Composés polycycliques

<p>7-Methoxy-8-hydroxy-4-phenylcoumarin is a coumarin derivative, a type of organic compound characterized by a benzopyrone structure. This compound is typically derived from natural plant sources or synthesized in laboratory settings. Its structural features, such as the methoxy and hydroxy groups, are integral to its potential biological activity.</p>

<p>Please enquire for more information about 6-Benzyloxy-5-methoxyindole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4,6-Dichloroisatin is a pro-apoptotic compound that is synthesized from amino acids. It has been shown to have anticancer activity in human liver cancer cells, which may be due to its ability to induce apoptosis. 4,6-Dichloroisatin has also been shown to inhibit the production of electron transport chain proteins in the mitochondria by binding to their regulatory sites and inhibiting their phosphorylation. This inhibition of electron transport chain proteins leads to an accumulation of electrons that can react with molecular oxygen and produce reactive oxygen species (ROS). ROS are known for their ability to cause DNA damage and cell death through oxidative stress.</p>

<p>2-Hydroxy-4-methylquinoline is an organic compound that has a chelate ring. It is soluble in deionized water and reacts with metal ions to form a fluorescent product. The molecule also has antibacterial activity, which may be due to its ability to inhibit the growth of bacteria by acting as a metal ion chelator. 2-Hydroxy-4-methylquinoline can react with halides and ammonium persulfate to form isomeric products, such as 4,5-dihydroxyquinoline, which have been shown to have antimicrobial properties. 2-Hydroxy-4-methylquinoline can also react with phosphorus oxychloride and alkylating agents such as chloroethane or chloroform to form substituted derivatives.</p>

<p>7-Ethoxy-4-methylcoumarin is a fluorescent probe, which is a synthetic compound commonly sourced from organic chemical synthesis. With its distinct chromophore, this compound becomes highly fluorescent upon enzymatic cleavage, offering a reliable mechanism for the detection of specific enzymatic activities. The mode of action involves the enzymatic cleavage of the ethoxy group, leading to the release of 4-methylumbelliferone, a fluorescent product. This conversion provides a measurable signal that correlates with enzyme activity, making it an invaluable tool in studying enzyme kinetics.</p>

<p>Arnottinin is a bioactive compound, which is derived from natural plant sources. It functions primarily through modulation of specific cellular pathways, targeting key receptors that regulate physiological responses. This compound exhibits its mode of action by influencing signal transduction pathways, effectively altering cellular activities at the molecular level.</p>

<p>Please enquire for more information about tert-Butyl 4-chloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Hydroxyquinoline-4-carboxylic acid is a carboxylate that is structurally classified as a multidrug. It has been shown to inhibit bacterial efflux pumps and target enzymes, such as cancer cells and multidrug resistant bacteria. 2-Hydroxyquinoline-4-carboxylic acid also has potent antibacterial activity against Streptococcus faecalis, an opportunistic pathogen that causes infections in the urinary tract and on skin wounds. The fluorescence properties of this compound can be used for fluorescent labeling of biomolecules or for sensing applications.</p>

<p>Please enquire for more information about Methyl 4-(benzyloxy)-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine (8MMX) is an intracellular calcium ion chelator that inhibits enzyme activity in the cyclic nucleotide phosphodiesterase enzyme family. 8MMX has been shown to be a potent inhibitor of both cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase isoenzymes. 8MMX has been shown to inhibit bladder contractility and improve bladder function in animal models. It also reduces the incidence of papillary muscle rupture, which can lead to heart failure, and improves ventricular function by increasing the rate of relaxation of the left ventricle.<br>8MMX is a potential treatment for pulmonary hypertension, which is caused by increased concentrations of intracellular calcium ions.</p>

<p>Please enquire for more information about 1-(2-Methoxyethyl)-1H-indole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (3R)-1-Azabicyclo[2.2.2]oct-3-yl N-[2-(2-benzoylphenyl)ethyl]carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 6-Bromo-4-methoxy-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Bromo-3-methyl-1H-indazole is an organic compound that is synthesized from lithium diisopropylamide and lithium. 5-Bromo-3-methyl-1H-indazole is a white solid with a melting point of 151°C. It reacts with anhydrous hydrogen bromide to form 5,5'-dibromoindazole. The molecular weight of this compound is 202.2 g/mol.</p>

<p>Timapiprant is an amide that acts as a selective inhibitor of the prostanoid receptor CRTH2, which is involved in regulating the inflammatory response. Timapiprant inhibits skin eosinophilia, which is associated with inflammatory skin diseases such as atopic dermatitis and psoriasis. It has been shown to be safe in clinical trials and has a good safety profile. The drug's mechanism of action may be due to its ability to inhibit the production of IL-4 and IL-13 by Th2 cells and its ability to inhibit lung function. Timapiprant has shown efficacy in treating allergic rhinitis, asthma, chronic obstructive pulmonary disease, erythema multiforme, pyoderma gangrenosum, and other types of inflammatory skin diseases.</p>

<p>Ethyl 1,2-dimethyl-5-hydroxyindole-3-carboxylate (EDMC) is an implantable drug that is used to treat hypertension. It is a diuretic that can be taken orally or injected. EDMC works by reducing the amount of urea nitrogen in the blood and increasing the amount of chlorine atom in the urine. This leads to an increase in active substances such as malonic acid and a decrease in arthropoda. EDMC has been shown to have antihypertensive activity due to its ability to lower diastolic and systolic pressure. The molecule also contains hydroxyl group and aldehyde groups that are analyzed by analytical chemistry.</p>

<p>Please enquire for more information about Quinoline-6-sulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Selinidin is a phytochemical compound, which is derived from the natural source of the Brunsvigia bosmaniae plant. As a bioactive constituent of this plant, it is characterized by its unique structure and chemical properties, enabling it to interact with a variety of cellular targets, primarily through modulation of inflammatory pathways. The mode of action of Selinidin involves the inhibition of pro-inflammatory cytokines and mediators, thereby reducing inflammation and oxidative stress at the cellular level.</p>

<p>Isobergapten is a naturally occurring furanocoumarin, which is primarily derived from plants in the Apiaceae family, such as celery and parsley. The compound is structurally characterized by its fused furan and coumarin rings. It exerts its effects through its ability to interact with cellular enzymes and DNA, often influencing photodynamic processes. This interaction can result in modifications to DNA replication and transcription, making it a compound of interest in photochemotherapy and photobiology.</p>