Composés organosiliciés

<p>Applications 2-Hydroxyphenylboronic acid<br></p>

<p>Applications (2-Ethynylphenyl)boronic acid<br></p>

<p>Applications 4-Ethylsulfonylphenylboronic acid is used in the discovery of small molecular RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis.<br>References Harris, P. A,, et al.: ACS Med. Chem. Lett., 4, 1238 (2013)<br></p>

<p>Applications 4-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-2,2-dimethyl-1,3-dioxolane is an intermediate in the synthesis of 1,2-Dioleoyl-rac-glycerol (D482175), which is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.<br>References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications 3-Formylphenylboronic Acid is a reactant in the synthesis of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gosmini, R., et. al.: J. Med. Chem., 57, 8111 (2014)<br></p>

<p>Stability Moisture Sensitive<br>Applications n-Octadecyltrichlorosilane (cas# 112-04-9) is a useful research chemical.<br> E0<br></p>

<p>Applications 3,4-Dihydro-2H-1,4-benzoxazine-7-boronic acid pinacol ester is a useful intermediate for the synthesis of naphthamides which functions as VEGFR-2 kinase inhibitors for cancer treatment.<br>References Lv, Y., et al.: ACS Med. Chem. Lett., 5, 592 (2014)<br></p>

<p>Applications tert-Butyldimethyl(4-(nitrosophenyl)butoxy)silane is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which is a useful research chemical.<br></p>

<p>Applications 1-Butenylboronic Acid is a reagent used in the synthesis of polyene natural products.<br>References Lee, S. J., et al.: J. Am. Chem. Soc., 130, 466-468 (2008)<br></p>

<p>Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal (cas# 89922-82-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>

<p>Applications 5-Pyrimidylboronic Acid, is one of the new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.<br>References Saygili N, et al.: Org Biomol Chem. 2004 Mar 21;2(6):852-7. Epub 2004 Feb 23.<br></p>

<p>Applications 1,1,1,5,7,7,7-Heptamethyl-3,3-bis[(trimethylsilyl)oxy]tetrasiloxane is used in the analysis of organosilicon compounds (eg hexamethyldisiloxane) using gas chromatography or mass spectrometry.<br>References Wurst, M., et al.: Chromatographia, 6, 359 (1973), Wurst, M.: Chemicky Prumysl, 22, 124 (1972)<br></p>

<p>Applications 4-(Cyanophenyl)boronic Acid Pinacol Ester is used to prepare arylparacyclophanes via Suzuki aryl cross-coupling of bromoparacyclophane with arylboronic acid and arylboronates. It’s also used to prepare tyrosine-modified analogs of α4β7 integrin inhibitor biotin-R8ERY.<br>References Roche, A., et al.: Org. Biomol. Chem.,, 3, 515 (2005); Papst, S., et al.: Bioorg. Med. Chem., 20, 5139 (2012)<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Allylboronic acid pinacol ester<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Tris(trimethylsilyl)guanine is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Stability Moisture Sensitive<br>Applications Chlorotriethylsilane is used in the preparation of potent silylating agent and lewis acid catalyst. Chlorotriethylsilane derivatived ethers have been shown to be more stable towards hydrolysis than are trimethyl ethers.<br> E0<br>References Alvisi, C. et al.: J. Org. Chem., 63, 1330 (1998): Higashiya, S. et al.: J. Org. Chem., 69, 6326 (2004); Hicks, J.D. et al.: Org. Lett., 9, 5621 (2007);<br></p>

<p>Applications tert-Butylmethoxydimethylsilane is used as a reactant in the preparation of chlorosilanes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Masaoka, S., et al.: J. Organomet. Chem., 691, 174 (2006);<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Applications Ethynylboronic Acid MIDA Ester is a useful reagent in preparatino of borono-substited 1(2H)-isoquinolinones by rhodium-catalyzed cycloaddition.<br>References Wang, H., et al.: J. Am. Chem. Soc., 134, 19592 (2012);<br></p>

<p>Applications N-Pentylboronic Acid is used in the synthesis of (-)-Δ8-THC and (-)-Δ9-THC. Also it aids in the synthesis of boronic acid inhibitors of endothelial lipase.<br>References O'Connell, D. et al.: Bioorg. Med. Chem. Lett., 22, 1397 (2012); Cheng, L. et al.: Org. Lett., 15, 764 (2013);<br></p>

