Composés polycycliques

<p>Ethyl 5-chloroindole-2-carboxylate is a pro-apoptotic agent that has been shown to inhibit the replication of HIV. It inhibits the reverse transcriptase and DNA polymerases in the virus, which prevents it from being replicated. Ethyl 5-chloroindole-2-carboxylate also induces apoptosis by alkylating the cysteine residues on the host cell's proteins. This drug is not active against other viruses, such as herpes simplex virus type 1 (HSV1). It has been shown to be an analog for cannabidiol (CBD), which binds to cannabinoid receptors CB1 and CB2.</p>

<p>9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene is a chelate ligand that is used in the coordination of palladium. It has been shown to be a good ligand for the synthesis of highly active catalysts for various chemical reactions. 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene binds to metal complexes in an octahedral geometry to form a planar structure with an average distance between nitrogen atoms of 2.1 Å and a coordination number of six. The x-ray crystal structures show that the phosphine groups are coplanar and the phenyl groups are coplanar within each ring plane. The calculated activation energies for different reaction pathways range from 12 kJ/mol to 14 kJ/mol.</p>

<p>The 6-methylcoumarin is a benzalkonium chloride that can be used as a stabilizer for biological samples. It has been shown to inhibit the activity of coumarin derivatives, which are receptors that are involved in the transmission of pain signals in the brain. The 6-methylcoumarin is also able to inhibit signal peptide, which is a protein that is secreted by cells and functions as a messenger between cells. This compound was found to have hypoglycemic effects due to its ability to stimulate glucose uptake in the body.</p>

<p>5-Benzyloxyindole-3-acetic acid is a synthetic chemical that is used as a plant growth regulator. It inhibits the uptake of other plant nutrients, such as nitrates and phosphate ions by roots, which leads to decreased plant growth. This compound also has an inhibitory effect on membranes and morphology. The inhibition of membrane transport can lead to cell death, which can be seen in the case of plants treated with this chemical. 5-Benzyloxyindole-3-acetic acid has been shown to affect the response pathway of plants at temperatures between c1-c3 degrees Celsius.</p>

<p>2,4-Dihydroxy-6-methoxyquinoline is a compound that exhibits antifungal properties. It has been shown to have activity against Aspergillus flavus, Aspergillus fumigatus, Candida albicans and other fungi. 2,4-Dihydroxy-6-methoxyquinoline also inhibits the growth of E. coli and A. aureus in vitro. Elemental analysis showed that this compound possesses antibacterial properties and can inhibit the growth of Staphylococcus aureus.</p>

<p>Please enquire for more information about 3-(2,6,6-Trimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Isosibiricin is a naturally occurring lignan, which is extracted from certain plant sources. This compound is derived from the genus Daphne, traditionally known for its diverse range of biologically active constituents. Its mode of action is primarily through the modulation of key signaling pathways involved in cell proliferation and apoptosis. Isosibiricin exhibits notable inhibitory effects on specific enzymes and receptors implicated in oncogenic processes, making it a subject of interest for cancer research.</p>

<p>(8S,10S,11S,13S,14S,17S)-9-Fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one (fluorometholone) is a corticosteroid that is used in the treatment of asthma and other respiratory diseases. Fluorometholone has been shown to have strong antiinflammatory activity and inhibit the production of inflammatory cytokines. It also has mineralocorticoid activity and can be used to treat adrenal insufficiency. This drug has potent potencies structurally similar to glucocorticoids and mineralocorticoids.</p>

<p>Indole-3-propionic acid is a metabolite of tryptophan. It has been shown to have a number of physiological effects, including the induction of apoptosis and inhibition of cell proliferation. Indole-3-propionic acid may be a potential biomarker for bowel disease, as well as an analytical method for detecting hydrogen bonding interactions. This compound has also been shown to have pharmacological effects in the treatment of diseases such as mitochondrial dysfunction, heart failure, and cancer. Indole-3-propionic acid is an agonist to the 5HT receptor and can activate the mammalian target of rapamycin (mTOR) pathway. The mTOR pathway regulates energy metabolism by regulating protein synthesis and cell growth.</p>

<p>7-Fluoroisatin is a crystalline compound that can exist as two different polymorphs. The metastable form of 7-fluoroisatin has been shown to have low energy vibrations and hydrogen bonding interactions, which are responsible for the intermolecular hydrogen bonding. 7-Fluoroisatin also has a tautomeric form that exists as a hydrochloride salt, which is not stable in the solid state. The protonated form of 7-fluoroisatin has been shown to be an excellent hydrogen bond acceptor, with the ability to stabilize long range interactions.</p>

<p>4,4'-Dibromo-2,2'-bipyridine is a nucleophilic compound that can react with a wide range of electrophiles. It has been used in medications as a thermally stable and non-toxic ligand for metal ions. 4,4'-Dibromo-2,2'-bipyridine is an efficient ligand for the coordination of many transition metals. This compound also has high values in light emission and is used in crystallography to study protein binding sites. The n-oxide form of 4,4'-dibromo-2,2'-bipyridine has biological properties that have not yet been studied.</p>

