Composés organosiliciés

<p>Applications 1,2,2-Trimethylcyclopropyl Boronic Acid is the boronic acid analogue of 1,2,2-Trimethylcyclopropane. Boronic acid derivatives are widely used in several applications in organic synthesis.<br></p>

<p>Applications 4-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-2,2-dimethyl-1,3-dioxolane is an intermediate in the synthesis of 1,2-Dioleoyl-rac-glycerol (D482175), which is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.<br>References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Benzothiophene-5-boronic acid<br></p>

<p>Applications (4-Ethynylphenyl)trimethylsilane (cas# 16116-92-0) is a useful research chemical.<br></p>

<p>Applications 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-butanamine is a reactant that is used for the synthesis of various racemic and biotinylation of azamacrocycles.<br>References Krivickas, S.J., et al.: J. Org. Chem. 72, 8280 (2007).<br></p>

<p>Applications 2-Hydroxyphenylboronic acid<br></p>

<p>Applications 5-Bromopentylboronic Acid<br></p>

<p>Applications Ethynylboronic Acid MIDA Ester is a useful reagent in preparatino of borono-substited 1(2H)-isoquinolinones by rhodium-catalyzed cycloaddition.<br>References Wang, H., et al.: J. Am. Chem. Soc., 134, 19592 (2012);<br></p>

<p>Applications 4-(Dihydroxyborophenyl)acetylene is a reagent used in organic synthesis . It is used in the preparation of purine analogs as PI4K IIIβ inhibitors used in cancer treatment. As well, used in the preparation of demethylase inhibitors for their potential as anti-tumor drugs.<br>References Sala, M. et al. Bioorg. Med. Chem. Lett., 26, 2706 (2016); Wu, F. et al.: J. Med. Chem., 59, 253 (2016);<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications It is used for synthesis of unsymmetrical biaryls via aromatic C-H borylation-cross-coupling sequence.<br>References Stephens, T. et al.: Org. Lett., 19, 3498 (2017);<br></p>

<p>Applications 3-Acetylphenylboronic acid<br></p>

<p>Impurity Paclitaxel - In House Impurity<br>Applications Protected Baccatin III. Paclitaxel - In House Impurity.<br></p>

<p>Applications 3,4-Dihydro-2H-1,4-benzoxazine-7-boronic acid pinacol ester is a useful intermediate for the synthesis of naphthamides which functions as VEGFR-2 kinase inhibitors for cancer treatment.<br>References Lv, Y., et al.: ACS Med. Chem. Lett., 5, 592 (2014)<br></p>

<p>Applications 4-(2-Ethoxy-2-oxoethoxy)phenylboronic acid<br></p>

<p>Applications m-Carborane, 98% (cas# 16986-24-6) is a useful research chemical.<br></p>

<p>Applications Dibenzothiophene-2-boronic acid is a useful reagent for organic synthesis and other chemical processes.<br>References Duncton, M. A. J., et al.: Org. Lett., 10, 3259 (2008)<br></p>

<p>Applications Trichloro[2-(chloromethyl)-2-propen-1-yl]silane is an intermediate used in the synthesis of 2-​(Chloromethyl)​allyl-​trimethylsilane (C371430), which is one of the reagents to synthesize Leucasandrolide A Macrolide (I) via Mukaiyama aldol coupling.2-​(Chloromethyl)​allyl-​trimethylsilane was used in catalytic Sakurai reaction of α,​β-​enones.<br>References Kopecky, D., et al.: J. Am. Chem. Soc., 123, 8420 (2001).Lee, P., et al.: J. Org. Chem., 66, 8646 (2001).<br></p>

<p>Applications 5-(Ethoxycarbonyl)thiophene-3-boronic Acid is a useful reagent for preparing hydroxyimino(phenyl)propanones as GPBAR1 agonists.<br>References Bissantz, C., et al.: U.S. Pat. Appl. Publ. (2012), US 20120010190 A1<br></p>

<p>Applications 4-tert-Butoxyphenylboronic Acid is a compound used in the preparation of nitrophenylphenol via cross-coupling reaction of nitrohalobenzenes with phenylboronic acids and deprotection.<br>References Kumamoto, N., et al.: Preparation of nitrophenylphenol, JP 2001055360 (2001);<br></p>

<p>Applications 4-Carboxyphenylboronic acid is a reagent used in suzuki coupling reactions.<br>References Hu, Z., et al.: Wuji Huaxue Xuebao, 34, 387 (2018); Ibrahim, M., et al.: J. Organomet. Chem., 859, 44 (2018); Erami, R. S., et al.: Catalysts, 7, 76 (2017)<br></p>

