Composés polycycliques

<p>Suberosin epoxide is a naturally occurring compound, classified as a type of sesquiterpene lactone, which is extracted from certain plant species, particularly those belonging to the Rutaceae family. This compound is of significant interest due to its biologically active properties. Its mode of action typically involves the modulation of enzymatic pathways within biological systems, often interacting with cellular proteins and potentially affecting signal transduction processes.</p>

<p>7-Amino-4-(methoxymethyl)coumarin is a fluorogenic compound, which is synthesized chemically for bioanalytical applications. This compound serves as a substrate in enzyme assays and is particularly valuable in studying enzymatic activity due to its fluorescent properties.</p>

<p>Please enquire for more information about 1-Methylindole-3-acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 6-Benzyloxy-5-methoxyindole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Indole-7-methanol is a flavin cofactor that catalyses the formylation of indole-7-carboxylic acid. Indole-7-methanol can be synthesized by the conversion of indole-7-carboxaldehyde with formaldehyde and ammonium acetate. The macrocyclic, isomeric, and formylated forms of indole-7-methanol have been shown to have utilisation activity in the synthesis of various compounds. These reactions are catalyzed by flavins such as FAD or FMN. Mutant, unsymmetrical derivatives of indole-7-methanol are also known to undergo these types of reactions. The most common derivative is indirubin, which has been shown to inhibit DNA polymerase III and IV in vitro.</p>

<p>7-Ethoxy-4-methylcoumarin is a fluorescent probe, which is a synthetic compound commonly sourced from organic chemical synthesis. With its distinct chromophore, this compound becomes highly fluorescent upon enzymatic cleavage, offering a reliable mechanism for the detection of specific enzymatic activities. The mode of action involves the enzymatic cleavage of the ethoxy group, leading to the release of 4-methylumbelliferone, a fluorescent product. This conversion provides a measurable signal that correlates with enzyme activity, making it an invaluable tool in studying enzyme kinetics.</p>

<p>Please enquire for more information about tert-Butyl 4-chloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Moluccanin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 4-(benzyloxy)-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine (8MMX) is an intracellular calcium ion chelator that inhibits enzyme activity in the cyclic nucleotide phosphodiesterase enzyme family. 8MMX has been shown to be a potent inhibitor of both cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase isoenzymes. 8MMX has been shown to inhibit bladder contractility and improve bladder function in animal models. It also reduces the incidence of papillary muscle rupture, which can lead to heart failure, and improves ventricular function by increasing the rate of relaxation of the left ventricle.<br>8MMX is a potential treatment for pulmonary hypertension, which is caused by increased concentrations of intracellular calcium ions.</p>

<p>Please enquire for more information about tert-Butyl 4-hydroxy-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Iodo-1H-imidazole is an asymmetric molecule that is synthesized by a Suzuki coupling reaction between malonic acid and tautomers of 2-iodo-1H-imidazole. This molecule inhibits the activity of inhibitor molecules, such as nitrogen atoms, which are used in pesticide production. It also has pesticidal activity and can be used to treat cancer or autoimmune diseases. 2-Iodo-1H-imidazole is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer.</p>

<p>Please enquire for more information about 6-Bromo-4-methoxy-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Acetyl-5-hydroxymethyl-7-hydroxycoumarin is a synthetic coumarin derivative, which is a class of organic compounds often found in natural products. These compounds are derived from plant sources and are known for their significant biochemical effects and aromatic properties. The mode of action of 3-Acetyl-5-hydroxymethyl-7-hydroxycoumarin involves interactions at the molecular level, where it can exhibit various biological activities, such as antioxidant and antimicrobial effects. Due to the hydroxyl and acetyl functional groups present, it can participate in redox reactions and binding interactions, affecting biochemical pathways.</p>

<p>Ethyl 5-fluoroindole-2-carboxylate is a cytotoxic compound that belongs to the class of organic compounds called aryl rings. It has been shown to inhibit tumor growth in vitro and in vivo through the inhibition of protein synthesis. The molecular docking studies have shown that this compound binds to the enzyme SMMC-7721 cell, which is involved in DNA transcription and replication. It also inhibits activity of other enzymes, such as kinases and phosphatases, which are involved in cellular processes such as proliferation and differentiation. Ethyl 5-fluoroindole-2-carboxylate may be used for the treatment of blood cancer or monosugar diseases, such as diabetes mellitus or hyperlipidemia.</p>

<p>Please enquire for more information about Ethyl 3-{[(1E)-(dimethylamino)methylene]amino}-5-methoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Geranyloxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from plant species in the Rutaceae family. It is a bioactive compound known for its presence in various essential oils and its contribution to the properties of these plant extracts. The mode of action of 7-Geranyloxycoumarin involves interactions at the cellular level, including enzyme inhibition and modulation of signal transduction pathways, which can lead to diverse pharmacological effects.</p>

<p>Oxypeucedanin hydrate is a natural furanocoumarin compound, which is derived from various plant sources, such as citrus fruits and members of the Apiaceae family. As a secondary metabolite, it plays a role in plant defense mechanisms against herbivores and pathogens.</p>