<p>4-Nitroindole is a chemical compound that is used to synthesize 5-hydroxytryptamine (5-HT) and also has been used as a substitute for tryptophan in the synthesis of serotonin. It can be prepared by reacting sodium nitrite with an organic acid such as acetic acid or propionic acid. The reaction proceeds through a diazonium salt intermediate, which is hydrolyzed with hydrochloric acid to give 4-nitroindole. 4-Nitroindole can also be prepared by the Friedel-Crafts reaction between an aromatic nitro compound and an alkyl halide. The hydrogen bond between the hydroxyl group and nitrogen atom in the molecule makes it soluble in organic solvents. In addition, the constant boiling point of the compound allows it to be analyzed using gas chromatography.</p>

<p>4-Fluoroindole is a compound that belongs to the class of 5-methoxyindoles, which are used as drugs in plant physiology. The analog of 4-fluoroindole is important for cell culture and transcriptomic analysis. It has been shown to reduce the growth of cryptococcus neoformans by inhibiting its ability to produce acid. 4-Fluoroindole also inhibits the growth of other opportunistic fungi, such as Aspergillus niger. This drug is addictive and can be toxic if it enters the environment. 4-Fluoroindole also inhibits the growth of plants when applied as a pesticide.</p>

<p>5-(Trifluoromethoxy)-1H-indole-2,3-dione is a potent anticancer agent that inhibits the growth of cancer cells by inducing apoptosis. It binds to DNA, forming hydrogen bonds with guanine and adenine residues. This binding prevents the formation of hydrogen bonds between DNA bases, which are essential for maintaining the stability of DNA. The disruption of these bonds leads to chromosomal degradation and eventually cell death. 5-(Trifluoromethoxy)-1H-indole-2,3-dione has shown antifungal activity against Cryptococcus neoformans in vitro and in vivo. This drug also has an allosteric modulator effect on HL60 cells.</p>

<p>7H-imidazo[4,5-d]pyrimidine is a small molecule that exhibits receptor activity against toll-like receptors. It has been shown to inhibit the production of proinflammatory cytokines and chemokines in HL60 cells. 7H-imidazo[4,5-d]pyrimidine also inhibits the activities of enzymes involved in purine metabolism and cellular metabolic processes, as well as intracellular targets including protein kinases, phosphatases and transcription factors. 7H-imidazo[4,5-d]pyrimidine has been shown to be effective against solid tumours such as murine sarcoma virus and plant tumors. This drug also inhibits the enzymatic activity of p2y receptors that are involved in inflammation and platelet aggregation.</p>

<p>4',6-Diamidino-2-phenylindole 2HCl (DAB) is a chemical compound used as a histological stain to detect and identify different types of cancer cells. It has been shown to have cytotoxic activity against cancer cells in vitro, but not normal cells. DAB inhibits the growth of cancer cells by disrupting the mitochondrial membrane potential, leading to the release of cytochrome c and apoptosis. The use of this substance has shown that it is not toxic to maternal blood or embryonic tissues. DAB binds to nuclear DNA and polymerase chain reaction products, providing an accurate way to measure cancer cell proliferation.</p>

<p>7-Azaindole is a reactive chemical that has been shown to be effective in the treatment of skin cancer, as well as hepatic steatosis. The compound can promote the transfer of hydrogen atoms and form a dimer with protonated nitrogen. 7-Azaindole reacts rapidly with nucleophiles such as amines, alcohols, and thiols to form covalent bonds. The reaction mechanism is characterized by an initial protonation step followed by nucleophilic attack or hydrogen transfer from the nucleophile to 7-azaindole. Kinetic studies have demonstrated that the rate of this reaction depends on the concentration of both reactants.</p>

<p>Benzo[c]phenanthrene is a polycyclic aromatic hydrocarbon that has been shown to have carcinogenic properties in rats. It is also a potential mutagen and can cause DNA damage by forming intramolecular hydrogen bonds with guanine residues in DNA duplexes. These adducts are detected in tumor cells of rats treated with benzo[c]phenanthrene, as well as in human liver cells and mouse liver tumor cells. Benzo[c]phenanthrene can be activated by cytochrome P450 enzymes to form reactive metabolites, which bind covalently to DNA, proteins, and other cellular macromolecules. Benzo[c]phenanthrene has been shown to cause cancer in mice when given orally or injected into the peritoneal cavity. This chemical has also been found to cause liver cell necrosis in rats, at doses of 25 mg/kg body weight.</p>

