Oligosaccharides

Chitosan oligomer (Dp 12-20) is a modification of chitin, a polysaccharide. It can be synthesized by treating chitin with sodium hydroxide in an alkaline environment. Chitosan oligomer (Dp 12-20) has a high degree of saccharide modification and exhibits a variety of functions, including complex carbohydrate, custom synthesis, synthetic, high purity, CAS No., and monosaccharide methylation. This compound has been shown to inhibit the growth of bacteria such as Staphylococcus aureus and Clostridium perfringens.

Dermatan sulphate hexasaccharide ammonium salt is a complex carbohydrate modified with an oligosaccharide. Dermatan sulfate hexasaccharide ammonium salt is a synthetic, high purity chemical produced by custom synthesis. This compound has CAS No. 849-27-6. It is a monosaccharide that can be methylated and glycosylated to form polysaccharides of different lengths and configurations. Dermatan sulfate hexasaccharide ammonium salt is a sugar that can be fluorinated or saccharified to produce compounds of varying molecular weights and properties.

Non-reducing sucrose analog containing glucose and fructose; prebiotic fibre

6'-Sialyllactose is found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. It suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses and inhibits binding of cholera toxin.

N-Acetylallolactosamine is a lectin that has been shown to have an acceptor for the oligosaccharide, n-acetylllactosamine. It is synthesized by alkaline hydrolysis of allolactose, which is a lactose metabolite. N-Acetylallolactosamine can be used as a growth factor in the treatment of wounds and burns. This protein can also be used as a diagnostic tool to detect different types of cells in the blood stream.

This compound is a custom synthesis for Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide and saccharide. It has CAS No. and Polysaccharide as Carbohydrate. The molecular weight of this compound is

Fructooligosaccharide is a natural carbohydrate that is used in dietary supplements and as an additive to food products. It is a prebiotic, meaning it stimulates the growth of beneficial bacteria in the colon. Fructooligosaccharide has been shown to be effective against bowel disease by up-regulating protein genes and enzyme activities. Fructooligosaccharide also has significant anti-inflammatory properties. The anti-inflammatory effects may be due to its ability to inhibit prostaglandin synthesis.

Chondroitin disaccharide di-diSD trisodium salt is a synthetic, high purity chondroitin sulfate with a molecular weight of about 1 million. It is custom synthesized and modified to include a Click modification on the sugar, fluorination, glycosylation and methylation. The CAS number for this product is 149368-03-6. This product can be used as an ingredient in pharmaceuticals or in cosmetics.

Intermediate in synthesis of ganglioside GD2

2-Acetamido-4-O-[2-acetamido-4-O-(b-D-glucopyranosyl)-3,6-di-O-(a-D-mannopyranosyl)-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2 deoxy -b D thioglucopyranose is a carbohydrate that belongs to the class of saccharides. This compound is modified with fluorination and methylation and can be custom synthesized. It has high purity and can be glycosylated or click modified.

Maltohexaose is a polysaccharide formed by 6 units of glucose and can be metabolised inside the cell to a substrate-based inhibitor of fucosyltransferases. It can also be converted to GDP-2-deoxy-2-fluoro-L-fucose, a competitive inhibitor of α-1,3-fucosyltransferase. Matohexaose is used as acceptor for measuring the activity of 4-Alpha-Glucanotransferase.

The acetolysis of carrageenan produces a polymer homologous series of oligosaccharides, [Gal α1,3 Gal, Gal β1,4 Gal], [Gal α1,3 Gal β1,4 Gal, Gal β14, Gal α1,3 Gal], [Gal α1,3 Gal β1,4 Gal α1,3 Gal, Gal β1,4Gal α1,3Gal β1,4Gal] etc. (Lawson, 1968). This is significant as it provides an entry to the α-gal series or Galili antigens due to the fact that the disaccharide Galα1,3 Gal can be isolated in quantity. The distribution of the full α-gal epitope (Galα1-3Galβ1-4GlcNAc-R) is unique in mammals, being abundantly expressed on glycoconjugates of non-primate mammals, prosimians and New World monkeys. In contrast, the α-gal epitope is not expressed on glycoconjugates of Old World monkeys, apes and humans; instead, they produce the natural anti-Gal antibody that specifically binds the α-epitope. Anti-Gal mediates the rejection of pig xenograft organs in humans and monkeys by binding α-gal epitopes on the pig cells, inducing complement mediated destruction and antibody dependent cell mediated destruction. This barrier to xenotransplantation has been eliminated by producing α1,3 glycosyltransferase to knockout pigs. Since anti-Gal is ubiquitous in humans, the α-gal epitope has clinical potential in the production of vaccines expressing α-epitopes that can be targeted to antigen presenting cells (APC), thereby increasing the immunogenicity of viral and other microbial vaccines (Macher, 2008).

The chemical structure of this compound is composed of a custom synthesis, modification, and fluorination. The molecular weight is 572.6 g/mol and the CAS No. is 1027152-06-6. The molecular formula is C50H76O24. This compound has a molecular weight of 572.6 g/mol and an empirical formula of C50H76O24. It appears as a white crystalline powder that can be dissolved in water or ethanol.=END>>

Heparin-derived dp10 saccharide ammonium salt is a glycosylation product of heparin. This compound is synthesized by the treatment of heparin with a fluorinating agent, such as N-fluoro-N'-(2-chloroethyl)peroxycarbonyl chloride or N-fluoro-N'-(2-bromoethyl)peroxycarbonyl chloride, followed by reaction with an amine. The compound can be modified for specific applications through the use of click chemistry, which allows for the selective modification of either the sugar or side chain of the molecule. This product has been characterized and shown to have high purity and a CAS number.

Synthetic building block for oligosaccharide synthesis

Lewis Y pentasaccharide is a carbohydrate antigen that is expressed on the surface of cells in the cancer, tissue and lymphatic system. It has been shown to be a polyvalent carbohydrate ligand for lectins, which are proteins that bind carbohydrates. Lewis Y pentasaccharide has a high affinity for erythrocytes of blood group A and B, which makes it useful as an antigen for detection of these blood groups. The binding of Lewis Y pentasaccharide to glycolipids on tumor cells initiates complement-dependent cytotoxicity (CDC) by activating the classical pathway of the immune system. CDC can be used as an adjuvant therapy in cancer treatment.

Detergent used for the solubilization of membrane proteins.  Important for the solubilization is the detergent-to-protein ratio. At low ratios (1:10) the membranes are lysed and large complexes of are formed containing protein, detergent, and membrane lipids. With progressively larger ratios smaller complexes are obtained. Finally, at ratios of 10:1 to 20:1 individual detergent-protein complexes are formed free of membrane lipids. To determine the optimal conditions it is important to vary both the detergent and the protein concentration (EMBL).