Autres inhibiteurs
Cette catégorie englobe une grande variété d'inhibiteurs qui ne rentrent pas dans les classifications standard mais qui sont néanmoins cruciaux pour diverses recherches biochimiques et pharmacologiques. Ces inhibiteurs peuvent cibler des voies, des enzymes et des interactions moléculaires uniques ou moins étudiés, fournissant des outils précieux pour des domaines de recherche spécialisés. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité ciblant de multiples objectifs biologiques et disciplines de recherche, vous permettant d'explorer de nouvelles avenues thérapeutiques et d'approfondir votre compréhension des processus biologiques complexes.
36012 produits trouvés pour "Autres inhibiteurs"
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P-gp modulator 1
CAS :P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulatorFormule :C41H72N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :689.02Kahweol linoleate
CAS :Kahweol linoleate, a semi-synthetic from coffee, blocks osteoclast creation, fights cancerous cells, prevents DNA damage, and reduces oxidative stress.Formule :C38H56O4Couleur et forme :SolidMasse moléculaire :576.85SK&F 108361
CAS :SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.Formule :C24H48N6O6Couleur et forme :SolidMasse moléculaire :516.67MDL-100173
CAS :MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.Formule :C24H26N2O4SCouleur et forme :SolidMasse moléculaire :438.54RSV-IN-7
CAS :RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) .Formule :C27H22F3N7O3Couleur et forme :SolidMasse moléculaire :549.50CD33 splicing modulator 1
Compound 1 modulates CD33, affects microglial cells, and may aid in neurodegenerative disease research.Formule :C25H25FN6OCouleur et forme :SolidMasse moléculaire :444.5AZD2353
CAS :AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).Formule :C22H19ClFN3O3Couleur et forme :SolidMasse moléculaire :427.86Phosmidosine
CAS :Phosmidosine inhibits cell cycle progression and morphological recovery in srcts-NRK cells. Additionally, Phosmidosine exhibits antifungal properties.Formule :C16H24N7O8PCouleur et forme :SolidMasse moléculaire :473.38Hypnophilin
CAS :<p>Hypnophilin exhibits multiple activities, including effectiveness against Gram-positive bacteria, Gram-negative bacteria, yeasts, molds, and tumors.</p>Formule :C15H20O3Couleur et forme :SolidMasse moléculaire :248.318CJ-887
CAS :CJ-887 is a STAT3 inhibitor.Formule :C34H45N6O10PCouleur et forme :SolidMasse moléculaire :728.73C20 Sphingomyelin (d18:1/20:1)
CAS :C20 Sphingomyelin (d18:1/20:1) (Compound SM:20:1) is a type of sphingolipid. This compound shows potential for research related to motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS).Formule :C43H85N2O6PCouleur et forme :SolidMasse moléculaire :757.11915(R)-Lipoxin A4
CAS :Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment andFormule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47Menoxymycin B
CAS :Menoxymycin B is an antibiotic with cytotoxic properties, inhibiting KB and N18-RE-105 cells with IC50 values of 0.22 μM and 0.023 μM, respectively.Formule :C25H31NO9Couleur et forme :SolidMasse moléculaire :489.515Lactaroviolin
CAS :Lactaroviolin is an aromatic derivative antibiotic that can inhibit the growth of Mycobacterium tuberculosis.Formule :C15H14OCouleur et forme :SolidMasse moléculaire :210.271Exatecan-amide-cyclopropanol
CAS :Exatecan-amide-cyclopropanol potently inhibits SK-BR-3 and U87 cancer cells (IC50 0.12 and 0.23 nM)Formule :C28H26FN3O6Degré de pureté :98.308%Couleur et forme :SolidMasse moléculaire :519.52Indinavir monohydrate
CAS :Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.Formule :C36H49N5O5Couleur et forme :SolidMasse moléculaire :631.82TrxR-IN-5
TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC₅₀ of 0.16 μM. anti-proliferative and anti-metastatic.Formule :C26H22O3Couleur et forme :SolidMasse moléculaire :382.46P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.4SP inhibitor 1
SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.Formule :C36H38N2O2Couleur et forme :SolidMasse moléculaire :530.7WAY-855
CAS :WAY-855 is an EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake.Formule :C9H11NO4Couleur et forme :SolidMasse moléculaire :197.19Prohibitin ligand 1
Compound 22i, a prohibitin ligand, protects the heart at nanomolar levels by inducing STAT3 phosphorylation.Formule :C20H22N2OCouleur et forme :SolidMasse moléculaire :306.4PF-06815345 hydrochloride
CAS :PF-06815345 HCl is an oral, potent PCSK9 inhibitor, IC50 13.4 μM, lowers PCSK9 in mice.Formule :C27H30Cl2FN9O4Couleur et forme :SolidMasse moléculaire :634.49AMPK Activator SC4
CAS :SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.Formule :C26H18ClN3O4Couleur et forme :SolidMasse moléculaire :471.89Medermycin
CAS :Lactoquinomycin A is a quinone antibiotic displaying activity against Gram-positive bacteria and some Gram-negative bacteria, though its efficacy is weaker against the latter and it is ineffective against fungi. It inhibits various cell lines, including lymphoma L5178Y progenitor cells, doxorubicin-resistant cells, bleomycin-resistant cells, human leukemia K562 cells, murine leukemia L-1210 cells, and murine leukemia P388 cells, with ID50 values (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013, and 0.03, respectively.Formule :C24H27NO8Couleur et forme :SolidMasse moléculaire :457.473DGY-08-097
