N2O3SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :398.518ACHN-975 TFA
CAS :ACHN-975 TFA is a selective inhibitor of the bacterial enzyme LpxC, antimicrobial against multiple Gram-negative bacteria.Formule :C22H24F3N3O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :483.44RCB18350
CAS :RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.Formule :C19H18F3N3O4SCouleur et forme :SolidMasse moléculaire :441.424RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formule :C25H30ClFN2OCouleur et forme :SolidMasse moléculaire :428.97Antibacterial agent 118
Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.Formule :C19H21N5O2SCouleur et forme :SolidMasse moléculaire :383.47BRD-4592
CAS :BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.Formule :C17H15FN2OCouleur et forme :SolidMasse moléculaire :282.312LpxC-IN-10
CAS :LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.Formule :C30H31N5O3Couleur et forme :SolidMasse moléculaire :509.6Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formule :C17H23F3N8O10SCouleur et forme :SolidMasse moléculaire :588.47Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26Antibacterial agent 68
Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.Formule :C26H25BrN4O7Couleur et forme :SolidMasse moléculaire :585.4D-CS319
CAS :D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formule :C7H11NO2S3Couleur et forme :SolidMasse moléculaire :237.36DHFS-IN-1
CAS :DHFS-IN-1 (Compound 3) is an inhibitor of dihydrofolate synthetase (DHFS) with an IC50 of 2.6 μM. It is applicable for research into infectious diseases related to bacterial folate synthesis.Formule :C16H16N8O2Couleur et forme :SolidMasse moléculaire :352.357-Hydroxytropolone
CAS :7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Formule :C16H16N4O5Couleur et forme :SolidMasse moléculaire :344.32K13787
CAS :K13787 is an acetohydroxy acid synthase (AHAS) inhibitor with antibacterial properties. It exhibits antimicrobial activity against various non-tuberculous mycobacteria (NTM) as well as clarithromycin (CLR) resistant strains.Formule :C14H11F2N5O4SCouleur et forme :SolidMasse moléculaire :383.33Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Formule :C20H12ClN3O5Couleur et forme :SolidMasse moléculaire :409.78FR-145715
CAS :FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.Formule :C16H21N5O2SCouleur et forme :SolidMasse moléculaire :347.44LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Formule :C22H19N3O2Couleur et forme :SolidMasse moléculaire :357.41Antibacterial agent 259
CAS :Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.Formule :C7H6ClN3O2SCouleur et forme :SolidMasse moléculaire :231.659
