AMPK
Les inhibiteurs de l'AMPK sont des composés qui ciblent et inhibent la Protéine Kinase Activée par l'AMP (AMPK), une enzyme jouant un rôle crucial dans l'homéostasie énergétique cellulaire. L'AMPK est activée en réponse à de faibles niveaux d'énergie dans les cellules et aide à réguler des processus tels que l'absorption du glucose, l'oxydation des acides gras et la biogenèse mitochondriale. Inhiber l'AMPK est important pour étudier son rôle dans les maladies métaboliques, le cancer et le vieillissement. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de l'AMPK pour soutenir vos recherches sur le métabolisme, l'oncologie et les maladies liées à l'âge.
161 produits trouvés pour "AMPK".
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Resolvin D3
CAS :Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.Formule :C22H32O5Couleur et forme :SolidMasse moléculaire :376.493AMARA peptide
CAS :AMARA peptide: a minimal substrate for SIK, AMPK, and other protein kinases; contains AMPK phosphorylation site.Formule :C62H115N27O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1542.81SAMS
CAS :SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).Formule :C74H131N29O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1779.15NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formule :C24H30N6OCouleur et forme :SolidMasse moléculaire :418.535ALKBH1-IN-3
ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.Couleur et forme :Odour SolidKanglexin
CAS :Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.Formule :C21H18O8Couleur et forme :SolidMasse moléculaire :398.36Glycometabolism Compound Library
xnum glycometabolism-related comounds, can be used for HTS and HCT;Couleur et forme :Odour SolidRef: TM-L2520
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderXY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Formule :C32H34FN3O5Couleur et forme :SolidMasse moléculaire :559.628N,N-Didesethyl Sunitinib
CAS :N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.Formule :C18H19FN4O2Degré de pureté :97.73%Couleur et forme :Orange SolidMasse moléculaire :342.37Ref: TM-T60128
1mg130,00€5mg313,00€1mL*10mM (DMSO)319,00€10mg439,00€25mg713,00€50mg973,00€100mg1.333,00€Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Couleur et forme :Transparent LiquidMetformin-D6 hydrochloride
CAS :Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formule :C4H12ClN5Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :171.66Teneligliptin hydrobromide hydrate
CAS :Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Formule :C22H33BrN6O2SCouleur et forme :SolidMasse moléculaire :525.516-Azuridine
CAS :6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.Formule :C8H11N3O6Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :245.19BC1618
CAS :BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formule :C24H24F3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :415.45O-304
CAS :O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formule :C16H11Cl2N3O2SDegré de pureté :99.84% - ≥98%Couleur et forme :White SolidMasse moléculaire :380.25Ref: TM-T7362
1mg63,00€2mg92,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€Kahweol
CAS :Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42AMPK activator 2
CAS :AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formule :C13H18F3N5Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :301.31Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16Ref: TM-T8526
10mg44,00€1mL*10mM (DMSO)44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€Flurbiprofen Axetil
CAS :Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formule :C19H19FO4Degré de pureté :97.58% - 98%Couleur et forme :SolidMasse moléculaire :330.35EB-3D
CAS :EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formule :C30H36Br2N4O2Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :644.4Ref: TM-T7955
1mg87,00€2mg114,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)263,00€25mg447,00€50mg620,00€100mg875,00€200mg1.161,00€