CAS :DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.Formule :C60H76N10O14Couleur et forme :SolidMasse moléculaire :1161.3Mutalomycin
CAS :Mutalomycin is a polyether antibiotic with activity against Gram-positive bacteria, mycoplasma, and coccidia.Formule :C41H70O12Couleur et forme :SolidMasse moléculaire :754.987MB-7133
CAS :MB-7133 is an inhibitor of DNA synthesis.Formule :C17H21N4O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.34Antiviral agent 15
Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51Nolpitantium Free Base
CAS :Nolpitantium is a potent, selective NK1 receptor antagonist that inhibits substance P without affecting NK2/NK3 receptors.Formule :C37H45Cl2N2O2Couleur et forme :SolidMasse moléculaire :620.67T-3861174
CAS :T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.Formule :C26H25FN6O2Couleur et forme :SolidMasse moléculaire :472.51MEIS-IN-1
CAS :<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Formule :C24H21F3N2O4Couleur et forme :SolidMasse moléculaire :458.43Phellinsin
CAS :<p>Phellinsin selectively inhibits the activity of chitin synthase I and II, with IC50 values of 76 and 28 μg/mL, respectively. It also exhibits antimicrobial effects against pathogens such as anthracnose, rice blast fungus, Aspergillus fumigatus, and Trichophyton mentagrophytes, with a MIC ranging from 12.5 to 50 μg/mL.</p>Formule :C18H14O8Couleur et forme :SolidMasse moléculaire :358.30Seldomycin factor 1
CAS :Seldomycin factor 1 (XK 88-1) is an aminoglycoside antibiotic known for its broad-spectrum antibacterial activity.Formule :C17H34N4O10Couleur et forme :SolidMasse moléculaire :454.473Miyakamide B1
CAS :Miyakamide B1 is an antibiotic with insecticidal properties, capable of inhibiting the growth of brine shrimp. It displays moderate activity against Xanthomonas bacteria and inhibits P388 cells with an IC50 of 8.8 μg/mL.Formule :C31H32N4O4Couleur et forme :SolidMasse moléculaire :524.61eIF4A3-IN-6
CAS :eIF4A3-IN-6 is a potent eIF4A inhibitor, potentially used for treating eIF4A-related diseases like cancer. (US20170145026A1)Formule :C26H25N3O5Couleur et forme :SolidMasse moléculaire :459.49Antibiotic MA 144M2
CAS :Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.Formule :C42H55NO16Couleur et forme :SolidMasse moléculaire :829.88FTI 276 TFA
CAS :FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).Formule :C23H28F3N3O5S2Couleur et forme :SolidMasse moléculaire :547.61Cicaprost
CAS :Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Formule :C22H30O5Couleur et forme :SolidMasse moléculaire :374.47PNU-140457
CAS :PNU-140457 is a bio-active chemical.Formule :C14H14FN5O3Couleur et forme :SolidMasse moléculaire :319.291,6-Dihydroxy-2-chlorophenazine
CAS :1,6-Dihydroxy-2-chlorophenazine exhibits weak antifungal and anti-yeast activity.Formule :C12H7ClN2O2Couleur et forme :SolidMasse moléculaire :246.65Antitumor agent-187
CAS :Antitumor agent-187 (compound I) is an isoflavone derivative with antitumor activity. It exhibits IC50 values of 5.23 μM and 2.63 μM against A2780 and SKOV3 cell lines, respectively.Formule :C24H26N2O7Couleur et forme :SolidMasse moléculaire :454.476-Aminopyridine-3-thioamide
CAS :6-Aminopyridine-3-thioamide is a compound noted for its anticancer properties, capable of inhibiting the activity of specific enzymes that affect cell proliferation and survival. Furthermore, it has been studied for its potential to mitigate neurodegenerative diseases, exhibiting capabilities to enhance neural functions. The structural characteristics of 6-Aminopyridine-3-thioamide render it a significant bioactive molecule in compound development.Formule :C6H7N3SCouleur et forme :SolidMasse moléculaire :153.21MTSES sodium
CAS :MTSES sodium (Sodium (2-Sulfonatoethyl)methanethiosulfonate) is a negatively charged, membrane-impermeable methanethiosulfonate (MTS). This MTS compound can react with thiol groups to form mixed disulfides, frequently utilized in studying cysteine residues on proteins.Formule :C3H7NaO5S3Couleur et forme :SolidMasse moléculaire :242.27Nispomeben
CAS :Nispomeben is an effective non-opioid analgesic.Formule :C21H27NO4Couleur et forme :SolidMasse moléculaire :357.44NVP-CFC218
CAS :NVP-CFC218 is a novel potent and selective p53-HDM2 inhibitor.Formule :C37H45ClN4O4Couleur et forme :SolidMasse moléculaire :645.23SOAT-IN-1
CAS :SOAT-IN-1 (compound 40) is a potent and selective inhibitor targeting the sodium-dependent organic anion transporter (SOAT), exhibiting IC50 values of 1.6 µM for SOAT and 14.3 µM for NTCP.Formule :C20H16ClN3O6SCouleur et forme :SolidMasse moléculaire :461.88Evategrel
CAS :Evategrel is an inhibitor of platelet aggregation.Formule :C21H26ClNO7SCouleur et forme :SolidMasse moléculaire :471.95Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.Formule :C23H29N3O5Couleur et forme :SolidMasse moléculaire :427.49Copper(II) ionophore I
CAS :Copper(II) ionophore I is an active compound.Formule :C26H44N2S4Couleur et forme :SolidMasse moléculaire :512.90AX15910
AX15910 is a potent inhibitor of BRD4 and ERK5.Formule :C32H38N6O3Couleur et forme :SolidMasse moléculaire :554.7Scytalol A
CAS :<p>Scytalol A selectively inhibits the biosynthesis of dihydroxynaphthalene melanin in Lachnellula sp. A32-89, while not affecting the growth of the strain.</p>Formule :C15H18O6Couleur et forme :SolidMasse moléculaire :294.3Ledene
