Autres inhibiteurs
Cette catégorie englobe une grande variété d'inhibiteurs qui ne rentrent pas dans les classifications standard mais qui sont néanmoins cruciaux pour diverses recherches biochimiques et pharmacologiques. Ces inhibiteurs peuvent cibler des voies, des enzymes et des interactions moléculaires uniques ou moins étudiés, fournissant des outils précieux pour des domaines de recherche spécialisés. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité ciblant de multiples objectifs biologiques et disciplines de recherche, vous permettant d'explorer de nouvelles avenues thérapeutiques et d'approfondir votre compréhension des processus biologiques complexes.
35913 produits trouvés pour "Autres inhibiteurs"
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PX-316
CAS :PX-316: AKT inhibitor, reduces Akt activity by 78% in HT-29 xenografts, effective against MCF-7 and HT-29 cancers, well-tolerated intravenously.Formule :C28H57O10PCouleur et forme :SolidMasse moléculaire :584.72Tezampanel hydrate
CAS :Tezampanel is used for the treatment of migraine, neuropathic pain.Formule :C13H23N5O3Couleur et forme :SolidMasse moléculaire :297.35PF1070A
CAS :PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothioneinFormule :C31H44N4O6Couleur et forme :SolidMasse moléculaire :568.7MI-1851
CAS :MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.Formule :C34H53N15O6Couleur et forme :SolidMasse moléculaire :767.8811-Deoxy-13-deoxodaunorubicin
CAS :11-Deoxy-13-deoxodaunorubicin is an anthracycline antibiotic with activity against Gram-positive, Gram-negative bacteria, and tumors.Formule :C27H31NO8Couleur et forme :SolidMasse moléculaire :497.537ADP-2341
ADP-2341 is a soluble analog of FiVe1.Formule :C24H29Cl2N5O3Couleur et forme :SolidMasse moléculaire :506.43RN941
CAS :RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.Formule :C34H34FN7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :639.68Thalicarpine
CAS :Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.Formule :C41H48N2O8Couleur et forme :SolidMasse moléculaire :696.83Org-31710
CAS :Org-31710 is a progesterone receptor antagonist potentially for contraception.Formule :C30H39NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.64PF-446687
CAS :PF-446687 is a highly selective MC4 receptor (MC4R) agonist.Formule :C28H37ClF2N2O2Couleur et forme :SolidMasse moléculaire :507.0623-De(mycinosyloxy)tylosin
CAS :23-De(mycinosyloxy)tylosin is a macrolide antibiotic exhibiting activity against Gram-positive bacteria, with limited efficacy against Gram-negative bacteria and mycoplasma.Formule :C38H63NO12Couleur et forme :SolidMasse moléculaire :725.91Agarospirol
CAS :Agarospirol has partial anti-inflammatory activity.Formule :C15H26ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :222.37GSK579289A
CAS :GSK579289A is an inhibitor of benzimidazole thiophene.Formule :C26H27ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.04SB 204070 hydrochloride
CAS :SB 204070 hydrochloride is an inhibitor of beta-lactamase, it is isolated from Spondias mombin.Formule :C19H27ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.88Piceid 6″-O-azelaic acid ester
Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.Formule :C24H36O10Couleur et forme :SolidMasse moléculaire :484.54VU6028418
VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).
Couleur et forme :LiquidMRS4865
CAS :MRS4865 (compound 7a) serves as a chimeric antagonist for the P2Y14 receptor and an agonist for UDP-glucose, offering protection against neuropathic pain.Formule :C39H39F3N4O7Couleur et forme :SolidMasse moléculaire :732.74Camptothecin-20(S)-O-propionate
CAS :CZ-48 is a DNA topoisomerase inhibitor.Formule :C23H20N2O5Couleur et forme :SolidMasse moléculaire :404.42NTPDase-IN-3
CAS :NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.Formule :C22H24ClN3OS2Couleur et forme :SolidMasse moléculaire :446.03Neoenactin M2
CAS :Neoenactin M2 exhibits strong antifungal activity against yeasts and filamentous fungi.Formule :C19H38N2O5Couleur et forme :SolidMasse moléculaire :374.52TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Formule :C24H34N4O2SCouleur et forme :SolidMasse moléculaire :442.62AM-9514
CAS :AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.Formule :C18H25N5O4Couleur et forme :SolidMasse moléculaire :375.42MDL-27088
CAS :MDL-27088 is an angiotensin-covering enzyme inhibitor.Formule :C25H28N2O5Couleur et forme :SolidMasse moléculaire :436.50Monamycin B
CAS :Monamycin B is an ester peptide antibiotic with activity against Gram-positive bacteria.Formule :C33H55N7O8Couleur et forme :SolidMasse moléculaire :677.83RS 2135
CAS :RS 2135 is a novel class I antiarrhythmic agent to inhibit ischemia-induced ventricular arrhythmias.Formule :C18H21ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.83BAY-850 HCl
BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.Formule :C38H48Cl5N5O3Couleur et forme :SolidMasse moléculaire :800.08Enpp-1-IN-11
Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.Formule :C15H15N5O3SCouleur et forme :SolidMasse moléculaire :345.38Retezorogant
CAS :Retezorogant is a retinoic acid receptor-related orphan receptor gamma (RORγ) antagonist.Formule :C23H33ClN2O3Couleur et forme :SolidMasse moléculaire :420.97Anticancer agent 78
Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.Formule :C19H14BrNO4Couleur et forme :SolidMasse moléculaire :400.22Oncopterin
CAS :Oncopterin is found in urine from patients with solid and blood cancers.Formule :C12H18N6O3Couleur et forme :SolidMasse moléculaire :294.31SENP2-IN-1
CAS :SENP2-IN-1 selectively inhibits SENP2, SENP1, and SENP5 with low IC50 values; useful in cancer studies.Formule :C32H29N3O5S2Couleur et forme :SolidMasse moléculaire :599.72Sucistil
Sucistil is an active biochemical. hemoglobin sucistil (bovine) is an oxygen carrier [1].Formule :C9H15NO4SCouleur et forme :SolidMasse moléculaire :233.28Celesticetin B
CAS :Celesticetin B is an antibiotic primarily exhibiting antibacterial activity against Gram-positive microorganisms.Formule :C21H38N2O8SCouleur et forme :SolidMasse moléculaire :478.631-Homorifamycin W
CAS :31-Homorifamycin W is an antibiotic discovered in Amycolatopsis mediterranei.Formule :C36H47NO11Couleur et forme :SolidMasse moléculaire :669.758Hypercalin B
CAS :Hypercalin B is an antibacterial agent isolated from the hexane and chloroform extracts of Hypericum acmosepalum. It demonstrates activity against multidrug-resistant strains of Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 0.5 to 128 mg/L.
Formule :C33H42O5Couleur et forme :SolidMasse moléculaire :518.684Antitrypanosomal agent 6
Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.Formule :C22H29Cl2N5OCouleur et forme :SolidMasse moléculaire :450.4Leucomycin U
CAS :Leucomycin U is a macrolide antibiotic. It demonstrates significant activity against Gram-positive bacteria and also exhibits effects on spirochetes, rickettsiae, and chlamydiae.Formule :C37H61NO14Couleur et forme :SolidMasse moléculaire :743.878Fandosentan
CAS :Fandosentan is an endothelin receptor antagonist.Formule :C25H18F3NO6SCouleur et forme :SolidMasse moléculaire :517.47GSK3527497
CAS :GSK3527497 is a novel potent and selective inhibitor of transient receptor potential vanilloid-4 (TRPV4).Formule :C17H16ClFN4O4SCouleur et forme :SolidMasse moléculaire :426.85Cortistatin A
CAS :Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.Formule :C30H36N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.62Holothurinogenin
CAS :Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.Formule :C30H46O4Couleur et forme :SolidMasse moléculaire :470.68Ophiobolin D
CAS :Ophiobolin D is a terpene antibiotic with mild inhibitory effects on Staphylococcus aureus.Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55Ro 0437626
CAS :P2X1 purinergic receptor antagonistFormule :C27H35N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.66ACSS2-IN-1
CAS :ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.Formule :C27H25ClN6O2Couleur et forme :SolidMasse moléculaire :500.98Croconic acid disodium
CAS :Croconic acid (disodium) (Nacr) enhances gene expression related to lysine crotonylation (Kcr) modification, which promotes cell growth and proliferation. This compound also shows promise in boosting somatic cell nuclear transfer (SCNT) efficiency and optimizing research in cell culture conditions.Formule :C5Na2O5Couleur et forme :SolidMasse moléculaire :186.03Gentamicin C1
CAS :Gentamicin C1 is a broad-spectrum aminoglycoside antibiotic with antibacterial activity.Formule :C21H43N5O7Couleur et forme :SolidMasse moléculaire :477.595Antibiotic MA 144M1
CAS :Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formule :C42H55NO15Couleur et forme :SolidMasse moléculaire :813.88ATR-IN-7
CAS :ATR-IN-7 is a potent inhibitor of ATR.Formule :C21H22FN7OCouleur et forme :SolidMasse moléculaire :407.44Methyl Streptonigrin
CAS :Methyl Streptonigrin is an ABCG2 transporter function inhibitor.Formule :C26H24N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.49M-89 MLL inhibitor
CAS :M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.Formule :C37H47N5O4SCouleur et forme :SolidMasse moléculaire :657.87Polyoxin J
CAS :Polyoxin J is a nucleoside antifungal antibiotic, notably effective against sheath blight in rice.Formule :C17H25N5O12Masse moléculaire :491.41Epelmycin C
CAS :Epelmycin C exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal activity against Candida albicans. It also shows activity against leukemia L1210.Formule :C36H45NO14Couleur et forme :SolidMasse moléculaire :715.741Antibacterial agent 70
Antibacterial agent 70 is a new dihydropyrimidinone-imidazole hybrid antimicrobial agent (MIC: 0.5 μg/ml).Formule :C25H32ClN7O6SCouleur et forme :SolidMasse moléculaire :594.08Ataprost
CAS :Ataprost (ONO 41483), an oral Carboprostacyclin analogue, is 2.6x more potent in inhibiting ADP-induced platelet aggregation and can relieve coronary spasm.Formule :C21H32O4Couleur et forme :SolidMasse moléculaire :348.48KNI 10033
CAS :KNI 10033 is a potent inhibitor of HIV proteaseFormule :C40H45N5O7S2Couleur et forme :SolidMasse moléculaire :771.95SLC4101431
SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.Formule :C29H28ClN7OSCouleur et forme :SolidMasse moléculaire :558.1MDL-27210
CAS :MDL-27210 is the ethyl ester prodrug of a potent angiotensin-converting enzyme inhibitor, MDL-27088.Formule :C27H32N2O5Couleur et forme :SolidMasse moléculaire :464.55Resorcinomycin B
CAS :Resorcinomycin B is an antibiotic found in [Streptoverticillum roseoverticillatum].
