Composés polycycliques

Stability Air Sensitive
Applications Alpha-Pyridoin (cas# 1141-06-6) is a useful research chemical.

Applications 2,2'-Bipyridine-4,4'-dicarboxylic acid

Applications 7-Deazapurine (cas# 18549-65-0) is a compound useful in organic synthesis.

Applications (2R,3aR,7aR)-Octahydroindole-2-carboxylic Acid Hydrochloride is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Vincent, M., et al.: Drug Design Disc., 9, 11 (1992), Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)

Applications 6-Bromo-1h-Pyrido[2,3-B][1,4]Oxazin-2(3h)-One (cas# 1245708-13-7) is a useful research chemical.

Applications 2,2'-(2-Hydroxypropane-1,3-diyl)bis(1H-isoindole-1,3(2H)-dione) is a reagent used for the preparation of functionalized tripodal ligands and their metal complexes for imaging applications.
References Dunn, T.J., et al.: PCT Int. Appl., 1995:494561 (1995)

Applications 4,4-difluoro-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 1443981-83-6) is a useful research chemical.

Applications 2-​Quinolinecarboxylic acid can be found in the studying of ligands for the purpose of copper-catalyzed Ullmann reactions with aryl ethers and aryl iodides.

Stability Store under Argon
Applications 3,6-Thioxanthenediamine-10,10-dioxide (cas# 10215-25-5) is a compound useful in organic synthesis.

Stability Light Sensitive
Applications Reacts with aldehydes to produce highly fluorescent imidazole derivatives. A fluorometric labeling reagent.

Applications Bicyclo[4.1.0]Heptane-7-Carboxylic Acid (cas# 41894-76-2) is a useful reagent for the heteroatom-​directed C-​H borylation of cyclopropanes and cyclobutanes.
References Murakami, R., et al.: Chem. Eur. J., 20, 13127 (2014)

Applications tert-Butyl 1,6-Diazaspiro[3.4]octane-1-carboxylate is a reactant in the preparation of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors.
References Sippy, K.B., et. al.: Bioorg. Med. Chem. Lett., 19, 1682 (2009)

Applications 3-(quinolin-2-yl)propanoic acid (cas# 39111-94-9) is a useful research chemical for biological study. In particular it has been used in identifying structure-activity relationship of HDAC6 zinc-finger ubiquitin binding domain inhibitors.
References Ferreira, F., et al.: J. Med. Chem, 61, 4517 (2018)

Applications 1,10-Phenanthroline-d8 (CAS# 90412-47-8) is a useful isotopically labeled research compound.

Applications Ethyl 6-Cyano-1H-indole-2-carboxylate is a chemical reagent used in the synthesis of benzofuran inhibitors for mitogen-activated protein kinase phosphatase-1. Applications towards diabetes, obesity and insulin-resistant metabolic disorders. Also a reagent in the preparation of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists used as ati-thrombotic agents.
References Lazo, J. et al.: Bioorg. Med. Chem., 14, 5643 (2006); Ono, S. et al.: Chem. Pharm. Bull.,

Applications 1-Chloro-5-isoquinolinesulfonic Acid (cas# 105627-80-3) is a compound useful in organic synthesis.

Applications 4,7-Dimethylquinolin-2(1H)-one is a reagent in the preparartion of citralidene hydrazido quinolinones which has antibacterial activity.
References Piste, P. B., et al.: J. Chem. Biol. Phy. Sci., 3, 1746 (2013);

Applications 3-(4-Aminobutyl)-1H-indole-5-carbonitrile could be a useful reagent for preparing CNS agents.
References Boettcher, H., et al.: Ger. Offen. (1992), DE 4101686 A1

Applications 1,3-Dihydro-N-nitro-1,3-dioxo-2H-isoindole-2-carboximidothioic acid Methyl Ester is an intermediate in the synthesis of Dinoteturan (D482100), a neonicotinoid insecticide.
References Wakita, T., et al.: J. Pesticide. Sci., 29, 348 (2004);

Applications 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid 1,1-Dimethylethyl Ester (cas# 123387-51-9) is a compound useful in organic synthesis.

Applications 2,4-Dimethylquinoline, �� 95.0% (cas# 1198-37-4) is a useful research chemical.

Applications 1,2,3,4,5,6,7,8-OCTAHYDROPHENANTHRENE (cas# 5325-97-3) is a useful research chemical.

Applications 2-(quinolin-4-yl)ethan-1-amine (cas# 860720-12-3) is a useful research chemical.

Applications 1,2,3,4-Tetrahydroisoquinoline-6,7-diol hydrobromide (cas# 52768-23-7) is a useful research chemical.

Applications Methyl indoline-5-carboxylate

Applications (2R,3aS,7aS)-Octahydroindole-2-carboxylic Acid Hydrochloride is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Vincent, M., et al.: Drug Design Disc., 9, 11 (1992), Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)

Applications 6-Hydroxyindole-2-carboxylic acid (cas# 40047-23-2) is a useful research chemical.

Applications 3,5-Diphenylpyrazole (cas# 1145-01-3) is a useful research chemical.

