AMPK
Les inhibiteurs de l'AMPK sont des composés qui ciblent et inhibent la Protéine Kinase Activée par l'AMP (AMPK), une enzyme jouant un rôle crucial dans l'homéostasie énergétique cellulaire. L'AMPK est activée en réponse à de faibles niveaux d'énergie dans les cellules et aide à réguler des processus tels que l'absorption du glucose, l'oxydation des acides gras et la biogenèse mitochondriale. Inhiber l'AMPK est important pour étudier son rôle dans les maladies métaboliques, le cancer et le vieillissement. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de l'AMPK pour soutenir vos recherches sur le métabolisme, l'oncologie et les maladies liées à l'âge.
171 produits trouvés pour "AMPK"
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Doxorubicin hydrochloride
CAS :Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formule :C27H29NO11·HClDegré de pureté :98% - 99.52%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.99RMC-7977
CAS :RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.Formule :C47H60N8O6SDegré de pureté :97.11% - 99.86%Couleur et forme :SolidMasse moléculaire :865.09Ref: TM-T81263
1mg231,00€5mg580,00€10mg888,00€25mg1.378,00€50mg1.783,00€100mg2.512,00€1mL*10mM (DMSO)888,00€MT 63-78
CAS :MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).
Formule :C21H14N2O2Degré de pureté :97.11%Couleur et forme :SolidMasse moléculaire :326.35PT-1
CAS :PT-1 is an AMPKα1 activator that dose-dependently activates AMPK α1394, α1335, and α2398 and enhances AMPK phosphorylation.Formule :C23H16ClN3O6SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :497.91MARK4 inhibitor 1
CAS :MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.Formule :C20H18N6O3Degré de pureté :97.7%Couleur et forme :SolidMasse moléculaire :390.4Mefloquine
CAS :Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.
Formule :C17H16F6N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.31AICAR
CAS :AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!Formule :C9H14N4O5Degré de pureté :98.00% - ≥95%Couleur et forme :SolidMasse moléculaire :258.23Phenformin
CAS :Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.Formule :C10H15N5Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :205.26Urolithin B
CAS :Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormule :C13H8O3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :212.2Flufenamic acid
CAS :Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.
Formule :C14H10F3NO2Degré de pureté :98.68%Couleur et forme :White To Light Yellow Crystalline PowderMasse moléculaire :281.23Miglitol
CAS :Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.Formule :C8H17NO5Degré de pureté :99.75% - 99.88%Couleur et forme :White To Pale-Yellow Powder SolidMasse moléculaire :207.22Danthron
CAS :Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Formule :C14H8O4Degré de pureté :99.51% - 99.97%Couleur et forme :Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Masse moléculaire :240.21MK8722
CAS :MK8722 is an effective and systemic activator of pan-AMPK.Formule :C24H20ClN3O4Degré de pureté :98.08% - 99.8800%Couleur et forme :SolidMasse moléculaire :449.89Ref: TM-T16099
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg226,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)87,00€Phenformin hydrochloride
CAS :Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formule :C10H16ClN5Degré de pureté :97.11% - 99.80%Couleur et forme :Lactic AcidosisMasse moléculaire :241.72Tranexamic acid
CAS :Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Formule :C8H15NO2Degré de pureté :99.64% - 99.79%Couleur et forme :White Crystalline PowderMasse moléculaire :157.21Mefloquine hydrochloride
CAS :Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formule :C17H17ClF6N2ODegré de pureté :99% - 99.99%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :414.77Metformin hydrochloride
CAS :Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formule :C4H12ClN5Degré de pureté :97.53% - 99.97%Couleur et forme :White Or Almost White Crystals Solid CrystallineMasse moléculaire :165.63Chitosan oligosaccharide
CAS :Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.Formule :C12H24N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.327Glycometabolism Compound Library
xnum glycometabolism-related comounds, can be used for HTS and HCT;
Couleur et forme :Odour SolidALKBH1-IN-3
ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.Couleur et forme :Odour SolidSAMS
CAS :SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).Formule :C74H131N29O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1779.15ALKBH1-IN-3 prodrug
ALKBH1-IN-4 prodrug (Compound 29E) is a prodrug of an inhibitor targeting the DNA N6-methyladenine demethylase enzyme ALKBH1. It works by significantly increasing the cellular abundance of 6mA and enhancing the AMPK signaling pathway, which suppresses the vitality of gastric cancer cells. ALKBH1-IN-4 prodrug displays excellent cellular activity and favorable metabolic exposure in vivo, making it a promising candidate for research in gastric cancer-related areas.
