Composés organosiliciés

<p>S19625 - Trimethylsilyl methacrylate inhibited MEHQ</p>

<p>DMS-T01 - Polydimethylsiloxanes, trimethylsiloxy terminated cSt 1.0</p>

<p>S21325 - Tris(trimethylsilyl)phosphate</p>

<p>S25332 - 4,4'-Bis(triethoxysilyl)biphenyl</p>

<p>S19430 - O-(2-Trimethylsilylethyl)hydroxylamine-hydrochloride</p>

<p>S12645 - n-Octyldimethylsilane</p>

<p>S25250 - S-(Octanoyl)mercaptopropyltriethoxysilane</p>

<p>S00019 - Acetoxyethyl trimethoxysilane</p>

<p>S02890 - 4-Bromo-N,N-bistrimethylsilylaniline</p>

<p>S03190 - 3-Butenyltrimethylsilane</p>

<p>S25058 - [(Bicycloheptenyl)ethyl]trimethoxysilane</p>

<p>S06375 - Diethyldiethoxysilane</p>

<p>S25175 - Hexaethoxydisilane</p>

<p>S19900 - 4-Trimethylsilyloxybenzaldehyde</p>

<p>S02110 - Bis(triethoxysilyl)ethylene</p>

<p>S02775 - Bis(trimethylsilylmethyl) sulphide</p>

<p>S12240 - n-Octadecylsilane</p>

<p>S00750 - 3-Aminopropyldimethylethoxysilane</p>

<p>S25287 - Tris(glycidoxypropyldimethylsiloxy)phenylsilane</p>

<p>Impurity Paclitaxel - In House Impurity<br>Applications Protected Baccatin III. Paclitaxel - In House Impurity.<br></p>

<p>Applications TETRAMETHYLAMMONIUM BOROHYDRIDE (cas# 16883-45-7) is a useful research chemical.<br></p>

<p>Applications Dibenzothiophene-2-boronic acid is a useful reagent for organic synthesis and other chemical processes.<br>References Duncton, M. A. J., et al.: Org. Lett., 10, 3259 (2008)<br></p>

<p>Applications trans-Campestanyl 3-(4-(tert-Butyldimethylsilyl)oxy)-ferulate is an intermediate used in the synthesis of trans-Campestanyl Ferulate (C155308), which is used for synthesis of trans-feruloyl-β-sitostanol.<br>References Condo, A., et al.: J. Agric. Food Chem., 49, 4961 (2001);<br></p>

<p>Applications 1,1,3,3-Tetramethyldisiloxane is an organosilane reducing agent and can be used in several reduction reactions including reductive formation of sulfides and reductive etherification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pesti, J., et al.: Org. Process Res. Dev., pages ahead of print (2016);<br></p>

<p>Applications Trimethylboroxin (50% Solution in THF) is used in a diverse array of areas, including as a polymerization additive. Trimethylboroxin is also used in the preparation of CBS catalysts for asymmetric reductions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gilmore, N., et al.: Tetrahedron Asy., 14, 2115 (2003); Najera, C., et al.: Adv. Synth. Catal., 346, 1798 (2004);<br></p>

<p>Applications 2-Hydroxyphenylboronic acid<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications It is used for synthesis of unsymmetrical biaryls via aromatic C-H borylation-cross-coupling sequence.<br>References Stephens, T. et al.: Org. Lett., 19, 3498 (2017);<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal (cas# 89922-82-7) is a compound useful in organic synthesis.<br></p>

<p>Applications tert-Butyl-(3-iodo-1,1-dimethyl-propoxy)-dimethyl-silane (cas# 105262-85-9) is used as a reagent in the preparation of Methyl Acetoacetate.<br>References Heslin, J. C., et al.: J. Chem. Soc. [Perkin 1]. 6, 1417 (1988)<br></p>

<p>Applications B-(9-Phenyl-9H-carbazol-3-yl)boronic Acid is used in the synthesis of alkyl-functionalized organic dyes.<br>References Lee, E. et al.: Bull. Kor. Chem. Soc., 33, 293 (2012);<br></p>

<p>Applications Tris(trimethylsilyl)guanine is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing.<br>References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)<br></p>

<p>Stability Moisture Sensitive<br>Applications Chloroborane Methyl Sulfide Complex is a reagent in the synthesis of 3,4-Dimethyl-5-pentyl-2-furanundecanoic Acid (D477535); a furan fatty acid known to exhibit radical-scavenging ability and having anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Grahl, N., et al.: Marine. Biol., 157, 1567 (2010); Spiteller, G., et al.: Lipids., 40, 75 (2005); Wakimoto, T., et al.: PNSA., 108, 17533 (2011)<br></p>

<p>Stability Hygroscopic<br>Applications Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Pfefferkorn, J., et al.: J. Med. Chem., 51, 31 (2008);<br></p>

<p>Applications Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate is used in synthesis of 1-Alkynyl(triphenyl)arsonium Tetrafluoroborates by onium transfer reaction of 1-Alkynyl(phenyl)iodonium Tetrafluoroborates with Triphenylarsine. Also, used in preparation of Furan- and Thiophene-substituted alkynes and alkynyl ketones by Copper Iodide-catalyzed coupling and carbonylation of Heterocyclic Boronic Acids with Alkynyliodonium salts.<br>References Nagaoka, T., et al.: Tetrah. Lett., 36, 261-4 (1995); Yu, Chan-Mo, et al.: Synlett, 2631-2634 (2005);<br></p>