Formule :C13H18N4O5Couleur et forme :SolidMasse moléculaire :310.306CPX-351
CAS :CPX-351 (Vyxeos) is a liposomal encapsulant of cytarabine and Zoerythromycin with potential antitumor activity.Formule :C36H42N4O15Degré de pureté :98.95% - 99.763%Couleur et forme :SolidMasse moléculaire :770.74Miyakamide B2
CAS :Miyakamide B2 is an antibiotic with insecticidal properties. It suppresses the growth of brine shrimp and shows weak activity against Xanthomonas species. The IC50 for inhibition of P388 cells by Miyakamide B2 is 7.6 μg/mL.Formule :C31H32N4O4Couleur et forme :SolidMasse moléculaire :524.61PTP1B-IN-17
PTP1B-IN-17, a benzimidazole derivative, inhibits PTP1B (Ki: 30.2 μM) and may help study type 2 diabetes.Formule :C26H19N3O4SCouleur et forme :SolidMasse moléculaire :469.51Citrinin hydrate
CAS :Citrinin hydrate is an inhibitor of human rhinovirus (HRV) 3C protease, with an IC50 of 1.0 mM.Formule :C13H16O6Couleur et forme :SolidMasse moléculaire :268.263ADH-353
CAS :ADH-353 inhibits Aβ fibrillization and mitigates Aβ-induced cytotoxicity in SH-SY5Y and N2a cells, making it useful for studies related to Alzheimer's disease.Formule :C27H38N8O6Couleur et forme :SolidMasse moléculaire :570.64PI3K-IN-26
CAS :PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.Formule :C21H18N6OSCouleur et forme :SolidMasse moléculaire :402.47JBIR-22
CAS :JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.Formule :C23H33NO6Couleur et forme :SolidMasse moléculaire :419.51SOS1-IN-6
CAS :SOS1-IN-6 (compound 33-P1) is a potent inhibitor of SOS1, acting on SOS1-G12D (IC50: 14.9 nM) and SOS1-G12V (IC50: 73.3 nM).Formule :C26H28F3N3O2Couleur et forme :SolidMasse moléculaire :471.51Oudenone
CAS :Oudenone is an oxygen-containing heterocyclic antibiotic with mild antibacterial and antifungal properties. It also exhibits antihypertensive effects in rats with spontaneous hypertension.Formule :C12H16O3Couleur et forme :SolidMasse moléculaire :208.254Cystothiazole A
CAS :Cystothiazole A exhibits antifungal properties, effectively inhibiting Candida albicans, Saccharomyces cerevisiae, and Aspergillus fumigatus with minimum inhibitory concentrations (MIC) of 0.4 μg/mL, 0.1 μg/mL, and 1.6 μg/mL, respectively. It also demonstrates inhibitory activity against human tumor cells such as HPT-116 and K562, with MIC values of 130 ng/mL and 110 ng/mL. However, it shows no antibacterial activity.Formule :C20H26N2O4S2Couleur et forme :SolidMasse moléculaire :422.561FPR2 agonist 2
Potent FPR2 agonist, crosses blood-brain barrier, EC50: 0.13 nM; reduces inflammation and mitochondrial dysfunction, inhibits caspase-3.Formule :C25H20F2N4O2Couleur et forme :SolidMasse moléculaire :446.45ZIKV-IN-5
ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.Formule :C36H45NO4SiCouleur et forme :SolidMasse moléculaire :583.83Butaprost
CAS :Butaprost: EP2 receptor agonist, EC50=33 nM, Ki=2.4 μM (murine), reduces fibrosis via TGF-β/Smad2.Formule :C24H40O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.57GSK2945 hydrochloride
GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.Formule :C20H19Cl3N2O2SCouleur et forme :SolidMasse moléculaire :457.8Monamycin D1
CAS :Monamycin D1 is a lipopeptide antibiotic with activity against Gram-positive bacteria.Formule :C34H57N7O8Masse moléculaire :691.86ZK168281
CAS :ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.Formule :C32H46O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.70MC4355
MC4355 is a dual inhibitor of EZH2 and histone deacetylase (HDAC).Formule :C30H36N4O5Couleur et forme :SolidMasse moléculaire :532.63Anticancer agent 26