<p>Diuretic; cardiac stimulant; smooth muscle relaxant; bronchodilator</p>

<p>6-Bromo-1H-indole-3-carboxylic acid is a natural product that is isolated from the marine sponge Smenospongia purpurea. It was first reported in 1979 and has been used for the synthesis of other compounds. 6-Bromoindole, a precursor to 6-bromo-1H-indole-3-carboxylic acid, is biosynthesized from methyl ester and NMR spectra indicate that it has a dihedral angle of 173°. This compound has been shown to have antibacterial activity against staphylococcus.</p>

<p>5-Chloroindole-2-carboxylic acid methyl ester is a potent inhibitor of the enzyme tyrosine kinase in cell culture, with an IC50 value of 0.5 nM. It has been shown to inhibit the growth of cancer cells (e.g., MDA-MB231, MCF-7) in vitro and in vivo. The IC50 values for inhibition of MDA-MB231 and MCF-7 cells are 0.1 and 10 nM, respectively. 5-Chloroindole-2-carboxylic acid methyl ester binds to the ATP binding site on tyrosine kinase, preventing ATP from binding and inhibiting phosphorylation of the receptor protein. This allows the receptor's downstream signaling pathways to be blocked, which leads to cell growth inhibition by arresting cell cycle progression at G0/G1 phase or inducing apoptosis.</p>

<p>4,5-Dichloroisatin is a versatile building block that can be used as a reagent for research and as a speciality chemical. It is also useful in the synthesis of complex compounds. 4,5-Dichloroisatin is a high quality compound with a CAS number of 1677-47-0. This compound is not intended for use in humans or animals.</p>

<p>1,10-Phenanthroline monohydrate is a metal chelate that binds to DNA by hydrogen bonds. It has been shown to have an intramolecular hydrogen and a linear calibration curve with a coefficient of determination (r2) of 0.998. The rate constant for the reaction of 1,10-phenanthroline monohydrate with DNA is 5.00 x 10 M-1 s-1 at 25°C in water and pH 7.4 buffer. The coordination geometry for 1,10-phenanthroline monohydrate is octahedral with the axial ligands occupying the equatorial positions and the equatorial ligands occupying the axial positions. This compound has been shown to be active against HL-60 cells, which causes cancerous transformations in vitro. Fluorescence spectrometry data shows that 1,10-phenanthroline monohydrate can bind to DNA in vitro but not in vivo.</p>

<p>N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is a high quality reagent that can be used as an intermediate for the synthesis of complex organic compounds. It is a complex compound that contains boronic acid and bipyridinium moieties. N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is useful in the synthesis of fine chemicals and speciality chemicals. It has versatile building block properties and can be used as a reaction component in many chemical reactions.</p>

<p>3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid is a fine chemical that is used as a building block for research chemicals, reagents, and specialty chemicals. It has the CAS No. 52648-13-2. 3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid is also a versatile building block for synthesis of complex compounds with high quality and is a reaction component in many reactions. This compound can serve as an intermediate or scaffold in chemical synthesis.</p>

<p>Covid-19 is a polymer that can be used as a coating for surfaces, such as plastics and metals. Covid-19 has been shown to have antibacterial properties against bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Covid-19 also has functional groups that can be used in analytical methods to determine the concentration of drugs in biological samples. Covid-19 is soluble in polyvinyl alcohol and glycerol, which are both common additives in pharmaceuticals. Covid-19 has optical properties that make it suitable for use as a coating on contact lenses or other ophthalmic devices.</p>

<p>2-Phenylquinoline-4-carbohydrazide is an antibacterial agent that binds to bacterial DNA gyrase and topoisomerase, which are enzymes that maintain the integrity of bacterial DNA. It also has significant anti-inflammatory activity and can be used for the treatment of skin disorders, such as acne. 2-Phenylquinoline-4-carbohydrazide has been shown to induce apoptosis in human dermal fibroblast cells. This drug has been shown to have anticancer activity in vitro and in vivo. The anticancer activity of this drug may be due to its ability to inhibit cancer cell proliferation by binding to DNA gyrase and topoisomerase, which are enzymes that maintain the integrity of bacterial DNA.</p>

<p>5-Hydroxyisoquinoline is a quinoline derivative that is synthesized from aziridine. It has been shown to be a potent insulin sensitizing agent in mice with type 2 diabetes mellitus. 5-Hydroxyisoquinoline has been shown to inhibit the activity of purified enzymes preparations and show high selectivity for chloride channels, which are responsible for the transport of chloride ions across cell membranes. This inhibition leads to an influx of protons into the cell, which may lead to a change in the redox potential and changes in the molecular structure of the molecule. The reaction mechanism involves substitution at position 5 of the isoquinoline ring by hydroxy groups (OH).</p>

<p>5-Cyanoindole is a hydrophobic molecule that has been shown to have an inhibitory effect on the trifluoroacetic acid-induced fluorescence in the presence of chloride ions. It is also able to bind peptides and has been used as an antimicrobial peptide. 5-Cyanoindole can be synthesized electrochemically or by electrochemical impedance spectroscopy. The synthesis of 5-cyanoindole can be achieved through a Friedel-Crafts reaction, followed by a hydrolysis with hydrogen peroxide and then a reduction with sodium borohydride.<br>!-- END OF PRODUCT DESCRIPTION --&gt;</p>