<p>Applications Perphenylcyclopentasilane is an intermediate in the synthesis of Cyclopentasilane (C988380), a reagent used for depositing silicon on surfaces for electronics applications.<br>References Morisaki, Y., et al.: Chem. Lett., 38, 498 (2009);<br></p>

<p>Bis (1,5-Cyclooctadiene) rhodium(I)tetrafluoroborate (BODIPY) is a catalyst that enhances the rate of hydrosilylation reactions. This catalyst has been shown to be effective in the synthesis of aryl chlorides from amines and aldehydes with high enantioselectivity. BODIPY is also immobilized on silica gel to create an active catalyst for asymmetric synthesis. The immobilization process on silica gel is done by reacting BODIPY with ammonium formate and amines. The resulting catalyst can be used for the synthesis of functionalized organic compounds, such as pyrrolidines, tetrahydrofurans, and thiophenes.</p>

<p>Please enquire for more information about 4-(Ethylsulfonyl)phenylboronicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (3-IMidazol-1-yl-propyl)-[4-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]aMine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trichlorooctadecylsilane is a model system that consists of a monolayer of octadecyltrichlorosilane particles. The dispersive solid-phase extraction technique can be used to extract analytes from the surface of this particle. This technique involves removing the solvent from a sample by passing it through an adsorbent. The hydrophobic effect, which is the phenomenon that a nonpolar substance is dissolved in a nonpolar solvent, will cause analytes to bind to the hydrophobic surface of octadecyltrichlorosilane particles because they are hydrophobic.</p>

<p>Please enquire for more information about (3-Chloropropyl)diphenylsulfonium tetrafluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(Difluoromethoxy)phenylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bromotrimethylsilane is an inhibitor of the enzyme hydroxyl methyl transferases. It binds to the penicillin-binding protein and inhibits the activity of this enzyme, which is involved in the synthesis of bacterial cell walls. Bromotrimethylsilane has been shown to be active against murine sarcoma virus and other viruses as well as bacterial growth. This compound has also been shown to inhibit the growth of several types of cancer cells, including leukemia cells from mice.</p>

<p>Please enquire for more information about (5-Chloropyridin-3-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazole is a reagent in organic synthesis. It is an intermediate in the synthesis of pinacol esters and isomers thereof. 1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h pyrazole can be prepared by diazotization with sodium nitrite and hydrochloric acid followed by heating in an alcoholic solution of pinacol. The synthetic method for this compound has been described.br&gt;br&gt; The target product of this chemical reaction is pinacol ester. Pinacol esters are used as intermediates for the synthesis of many other compounds including pharmaceuticals and fragrances. Diazotization with sodium nitrite and hydrochlor</p>

<p>Sodium triacetoxyborohydride is an oxidizing agent that is used in organic synthesis as a reagent for the reduction of esters and nitriles to alcohols and amines, respectively. This compound has been shown to be effective in reducing the activity of ccr5 receptors, which are important in HIV infection. Sodium triacetoxyborohydride can also be used to reduce antibodies, such as monoclonal antibodies, that have been conjugated with drugs or toxins to produce immunotoxins. Sodium triacetoxyborohydride has also been shown to be an effective agent for the treatment of inflammatory bowel disease and cancer therapy. It has been found to be toxic to some bacteria, fungi, and protozoa.</p>

<p>Please enquire for more information about 9,9-Bis(2-ethylhexyl)fluorene-2,7-bis(boronic acidpinacolester) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Methoxypyrimidine-5-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Butyl-3-methylimidazolium terafluoroborate is an ionic liquid that has been used in a number of research applications.</p>

<p>2-Chloro-3-ethylbenzoxazolium tetrafluoroborate is a synthetic compound that inhibits the enzyme maltase. This compound is used in the treatment of diabetic patients with intestinal maltase deficiency and has been shown to be effective in clinical studies. 2-Chloro-3-ethylbenzoxazolium tetrafluoroborate has also been shown to inhibit other enzymes, such as thiocarbamate synthetase and aminooxazoline synthetase, which are involved in the biosynthesis of chlorinated pesticides and herbicides. The chloride ion is necessary for this inhibition activity. The compound can be prepared by a preparative method that involves hexaacetate and chloride ion or by using an aglycone, trehalamine, or stereospecific method.</p>

<p>Please enquire for more information about 3-Chloro-4-cyanophenylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>