CAS :Ledene (Viridiflorene) is an essential oil produced by viridiflorene synthase.Formule :C15H24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :204.35Namitecan
CAS :Namitecan is an effective inhibitor of topoisomerase I. It has antitumor property.Formule :C23H22N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.44STING agonist-7
STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].Formule :C17H12N4O4Couleur et forme :SolidMasse moléculaire :336.3Luminacin G2
CAS :Luminacin G2 exhibits potent inhibitory effects on capillary formation (IC50 < 0.1 μg/mL).Formule :C25H36O8Masse moléculaire :464.55PBX-7011
CAS :PBX-7011, an active camptothecin derivative, binds to the DDX5 protein in cells and induces cell death through DDX5 protein degradation [1].Formule :C24H21N3O6Masse moléculaire :447.44Cycloepoxydon
CAS :Cycloepoxydon inhibits the NF-KB and AP-1 mediated secretion of alkaline phosphatase (SEAP) induced by Phorbol 12-myristate 13-acetate (PMA), with IC50 values of 1-2 μg/mL (4.2-8.4 μM) and 3-5 μg/mL (12.6-21 μM), respectively.Formule :C12H16O5Couleur et forme :SolidMasse moléculaire :240.252VEGFR-2-IN-17
VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.Formule :C21H14ClN3O2Couleur et forme :SolidMasse moléculaire :375.81TKL-IN-2
CAS :TKL-IN-2 (Compound 7m) is a TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. It exhibits excellent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus, while being safe for corn, wheat, soybean, and cotton. TKL-IN-2 is suitable for research in weed control in crop fields.Formule :C23H17ClF3N3OCouleur et forme :SolidMasse moléculaire :443.85ISR modulator-1
CAS :ISR Modulator-1 (Compound 212) acts as a regulator for the integrated stress response pathway (ISR).Formule :C20H21ClF4N4O4Couleur et forme :SolidMasse moléculaire :492.85Chitinovorin C
CAS :Chitinovorin C is a β-lactam class antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.Formule :C15H20N4O8SCouleur et forme :SolidMasse moléculaire :416.406Mycinamicin Ⅳ
CAS :Monamycin IV is an ester peptide antibiotic active against Gram-positive bacteria.Formule :C37H61NO11Couleur et forme :SolidMasse moléculaire :695.88Anti-inflammatory agent 16
Compound 14 is a peptidomimetic that significantly lowers TNFα, NO, CD40, and CD86, showcasing strong anti-inflammatory effects.Formule :C21H23N5O3Couleur et forme :SolidMasse moléculaire :393.44Mutatochrome
CAS :Mutatochrome (Citroxanthin) is a compound found in plants.Formule :C40H56OCouleur et forme :SolidMasse moléculaire :552.872PPARα/γ agonist 1
PPARα/γ agonist 1 is a potent and dual PPARα/γ partial agonist which is a promising prototype for the research of dyslipidemia and diabetes.Formule :C18H19NO2Couleur et forme :SolidMasse moléculaire :281.35DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formule :C32H33Cl2FN4O3Couleur et forme :SolidMasse moléculaire :611.53Lunacalcipol
CAS :Lunacalcipol is used for the treatment of Secondary Hyperparathyroidism.Formule :C28H42O4SCouleur et forme :SolidMasse moléculaire :474.7Juglomycin B
CAS :<p>Juglomycin B exhibits broad-spectrum antibacterial and antimycobacterial properties and is capable of inhibiting Ehrlich ascites carcinoma in mice.</p>Formule :C14H10O6Couleur et forme :SolidMasse moléculaire :274.226FCE-24379
CAS :FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.Formule :C20H22N4O2Couleur et forme :SolidMasse moléculaire :350.41LPA5 antagonist 1
LPA5 antagonist 1: selective, potent (IC50=32 nM), high brain permeability, studies inflammatory/neuropathic pain.Formule :C28H26N2O4SCouleur et forme :SolidMasse moléculaire :486.58KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Formule :C16H15ClFN5Couleur et forme :SolidMasse moléculaire :331.78Antiviral agent 7
Antiviral agent 7 is a peptide-based coating that kills viruses.Formule :C29H31F2N3O6Couleur et forme :SolidMasse moléculaire :555.57Lactoquinomycin B
CAS :Lactoquinomycin B is a quinone antibiotic with activity against Gram-positive bacteria and some Gram-negative bacteria, though its efficacy against Gram-negative species is weaker and it does not affect fungi. It inhibits various cell lines, including lymphoma L5178Y parental cells, doxorubicin-resistant cells, bleomycin-resistant cells, human leukemia K562 cells, and murine leukemia L-1210 and P388 cells, with ID50 (μg/mL) values of 0.43, 0.21, 0.19, 0.16, 0.2, and 0.12, respectively.Formule :C24H27NO9Couleur et forme :SolidMasse moléculaire :473.473KF 20274
CAS :KF 20274 is an adenosine A1 antagonist; purinergic receptor antagonist.Formule :C21H29N5OCouleur et forme :SolidMasse moléculaire :367.49PARP10/15-IN-1
PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].Formule :C13H10N2O3SCouleur et forme :SolidMasse moléculaire :274.3Halomicin D
CAS :Halomicin D is an ansamycin-class antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria.Formule :C43H56N2O12Couleur et forme :SolidMasse moléculaire :792.911NB-533
CAS :NB-533 is a macrocyclic peptidic BACE-1 inhibitor.Formule :C33H55N3O4Couleur et forme :SolidMasse moléculaire :557.812-n-Heptyl-4-quinolinol
CAS :2-n-Heptyl-4-quinolinol exhibits activity against Candida albicans, Staphylococcus aureus, Vibrio anguillarum, and Vibrio harveyi.Formule :C16H21NOCouleur et forme :SolidMasse moléculaire :243.34Haliangicin A
CAS :<p>Haliangicin A exhibits antifungal activity against filamentous fungi and also affects oomycetes, though it does not possess antibacterial properties.</p>Formule :C22H32O5Couleur et forme :SolidMasse moléculaire :376.49rel-MDM2/4-p53-IN-2
Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.Formule :C25H17Cl3FN3O3Couleur et forme :SolidMasse moléculaire :532.785(S),6(R)-DiHETE
CAS :5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47MSA-2 dimer
CAS :MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.Formule :C29H28O8S2Couleur et forme :SolidMasse moléculaire :568.66Protectin D1
CAS :<p>Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by nerve cells and is a potential cardioprotective agent.</p>Formule :C22H32O4Degré de pureté :99.72% - 99.79%Couleur et forme :SolidMasse moléculaire :360.49SphK2-IN-1
CAS :SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.Formule :C23H22ClF3N8OCouleur et forme :SolidMasse moléculaire :518.92Rhamnitol
CAS :Rhamnitol, the reduction product of L-rhamnose, can be observed during the metabolism of rhamnose in the body. Rhamnitol is promising for use in assessing intestinal permeability and studying carbohydrate metabolism.Formule :C6H14O5Couleur et forme :SolidMasse moléculaire :166.17Endophenazine A
CAS :Endophenazine A exhibits activity against Gram-positive bacteria and filamentous fungi such as Mucor and Penicillium, but demonstrates limited herbicidal effect on Lemna.Formule :C18H16N2O2Couleur et forme :SolidMasse moléculaire :292.332MraY-IN-1
MraY-IN-1 inhibits MraY (IC50: 140μM), fights E. coli K12, B. subtilis W23, P. fluorescens (MIC50: 7-46μg/ml), for antimicrobial research.Formule :C35H46N3O5Couleur et forme :SolidMasse moléculaire :588.76CGS 22652
CAS :CGS 22652 has thromboxane receptor antagonism combined with thromboxane synthase inhibition.Formule :C22H29ClN2O4SCouleur et forme :SolidMasse moléculaire :452.99S-2,3-Dicarboxyaziridine
CAS :S-2,3-Dicarboxyaziridine is a metabolite that can be isolated from Streptomyces species and exhibits antibacterial activity.Formule :C4H5NO4Couleur et forme :SolidMasse moléculaire :131.087UAWJ9-36-1
CAS :UAWJ9-36-1: potent broad-spectrum coronavirus Protease inhibitor; IC50 = 51 nM.Formule :C23H29N3O5Couleur et forme :SolidMasse moléculaire :427.49(R)-ONO-2952
(R)-ONO-2952 is the R-enantiomer of ONO-2952. ONO-2952 is selective and oral effective TSPO antagonist, with Kis of 0.330-9.30 nM inhibiting rat and human TSPO.Formule :C22H20ClFN2O2Couleur et forme :SolidMasse moléculaire :398.86Antiangiogenic agent 3
Antiangiogenic agent 3 blocks HUVEC cell migration, chemotaxis, and lowers Src, cdc42, MAPK gene expression.Formule :C19H20O7Couleur et forme :SolidMasse moléculaire :360.36ACT-281959
CAS :ACT-281959, a prodrug of ACT-246475, is a potent P2Y12 antagonist, better than Clopidogrel, effective orally, and in human trials.Formule :C38H55N6O14PCouleur et forme :SolidMasse moléculaire :850.85Furaquinocin A
CAS :<p>Furaquinocin A has the ability to kill HeLa S3 and B16 melanoma cells, yet it lacks antibacterial activity.</p>Formule :C22H26O7Couleur et forme :SolidMasse moléculaire :402.438TRPV1 antagonist 3
TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.Formule :C23H25N3OSCouleur et forme :SolidMasse moléculaire :391.53AY-22,252
CAS :AY-22,252 is an inhibitor of beef heart & rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Formule :C27H37NaO7Couleur et forme :SolidMasse moléculaire :496.57ZK159222
CAS :ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.Formule :C32H48O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.72Azirinomycin
CAS :Azirinomycin exhibits activity against both Gram-positive and Gram-negative bacteria.Formule :C4H5NO2Couleur et forme :SolidMasse moléculaire :99.088STAT3-IN-7
CAS :STAT3-IN-7, an orally active aryl sulfonamido azetidine compound, serves as a STAT3 inhibitor with anticancer activities.Formule :C30H26F5N5O4SCouleur et forme :SolidMasse moléculaire :647.62Cephamycin A
CAS :Cephamycin A exhibits weak activity against both Gram-positive and Gram-negative bacteria.Formule :C25H29N3O14S2Couleur et forme :SolidMasse moléculaire :659.639Crotocin
CAS :Crotocin exhibits bactericidal activity against Cryptococcus neoformans, Candida albicans, and Saccharomyces cerevisiae (brewer’s yeast), but it can be inactivated by blood.Formule :C19H24O5Couleur et forme :SolidMasse moléculaire :332.391PCSK9-IN-17
CAS :PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.Formule :C16H19N5OSCouleur et forme :SolidMasse moléculaire :329.42GNE-203
CAS :GNE-203 is a Met inhibitor.Formule :C30H29Cl2F3N8O3Couleur et forme :SolidMasse moléculaire :677.50Cinnatriacetin A
CAS :<p>Cinnatriacetin A exhibits activity against Gram-positive bacteria.</p>Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.402Bacithrocin D
CAS :Bacithrocin D (Thiolstatin D) inhibits various proteases and has the capability to prolong clotting time. It exhibits IC50 values of 124, 9, 0.85, and 0.01 μM against thrombin, factor Xa, trypsin, and papain, respectively.Formule :C17H25N5O3Couleur et forme :SolidMasse moléculaire :347.412Epopromycin B
CAS :Epopromycin B inhibits cell wall synthesis in lettuce protoplasts, demonstrating herbicidal activity. It also exhibits cytotoxicity in B16 melanoma cells, with an IC50 of 0.003 µg/mL.Formule :C21H38N2O6Couleur et forme :SolidMasse moléculaire :414.536Hexacyclinol