<p>8-Hydroxy-7-methoxycoumarin is a fluorescent compound, which is a derivative of the coumarin family. This compound is typically sourced through synthetic organic chemistry processes involving the modification of natural coumarin compounds. Its mode of action involves the ability to absorb ultraviolet light and re-emit it as visible light, a characteristic feature of fluorescent molecules. This property makes it particularly useful in scientific research.</p>

<p>1,1'-Bicyclohexyl]-1-carboxylic acid (BCX) is a metal salt that is soluble in water. BCX has a quadratic structure and is a cyclohexanecarboxylic acid derivative. It can be made by the reaction between formic acid and chloride. BCX is used as an anti-diarrheal agent for the treatment of chronic diarrhea. It has been shown to have high entrapment efficiency and high efficiency when synthesized with dicyclomine. This technique uses formic acid as the solvent, which reacts with chloride to produce BCX.</p>

<p>4-Fluoroisoquinoline is a synthetic compound that can be produced by the reduction of an acetonitrile-chlorinated isoquinoline compound. It is also possible to produce 4-fluoroisoquinoline by the reaction of chlorinating agents with an aldehyde, followed by the addition of phosphorus oxychloride and fluorine. The reductive sulfonation of 4-fluoroisoquinoline can be achieved by reacting it with sulfur trioxide, which is in turn generated from phosphorous oxychloride and sulfur dioxide. This process produces the desired product in good yields.</p>

<p>2,9-Dibromo-1,10-phenanthroline is a molecule that has been shown to be an effective sensitizer for the photochemical conversion of chlorine dioxide to ozone. It has been used as a model compound in molecular orbital calculations and has been shown to enhance the yield of ozone by up to 3%. The emission spectrum of 2,9-dibromo-1,10-phenanthroline displays a peak at 362 nm, which lies in the ultraviolet region. The molecule is orthorhombic and crystallizes in space group P2/c with cell dimensions a = 17.8 Å and c = 18.7 Å.</p>

<p>1,3,9-Trimethylxanthine is a naturally occurring purine alkaloid that has been shown to have cytosolic calcium ion-antagonistic properties. It can also act as an antioxidant by donating electrons to free radicals and inhibiting lipid peroxidation. This compound is found in coffee beans and other sources of caffeine. It binds to the receptor for adenosine, which causes the antagonistic effects on intracellular calcium concentration. Trimethylxanthine can also be used to treat ventricular arrhythmias and increase locomotor activity in mammals. Trimethylxanthine has been shown to be effective in wastewater treatment as it removes organic pollutants from water by oxidizing them with hydrogen peroxide or chlorine gas.</p>

<p>4-Bromoindole is a model compound that serves as a building block for the synthesis of pharmaceutically important compounds. 4-Bromoindole has been shown to have high catalytic rates for the oxidative coupling of zirconium oxide. This compound can also be used in asymmetric synthesis because it is able to form both R and S enantiomers in moderate yield. The reaction mechanism is thought to involve a nucleophilic attack by bromide on the carbonyl group, followed by elimination of hydrogen bromide from this intermediate. 4-Bromoindole can be synthesized in three ways: (1) via an oxidative coupling reaction with ZrOCl2 and H2O2; (2) via an oxidative coupling reaction with ZrOCl2 and HBr; or (3) by reacting 4-bromoaniline with CuSO4 and Mn(NO3)2.</p>

<p>5,6-Difluoroindole is a chemical compound that has been studied in biological and chemical research. It is an analog of the neurotransmitter serotonin, which binds to the 5-HT2C receptor and activates phospholipase C (PLC) to produce inositol triphosphate (IP3). This compound may be useful for the treatment of neurodegenerative diseases such as Alzheimer's disease. 5,6-Difluoroindole has been shown to block the activity of acetylcholinesterase (AChE), which is an enzyme that breaks down acetylcholine. This leads to an increase in acetylcholine levels and a decrease in AChE activity. The reaction mechanism for this process is not known.</p>

<p>Indole-3-glyoxylamide is a synthetic compound that was originally developed as a potential anti-cancer drug. It has been shown to inhibit glycogen synthase kinase 3 (GSK-3) and thereby reduce the production of proinflammatory cytokines in bowel disease. Indole-3-glyoxylamide also inhibits inflammatory bowel disease by inhibiting secretory phospholipase A2, which prevents the release of arachidonic acid from phospholipids. This synthesis is required for the production of prostaglandins and leukotrienes, which are involved in the inflammatory process. The compound has been shown to have immunomodulatory effects in chronic bronchitis, with an inhibitory effect on neutrophil chemotaxis, macrophage activity, and cytokine production. Indole-3-glyoxylamide has also been shown to be effective against cancer cells in vitro and in vivo animal models. It is metabolized through</p>