Anticancer agent 26 is a promising candidate for cancer therapy and deserves further development.Formule :C28H33NO5Couleur et forme :SolidMasse moléculaire :463.57MSX-3 free acid
CAS :MSX-3 free acid is an A2A adenosine receptor antagonist and a prodrug of MSX-2.Formule :C21H23N4O7PCouleur et forme :SolidMasse moléculaire :474.40Basroparib
CAS :Basroparib is an inhibitor of ribose polymerase (PARP) and has shown antitumour effects.Formule :C18H21F2N7O3Couleur et forme :SolidMasse moléculaire :421.4Dioxamycin
CAS :Dioxamycin exhibits activity against Gram-positive bacteria and inhibits Staphylococcus aureus 209P with a minimum inhibitory concentration (MIC) of 3.12 μg/mL. It also suppresses the proliferation of L1210, P388, IMC, LX-1, and SC-6 cells with IC50 values (μg/mL) of 2.7, 1.4, 6.0, 2.0, and 2.5, respectively.Formule :C38H40O15Couleur et forme :SolidMasse moléculaire :736.715Ornoprostil
CAS :Ornoprostil, a prostaglandin E1 analogue, acts as a mucosal protectant.Formule :C23H38O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.54Hcyb1
Hcyb1 specifically inhibits PDE2A with 0.57 μM IC50, over 250x selective, and has neuroprotective and antidepressant effects.Formule :C24H20N4OCouleur et forme :SolidMasse moléculaire :380.44Hitachimycin
CAS :Hitachimycin is a macrolide antibiotic with properties that inhibit the growth of tumor cells and exhibit antiprotozoal activity.Formule :C29H35NO5Couleur et forme :SolidMasse moléculaire :477.592Mollisin
CAS :Mollisin is a quinone antibiotic with antifungal properties.Formule :C14H10Cl2O4Couleur et forme :SolidMasse moléculaire :313.133DAD dichloride
DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.Formule :C26H42Cl2N6OCouleur et forme :SolidMasse moléculaire :525.56CXCR4 probe 1
CAS :CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.Formule :C24H30FN5O4SCouleur et forme :SolidMasse moléculaire :502.59Fudecalone
CAS :Fudecalone is produced by the Penicillium strain FO-2030. It completely inhibits the coccidian parasite Eimeria Tenella that is resistant to Monensin.Formule :C15H22O3Couleur et forme :SolidMasse moléculaire :250.33Epithienamycin D
CAS :Epithienamycin D is a carbapenem antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria.Formule :C13H16N2O5SCouleur et forme :SolidMasse moléculaire :312.342Halomicin B
CAS :Halomicin B is an ansamycin-type antibiotic effective against both Gram-positive and Gram-negative bacteria.Formule :C43H58N2O12Couleur et forme :SolidMasse moléculaire :794.927TP-030-2
CAS :TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .Formule :C23H21BrN4O3Couleur et forme :SolidMasse moléculaire :481.34Trilobolide
CAS :Trilobolide is a natural counterpart of thapsigargin and an activator of cytokine secretion.Formule :C27H38O10Couleur et forme :SolidMasse moléculaire :522.58Clavalanine
CAS :Clavalanine (Ro 22-5417) is capable of inhibiting various bacteria and fungi.Formule :C8H12N2O4Couleur et forme :SolidMasse moléculaire :200.192BMS-520
CAS :BMS-520: potent oral S1P1 agonist, effective in rat arthritis and mouse multiple sclerosis model.Formule :C23H17F3N4O4Couleur et forme :SolidMasse moléculaire :470.4Anticancer agent 79
Anticancer agent 79 (3d) has potent activity against breast cancer, with cytotoxic effects on T47-D, IC50=13.64±0.26μM.Formule :C20H12F3NO5Couleur et forme :SolidMasse moléculaire :403.31Namitecan
CAS :Namitecan is an effective inhibitor of topoisomerase I. It has antitumor property.Formule :C23H22N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.44Trk-IN-7
Trk-IN-7 inhibits TRKA/B/C (IC50: 0.25-10 nM) & EML4-ALK (<15 nM), also targets various ALK mutations (IC50: 5-50 nM).