Couleur et forme :Odour SolidFluoxetine-Conjugated Platinum(IV) prodrug-1
Fluoxetine-Conjugated Platinum(IV) prodrug-1 is an eEF2K inhibitor that can hinder the proliferation of cancer cells, induce DNA damage, and cause cell cycle arrest at the S phase, leading to apoptosis (Apoptosis). It also promotes the accumulation of reactive oxygen species (ROS) and disrupts mitochondrial function. This prodrug inhibits the migration and invasion of TNBC cells by suppressing MMP-2 activity and induces autophagy in TNBC cells through AMPK activation. In the 4T1-Luc mouse model, it exhibits antitumor activity and triggers immune suppression. Fluoxetine-Conjugated Platinum(IV) prodrug-1 is relevant for research in triple-negative breast cancer (TNBC).Formule :C21H28Cl2F3N3O5PtCouleur et forme :SolidMasse moléculaire :724.1006Biguanide
CAS :Biguanide can reduce oxidative stress in rats with hyperglycemia.Formule :C2H7N5Couleur et forme :SolidMasse moléculaire :101.114-PivO-NMT chloride
CAS :4-PivO-NMT chloride is an indole derivative-based regulator of the AMPK signaling pathway. It modulates neurogenesis or neurite outgrowth by influencing AMPK activity and holds potential for research in neurological disorders, pain, and inflammation.Formule :C16H23ClN2O2Couleur et forme :SolidMasse moléculaire :310.82Foenumoside B
CAS :Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotesFormule :C60H96O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1217.39AMPK activator 15
AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA)-induced lipid accumulation.Formule :C53H51BrNO10PSCouleur et forme :SolidMasse moléculaire :1004.92NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formule :C24H30N6OCouleur et forme :SolidMasse moléculaire :418.535STO-609 acetate
CAS :STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for theFormule :C19H10N2O3·C2H4O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :374.35AMPK activator 13
AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal expansion in 3T3-L1 cells and enhancing mitochondrial oxygenDegré de pureté :98%Couleur et forme :Odour SolidMARK4 inhibitor 2
MARK4 Inhibitor 2 is a potent inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4), exhibiting a Kₘ of 6.3×10⁷ and an IC₅₀ of 0.82 μM.Formule :C34H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :542.63Kanglexin
CAS :Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.Formule :C21H18O8Masse moléculaire :398.36CB1R/AMPK modulator 1
Compound 38-S is an orally active CB1R/AMPK modulator with a K i of 0.81 nM and an IC50 of 3.9 nM for CB1R.Formule :C25H22Cl2N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.45ZLN 024 hydrochloride
CAS :ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).Formule :C13H14BrClN2OSDegré de pureté :98.541%Couleur et forme :SolidMasse moléculaire :361.68UCB9386
UCB9386 is a brain-penetrant and selective inhibitor of Nuak1, with a pIC50 of 10.1. It also inhibits Nuak2 and Kak2, showing approximately 50% inhibition at 10 nM.Formule :C27H26N8OCouleur et forme :SolidMasse moléculaire :478.548Wu-5
CAS :Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.Formule :C15H13NO7SDegré de pureté :99.65%Couleur et forme :SoildMasse moléculaire :351.33GSK-1070916
CAS :GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.Formule :C30H33N7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :507.63AMARA peptide
CAS :AMARA peptide: a minimal substrate for SIK, AMPK, and other protein kinases; contains AMPK phosphorylation site.Formule :C62H115N27O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1542.81Resolvin D3
CAS :Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.Formule :C22H32O5Couleur et forme :SolidMasse moléculaire :376.493AMPK-IN-6
AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 µM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.Formule :C18H20FN5OCouleur et forme :SolidMasse moléculaire :341.383AMPK activator 2 hydrochloride( 2410961-69-0 Free base)
AMPK activator 2 hydrochloride upregulates the AMPK signaling pathway and inhibits the proliferation and migration of human cancer cells.Formule :C13H19ClF3N5Degré de pureté :99.68%Couleur et forme :SoildMasse moléculaire :337.77XY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Formule :C32H34FN3O5Couleur et forme :SolidMasse moléculaire :559.628(E/Z)-10-Hydroxy-2-decenoic acid
CAS :(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences.Formule :C10H18O3Couleur et forme :SolidMasse moléculaire :186.251Flindersine
CAS :Flindersine is a useful organic compound for research related to life sciences. The catalog number is T124718 and the CAS number is 523-64-8.Formule :C14H13NO2Couleur et forme :SolidMasse moléculaire :227.263IQZ23
CAS :IQZ23 inhibits fat cell formation, activates AMPK, cuts triglycerides (EC50=0.033 μM), may aid obesity/metabolic study.Formule :C26H29N5O2Couleur et forme :SolidMasse moléculaire :443.551Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Couleur et forme :Odour SolidHTH-02-006
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells and inhibits YAP-driven cell proliferation, hepatomegaly,Formule :C25H29IN6O3Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :588.45AMPK-Targeted Compound Library
xnum well-chosen unique AMPK-targeted small molecules；Couleur et forme :Odour SolidRef: TM-L1120
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderN,N-Didesethyl Sunitinib
CAS :N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.Formule :C18H19FN4O2Degré de pureté :97.73%Couleur et forme :SoildMasse moléculaire :342.37Ref: TM-T60128
1mg137,00€5mg329,00€10mg464,00€25mg753,00€50mg1.026,00€100mg1.406,00€1mL*10mM (DMSO)338,00€Antidiabetic agent 7
Antidiabetic agent 7 (Compound 5m) functions as a potent hyperglycemia inhibitor. It effectively stimulates GLUT4 translocation in skeletal muscle cells by activating the AMPK-dependent pathway. Additionally, this compound is capable of reducing blood glucose levels and exhibits favorable pharmacokinetic properties. Antidiabetic agent 7 is suitable for research related to antihyperglycemic treatments.Formule :C27H21Cl2N5O3Couleur et forme :SolidMasse moléculaire :534.39NUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formule :C25H30N6OCouleur et forme :SolidMasse moléculaire :430.545Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Couleur et forme :Odour LiquidMetformin-d6 hydrochloride
CAS :Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formule :C4H12ClN5Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :171.666-Azuridine
CAS :6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.