<p>Angiotensin-converting enzyme inhibitor; anti-hypertensive</p>

<p>Please enquire for more information about Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cilostazol is a drug that binds to ATP-binding cassette (ABC) transporters, which are proteins that transport molecules across membranes. It decreases the production of cyclic nucleotides and phosphodiesterase, which are important in the regulation of blood vessel tone. Cilostazol has been shown to be effective in treating heart failure and atherosclerosis. Cilostazol also inhibits cyclase activity, an enzyme involved in the synthesis of cyclic nucleotides, which leads to vasodilation by increasing the concentration of cAMP. The drug is available in both immediate-release and controlled-release preparations. Cilostazol can have serious side effects such as congestive heart failure or stroke if it is taken with other drugs that inhibit platelet aggregation such as aspirin or warfarin.</p>

<p>3-(3-Piperidinopropoxy)-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazole is a compound that functions as an actuator. It can be used to implement force, such as controlling a change in the position of a control or actuation, and it can also be used to shift control. 3-(3-Piperidinopropoxy)-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazole is an actuation method that can be controlled by implementing force.</p>

<p>5,6-Dichloroindole is a chemical compound that contains a functional group with acidic properties. The compound has been shown to inhibit the activity of bafilomycin A1, which is an inhibitor of vacuolar ATPase. This inhibition leads to an increase in intracellular phosphate levels and an accumulation of lysosomal membrane proteins. 5,6-Dichloroindole has also been found to inhibit bone resorption in gramine-fed rats. It also has anti-inflammatory effects and inhibits the growth of zoobotryon pinnatum cells and algal cells. 5,6-Dichloroindole can be used as a molecular descriptor for predicting the presence or absence of bryozoan species in a sample.</p>

<p>1-Acetyl-1,2,3,4-tetrahydroquinolin-7-amine hydrochloride is a versatile building block that can be used in the synthesis of complex compounds with high quality and as a speciality chemical. This compound is useful as a reagent and reaction component in organic synthesis. It has been shown to be useful in the synthesis of new scaffolds for drug discovery.</p>

<p>6-Methyl-1H-indole-2,3-dione is a synthetic molecule that has an amide orientation. The molecule is a crystalline solid and can be found in the form of a white powder. This product also contains impurities such as amino acids, transport molecules, and formic acid. 6-Methyl-1H-indole-2,3-dione is soluble in solvents like formic acid and water. It has been shown to have transport properties for electrons and aldehydes.</p>

<p>5-Amino-1H-imidazole-4-carboxamide is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH). This enzyme converts inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) and is essential for the synthesis of purines. By inhibiting IMPDH, 5-amino-1H-imidazole-4-carboxamide prevents the formation of XMP, which leads to the depletion of purines, thereby inhibiting DNA synthesis. In addition to its role as an anti-inflammatory agent, this drug has been shown to reduce disease activity in bowel disease patients by reducing nitrate reductase activity. The molecule has also been shown to inhibit protein kinases such as PKC and MAPK/ERK kinases.</p>

<p>4-Chloro-8-methoxy-2-methylquinoline is a compound that has been found in nature. It is a diversity of nonreciprocal nucleic acid sequences and has been shown to be polymorphic. This nucleotide can cause stenosis in the coronary heart, which may lead to heart disease. 4-Chloro-8-methoxy-2-methylquinoline also inhibits the growth of Plasmodium falciparum and Plasmodium vivax. The drug's mechanism of action is not yet known, but it may have evolved from other compounds with a similar molecular structure.</p>

<p>Fluorescent dye used in diagnostic culture media</p>

<p>6-Methyl-1H-indole-3-carbaldehyde is a synthetic chemical that has been used as a reagent in the form of its sodium salt. It is an acetylating agent and can be used for formylation reactions. 6-Methyl-1H-indole-3-carbaldehyde has shown strong antifungal activity against phytopathogenic fungi such as Fusarium, Rhizoctonia, and Phytophthora. This chemical also has a triazine group, which can be used to enhance the herbicidal properties of certain compounds.</p>

<p>H-Imidazoleacetic acid is a synthetic compound that can be used to produce other compounds. It is soluble in water and has a hydrophilic interaction with calcium carbonate. H-Imidazoleacetic acid may be recycled, as it is easily synthesized from ethyl bromoacetate by reaction with hydrochloric acid. This substance has shown anticancer activity and may be used to treat blood pressure. The chromatographic method for H-Imidazoleacetic acid involves the use of extracellular medium to remove the organic solvent, followed by reversed phase chromatography on an ion exchange column. H-Imidazoleacetic acid is soluble in water and has a hydrophilic interaction with calcium carbonate. It may be recycled, as it is easily synthesized from ethyl bromoacetate by reaction with hydrochloric acid. This substance has shown anticancer activity and may be used to treat blood pressure. The</p>