Formule :C18H17FN6O2Couleur et forme :SolidMasse moléculaire :368.36Hydranthomycin
CAS :Hydranthomycin is an antibiotic with moderate antifungal activity, exhibiting a minimum inhibitory concentration (MIC) of 25 μg/mL against the rice blast fungus. Additionally, it inhibits the growth of Chlorella (tiny naked algae) and possesses herbicidal properties.Formule :C20H20O5Couleur et forme :SolidMasse moléculaire :340.37Oxamicetin
CAS :Oxamicetin is a nucleoside antibiotic with antibacterial and antimycobacterial properties.Formule :C29H42N6O10Couleur et forme :SolidMasse moléculaire :634.678BMS-681
CAS :BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.Formule :C26H36F3N5OCouleur et forme :SolidMasse moléculaire :491.59Glucoallosamidin B
CAS :Glucoallosamidin B is a glycoside antibiotic identifiable in the Streptomyces species strain (Streptomycessp. SA-684). It functions as an inhibitor of chitinase activity. Experiments demonstrate that Glucoallosamidin B significantly inhibits the chitinase of Candida albicans (ATCC 10231), with an IC50 value of 0.8 μg/mL.
Formule :C25H42N4O14Couleur et forme :SolidMasse moléculaire :622.619Neoenactin A
CAS :Neoenactin A exhibits potent activity against yeasts and filamentous fungi.Formule :C19H36N2O5Couleur et forme :SolidMasse moléculaire :372.5Norplicacetin
CAS :Norplicacetin exhibits activity against Gram-positive bacteria and mycobacteria.Formule :C24H33N5O7Masse moléculaire :503.55Isoleucyl tRNA synthetase-IN-2
CAS :Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).Formule :C22H33N5O8SCouleur et forme :SolidMasse moléculaire :527.59Chitinovorin C
CAS :Chitinovorin C is a β-lactam class antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.Formule :C15H20N4O8SCouleur et forme :SolidMasse moléculaire :416.406SOAT-IN-1
CAS :SOAT-IN-1 (compound 40) is a potent and selective inhibitor targeting the sodium-dependent organic anion transporter (SOAT), exhibiting IC50 values of 1.6 µM for SOAT and 14.3 µM for NTCP.Formule :C20H16ClN3O6SCouleur et forme :SolidMasse moléculaire :461.88Mumbaistatin
CAS :Mumbaistatin is an inhibitor of the glucose-3-phosphate translocase enzyme found in the bacterium Streptomyces (Streptomyces DSM 11641).Formule :C28H20O12Couleur et forme :SolidMasse moléculaire :548.45MEIS-IN-1
CAS :MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.Formule :C24H21F3N2O4Couleur et forme :SolidMasse moléculaire :458.43TA-316
CAS :Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.Formule :C28H25BrN4O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.562-Acetoxyacorenone
CAS :2-Acetoxyacorenone (compound 8) is a sesquiterpenoid compound that can be isolated from the rhizomes of Acorus tatarinowii. It exhibits potential inhibition activity against AChE and β-BACE1, making it useful for Alzheimer's disease research.Formule :C17H26O3Couleur et forme :SolidMasse moléculaire :278.39J-104118
CAS :J-104118 potentially inhibits squalene synthase.Formule :C28H26Cl2FNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.41Evategrel
CAS :Evategrel is an inhibitor of platelet aggregation.Formule :C21H26ClNO7SCouleur et forme :SolidMasse moléculaire :471.95DJT06001
CAS :DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.Formule :C21H20ClN3O5SCouleur et forme :SolidMasse moléculaire :461.92FTI-2628
CAS :FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.Formule :C31H34N4O3SCouleur et forme :SolidMasse moléculaire :542.69Copper(II) ionophore I
CAS :Copper(II) ionophore I is an active compound.Formule :C26H44N2S4Couleur et forme :SolidMasse moléculaire :512.90Anticancer agent 28
Anticancer agent 28 is 50x more potent than Oridonin, IC50 of 0.09 μM against K562; effective in H22 mouse tumors.Formule :C28H33NO6Couleur et forme :SolidMasse moléculaire :479.56Dihydrokainic acid
CAS :EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptakeFormule :C10H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.25CI 922
CAS :CI 922 is an anaphylaxis mediator release inhibitor. It inhibits the activation of human neutrophils.