CAS :Hexacyclinol exhibits moderate activity against Gram-positive bacteria and can inhibit oxidant production in yeast polysaccharide-stimulated polymorphonuclear leukocytes (PMNL) at concentrations of 4–40 μg/mL. It suppresses the growth of L-930 and K562 cells with IC50 values of 1.4 μg/mL and 0.4 μg/mL, respectively, and has an IC50 of 10 μg/mL for HeLa cells. Additionally, Hexacyclinol shows antimalarial activity, with an IC50 of 2.4 μg/mL against Plasmodium falciparum.Formule :C23H28O7Couleur et forme :SolidMasse moléculaire :416.46Lactonamycin
CAS :Lactonamycin exhibits significant activity against Gram-positive bacteria, including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL), and VRE (MIC of 0.39-0.78 μg/mL). It also demonstrates inhibitory effects on various tumor cell lines such as L-1210, P388, S180, FS-3, Ehrlich, and B16-BL5 (IC50 of 0.06-3.3 μg/mL).Formule :C28H27NO12Couleur et forme :SolidMasse moléculaire :569.513Cepacin A
CAS :Cepacin A is an alkyne antibiotic with antibacterial properties, exhibiting a minimum inhibitory concentration (MIC) of 0.2 μg/mL against Staphylococcus. Additionally, Cepacin A displays a degree of toxicity in mice, with an LD50 of 30 mg/kg when administered intraperitoneally.Formule :C16H14O4Couleur et forme :SolidMasse moléculaire :270.28Quinocycline B
CAS :Quinocycline B is a quinone and other glycoside antibiotic that demonstrates resistance to Gram-positive bacteria.Formule :C33H32N2O10Couleur et forme :SolidMasse moléculaire :616.62Bacithrocin A
CAS :Bacithrocin C is a thrombin inhibitor that also suppresses factor Xa, trypsin, and papain, with IC50 values of 48 μM, 13 μM, 0.65 μM, and 0.02 μM, respectively.Formule :C20H31N5O3Couleur et forme :SolidMasse moléculaire :389.492Cedarmycin A
CAS :Cedarmycin A exhibits activity against Candida, Cryptococcus neoformans, and Aspergillus fumigatus with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL.Formule :C13H20O4Couleur et forme :SolidMasse moléculaire :240.296Decarestrictin M
CAS :Decarestrictin M is a decanolide isolated from a strain of Penicillium. It functions as an inhibitor of cholesterol biosynthesis.Formule :C10H16O5Couleur et forme :SolidMasse moléculaire :216.231Flagranone C
CAS :Flagranone C is a natural product identified within Arthrobotrys flagrans.Formule :C16H16O8Couleur et forme :SolidMasse moléculaire :336.29Naphthoquinomycin B
CAS :Naphthoquinomycin B is an antibiotic that exhibits activity against Gram-positive bacteria and fungi, and it inhibits the synthesis of fatty acids in Escherichia coli (E. coli).Formule :C40H47NO9SCouleur et forme :SolidMasse moléculaire :717.867Enaminomycin B
CAS :Enaminomycin B exhibits activity against both Gram-positive and Gram-negative bacteria.Formule :C10H11NO6Couleur et forme :SolidMasse moléculaire :241.197Clavamycin E
CAS :Clavamycin E is a clavulanic acid antibiotic.Formule :C11H17N3O6Couleur et forme :SolidMasse moléculaire :287.269Panosialin wA
CAS :<p>Panosialin wA inhibits α,β-glucosidase and mannosidase enzymes, but does not exhibit inhibitory activity against the influenza virus. However, it has a mild antibacterial effect.</p>Formule :C21H36O5SCouleur et forme :SolidMasse moléculaire :400.57Pyloricidin B
CAS :Pyloricidin B is an antibiotic specifically effective against Helicobacter pylori, showing potent anti-Helicobacter pylori activity. It exhibits no activity against other bacteria or yeast.Formule :C26H42N4O9Couleur et forme :SolidMasse moléculaire :554.63Octacosamicin A
CAS :Octacosamicin A exhibits activity against bacteria, yeast, and filamentous fungi, although its antibacterial effects are relatively weak.Formule :C31H52N4O9Couleur et forme :SolidMasse moléculaire :624.766Basidalin
CAS :Basidalin exhibits properties that allow it to combat Gram-positive and Gram-negative bacteria, as well as inhibiting the proliferation of L-1210 leukemia cells in mice.Formule :C6H5NO3Couleur et forme :SolidMasse moléculaire :139.109Chandrananimycin A
CAS :Chandrananimycin A exhibits activity against Mucorales fungi and shows efficacy against tumor cell lines such as CCL HT29, MFXF 529L, and MACL McF-7.Formule :C14H10N2O4Couleur et forme :SolidMasse moléculaire :270.24Curromycin A
CAS :Curromycin A exhibits antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. Additionally, it can inhibit the replication of the human immunodeficiency virus (HIV) and suppresses the growth of mouse melanoma B16 and leukemia P388 cells.Formule :C38H55N3O10Couleur et forme :SolidMasse moléculaire :713.857Haliangicin C
CAS :Haliangicin C exhibits antifungal activity against filamentous fungi and also acts on oomycetes, although it does not possess antibacterial properties.Formule :C22H32O5Couleur et forme :SolidMasse moléculaire :376.49Fluopsin C
CAS :Fluopsin C is a copper-containing antibiotic with potent activity against both Gram-positive and Gram-negative bacteria, as well as antitumor properties.Formule :C4H8CuN2O2S2Couleur et forme :SolidMasse moléculaire :243.795Pyripyropene B
CAS :Pyripyropene B is a potent inhibitor of acyl-CoA:cholesterol acyltransferase 2 (ACAT2). It effectively inhibits acyl-CoA:cholesterol acyltransferase with an IC50 of 117 nM.Formule :C32H39NO10Couleur et forme :SolidMasse moléculaire :597.653Gerfelin
CAS :Gerfelin inhibits geranylgeranyl pyrophosphate synthase (GGPP synthase) activity, with an IC50 of 3.5 μg/mL.Formule :C15H14O6Couleur et forme :SolidMasse moléculaire :290.268Dynemicin P
CAS :Dynemicin P is an antibiotic.Formule :C28H21NO9Couleur et forme :SolidMasse moléculaire :515.47Myxovirescin A