<p>Indole-5-carboxylic acid is a chemical species that contains a heterocyclic ring with five atoms, one of which is a carboxyl group. It is an intermediate in the biosynthesis of tryptophan and histidine in the body. Indole-5-carboxylic acid has been used as a ligand to immobilize copper, nickel, palladium, and platinum on conductive supports. It has also been used for the structural analysis of dopamine by hybridization experiments and for the detection of mismatched hydrogen bonding interactions. This compound can be detected using FT-IR spectroscopy or electrochemical impedance spectroscopy.</p>

<p>8-Methoxypsoralen is a furocoumarin compound, which is derived from natural plant sources such as the seeds of the Ammi majus plant. Its primary mode of action involves intercalation into DNA strands and the formation of covalent bonds with pyrimidine bases upon exposure to ultraviolet A (UVA) light. This interaction results in the inhibition of DNA synthesis and cell proliferation.</p>

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<p>Quinolin-4-ylboronic acid is a heterocyclic compound with two nitrogen atoms that are attached to the ring by means of carbonyl groups. This compound is a precursor in the synthesis of the drug dorsomorphin, which is used for pain relief. It also has an important role in pharmacokinetics because it can be used as a marker for estimating blood levels of other drugs. Quinolin-4-ylboronic acid yields an active form, quinolin-4-yl boronic acid, when reacted with piperazine in basic conditions. The drug ldn-193189 is a derivative of this active form and has been evaluated as a potential drug for treating osteoporosis and cancer.</p>

<p>Methyl quinuclidine-3-carboxylate hydrochloride is a versatile building block that can be used to synthesize a variety of compounds. It is an intermediate in the production of high quality research chemicals and reagents. This compound has been shown to be useful as a scaffold for reactions that produce complex compounds with interesting biological activity. Methyl quinuclidine-3-carboxylate hydrochloride is a fine chemical that can be used as a reaction component or for other purposes.</p>

<p>1-Benzyl-1H-indole-2-carboxylic acid is a molecule that binds to chemokine receptors and has been used in screening assays as a chemical probe of chemokine receptor binding. It has been shown to be an antagonist of the CXCR3 receptor, with high affinity and selectivity. 1-Benzyl-1H-indole-2-carboxylic acid is also an antagonist of the CCR5 receptor, with low affinity. This compound was discovered by screening for novel antagonists of chemokines.</p>

<p>Indoline-2-carboxylic acid is a photophysical molecule with an absorption maximum at 518 nm. It has been shown to inhibit the activity of enzymes such as cyclooxygenase, lipoxygenase, and monoamine oxidases. This compound has been found to be effective in the treatment of cancer cells. Indoline-2-carboxylic acid is also used in pharmaceutical preparations, where it binds to enantiomers of other molecules and inhibits their biological activity. Indoline-2-carboxylic acid reacts with hydrochloric acid to form allyl carbonate and amide.</p>

<p>4-Hydroxy-2-methylindole is an organic compound that belongs to the class of metal salts. It can be obtained as a white solid by reacting indole with alkali metal hydroxide or alkali metal carbonate in the presence of water at high temperatures. The reaction yields 4-hydroxy-2-methylindole and hydrogen chloride gas, which are removed by distillation. 4-Hydroxy-2-methylindole is used in the production of epichlorohydrin, which is a raw material for polyurethane resins and olefins.</p>

<p>Imperatorin is a furanocoumarin compound, which is a natural product primarily isolated from plants in the Apiaceae family, such as Angelica dahurica and Citrus species. This compound is characterized by its unique chemical structure that includes a furan ring fused to a coumarin backbone. Imperatorin exerts its biological activities through multiple modes of action, including the modulation of enzymatic activity, interference with cellular signaling pathways, and binding to specific biological targets.</p>

<p>Esculetin dibenzyl ether is a chemical compound, which is a derivative of esculetin, a natural coumarin obtained chiefly from plant sources such as the bark of horse chestnut and other similar species. The source of esculetin dibenzyl ether is typically synthesized from natural precursors through chemical modifications, allowing for the exploration of its structural analogs.</p>

<p>Fraxin is a naturally occurring anticoagulant, which is derived from the bark of certain species of the Fraxinus tree. It functions by inhibiting thrombin and other key enzymes in the coagulation cascade, thus preventing the formation of blood clots. This mode of action makes it particularly valuable in research settings focused on cardiovascular diseases, as well as in the development of therapeutic agents targeting coagulopathies.</p>

<p>3-Methylphenanthrene is a compound that inhibits the reductase activity of aromatic hydrocarbons. 3-Methylphenanthrene has been shown to inhibit both bacterial and mammalian reductases, with interactive effects on the enzyme's substrate molecule. It also shows an inhibitory effect on axonal growth, which may be due to its ability to reduce fatty acid uptake, as well as its ability to interact with the aromatic hydrocarbon uptake system. 3-Methylphenanthrene is easily detected by spectrometry analyses and can be used as a substrate molecule for bacterial enzymes.</p>