Formule :C26H30N10O6Couleur et forme :SolidMasse moléculaire :578.58CV 5975
CAS :CV 5975 is a nonsulfhydryl ACE inhibitor that was investigated for use in hypertension and heart failure.Formule :C22H31N3O5SCouleur et forme :SolidMasse moléculaire :449.56Cytosaminomycin B
CAS :Cytosaminomycin B exhibits activity against Eimeria Tenella coccidia.Formule :C26H37N5O8Couleur et forme :SolidMasse moléculaire :547.601MK-8318
CAS :MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Formule :C27H26F4N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5VEGFR-2-IN-26
CAS :VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.Formule :C24H19F3N6O2Couleur et forme :SolidMasse moléculaire :480.44Carmegliptin dihydrochloride
CAS :Carmegliptin dihydrochloride (RG-1579, RO4876904) is a salt of Camegliptin, a DPP-4 inhibitor for type 2 diabetes.Formule :C20H30Cl2FN3O3Couleur et forme :SolidMasse moléculaire :450.38Amrubicin HCl
CAS :Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.Formule :C25H25NO9Couleur et forme :SolidMasse moléculaire :483.47Cyclo (D-Pro-L-Val)
CAS :Cyclo(D-Pro-L-Val) inhibits the activity of β-glucosidase (β-glycosidase) with an IC50 of 75 μg/mL and exhibits either no inhibitory effects or only weak inhibition on other glycosidases.Formule :C10H16N2O2Couleur et forme :SolidMasse moléculaire :196.246Aspochalasin M
CAS :Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.544"-Demethylgentamicin C2
CAS :4"-Demethylgentamicin C2 exhibits activity against both Gram-positive and Gram-negative bacteria.Formule :C19H39N5O7Couleur et forme :SolidMasse moléculaire :449.54Monorden E
CAS :Monorden E induces cell cycle arrest in Jurkat cells at both the G1 and G2/M phases and exhibits antifungal activity against Aspergillus niger.Formule :C18H21ClO5Couleur et forme :SolidMasse moléculaire :352.81Sequoiaflavone
CAS :Sequoiaflavone is a biflavone isolated from Ginkgo biloba.Formule :C31H20O10Couleur et forme :SolidMasse moléculaire :552.48Antibacterial agent 69
Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).Formule :C24H19N3O4SCouleur et forme :SolidMasse moléculaire :445.492,3-dinor-11β-Prostaglandin F2α
CAS :2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, whereFormule :C18H30O5Couleur et forme :SolidMasse moléculaire :326.43VEGFR-2-IN-12
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 (IC50: 0.037 μM). VEGFR-2-IN-12 has anti-tumour effects.Formule :C22H24N6O3SCouleur et forme :SolidMasse moléculaire :452.53Balanol
CAS :Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.Formule :C28H26N2O10Couleur et forme :SolidMasse moléculaire :550.51Napyradiomycin A2
CAS :Napyradiomycin A2 is an antibiotic that exhibits activity against Gram-positive bacteria and mycobacteria.Formule :C25H30Cl2O6Couleur et forme :SolidMasse moléculaire :497.408MDL-43291
CAS :MDL-43291 is a leukotriene receptor antagonist.Formule :C25H42O4SCouleur et forme :SolidMasse moléculaire :438.66Gabaculine
CAS :Gabaculine can be found in Streptomyces toyocaensis, and it inhibits GABA aminotransferase.Formule :C7H9NO2Masse moléculaire :139.152trans-Doxercalciferol
CAS :trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.Formule :C28H44O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.65Vindeburnol
CAS :Vindeburnol is a cerebral vasodilator vincamine analog that bears neuroprotective properties.Formule :C17H20N2OCouleur et forme :SolidMasse moléculaire :268.35CHNQD-01255
CAS :CHNQD-01255 is an orally active inhibitor of Arf-GEFs that is effective against hepatocellular carcinoma (HCC).
Formule :C23H29NO6Couleur et forme :SolidMasse moléculaire :415.48Papyracon D
CAS :Papyracon D exhibits moderate inhibitory effects on L1210 and HL60 cells and shows mild inhibition against nematodes. It also has a slight inhibitory effect on Gram-positive bacteria.Formule :C14H18O5Masse moléculaire :266.29MV061194
CAS :MV061194 is a potent and selective cathepsin K (Cat K) inhibitor.Formule :C28H37N5O4SCouleur et forme :SolidMasse moléculaire :539.69Nispomeben
CAS :Nispomeben is an effective non-opioid analgesic.Formule :C21H27NO4Couleur et forme :SolidMasse moléculaire :357.44NNTA
CAS :NNTA is a highly selective and potent activator of μ/κ-opioid heteromers.Formule :C31H32N2O4Couleur et forme :SolidMasse moléculaire :496.60Axl-IN-3
Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases.Formule :C24H25ClN6O2Couleur et forme :SolidMasse moléculaire :464.95Fumaryl-DL-alanine
CAS :Fumaryl-DL-alanine exhibits activity against Gram-positive bacteria.Formule :C7H9NO5Couleur et forme :SolidMasse moléculaire :187.15KOS-1584
CAS :KOS-1584, a safer, more effective epothilone, inhibits cell division by stabilizing microtubules and evading P-gp.Formule :C27H39NO5SCouleur et forme :SolidMasse moléculaire :489.67P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.4Longicoricin
