Oligosaccharides

<p>Tetra-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-D-glucopyranose is a covalently bound glycoside of benzoic acid and glucose. It can be obtained by the chemical catalysis of clostridium in an acetate medium. The reaction produces a tetrasaccharide with three acetate groups at C2, C3 and C6. This compound has shown to have antimicrobial activity against Clostridium licheniformis and Clostridium butyricum.</p>

<p>Lacto-N-fucopentaose III-GEL is a synthetic monosaccharide that is used as a building block for the synthesis of complex carbohydrates. Lacto-N-fucopentaose III-GEL is synthesized from fructose, which is methylated with chloromethylated N,N'-diacetylchitobiose as the methylating agent and sodium methoxide as the catalyst. The resulting glycoconjugate is then treated with hydrofluoric acid to introduce fluorine atoms into the carbohydrate backbone.</p>

<p>Lacto-N-fucopentaose III-APD-HSA is a custom synthesis, complex carbohydrate that has been modified with methylation and glycosylation. It is an oligosaccharide that is found in human serum albumin. Lacto-N-fucopentaose III-APD-HSA has been shown to have antitumor activity. It also inhibits the growth of bacteria by binding to bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. This compound binds to two sites on the 16S ribosomal RNA of bacteria and can inhibit protein synthesis, leading to cell death by inhibiting production of proteins vital for cell division. Lacto-N-fucopentaose III-APD-HSA has undergone fluorination and click modification.<br>Methylation: A process whereby a methyl group (-CH3) is added to an organic molecule via a chemical</p>

<p>Hyaluronate fluorescein is a synthetic, high purity, custom-synthesized molecular weight of 50kDa. It is a complex carbohydrate with a sugar backbone and many attached monosaccharides. Hyaluronate fluorescein has been modified by methylation and glycosylation. This product can be used for fluorescent labeling of oligosaccharides and carbohydrates.</p>

<p>Chondroitin sulphate hexasaccharide ammonium salt is a synthetic glycoconjugate that is used as a drug for the treatment of osteoarthritis and other joint diseases. It is a complex carbohydrate consisting of glucuronic acid, galactose, N-acetylgalactosamine, and sulfate residues. Chondroitin sulphate hexasaccharide ammonium salt has high purity and can be custom synthesized to your specifications. This product is methylated with an acetyl group at carbon 6. The monosaccharides are modified by glycosylation with glucose or mannose residues. Chondroitin sulphate hexasaccharide ammonium salt has been click-modified to include a carboxylic acid moiety on the primary amine group at carbon 2 and an amino group on the terminal amino group at carbon 3.</p>

<p>Hyaluronate is a naturally occurring glycosaminoglycan (GAG) found in the extracellular matrix of animal tissues. It is a linear polymer composed of alternating units of N-acetylglucosamine and glucuronic acid. The molecular weight of hyaluronate ranges from 10,000 Da to 1,000,000 Da. Hyaluronate has been modified by fluorination, methylation, and click modification reactions. These modifications affect the physical properties of hyaluronate, including its reactivity with other molecules. Click modification reactions are often used to link two different molecules together. This may include linking an oligosaccharide or saccharide to the hydroxyl groups on the glucuronic acid residues in hyaluronate.</p>

<p>4-Methoxyphenyl 4-O-[6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-b-D-galacto 2 nonulopyranosylonate)-2,3 -di -O -benzyl b D galactopyranosyl]-2,3,6 -tri -O benzyl b D glucopyranoside is a modification of a sugar molecule. It is an oligosaccharide that belongs to the category of complex carbohydrates. The sugar is synthesized from monosaccharides and polysaccharides. The chemical name for the sugar is 4 methoxyphenyl 4 O-[6 O (methyl 5 acetamido 4 7 8 9 tetra O acetyl 3 5 dideoxy D glycero b D galacto 2 nonul</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>1,3-α-D-mannopyranosyl trichloroacetimidate (1,3-α-DMTCA) is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. The synthesis of 1,3-α-DMTCA involves the reaction of α,β-unsaturated chloral hydrate with mannose in aqueous solution. This produces an intermediate product that undergoes glycosylation with glycosylation reagents like glycosyl chloride to yield 1,3-α-DMTCA. The chemical structure of 1,3-α-DMTCA can be modified by various reactions including methylation or click modification. 1,3 DMTCA is also available as a high purity material.<br>1,3 α - D - mannosyltetrahydrochlorofonuimidoksyl</p>