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<p>4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.</p>

<p>5,7-Dinitroindole-2-carboxylic acid is a versatile building block that has been used as a reagent in organic synthesis. It has also been shown to be an intermediate in the preparation of 5,7-dichloroindole and other complex compounds. This compound is a reaction component for the synthesis of many useful compounds, including research chemicals and speciality chemicals. 5,7-Dinitroindole-2-carboxylic acid is soluble in most solvents and can be purified by recrystallization or chromatography. The purity can be determined by elemental analysis or nuclear magnetic resonance spectroscopy.</p>

<p>5-Bromoisatoic anhydride is a potential anticancer agent that contains nitrogen atoms. It inhibits the growth of cancer cells by binding to the enzyme acetylcholine, which is involved in the production of growth factors. The compound also inhibits the production of malonic acid, which is a metabolic disorder. 5-Bromoisatoic anhydride forms stable complexes with malonic acid and does not cause any adverse effects on normal cells.</p>

<p>Methyl indole-3-acetate is a phytochemical that inhibits the growth of cells. It has been shown to induce apoptosis in cancer cells, and also to inhibit carcinogenesis. Methyl indole-3-acetate is found at higher concentrations in the target tissue, such as the prostate gland, than in other tissues. This compound has been shown to inhibit lipid peroxidation in vitro and may be useful for the prevention of oxidative damage as well as for its antitumor activity. The effects of methyl indole-3-acetate on cell growth are related to its ability to bind with amines and uroquinase enzymes. Methyl indole-3-acetate has been shown to have anti-cancer properties in various model systems, including microbial metabolism studies.</p>

<p>6-Hydroxy-4-methylcoumarin is a chemical compound that serves as a lactone derivative. It is commonly derived from synthetic sources through various organic reactions involving resorcinol and ethyl acetoacetate. The compound functions primarily through its ability to absorb ultraviolet light and fluoresce, making it highly valuable in spectroscopic analyses.</p>

<p>7-Methoxy-4-methylcoumarin is a synthetic organic compound, which is a derivative of coumarins—a class of compounds widely found in plants. This compound is primarily synthesized through organic chemical reactions rather than extracted directly from natural sources. Its mode of action involves exhibiting fluorescence, which makes it a valuable probe in various scientific studies.</p>

<p>1,10-Phenanthroline-2-carbaldehyde is a phenylhydrazone compound that has been shown to have anticancer activity. It is also a supramolecular complex, which means it can form hydrogen bonds and coordinate bonds with other molecules. The anticancer activity of 1,10-phenanthroline-2-carbaldehyde may be due to its ability to inhibit the growth of prostate carcinoma cells. This compound also inhibits the growth of human cervical carcinoma cells by binding to their DNA and inhibiting the synthesis of RNA and protein. 1,10-Phenanthroline-2-carbaldehyde is being studied for its potential as an inhibitor of tumor angiogenesis.<br>1,10-Phenanthroline-2-carbaldehyde has been shown to have antiplatelet aggregation effects in platelets from healthy humans as well as those with type 2 diabetes mellitus or chronic kidney disease.</p>

<p>Please enquire for more information about 3,4-diaza-5-(tert-butyl)-2-hydroxy-3-((4-methylphenyl)sulfonyl)tricyclo[6.4.0.0&lt;2,6&gt;]dodeca-1(8),4,9,11-tetraen-7-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Isoquinoline-4-carbaldehyde is an aldehyde chemical that has been synthesized in the laboratory. It is a chiral molecule with one asymmetric carbonyl group. Isoquinoline-4-carbaldehyde is a potential precursor to naphthyridine, which can be used as a building block for the synthesis of natural products. Isoquinoline-4-carbaldehyde has been shown to have phosphine properties, and it can be used as a ligand in transition metal complexes. The molecule has been shown to exist in two forms, which coexist in equilibrium and can undergo interconversion.</p>

<p>4,4'-Dichloro-2,2'-bipyridine (4,4'-DDBP) is a polydentate ligand that has been shown to be highly cytotoxic against cancer cells. 4,4'-DDBP binds to amines in the cancer cell and uses its nucleophilic character to activate the amine by displacement of chloride ions. This leads to the production of an excited state that can be used for photodynamic therapy or as a fluorescence probe. This compound has also been shown to have operational kinetic properties in the inhibition of bilirubin oxidase.</p>

<p>4-Fluoro-1H-indole-3-carbaldehyde is a chemical compound that can be used as a reagent, reaction component, or building block in the synthesis of more complex compounds. This chemical is also known as CAS No. 23073-31-6 and has high quality and purity. 4-Fluoro-1H-indole-3-carbaldehyde is useful for research purposes and can be used as a speciality chemical or a fine chemical.</p>