CAS :Longicoricin is a monotetrahydrofuran Annonaceous acetogenin from Asimina longifolia.Formule :C37H68O6Couleur et forme :SolidMasse moléculaire :608.93Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66Arverapamil
CAS :Arverapamil is a chiral metabolite of Verapamil.Formule :C26H36N2O4Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :440.58ITK inhibitor 6
CAS :ITK inhibitor 6 selectively targets ITK, BTK, JAK3, EGFR, LCK, blocks PLCγ1 and ERK1/2 phosphorylation, and inhibits cell proliferation.Formule :C28H24F2N4O2Couleur et forme :SolidMasse moléculaire :486.515(S),6(S)-DiHETE
CAS :5(S),6(S)-DiHETE: a 5,6-dihydroxy acid from LTA4 hydrolysis, lacks leukotriene activity.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Schidigera-genin B
CAS :Schidigera-genin B is a steroidal saponin that can be isolated from Yucca glauca. It exhibits mild antifungal activity.Formule :C27H40O4Couleur et forme :SolidMasse moléculaire :428.604Pluracidomycin C1
CAS :Pluracidomycin C1 is a carbapenem antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria and also possesses β-lactamase inhibitory properties.Formule :C10H13NO10S2Couleur et forme :SolidMasse moléculaire :371.341ORP-101
CAS :ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.Formule :C60H84N2O8Couleur et forme :SolidMasse moléculaire :961.32Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :531.17Asperenone
CAS :Asperenone is a 15-lipoxygenase (15-LOX) inhibitor with an IC50 of 0.3 mM. Additionally, it acts as a platelet aggregation inhibitor with an IC50 of 0.23 mM. Asperenone also exhibits antifungal properties, inhibiting the growth of pathogenic fungi Ophiostoma crassivaginatum and O. piliferum, and may be utilized in research related to cardiovascular diseases and anti-infective treatments.Formule :C20H22OCouleur et forme :SolidMasse moléculaire :278.388Topoisomerase I inhibitor 8
CAS :Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.Formule :C24H21FN2O4Couleur et forme :SolidMasse moléculaire :420.43Steroid sulfatase-IN-4
Steroid sulfatase-IN-4 irreversibly inhibits human STS with a 25 nM IC50, useful for endometriosis research.Formule :C19H17ClN2O5SCouleur et forme :SolidMasse moléculaire :420.87AGN-204396
CAS :AGN-204396 is an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides).Formule :C32H44FN3O4Couleur et forme :SolidMasse moléculaire :553.71PI4KIIIbeta-IN-11
CAS :PI4KIIIbeta-IN-11 is a PI4KIIIβ inhibitor (mean pIC50=9.1) that can be used to study diseases caused by RNA viruses and Plasmodium falciparum.Formule :C33H39N7O3Couleur et forme :SolidMasse moléculaire :581.71ATX inhibitor 12
Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.
Formule :C30H34FN5O2Couleur et forme :SolidMasse moléculaire :515.62Granaticin B
CAS :Granaticin B inhibits the initial phase of RNA biosynthesis and exhibits activity against Gram-positive bacteria, mycobacteria (weak), and Trichomonas vaginalis, along with the ability to suppress tumor cells.Formule :C28H30O12Couleur et forme :SolidMasse moléculaire :558.53111-Demethyltomaymycin
CAS :11-Demethyltomaymycin is an antibiotic that exhibits antiviral activity against Escherichia coli T1 and T3 bacteriophages, along with antibacterial properties against Gram-positive bacteria. Furthermore, it shows cytotoxic effects on leukemia L1210 cells.
Formule :C15H18N2O4Couleur et forme :SolidMasse moléculaire :290.314Serratamolide
CAS :Serratamolide is a cyclic peptide antibiotic with activity against Gram-positive bacteria, mycobacteria, and fungi, although its potency is relatively weak.Formule :C26H46N2O8Couleur et forme :SolidMasse moléculaire :514.652Antimalarial agent 9
Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48MRS4738
MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].Formule :C30H24F3NO2Couleur et forme :SolidMasse moléculaire :487.51TCMDC-125431
TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.Formule :C25H27N3O2SCouleur et forme :SolidMasse moléculaire :433.57IDX-320
CAS :IDX-320 is an HCV protease inhibitor.Formule :C37H43F3N6O7S2Couleur et forme :SolidMasse moléculaire :804.9TLN-232
CAS :TLN-232, a synthetic heptapeptide, may inhibit cancer by targeting M2PK to disrupt tumor cell energy production.Formule :C36H49N9O7S2Couleur et forme :SolidMasse moléculaire :783.96TrxR-IN-5
TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC₅₀ of 0.16 μM. anti-proliferative and anti-metastatic.Formule :C26H22O3Couleur et forme :SolidMasse moléculaire :382.46Maltophilin
CAS :Maltophilin is a broad-spectrum antifungal antibiotic that exhibits no antibacterial activity against either Gram-positive or Gram-negative bacteria.
Formule :C29H38N2O6Masse moléculaire :510.62AS1940477
CAS :AS1940477 selectively inhibits p38 MAPK α/β, blocks proinflammatory cytokines in cells, and has anti-inflammatory effects in rats.Formule :C24H22FN5O2Couleur et forme :SolidMasse moléculaire :431.46Formadicin B
CAS :Formadicin B exhibits significant activity against various species of Pseudomonas, Proteus, and Alcaligenes.