CAS :<p>Myxovirescin A is an antibiotic with activity against Gram-negative bacteria.</p>Formule :C35H61NO8Couleur et forme :SolidMasse moléculaire :623.8614-Hydroxyphlebiarubrone
CAS :4-Hydroxyphlebiarubrone is a quinone antibiotic. It exhibits weaker resistance against Gram-negative bacteria and possesses cytotoxic properties.Formule :C19H12O5Couleur et forme :SolidMasse moléculaire :320.30Phoslactomycin B
CAS :Phoslactomycin B exhibits relatively weak activity against Gram-positive bacteria but demonstrates stronger activity against fungi.Formule :C25H40NO8PCouleur et forme :SolidMasse moléculaire :513.561Dienomycin B
CAS :Dienomycin B exhibits mild antibacterial activity.Formule :C18H23NO2Couleur et forme :SolidMasse moléculaire :285.38Fusarin C
CAS :Fusarin C is a mutagenic compound found in strains of the Fusarium genus.Formule :C23H29NO7Couleur et forme :SolidMasse moléculaire :431.479Exfoliamycin
CAS :Exfoliamycin is a naphthoquinone antibiotic found in the Streptomyces strain Exfoliamycin Tu 1424, and it exhibits activity against Gram-positive bacteria.Formule :C22H26O9Couleur et forme :SolidMasse moléculaire :434.436Oximidine Ⅲ
CAS :Oximidine III is an antitumor antibiotic that selectively inhibits the growth of rat fibroblast 3Y1 cells and induces mutations in various tumor genes. The inhibitory effects of Oximidine III on vH-ras-3Y1, v-src-3Y1 cells, and normal 3Y1 cells have IC50 values of 14 nM, 4.5 nM, and 140 nM, respectively. Additionally, Oximidine III arrests cells with RAS or SRC mutations in the G1 phase of the cell cycle and increases the expression of p21WAF1.Formule :C23H24N2O6Couleur et forme :SolidMasse moléculaire :424.45Darlucin A
CAS :Darlucin A exhibits both antibacterial and antifungal properties, accompanied by mild cytotoxicity.Formule :C19H16N2O3Couleur et forme :SolidMasse moléculaire :320.342Carpetimycin D
CAS :Carpetimycin D exhibits potent activity against both Gram-positive and Gram-negative bacteria, including those that produce β-lactamase. Additionally, Carpetimycin D strongly inhibits β-lactamase.Formule :C14H20N2O9S2Couleur et forme :SolidMasse moléculaire :424.447Carzinophillin A
CAS :Carzinophillin A exhibits inhibitory effects on both ascites carcinoma and Yoshida sarcoma.Formule :C31H33N3O11Couleur et forme :SolidMasse moléculaire :623.607Curvulic acid
CAS :Curvulic acid exhibits relatively weak activity against both Gram-positive and Gram-negative bacteria.Formule :C11H12O6Couleur et forme :SolidMasse moléculaire :240.209Hynapene C
CAS :Hynapene C exhibits an inhibitory minimum inhibitory concentration (MIC) of 34.7 μM against Eimeria acervulina.Formule :C18H24O3Couleur et forme :SolidMasse moléculaire :288.381Acrylamidine
CAS :Acrylamidine exhibits weak antifungal and yeast activity.Formule :C3H6N2Couleur et forme :SolidMasse moléculaire :70.09Pyloricidin A
CAS :Pyloricidin A is an antibiotic effective against Helicobacter pylori, produced by Bacillus sp. HC-70. It exhibits strong anti-Helicobacter pylori activity and shows no efficacy against other bacteria or yeasts.Formule :C31H51N5O10Couleur et forme :SolidMasse moléculaire :653.76Deflectin 1a
CAS :Deflectin 1a is an antibiotic with activities such as lysing bacteria, lysing red blood cells, and inhibiting Ehrlich ascites cancer cells. However, its effectiveness can be neutralized by the addition of serum or serum albumin.Formule :C21H24O5Couleur et forme :SolidMasse moléculaire :356.412Enamidonin
CAS :Enamidonin is a lipopeptide antibiotic. It inhibits EGF-dependent [3H] thymidine incorporation in Balb/MK cells with an IC50 of 10 μg/mL and can restore the transformed SRCTS-NRK cells to their normal flat shape with an ED50 of 10 μg/mL. It exhibits no antibacterial activity.Formule :C37H51N7O7Couleur et forme :SolidMasse moléculaire :705.844Bis(N-methylthioformohydroxamate)nickel (II)
CAS :Bis(N-methylthioformohydroxamate)nickel (II) is a nickel-containing antibiotic that exhibits significant activity against both Gram-positive and Gram-negative bacteria, as well as antitumor properties.Formule :C4H8N2NiO2S2Couleur et forme :SolidMasse moléculaire :238.942Aspochalasin M
CAS :Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.549-cis-13,14-Dihydroretinoic acid
CAS :<p>9-cis-13,14-Dihydroretinoic acid (9CDHRA) is a selective retinoid X receptor (RXR) agonist with a Kd of 90 nM. It can ameliorate memory deficits caused by impaired RXR signaling in vivo. This compound shows potential for research in the fields of neuroscience and metabolic diseases.</p>Formule :C20H30O2Couleur et forme :SolidMasse moléculaire :302.451Glidobactin G
CAS :<p>Glidobactin G is an antitumor antibiotic with activity against pathogenic fungi and yeasts. Additionally, Glidobactin G prolongs the survival time of mice inoculated with leukemia P388 cells.</p>Formule :C27H44N4O7Couleur et forme :SolidMasse moléculaire :536.6612-Hydroxygentamicin B
CAS :2-Hydroxygentamicin B is an aminoglycoside antibiotic with activity against both Gram-positive and Gram-negative bacteria.Formule :C19H38N4O11Couleur et forme :SolidMasse moléculaire :498.52511-Deacetoxywortmannin
CAS :11-Deacetoxywortmannin is an antibiotic with potent antibacterial and anti-inflammatory properties, and it also exhibits anti-edema effects.Formule :C21H22O6Couleur et forme :SolidMasse moléculaire :370.396Bacithrocin B