<p>4-Oxo-1,4-dihydroquinoline-3-carboxylic acid is a synthetic compound that belongs to the class of quinoline derivatives. It has been shown to inhibit HIV infection in vitro by binding to the receptor CD4 on the surface of T cells. 4-Oxo-1,4-dihydroquinoline-3-carboxylic acid has also been shown to be cytotoxic against cancer cells and other human cell lines. Powders of 4-oxo-1,4-dihydroquinoline 3 carboxylic acid have been synthesized by reacting ethyl esters with diphenyl ether in the presence of radiation or ndimethylformamide. This compound was also used as a molecular model for designing new drugs.</p>

<p>Geiparvarin is a cytotoxic compound, which is a plant-derived chemical with notable bioactivity. It is sourced from the roots of the Daflon plant, known for various natural compounds with potential therapeutic effects. Geiparvarin acts by interfering with cellular processes, leading to apoptosis in malignant cells. This mode of action is particularly significant in the study and development of anticancer therapies.</p>

<p>L-5-Methyltetrahydrofolate calcium is also known as calcium levomefolate; N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt; and L-5-MTHF. L-5-Methyltetrahydrofolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.</p>

<p>7-Hydroxy-1,2,3,4-tetrahydroquinoline (7OH-THQ) is a fluorophore that can be used to detect the presence of cancer cells. It is a linker and labile and can be synthesized from the lactam 7-hydroxypyrazolo-[4,3-a]pyridin-5(6H)-one. The synthesis of 7OH-THQ is possible by reacting 4-(dimethylamino)benzenesulfonyl chloride with 2,2'-dithiolethane in the presence of sodium hydroxide. 7OH-THQ has been shown to be effective as an anticancer drug in vitro assays for colon and breast cancer cells. It also has fluorescence properties that are sensitive to acidic conditions and pH levels.</p>

<p>6-Fluoroindole-3-carboxaldehyde (6FLA) is a synthetic compound that inhibits biosynthesis of the phytoalexins salicylic acid and lignin in plants. It also inhibits the β-glucuronidase enzyme, which hydrolyzes the glucuronide conjugates of phenolic compounds and xenobiotics. 6FLA has been shown to cause mild liver damage in rats, but its effects on humans are unknown. 6FLA may be used as a detectable substance for assays.</p>

<p>1,10-Phenanthroline·HCl·H2O is a chemical compound that has been used for the preparation of samples for spectroscopic analysis. The compound is chemically stable and resistant to hydrolysis, making it suitable for long-term storage. 1,10-Phenanthroline·HCl·H2O has an inhibitory effect on bitter taste receptors in the mouth. It also has a hydroxyl group and a carbonyl group, which can react with acid molecules to form hydrogen ions and water. 1,10-Phenanthroline·HCl·H2O belongs to the class of metal ion sequestrants and can be used to remove aluminium from solutions. The molecular formula of this compound is C14H12N2O4Cl2. The structural formula is shown below:<br><br>[[image:1,10-phenanthroline-hcl-h2o.png]]</p>

<p>7-Ethylindole-3-glyoxylic acid ethyl ester is a versatile building block that can be used in the synthesis of complex compounds. It is a useful intermediate in the synthesis of pharmaceuticals, which can also be used as a reagent and speciality chemical. The compound has been shown to have high quality and is a useful scaffold for the synthesis of new compounds.</p>

<p>5-Methoxyindole is a chemical compound that is soluble in water. It has been shown to inhibit tumor growth and induce apoptosis, as well as inhibit the expression of glycogen synthase kinase-3. The structure of 5-methoxyindole was determined by NMR spectroscopy and FT-IR spectroscopy. The compound has been observed to exhibit fluorescence properties at a wavelength of 490 nm when it is excited with UV light. A copper complex of 5-methoxyindole was studied using molecular modeling and FT-IR spectroscopy, which revealed that it can undergo nucleophilic attack by hydrogen bond formation or an acid/base reaction to form a new hydrogen bond. This study also found that 5-methoxyindole is able to form hydrogen bonds with its neighboring molecules, which may contribute to its high solubility in water.</p>

<p>2-Aminoacridone is a fluorescent dye.  The applications of 2-Aminoacridone are extensive in biochemical and analytical research. It is commonly employed in glycoprotein and glycoconjugate studies, leveraging its high sensitivity and specificity in detecting saccharide structures. Researchers utilize this dye in various assays, including high-performance liquid chromatography (HPLC) and electrophoresis, to analyze carbohydrate content and structure. Its role is critical in advancing our understanding of carbohydrate-related biological processes, such as cell signaling and disease pathogenesis, facilitating developments in both diagnostics and therapeutic strategies.</p>

<p>5,7-Dimethoxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from various plant species, most notably those belonging to the Apiaceae and Rutaceae families. This compound is characterized by the presence of methoxy groups at the 5 and 7 positions on the coumarin core structure. These structural features contribute to its biological activity by influencing its interaction with various biomolecular targets.</p>