Antibactérien

<p>Antibacterial agent 153 is a broad-spectrum agent that eradicates bacteria by targeting their cell membranes and is employed in research on bacterial infections</p>

Antibacterial agent 52 (example 18) is a antibacterial agent.

<p>Amustaline (S-303) dihydrochloride is a nucleic acid alkylator useful for inactivating pathogens in blood with red cells.</p>

EDA-DA is a probe for labeling bacterial cell wall Peptidoglycan, crucial for division and shape.

A 83016A is a kinamycin-type antibiotic.

Lankacidins is an antitumor antibiotic of the macrolide tetraenes family from Streptomyces.

<p>Adipic dihydrazide (ADH) is a dihydrazide a bifunctional cross-linking agent for water-in-oil emulsions and a curing agent for epoxy resins.</p>

<p>Mtb-IN-10 (Compound P15) is an Rv1625c/Cya activator that influences the growth of Mycobacterium tuberculosis (Mtb) by modulating cAMP metabolism. It demonstrates an anti-tuberculosis activity with an EC50 of 1.96 µM in Mtb-infected macrophage models and achieves an oral bioavailability of 58.0% when administered orally to mice at 20 mg/kg. Mtb-IN-10 potentially regulates intracellular signaling and disrupts cholesterol metabolism within Mtb, thereby inhibiting bacterial proliferation. It holds promise for tuberculosis (TB) research, particularly targeting multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains of Mtb.</p>

Pyrrole (1H-pyrrole) is a fungicides.

<p>Amicetin, a potent antibiotic, is effective against gram-positive bacteria by inhibiting protein synthesis [1] [2] [3].</p>

β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.

Massarigenin C from M. flavorosea inhibits neuraminidase (IC50=4.15μM) and α-glucosidase (IC50=1.25mM), reduces blood glucose in mice.

Ceftaroline: a cephalosporin antibiotic effective against MRSA, drug-resistant S. pneumoniae, and Gram-negatives; used for cSSSIs and CABP research.

<p>QST4 possessed antitubercular and antifungal activities with a MIC value of 6.25 μM in Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv.</p>

<p>Capoamycin is an insotatracine antibiotic investigated for anti tumor properties.</p>

<p>NDM-1 inhibitor-8 (Compound 18b) is a covalent inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1), with an IC50 of 7.03 μM. It effectively inhibits resistant bacterial strains and demonstrates synergistic antibacterial effects when used in combination with Meropenem. In mouse models, NDM-1 inhibitor-8 exhibits anti-infective activity.</p>

Aurein 2.2, a principal constituent of L.aurea skin secretions, exhibits broad-spectrum antibacterial properties, particularly effective against Gram-positive

<p>Pyrrolnitrin: broad-spectrum antibiotic from Pseudomonas pyrrocinia; effective against fungi, yeast, and gram-positive bacteria.</p>

<p>Aerocyanidin is an antibiotic (antibiotic) that contains an isonitrile group and is primarily effective against Gram-positive bacteria.</p>

<p>Tryptophanase, a bacterial enzyme, catalyzes the degradation of tryptophan into indole, pyruvate, and ammonia [1].</p>