<p>Applications Thiazol-4-ylboronic acid (cas# 1016642-07-1) is a useful research chemical.<br></p>

<p>Applications 5-Aminoboronphthalide is used as a reactant in the preparation of 2,1-benzoxaborole peptide isoquinoline derivatives as HCV NS3 protease inhibitors. It is also used as reactant in the synthesis of nanocarrier for chemomechanically driven guest delivery fueled by intracellular ATP.<br>References Li, X., et al.: Bioorg. Med. Chem. Lett., 21, 2048 (2011); Biswas, S., et al.: Nat. Chem., 5, 613 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester<br></p>

<p>Applications 2-Cyclohexylvinylboronic Acid is used in the synthesis of vinylbenziodoxolones, a novel type of hypervalent iodine(III) reagents.<br>References Stridfeldt, E., et al.: Chem. Eur. J., 22, 16066-16070 (2016)<br></p>

<p>Applications 2,5-Dimethylthiophene-3-boronic acid<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Pfefferkorn, J., et al.: J. Med. Chem., 51, 31 (2008);<br></p>

<p>Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal (cas# 89922-82-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications 4-Carboxymethylphenylboronic acid<br></p>

<p>Applications trans-Campestanyl 3-(4-(tert-Butyldimethylsilyl)oxy)-ferulate is an intermediate used in the synthesis of trans-Campestanyl Ferulate (C155308), which is used for synthesis of trans-feruloyl-β-sitostanol.<br>References Condo, A., et al.: J. Agric. Food Chem., 49, 4961 (2001);<br></p>

<p>Applications 3-(2-Hydroxypropan-2-yl)phenylboronic acid<br></p>

<p>Stability Volatile<br>Applications Allyltrimethylsilane is used in the allylation of aldehydes, imines, allylic and benzylic alcohols, and chiral α-keto-amides that are derived from (S)-proline esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yadav, J.S., et al.: Tetrahedron Lett., 43, 3783 (2002); Aggarwal, V.K., et al.: Tetrahedron Lett., 37, 3745 (1996); Wang, D.K., et al.: J. Org. Chem., 64, 4233 (1999); Kaur, G., et al.: Tetrahedron Lett., 38, 2521 (1997); Soai, K., et al.: J. Chem. Soc., Chem. Commun., 15, 1016 (1984)<br></p>

<p>Applications Bromotrimethylsilane is used as a reagent in the synthesis of α-carboxy nucleoside phosphonate analogs as HIV reverse transcriptase-targeting agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keane, S.J., et al.: J. Org. Chem., ahead of print (2014)<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>

<p>Applications TETRAMETHYLAMMONIUM BOROHYDRIDE (cas# 16883-45-7) is a useful research chemical.<br></p>

<p>Applications Isopropenylboronic Acid Pinacol Ester, can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes.<br>References Salaun, J. et al.: Topics in Curr. Chem. 1, 144 (1988); Chen, J. et al.: J. Amer. Chem. Soci., 135, 5316 (2013);<br></p>

<p>Applications 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopent-2-en-1-one (cas# 1370008-65-3) is a useful research chemical.<br></p>

<p>Applications tert-Butylmethoxydimethylsilane is used as a reactant in the preparation of chlorosilanes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Masaoka, S., et al.: J. Organomet. Chem., 691, 174 (2006);<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Allylboronic acid pinacol ester<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.<br>References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)<br></p>

<p>Applications (2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer<br>References Hutschenreuter, T. et al.: J. Enz. Inhib. Med. Chem., 19, 17 (2004);<br></p>

<p>Applications Perphenylcyclopentasilane is an intermediate in the synthesis of Cyclopentasilane (C988380), a reagent used for depositing silicon on surfaces for electronics applications.<br>References Morisaki, Y., et al.: Chem. Lett., 38, 498 (2009);<br></p>

<p>Applications Dimethoxy(methyl)silane (cas# 16881-77-9) is a useful research chemical.<br></p>

<p>Applications 1,1,3,3-Tetramethyldisiloxane is an organosilane reducing agent and can be used in several reduction reactions including reductive formation of sulfides and reductive etherification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pesti, J., et al.: Org. Process Res. Dev., pages ahead of print (2016);<br></p>

<p>Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.<br></p>

<p>Applications Di(p-anisyl)iodonium Tetrafluoborate (cas# 1426-58-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,1,1,5,7,7,7-Heptamethyl-3,3-bis[(trimethylsilyl)oxy]tetrasiloxane is used in the analysis of organosilicon compounds (eg hexamethyldisiloxane) using gas chromatography or mass spectrometry.<br>References Wurst, M., et al.: Chromatographia, 6, 359 (1973), Wurst, M.: Chemicky Prumysl, 22, 124 (1972)<br></p>

