Antibactérien

Oral nitroimidazole antibiotic; treats anaerobic infections; may cause inflammation and muscle contractions with long-term use.

c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.

Demethyl linezolid, an impurity in linezolid (WO199500721A1, ex. 9), has antimicrobial effects on human and veterinary pathogens.

Sitafloxacin (DU6859a) is a potent fluoroquinolone, effective against a wide spectrum of bacteria and used for respiratory and urinary infections.

Cecropin A TFA: a 37-residue peptide from Hyalaphora cecropia, with antibacterial, anti-inflammatory, and anticancer properties.

1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.

Hepcidin-20: human peptide, antifungal, hinders biofilm & bacterial metabolism in PIA+/- strains.

Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.

Sitafloxacin monohydrate (DU6859a) is a potent fluoroquinolone antibiotic with broad-spectrum anti-bacterial and anti-chlamydial effects.

Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins

Uvaretin demonstrates potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM).

Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent.

Maximin 5, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal

Antibacterial agent 55 (example 21) is a antibacterial agent.

Nybomycin, a fungal metabolite from Streptomyces sp. A717, has antibacterial properties; effective against various bacteria including M. tuberculosis.

Razupenem (SMP-601, PTZ601), a broad-spectrum injectable carbapenem, counters antibiotic-resistant bacteria.

Valclavam is a biochemical.

Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and