Formule :C30H34N4O15Couleur et forme :SolidMasse moléculaire :690.61GS-9160
CAS :GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer.Formule :C20H18FN3O4SCouleur et forme :SolidMasse moléculaire :415.44Cytochalasin G
CAS :Cytochalasin G exhibits reversible inhibition of cytokinesis and also inhibits macrophage phagocytosis and exocytosis, among other biological activities.Formule :C29H34N2O4Couleur et forme :SolidMasse moléculaire :474.591DMP 728
CAS :DMP 728 is an antagonist of Glycoprotein IIb-IIIa.Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71Narbomycin
CAS :Narbomycin exhibits activity against Gram-positive bacteria.Formule :C28H47NO7Couleur et forme :SolidMasse moléculaire :509.675Chitinovorin A
CAS :Chitinovorin A is a β-lactam antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.Formule :C26H41N9O11SCouleur et forme :SolidMasse moléculaire :687.722TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Formule :C24H27N5O2Couleur et forme :SolidMasse moléculaire :417.5Deoxyfuconojirimycin hydrochloride
CAS :Deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-L-fucosidase.Formule :C6H14ClNO3Couleur et forme :SolidMasse moléculaire :183.63AZD2353
CAS :AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).Formule :C22H19ClFN3O3Couleur et forme :SolidMasse moléculaire :427.86S39625
CAS :S39625 is a stable, potent topoisomerase I inhibitor with anticancer properties, resistant to efflux transporters, inducing gamma-H2AX at nanomolar levels.Formule :C25H22N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.45AVE-1330A free acid
CAS :AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.Formule :C7H11N3O6SCouleur et forme :SolidMasse moléculaire :265.243-Hydroxyrifamycin S
CAS :3-Hydroxyrifamycin S is an ansamycin antibiotic that exhibits strong activity against Gram-positive bacteria, while its effectiveness against Gram-negative bacteria is relatively limited.Formule :C37H45NO13Couleur et forme :SolidMasse moléculaire :711.752Pluracidomycin C2
CAS :Pluracidomycin C2 is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacteria.Formule :C11H15NO9S2Couleur et forme :SolidMasse moléculaire :369.37Ceclazepide
CAS :Ceclazepide is an antagonist of cholecystokinin receptor.Formule :C30H32N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61DDCPPB-Glu
CAS :DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.Formule :C22H27N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.48AGN-795
CAS :AGN-795 is a biochemical.Formule :C14H20N2Couleur et forme :SolidMasse moléculaire :216.328PD-1/PD-L1-IN-16
PD-1/PD-L1-IN-16 is a potent inhibitor of PD-1/PD-L1 (IC50: 53.2 nM) and has shown research potential for tumour immunotherapy.Formule :C34H30N4O4Couleur et forme :SolidMasse moléculaire :558.63Epelmycin D
CAS :Epelmycin D exhibits activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans, and demonstrates efficacy against leukemia (L1210).Formule :C30H35NO11Couleur et forme :SolidMasse moléculaire :585.599FK-906 HCl
CAS :FK-906 HCl is a human renin inhibitor used for the long-term treatment of patients with essential hypertension.Formule :C40H64ClN7O7Couleur et forme :SolidMasse moléculaire :790.44FTI 276 TFA
CAS :FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).Formule :C23H28F3N3O5S2Couleur et forme :SolidMasse moléculaire :547.61Enpp-1-IN-7
Enpp-1-IN-7: potent enpp-1 inhibitor, broad specificity, potential in cancer/infectious disease research. (WO2021203772A1)Formule :C18H19N7O4SCouleur et forme :SolidMasse moléculaire :429.45KUSC-5037
KUSC-5037 inhibits HIF-1 (IC50 = 1.2 μM) and mitochondrial complex V/FoF1ATP synthase.Formule :C18H17F3N6O2Couleur et forme :SolidMasse moléculaire :406.13651Novokinin
CAS :Angiotensin AT2 receptor agonistFormule :C39H61N11O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :795.97GW-597901 cinnamate
CAS :GW-597901 cinnamate is a long-acting beta(2)-agonist.Formule :C34H46N2O8SCouleur et forme :SolidMasse moléculaire :642.80AMG-222 tosylate
CAS :AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.Formule :C39H47N9O6SCouleur et forme :SolidMasse moléculaire :769.91CU-2010
CAS :CU-2010 is a synthetic compound that reduces blood loss and aids recovery post-cardiac surgery.Formule :C37H42N6O6SCouleur et forme :SolidMasse moléculaire :698.83SHP2 IN-1
CAS :SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).Formule :C18H22Cl2N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.38Pyruvate Carboxylase-IN-2
CAS :Pyruvate Carboxylase-IN-2, erianin analog, inhibits PC with IC50s of 0.065/0.097 μM in lysate/cell assays, targets HCC.Formule :C21H22O8Couleur et forme :SolidMasse moléculaire :402.39ZL-Pin13
CAS :ZL-Pin13: potent Pin1 inhibitor (IC50: 67 nM), halts MDA-MB-231 cell growth, reduces Pin1 substrates.Formule :C24H23ClN2O3SCouleur et forme :SoildMasse moléculaire :454.97