<p>Applications (2,5-Dimethylphenyl)boronic Acid is a useful synthetic intermediate. It can be used to prepare fluorenones/indenofluorenediones.<br>References Liu, T., et al.: Org. Lett., 13, 2452 (2011)<br></p>

<p>Applications Tetrabutylammonium tetrafluoroborate (cas# 429-42-5) is a useful research chemical.<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate is used in synthesis of 1-Alkynyl(triphenyl)arsonium Tetrafluoroborates by onium transfer reaction of 1-Alkynyl(phenyl)iodonium Tetrafluoroborates with Triphenylarsine. Also, used in preparation of Furan- and Thiophene-substituted alkynes and alkynyl ketones by Copper Iodide-catalyzed coupling and carbonylation of Heterocyclic Boronic Acids with Alkynyliodonium salts.<br>References Nagaoka, T., et al.: Tetrah. Lett., 36, 261-4 (1995); Yu, Chan-Mo, et al.: Synlett, 2631-2634 (2005);<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing.<br>References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)<br></p>

<p>Stability Hygroscopic<br>Applications 2-(4-ethenylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane<br></p>

<p>Applications Stigmasteryl-O-tert-butyldimethylsilane Ferulate is an intermediate used in the synthesis of Stigmasteryl Ferulate (S686768), which is used for purification and identification of components of γ-oryzanol in rice bran oil.<br>References Xu, Z., et al.: J. Agric. Food Chem., 47, 2724 (1999);<br></p>

<p>Bromotrimethylsilane is an inhibitor of the enzyme hydroxyl methyl transferases. It binds to the penicillin-binding protein and inhibits the activity of this enzyme, which is involved in the synthesis of bacterial cell walls. Bromotrimethylsilane has been shown to be active against murine sarcoma virus and other viruses as well as bacterial growth. This compound has also been shown to inhibit the growth of several types of cancer cells, including leukemia cells from mice.</p>

<p>Bis(trimethylsilyl)acetylene (bis-TMS) is a reactive ancillary that can be used in polymerization reactions as an initiator. The bis-TMS is prepared by reaction of trimethylsilyl chloride with acetylene to form the trimethylsilyl acetylene, which is then reacted with copper to generate the bis-TMS. Bis-TMS reacts with nucleophiles such as alcohols and amines to produce polymers through a nucleophilic attack. It also has been used for sample preparation for NMR spectra. Bis-TMS is a synthetic compound that has been characterized using nmr spectroscopy and analytical methods. The molecular formula of bis-TMS is C8H16Si2 and its molecular weight is 196.13 g/mol. The chemical structure of bis-TMS consists of two benzyl groups connected by a single carbon bond at the 3 o'clock position on the central</p>

<p>Dichloro(methyl)octadecylsilane is a liquid that is used to coat the inside of tubes in chromatographic columns. The coating ensures that the stationary phase (the material on which the analyte travels) remains stationary and is not carried away with the mobile phase. It has been shown to be effective at removing hydrogen chloride from water and can be used as a fabricating agent for coatings. Dichloro(methyl)octadecylsilane is used in analytical chemistry, where it has been shown to have a number of uses including being able to remove hydroxy groups from molecules and electron microscopy, where it can be used as a coating for nonpolar solvents.</p>

<p>Diethylsilane is a chemical species that has a high value. It is an inorganic compound that contains silicon and boron, which are both chemical elements. Diethylsilane has been shown to react with hydroxy groups on the surface of many different materials, such as aluminum oxide or steel. The reaction between diethylsilane and the hydroxyl group results in the formation of silicon-hydrogen bonds, which are strong and stable. This reaction mechanism can be used for synthesizing solids with high values, such as boron nitride.</p>

<p>Trimethylsilyl isocyanate (TMISC) is a 5-membered heteroaryl. It has been shown to bind to the receptor and shows activity in vitro. TMISC has been reported as a potential drug for bowel disease, congestive heart, and inflammatory bowel disease. TMISC binds to the protein receptor with high affinity, but its binding affinity decreases when it is combined with trifluoroacetic acid or palladium-catalyzed coupling. TMISC can be used to synthesize degarelix acetate, which is an anti-androgen drug that is used in the treatment of prostate cancer.</p>