<p>O-(Methyl b-d-glucopyranosyluronate)-(1,3)-2-amino-2-deoxy-D-galactopyranose HCl is a synthetic monosaccharide with a molecular weight of 338.18 g/mol. It has very high purity and can be custom synthesized to suit customer needs. This product is used in glycosylation reactions and as a sugar donor in click chemistry reactions.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-benzyl-b-D-galactopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is made up of a saccharide and a sugar. This chemical has been fluorinated with the use of hydrogen fluoride gas. The chemical also has methyl groups that have been added to it. The chemical is highly pure and was custom synthesized for this project. This chemical can be used in glycosylation or click chemistry.</p>

<p>1,2,3-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-b-D-galactopyranoside is an oligosaccharide with a galactosamine residue at the nonreducing end. It is a triacylglycerol that has been methylated and fluorinated. This product can be used as a sugar for synthesis of complex carbohydrates or for modification of monosaccharides. The high purity of this product makes it suitable for use in pharmaceuticals and other applications requiring high purity.</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>4-Methoxyphenyl 4-O-(3-O-allyl-b-D-galactopyranosyl)-3-O-allyl-b-D-glucopyranoside is a custom synthesis product that is used as a synthetic intermediate in the modification of complex carbohydrates. This product is a fluorinated sugar, with a high purity and high quality. It has been modified to include methyl groups at specific positions on the sugar molecule. The CAS number for this product is 8721401.</p>

<p>Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-ethylamine is a glycosylation agent that is used to modify complex carbohydrates, such as polysaccharides and oligosaccharides. This product is a custom synthesis, which may be modified according to customer specifications. These modifications include methylation, click modification, fluorination, and saccharide modification. The desired purity of this product can be determined by the level of fluorescence in the solution.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-a-D-galactopyranose is a high purity, custom synthesis of an oligosaccharide consisting of a complex carbohydrate. The saccharide is modified with methylation and glycosylation. This product has been fluorinated and synthesized through the Click chemistry.</p>

<p>Lewis X is a glycoprotein found on the surface of red blood cells and is composed of a trisaccharide that is covalently attached to the protein. It is expressed in the cells of all individuals, but at different levels depending on their blood group. Lewis X is an antigen for monoclonal antibody, which recognizes it by binding to its sugar residues. The antibody can be used to detect Lewis X-expressing cells in the blood and for cancer diagnosis. Antibodies against Lewis X can also be used to inhibit tumor growth by enhancing natural killer cell activity and killing tumor cells.</p>

<p>4-Methoxyphenyl 6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonate)-2,3 -di O benzyl b D galactopyranoside is a modified oligosaccharide that is synthesized from the sugar galactose. The methyl group on the 4 position of the phenol end of the molecule is substituted with an acetamide group to form 4 methoxyphenyl 6 O (methyl 5 acetamido 4 7 8 9 tetra O acetyl 3 5 dideoxy D glycero a D galacto 2 nonulopyranosylonate)-2 3 di O benzyl b D galactopyranoside. This molecule has been fluorinated at the 2 and 3 positions</p>

<p>Primeverose is a p-hydroxybenzoic acid that is found in the genus Primula and mammalian tissue. Primeverose has been shown to inhibit the activity of an enzyme called fatty acid activated, which is involved in the biosynthesis of anthraquinone glycosides. Primeverose is also able to hydrolyze enzymes such as primeverose and may act as a signal peptide for biological samples. The hydroxyl group on primeverose can form hydrogen bonds with other molecules and is present in food composition.</p>

<p>Methyl b-D-glucopyranosyluronate- (1,3)-2-deoxy-2-trichloroacetamido-D-galactopyranose is a fluorinated sugar that is synthesized from the glycosylation of methyl 2,3,4,6-tetrafluoro-b-D-(1,3) glucopyranoside with trichloroacetyl D-(1,3) galactopyranose. This compound is soluble in water and has a CAS number of 1058858. This product can be used as a reagent for glycosylation reactions such as Click chemistry and Methylation. It also has applications in carbohydrate modification and high purity custom synthesis.</p>