CAS :<p>Bacithrocin B is a thrombin inhibitor that suppresses the activity of thrombin, Factor Xa, trypsin, and papain, with IC50 values of 84 μM, 17 μM, 1.7 μM, and 0.02 μM, respectively.</p>Formule :C19H29N5O3Couleur et forme :SolidMasse moléculaire :375.465Monamycin H1
CAS :Monamycin H1 is an ester peptide antibiotic that exhibits activity against Gram-positive bacteria.Formule :C34H56ClN7O8Couleur et forme :SolidMasse moléculaire :726.303-O-Demethylmonensin A
CAS :3-O-Demethylmonensin A is a polyether antibiotic produced by Streptomyces cinnamonensis (strain LO-63).Formule :C35H60O11Couleur et forme :SolidMasse moléculaire :656.84Feigrisolide D
CAS :Feigrisolide D is a lactone produced by Streptomyces griseus. It exhibits moderate inhibitory activity against 3α-hydroxysteroid dehydrogenase.Formule :C22H38O7Couleur et forme :SolidMasse moléculaire :414.533Queenslandon
CAS :Queenslandon exhibits moderate antifungal activity against fungi such as Streptomyces, Penicillium, Aspergillus fumigatus, and Aspergillus flavus, and has no effect on bacteria.Formule :C20H26O8Couleur et forme :SolidMasse moléculaire :394.42Diolmycin A1
CAS :Diolmycin A1 is an antibiotic known for its anticoccidial activity.Formule :C18H19NO3Couleur et forme :SolidMasse moléculaire :297.348KUS121
CAS :KUS121: VCP ATPase activity inhibitor (IC50=330 nM), protects cells from ER stress, assists in cerebral ischemia, and preserves vision in retinitis pigmentosa.Formule :C22H17FN4NaO3SCouleur et forme :SolidMasse moléculaire :459.45Dykellic acid
CAS :Dykellic acid is a RhoA inhibitor. It can suppress the migration and motility of B16 cells and inhibit the tubular formation of HUVECs. Dykellic acid shows potential for use in cancer research.Formule :C14H16O4Couleur et forme :SolidMasse moléculaire :248.274Exophilin A
CAS :Exophilin A is an antibiotic that exhibits activity against Gram-positive bacteria.Formule :C30H56O10Couleur et forme :SolidMasse moléculaire :576.76Herbimycin B
CAS :Herbimycin B, an ansamycin antibiotic, functions as an inhibitor of Src family kinases. It exhibits herbicidal effects on most monocotyledonous and dicotyledonous plants and can inhibit the activity of tobacco mosaic virus (TMV), HeLa cells, and Ehrlich cells.Formule :C29H40N2O7Couleur et forme :SolidMasse moléculaire :528.637Gentamicin C2
CAS :Gentamicin C2 is an aminoglycoside antibiotic.Formule :C20H41N5O7Couleur et forme :SolidMasse moléculaire :463.5691-Hydroxyoxaunomycin
CAS :1-Hydroxyoxaunomycin is an antibiotic that inhibits the growth of U210 cells as well as the synthesis of DNA and RNA, with IC50 values of 0.0005 μg/mL, 1.00 μg/mL, and 0.76 μg/mL, respectively.Formule :C26H29NO11Couleur et forme :SolidMasse moléculaire :531.509Eulicin
CAS :Eulicin is an antifungal agent that inhibits human immunodeficiency virus (HIV) infection and replication. It demonstrates broad-spectrum activity against both Gram-positive and Gram-negative bacteria and can be found in Streptomyces.Formule :C24H52N8O2Couleur et forme :SolidMasse moléculaire :484.722Fluvirucin A1
CAS :Fluvirucin A1 is a novel antibiotic effective against the Influenza A virus.Formule :C23H44N2O5Couleur et forme :SolidMasse moléculaire :428.61Cytochalasin M
CAS :Cytochalasin M exhibits various biological activities, including reversible inhibition of cytoplasmic division and the suppression of both endocytosis and exocytosis in macrophages.Formule :C30H37NO6Couleur et forme :SolidMasse moléculaire :507.618Micacocidin B
CAS :Micacocidin B is an antibiotic that exhibits exceptional activity against Mycoplasma species.Formule :C27H37CuN3O4S3Couleur et forme :SolidMasse moléculaire :627.34Acremonol
CAS :Acremonol exhibits activity against Gram-positive bacteria and fungi.Formule :C14H18O6Couleur et forme :SolidMasse moléculaire :282.2910-Deoxymethymycin
CAS :10-Deoxymethymycin (AntibioticYC 17) exhibits antibiotic activity against Gram-positive bacteria.Formule :C25H43NO6Couleur et forme :SolidMasse moléculaire :453.612Bagremycin A
CAS :Bagremycin A is identified in the actinobacterium strain Streptomyces (Streptomyces) Tu 4128. It exhibits weak antimicrobial activity against Gram-positive bacteria, Saccharomyces cerevisiae, and Candida albicans.Formule :C15H13NO3Couleur et forme :SolidMasse moléculaire :255.26916-Hydroxyroridin L-2
CAS :16-Hydroxyroridin L-2 is a member of the verrucarin subclass of antibiotics with antitumor properties.Formule :C29H38O10Couleur et forme :SolidMasse moléculaire :546.606Parimycin
CAS :Parimycin exhibits activity against Gram-positive and Gram-negative bacteria, as well as tumors, but shows no efficacy against fungi. It inhibits tumor cells such as GXF 251L, H640, LXFA 629L, MCF-7, and MEXF 514L, with an IC70 range of 0.9-6.7 μg/mL.Formule :C22H20O7Couleur et forme :SolidMasse moléculaire :396.39Pacidamycin 5T
CAS :Pacidamycin 5T is found in the bacterium Streptomyces coeruleorubidus [NRRL 18370].Formule :C36H44N8O12Couleur et forme :SolidMasse moléculaire :780.78KFA1982
CAS :KFA1982 is a novel and potent factor Xa inhibitor.Formule :C28H34ClN3O9S2Couleur et forme :SolidMasse moléculaire :656.17Pilatin
CAS :Pilatin exhibits inhibitory effects on both bacteria and fungi, and it strongly suppresses the incorporation of thymidine and uridine into DNA and RNA in Ehrlich ascites tumor cells.Formule :C21H26O7Couleur et forme :SolidMasse moléculaire :390.427Dihydrocompactin