Formule :C8H11N3O6Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :245.19Pyraclostrobin (Standard)
CAS :Pyraclostrobin (Standard) is the standard substance of Pyraclostrobin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formule :C19H18ClN3O4Couleur et forme :SolidMasse moléculaire :387.82Teneligliptin hydrobromide hydrate
CAS :Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Formule :C22H33BrN6O2SCouleur et forme :SolidMasse moléculaire :525.51Nepodin
CAS :Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.Formule :C13H12O3Degré de pureté :97.9% - 99.12%Couleur et forme :SolidMasse moléculaire :216.23Ref: TM-TN1100
1mg54,00€2mg80,00€5mg120,00€10mg192,00€25mg324,00€50mg480,00€100mg683,00€1mL*10mM (DMSO)114,00€Platycodin D
CAS :Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA.Formule :C57H92O28Degré de pureté :99.2% - 99.65%Couleur et forme :SolidMasse moléculaire :1225.32IMM-H007
CAS :IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormule :C22H23N5O8Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :485.45Ref: TM-T9010
1mg40,00€5mg96,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€1mL*10mM (DMSO)131,00€O-304
CAS :O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formule :C16H11Cl2N3O2SDegré de pureté :99.84% - ≥98%Couleur et forme :SolidMasse moléculaire :380.25Ref: TM-T7362
1mg66,00€2mg96,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)159,00€Vaccarin
CAS :Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formule :C32H38O19Degré de pureté :99.16% - 99.97%Couleur et forme :SolidMasse moléculaire :726.63Demethyleneberberine
CAS :Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormule :C19H18NO4Degré de pureté :98.08% - 99.18%Couleur et forme :SolidMasse moléculaire :324.35GSK621
CAS :GSK621 is a specific and potent AMPK activator.Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91Ref: TM-T6854
1mg52,00€2mgÀ demander5mg106,00€10mg180,00€25mg311,00€50mg502,00€100mg743,00€200mg1.026,00€Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.
Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16DASA-58
CAS :DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Formule :C19H23N3O6S2Degré de pureté :96.96% - 99.28%Couleur et forme :SolidMasse moléculaire :453.53Trilobatin
CAS :Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormule :C21H24O10Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)109,00€ARN-3236
CAS :ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFormule :C19H16N2O2SDegré de pureté :98.89% - 99.7%Couleur et forme :SolidMasse moléculaire :336.41Ref: TM-T5993
1mg60,00€5mg97,00€10mg160,00€25mg264,00€50mg354,00€100mg540,00€200mg777,00€1mL*10mM (DMSO)150,00€STO-609
CAS :STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.