Applications 1-Benzylindole-5-boronic Acid Pinacol Ester acts as a reagent in the synthesis of 3,3-difluoro-2-oxindoles via electrophilic fluorination of indoles using N-fluorobenzenesulfonimide. Preparation of triazolopyridine compounds as JAK kinase inhibitors useful in the treatment of neurodegenerative and inflammatory diseases.
References : Lim, Y., et al.: Org. Lett., 14, 5676; Menet, C., et al.: PCT Int. Appl. (2010), WO 2010010190 A1 20100128.

Applications 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE (cas# 5439-14-5) is a useful research chemical.

Applications Oxyquinoline Sulfate is used as a food preservative.
References Gendy, A. et al.: Aud. J. Basic. App. Sci., 6, 260 (2012); Abou El-Ghait, E. et al.: Res. J. Agri. Biol. Sci., 8, 261 (2012);

Applications Quinoline-3-sulfonyl Chloride (cas# 159182-40-8) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 7-Phenyl-7H-purine (cas# 18346-05-9) is a compound useful in organic synthesis.

Applications 6-hydroxyquinoline-2-carboxylic acid (cas# 75434-18-3) is a useful research chemical.

Applications 1-benzyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas# 155413-72-2) is a useful research chemical.

Applications 3-Cyanoindole (cas# 5457-28-3) is a compound useful in organic synthesis.

Applications 1,2,3,4-Tetrahydroquinolin-3-amine (cas# 40615-02-9) is a useful research chemical.

Applications 7-BROMOMETHYLQUINOLINE HYDROBROMIDE (cas# 188874-61-5) is a useful research chemical.

Applications 9-Oxo-9H-thioxanthene-2-carboxylic acid (cas# 25095-94-7) is a useful research chemical.

Applications 4-Fluoro-1H-indazole

Applications 4-Chloro-7-(trifluoromethyl)quinoline is a reagent in the preparation of piperazinylquinolines as breast cancer inhibitors.
References Solomon, V., et al.: Bioorg. Med. Chem., 18, 1563 (2010);

Applications 5,7-Dichloro-3,4-dihydro-2H-isoquinolin-1-one (cas# 885273-81-4) is a useful research chemical.

Applications 8-aza-9-boratricyclo[8.4.0.0,2,7]tetradeca-1(14),2,4,6,10,12-hexaen-9-ol (cas# 17012-25-8) is a useful research chemical.

Stability Hygroscopic
Applications 2-(1,3-Dioxo-3,4-dihydroisoquinolin-2(1H)-yl)acetic Acid (cas# 52208-61-4) is a useful research chemical.

Applications 4-Hydroxymethylbicyclo[2.2.2]octane-1-carboxylic Acid Isopropylamide is a useful synthetic intermediate.

Applications 6-Chloro-3,4-dihydro-4-hydroxy-3-(phenylsulfonyl)-4-(trifluoromethyl)-2(1H)-quinolinone is an intermediate in the synthesis of novel quinolinones as HIV-1 reverse transcriptase inhibitors.
References Patel, M., et al.: Bioorg. Med. Chem. Lett., 11, 1943 (2001);

Applications 6-Propylamino-7-deazapurine (cas# 60972-21-6) is a compound useful in organic synthesis.

Applications Methyl 4-formylbicyclo[2.2.2]octane-1-carboxylate (cas# 94994-25-9) is a useful research chemical.

Applications 2’,3’,5’-Tri-O-benzoyl Xanthine-13C5 is an intermediate used in the synthesis of Xanthosine-13C5 (X742102), which is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure.
References Magasanik, B, et al.: J. Bio. Chem., 206, 83 (1954);

Applications 4-Ethyl-2(1H)-quinolinone has been use as a reactant in the preparation of 6-bisalkylamino-2-quinolinones as selective androgen receptor modulators.
References Van Oeveren, A., et. al.: Bioorg. Med. Chem. Lett., 17, 1527 (2007)

Applications 2-azaspiro[4.5]decane-1,3-dione (cas# 1197-80-4) is related to gabapentin (G117250).

Applications (2R,3aR,7aR)-rel-OctahydroIndole-2-carboxylic Acid is a reactant in the preparation of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Blankley, C.J., et. al.: J. Med. Chem., 30, 992 (1987)

Applications 4,7-difluoro-1H-indole-2-carboxylic acid (cas# 247564-67-6) is a useful research chemical.

Applications 2,3,3-Trimethylindolenine-5-sulfonic Acid, Potassium Salt (cas# 184351-56-2) is a compound useful in organic synthesis.

Applications 6-Hydroxyquinoline-(1H)-2-one (cas# 19315-93-6) is a compound useful in organic synthesis.

Applications 2-(prop-2-yn-1-yl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 410538-30-6) is a useful research chemical.

Applications 1-(4-Chlorobutyl)-7-hydroxyquinolin-2(1H)-one is a useful research chemical.

Applications 3-Hydroxyquinoline-d6 is labelled 3-Hydroxyquinoline (H953140) which is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.
References Riego, E. et al.: Tetrahedron, 61, 1407 (2005); Kanou, M. et al.: Fund. Clin. Pharmacol., 16, 513 (2002)