CAS :Dihydrocompactin is an antifungal metabolite derived from Penicillium citrinum and acts as an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase).Formule :C23H36O5Couleur et forme :SolidMasse moléculaire :392.529Roselipin 1A
CAS :Roselipin 1A inhibits diacylglycerol acyltransferase (DGAT) in rats.Formule :C40H72O14Couleur et forme :SolidMasse moléculaire :776.9912-Hydroxybutirosin
CAS :2-Hydroxybutirosin is an antibiotic that can be found in Bacillus circulans.Formule :C21H41N5O13Couleur et forme :SolidMasse moléculaire :571.576AM Toxin II
CAS :AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.Formule :C22H29N3O5Couleur et forme :SolidMasse moléculaire :415.49Juglomycin A
CAS :Juglomycin A exhibits broad-spectrum antibacterial and anti-mycobacterial activity and can inhibit Ehrlich ascites carcinoma in mice.Formule :C14H10O6Couleur et forme :SolidMasse moléculaire :274.226Chicamycin B
CAS :Chicamycin B exhibits antitumor properties and has mild activity against gram-positive bacteria.Formule :C13H14N2O4Couleur et forme :SolidMasse moléculaire :262.26111-Hydroxynovobiocin
CAS :11-Hydroxynovobiocin exhibits activity against Gram-negative bacteria.Formule :C31H36N2O12Couleur et forme :SolidMasse moléculaire :628.625-Hydroxymethylblasticidin S
CAS :5-Hydroxymethylblasticidin S is a broad-spectrum antibiotic found in Streptomyces setonii.Formule :C18H28N8O6Couleur et forme :SolidMasse moléculaire :452.465Macquarimicin B
CAS :Macquarimicin B is an antibiotic.Formule :C22H28O6Couleur et forme :SolidMasse moléculaire :388.454Phoslactomycin C
CAS :Phoslactomycin C exhibits relatively weak activity against Gram-positive bacteria, but demonstrates stronger antifungal effects.Formule :C30H48NO10PCouleur et forme :SolidMasse moléculaire :613.6775-Hydroxymethyltubercidin
CAS :5-Hydroxymethyltubercidin is a semisynthetic antibiotic derived from tubercidin-5-carboxylic acid.Formule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.279Manumycin E
CAS :Manumycin E exhibits activity against Gram-positive bacteria and Escherichia coli, but has limited effect on other Gram-negative bacteria and none on fungi. It inhibits RAS farnesyltransferase and demonstrates modest cytotoxic activity against the human colorectal cancer cell line [HCT-116].Formule :C30H34N2O7Couleur et forme :SolidMasse moléculaire :534.6Pulvilloric acid
CAS :Pulvilloric acid is an antifungal antibiotic produced by the organism Pen. pulvillorum 504.Formule :C15H18O5Couleur et forme :SolidMasse moléculaire :278.30Defucogilvocarcin V
CAS :Defucogilvocarcin V is an antibiotic with activity against Gram-positive bacteria.Formule :C21H16O5Couleur et forme :SolidMasse moléculaire :348.349Phenazostatin A
CAS :Phenazostatin A is a phenazine compound known for its neuroprotective properties. It acts by scavenging free radicals, protecting N18-RE 105 neuronal cells from glutamate-induced toxicity, and inhibiting lipid peroxidation. Phenazostatin A inhibits glutamate toxicity in N18-RE-105 cells with an EC50 of 0.34 μg/mL.Formule :C28H20N4O3Couleur et forme :SolidMasse moléculaire :460.48Gentamicin X2
CAS :Gentamicin X2 is an aminoglycoside antibiotic.Formule :C19H38N4O10Couleur et forme :SolidMasse moléculaire :482.526Maniwamycin B
CAS :Maniwamycin B exhibits antifungal properties.Formule :C10H20N2O2Couleur et forme :SolidMasse moléculaire :200.278Phospholine
CAS :Phospholine is an antibiotic with IC50 values (μg/mL) of 3.37 for L1 210 cells, 2.20 for P388 cells, and 1.99 for EL-4 cells.Formule :C25H40NO8PCouleur et forme :SolidMasse moléculaire :513.56Pacidamycin 5
CAS :Pacidamycin 5 exhibits inhibitory effects on Pseudomonas aeruginosa. It is also effective against certain strains of Staphylococcus aureus and Escherichia coli.Formule :C36H44N8O11Couleur et forme :SolidMasse moléculaire :764.782Glycocinnasperimicin D
CAS :Glycocinnasperimicin D is a glycoside cinnamoyl iminohistamine antibiotic. It exhibits activity against both Gram-positive and Gram-negative bacteria. Additionally, Glycocinnasperimicin D inhibits leukemia L1210 cells, with an IC50 of 2.0 μg/mL.Formule :C30H50N10O9Couleur et forme :SolidMasse moléculaire :694.78Depsidomycin
CAS :Depsidomycin is an immunomodulatory antibiotic isolated from the culture broth of Streptomyces lavendofoliae MI951-62F2, exhibiting immunosuppressive properties. It primarily shows antibacterial activity against Gram-positive bacteria.Formule :C38H65N9O9Couleur et forme :SolidMasse moléculaire :791.978Dehydroindapamide
CAS :Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.Formule :C16H14ClN3O3SCouleur et forme :SolidMasse moléculaire :363.82GG-43
GG-43 is a potent inhibitor of LIN28. The IC50 value of GG-43 against human LIN28A is 4 μM [1].Formule :C21H21NO3Couleur et forme :SolidMasse moléculaire :335.4Veonetinib
CAS :Veonetinib (example 3) is an effective inhibitor of tyrosine kinase , exhibiting IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively.Formule :C27H28FN3O4Couleur et forme :SolidMasse moléculaire :477.53HYL001
CAS :HYL001 (compound 338) is a potent inhibitor of the TGFβ receptor 1 (ALK5), exhibiting approximately nine times the efficacy of its structurally related counterpart, galunisertib, in eliminating liver metastasis tumors generated in mice.Formule :C21H18N4OCouleur et forme :SolidMasse moléculaire :342.39K-Ras-IN-4
CAS :K-Ras-IN-4 (compound CP163) is an inhibitor of K-Ras.Formule :C31H28F4N6O3SCouleur et forme :SolidMasse moléculaire :640.65