Formule :C19H10N2O3Degré de pureté :97.14% - 98.8%Couleur et forme :SolidMasse moléculaire :314.29WH-4-025
CAS :WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formule :C39H38F3N7O5Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :741.76Ref: TM-T9219
1mg40,00€2mg52,00€5mg88,00€10mg137,00€25mg264,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)87,00€AMAROGENTIN
CAS :Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Formule :C29H30O13Degré de pureté :99.98% - ≥95%Couleur et forme :SolidMasse moléculaire :586.54EB-3D
CAS :EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formule :C30H36Br2N4O2Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :644.4Ref: TM-T7955
1mg92,00€2mg120,00€5mg187,00€10mg274,00€25mg472,00€50mg655,00€100mg924,00€200mg1.225,00€1mL*10mM (DMSO)278,00€AMPK activator 2
CAS :AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formule :C13H18F3N5Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :301.31BC1618
CAS :BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formule :C24H24F3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :415.45Pyraclostrobin
CAS :Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formule :C19H18ClN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :387.82Buformin
CAS :Buformin, a biguanide oral antidiabetic, inhibits liver glucose production and improves insulin sensitivity.Formule :C6H15N5Couleur et forme :SolidMasse moléculaire :157.22Ginkgolide C
CAS :Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formule :C20H24O11Degré de pureté :99.71% - 99.98%Couleur et forme :White PowderMasse moléculaire :440.40MK-3903
CAS :MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formule :C27H19ClN2O3Degré de pureté :98.63% - 99.75%Couleur et forme :SolidMasse moléculaire :454.9Ref: TM-T5187
1mg35,00€5mg80,00€10mg120,00€25mg188,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)88,00€IMT1
CAS :IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formule :C21H21NO4Degré de pureté :98.07% - 98.14%Couleur et forme :SolidMasse moléculaire :351.4Ref: TM-T8841
1mg77,00€5mg166,00€10mg285,00€25mg533,00€50mg763,00€100mg1.054,00€1mL*10mM (DMSO)178,00€Kahweol
CAS :Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42Dorsomorphin dihydrochloride
CAS :Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormule :C24H25N5O·2HClDegré de pureté :97.74% - 99.89%Couleur et forme :SolidMasse moléculaire :472.41Ref: TM-T6146
2mg35,00€5mg51,00€10mg70,00€25mg135,00€50mg235,00€100mg424,00€500mg938,00€1mL*10mM (DMSO)57,00€COH-SR4
CAS :COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formule :C13H8Cl4N2ODegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :350.03Marein
CAS :Marein prevents PC12 cell damage by protecting mitochondria and activating AMPK, potentially countering diabetic encephalopathy.Formule :C21H22O11Degré de pureté :99.12% - 99.84%Couleur et forme :SolidMasse moléculaire :450.39Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14Dorsomorphin
CAS :Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formule :C24H25N5ODegré de pureté :98% - 99.06%Couleur et forme :SolidMasse moléculaire :399.49Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :SolidMasse moléculaire :344.49Ref: TM-T3625
2mg35,00€5mg52,00€10mg73,00€25mg125,00€50mg217,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)55,00€Mogroside I E1
CAS :Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Formule :C36H62O9Degré de pureté :98.62% - 99.71%Couleur et forme :SolidMasse moléculaire :638.87Teneligliptin hydrobromide
CAS :Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formule :C22H30N6OSBrHDegré de pureté :97.83% - 99.92%Couleur et forme :SolidMasse moléculaire :628.86Flurbiprofen Axetil
CAS :Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formule :C19H19FO4Degré de pureté :97.58% - 98%Couleur et forme :SolidMasse moléculaire :330.35STF-118804
CAS :STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formule :C25H23N3O4SDegré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :461.53SBI-0206965
CAS :SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
Formule :C21H21BrN4O5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :489.32Gomisin J
CAS :Gomisin J is a natural product and have vasodilatory activity.Formule :C22H28O6Degré de pureté :99.59% - 99.60%Couleur et forme :SolidMasse moléculaire :388.45Ref: TM-T3904
1mg47,00€2mg65,00€5mg119,00€10mg188,00€25mg329,00€50mg490,00€100mg700,00€1mL*10mM (DMSO)97,00€GSK-690693
CAS :GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formule :C21H27N7O3Degré de pureté :98.07% - 99.77%Couleur et forme :SolidMasse moléculaire :425.48RSVA405
CAS :RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormule :C17H20N4O2Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :312.37MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formule :C103H156N28O24S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :2234.64WZ4003
CAS :WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formule :C25H29ClN6O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :496.99Ref: TM-T6291
5mg50,00€10mg77,00€25mg117,00€50mg170,00€100mg255,00€200mg378,00€500mg622,00€1mL*10mM (DMSO)52,00€PKC-iota inhibitor 1
CAS :PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T8764
1mg113,00€2mg160,00€5mg230,00€10mg369,00€25mg615,00€50mg879,00€100mg1.198,00€500mg2.395,00€1mL*10mM (DMSO)240,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formule :C26H37ClN6O2Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :501.07ON123300
CAS :ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formule :C24H27N7ODegré de pureté :99.53% - 99.7%Couleur et forme :SolidMasse moléculaire :429.52Metformin glycinate
CAS :Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Formule :C6H16N6O2Couleur et forme :SolidMasse moléculaire :204.23[6]-Gingerol
CAS :[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Formule :C17H26O4Degré de pureté :98% - 99.66%Couleur et forme :Light Yellow OilinessMasse moléculaire :294.39
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