<p>Triethoxy(propyl)silane is an organosilicon compound that has reactive properties. It is a polymeric material that can be used as a component in paints, coatings, and sealants. The reaction of triethoxy(propyl)silane with sodium hydroxide solution yields hydrogen fluoride, water vapor, and hydrochloric acid. Triethoxy(propyl)silane has been shown to react with hydroxide solution to form polycarboxylic acids. The hydroxyl group on the triethoxy(propyl)silane molecule is responsible for the transport properties of this compound.</p>

<p>Please enquire for more information about 4-(4-Oxopiperidine-1-carbonyl)phenylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N,N-Dimethyl 4-boronobenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethoxyphenylboronic acid is a triazine compound which inhibits inflammation by inhibiting the kinase that catalyzes the phosphorylation of arachidonic acid. It also inhibits lipid kinase, which is involved in the metabolism of lipids, and it has been shown to inhibit cancer cell growth through hydrogen bond interactions with DNA. Ethoxyphenylboronic acid has been shown to have anti-inflammatory properties and may be useful for the treatment of inflammatory diseases such as arthritis. The compound can also inhibit hydrogen peroxide-induced oxidative damage in cells, due to its ability to release intracellular glutathione.</p>

<p>Dimethylphenylsilane is a chemical compound that belongs to the group of trifluoroacetic acid derivatives. It is used as an antimicrobial agent and has been shown to be effective against Gram-positive bacteria, Gram-negative bacteria, and yeast. Dimethylphenylsilane has been shown to inhibit the proliferation of microorganisms by binding to the hydroxyl group in methacrylates and irreversible oxidation of unsaturated alkyl compounds. The reaction mechanism for this process is still unclear but it is thought that it may involve a transfer reaction or a reaction intermediate. Dimethylphenylsilane can be used as a solid catalyst in reactions involving unsaturated alkyl compounds.</p>

<p>Trimethylsilylmethanethiol (TMSET) is a thiol that is used as a reagent in organic synthesis. It is soluble in water and it has a high boiling point, making it useful for reactions that require heat. TMSET has been shown to be an effective antiviral agent against hepatitis C virus (HCV) and influenza A virus by binding to the viral receptor on the cell surface and preventing its entry into the cell. TMSET also inhibits neuronal function by binding to the hydroxy group of proteins, thereby disrupting their structure and function.</p>

<p>6-Methoxypyridine-2-boronic acid is a boronate ligand that can be used to form coordination complexes with metals. It has been shown to interact with silver ions, which are the most effective ligands for enhancing the fluorescence of organic dyes. 6-Methoxypyridine-2-boronic acid is able to rigidify organic molecules by binding to their steric and electronic properties, making them more resistant to photodegradation. This property makes it an excellent candidate for the use in the development of fluorescent labels in analytical chemistry.</p>

<p>The trimethylsilyloxy group is a very efficient method for the synthesis of antireflection coatings consisting of metal carbonyls. One such metal carbonyl is tetradentate zirconium oxide. Tetradentate zirconium oxide has been shown to be a good catalyst for the reaction between triflic acid and 1-(trimethylsilyloxy)cyclohexene. The ethyl group on the 1-carbon atom of 1-(trimethylsilyloxy)cyclohexene allows it to coordinate with the zirconium atom in tetradentate zirconium oxide, while the triflic acid acts as an acid catalyst to increase the rate of reaction.</p>

<p>Mesitylboronic acid is a divalent organoboron compound with the molecular formula CHB(O)OH. It is a white solid that is soluble in organic solvents, but not water. Mesitylboronic acid has been used for the palladium-catalyzed cross-coupling of aryl halides and vinylogous esters, yielding substituted pyridines. Mesitylboronic acid also catalyzes the Suzuki coupling reaction of aryl boronic acids and alkenes, producing substituted indoles. This compound has diagnostic applications due to its ability to form a fluorescent complex with certain metal ions. It also plays an important role in insulin resistance due to its ability to form cross-couplings with unsymmetrical boron compounds.</p>

<p>Tetramethylammonium triacetoxyborohydride is a potent antagonist that binds to the active site of hydrogen-bond forming enzymes. It is used in the treatment of bowel disease, as well as other diseases such as cancer, diabetic neuropathy and inflammatory bowel disease. Tetramethylammonium triacetoxyborohydride has been shown to inhibit the growth of certain bacteria by inhibiting their ability to form hydrogen bonds. This chemical can also be used in asymmetric synthesis, which is the process of synthesizing only one enantiomer from a racemic mixture. Tetramethylammonium triacetoxyborohydride can function as an organocatalyst for this process by activating achiral substrates into chiral ones.</p>