<p>Applications 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor.<br>References Nuzzi, A., et al.: Eur. J. Med. Chem., 111, 138 (2016); Rogueiro-Ren, A., et al.: ACS Med. Chem. Lett., 7, 568 (2016);<br></p>

<p>Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.<br>References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)<br></p>

<p>Applications Bromotrimethylsilane is used as a reagent in the synthesis of α-carboxy nucleoside phosphonate analogs as HIV reverse transcriptase-targeting agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keane, S.J., et al.: J. Org. Chem., ahead of print (2014)<br></p>

<p>Stability Volatile<br>Applications Allyltrimethylsilane is used in the allylation of aldehydes, imines, allylic and benzylic alcohols, and chiral α-keto-amides that are derived from (S)-proline esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yadav, J.S., et al.: Tetrahedron Lett., 43, 3783 (2002); Aggarwal, V.K., et al.: Tetrahedron Lett., 37, 3745 (1996); Wang, D.K., et al.: J. Org. Chem., 64, 4233 (1999); Kaur, G., et al.: Tetrahedron Lett., 38, 2521 (1997); Soai, K., et al.: J. Chem. Soc., Chem. Commun., 15, 1016 (1984)<br></p>

<p>Applications Nitro(trimethylsilyl)acetylene acts as a reagent in the synthesis, reactions, complexes, and properties of nitroalkynes as a unique class of energetic materials. Synthesis of nitro(trimethylsilyl)acetylene.<br>References Windler, G. K., et al.: Synthesis, 46, 2383 (2014); Schmitt, R. J., et al.: Synthesis, 2, 123 (1986)<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications 3-Acetylphenylboronic acid<br></p>

<p>Applications 4-(Cyanophenyl)boronic Acid Pinacol Ester is used to prepare arylparacyclophanes via Suzuki aryl cross-coupling of bromoparacyclophane with arylboronic acid and arylboronates. It’s also used to prepare tyrosine-modified analogs of α4β7 integrin inhibitor biotin-R8ERY.<br>References Roche, A., et al.: Org. Biomol. Chem.,, 3, 515 (2005); Papst, S., et al.: Bioorg. Med. Chem., 20, 5139 (2012)<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Neopentyl Glycol Ester is a useful reagent in lapatinib synthesis.<br>References Radl, S., et al.: PCT Int. Appl. (2014), WO 2014059956 A1<br></p>

<p>Applications m-Carborane, 98% (cas# 16986-24-6) is a useful research chemical.<br></p>

<p>Applications 4-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-2,2-dimethyl-1,3-dioxolane is an intermediate in the synthesis of 1,2-Dioleoyl-rac-glycerol (D482175), which is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.<br>References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)<br></p>

<p>Applications 5-Pyrimidylboronic Acid, is one of the new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.<br>References Saygili N, et al.: Org Biomol Chem. 2004 Mar 21;2(6):852-7. Epub 2004 Feb 23.<br></p>

<p>Applications tert-Butyl (5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate is used as a reactant in the synthesis of BRAF-kinase inhibitors.<br>References Repik, Alexey E., et al.: PCT Int. Appl., WO 2017146604 A1 20170831 (2017)<br></p>

<p>Applications Ethynylboronic Acid MIDA Ester is a useful reagent in preparatino of borono-substited 1(2H)-isoquinolinones by rhodium-catalyzed cycloaddition.<br>References Wang, H., et al.: J. Am. Chem. Soc., 134, 19592 (2012);<br></p>

<p>Applications 4-Carboxymethylphenylboronic acid<br></p>

<p>Applications 3-(2-Hydroxypropan-2-yl)phenylboronic acid<br></p>

<p>Applications (4-((4aR)-7-(Benzyloxy)-3,4,4a,5-tetrahydro-2H-chromen-3-yl)phenoxy)(tert-butyl)dimethylsilane is an protected intermediate in the synthesis of isoflavone Daidzein (D103500) related compounds.<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (2,5-Dimethylphenyl)boronic Acid is a useful synthetic intermediate. It can be used to prepare fluorenones/indenofluorenediones.<br>References Liu, T., et al.: Org. Lett., 13, 2452 (2011)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-phenyl-2-[(trimethylsilyl)oxy]acetonitrile (cas# 25438-37-3) is a useful research chemical.<br></p>

<p>Applications (5-Formylfuran-2-yl)boronic Acid is a reagent used in Suzuki cross-couplings with deactivated aryl bromides and activated aryl chlorides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trinh, T. N., et al.: Org. Biomol. Chem., 12, 9562-9571 (2014);<br></p>

<p>Applications 3-O-tert-Butyldimethylsilyl-cholest-5-ene-3-ol 24-(2-hydroxyisopropyl) 24-Phenyl Sulfinate is an intermediate in the preparation of Campesterol (C155360).<br></p>

<p>Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.<br></p>

<p>Applications Nitrosyl Tetrafluoroborate is a reagent in the formation of miRNA-34a-conjugated magnetic nanovectors which shows therapeutic effects by inhibiting cellular migration and invasion through CD44 gene suppression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lee, H., et al.: J. Nanosci. Nanotechnol., 16, 12939-12946 (2016);<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>